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How long does oxycodone stay in your system?

How long does oxycodone stay in your system?

Here, we review everything you need to know about the time frame for oxycodone drug testings and detection. We also review the possibilities for oxycodone addiction and what you can do if you need help with oxycodone addiction. Then, we welcome your questions about oxycodone or how to quit taking oxycodone at the end.

How do you take oxycodone?

Oxycodone comes as a liquid solution, concentrated solution, tablet, capsule, and extended-release tablet to take by mouth. Most doses of oxycodone are usually taken with or without food every 4 to 6 hours, either as needed for pain or as regularly scheduled medications. The extended-release tablets are taken every 12 hours. Extended-release tablets are supposed to be swallowed one at a time with plenty of water. The oxycodone concentrated solution is mixed with at least 1 ounce (30 milliliters) of juice or other liquid, or with a semi-solid food such as applesauce or pudding.

Usually, doctors start by prescribing lower doses of oxycodone and then increase this dose over time if the pain is still not under control.  This is to minimize some of the addictive qualities of oxycodone. However, after you taking oxycodone for a period of time, the body may become used to the medication, which means that an oxycodone tolerance has developed. This is the same reason withdrawal symptoms may appear after abrupt interruption of the drug administration. Restlessness, watery eyes, runny nose, sneezing, yawning, sweating are just a small part of the long list of symptoms.  On the other hand, oxycodone abuse is defined by crushing the pills, snorting or injecting the powder, taking bigger doses and/or taking oxycodone more often than prescribed.

Main oxycodone uses

Oxycodone is used to relieve moderate to severe acute or chronic pain. It belongs to the group of medicines called narcotic analgesics. Controlled-release oral tablet of oxycodone are indicated for cancer and other chronic pains and intended to be taken every 12 hours. In this way, oxycodone considered to be the next best option for cancer pain after morphine.

Peak levels and half life of oxycodone

Peak levels for oxycodone vary for different individuals, mostly due to the body weight, drug abuse history, age of course and slightly gender. On average, after taking a regular release pill with oral administration of 0,28mg/kg, the peak level would be reached at 1 hour. The half-life in this case would be 5 hours.

Oxycodone drug testing: How long does oxycodone stay in the body?

Because oxycodone is a synthetic drug there are special types of drug tests for oxycodone called “Extended Opioids” tests. These tests can detect oxycodone concentrations up to four (4) days after administration, depending on the kind of sample being tested.

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How long does oxycodone stay in blood?

Oxycodone blood concentrations are detectible up to 24 hours after the administration. Oxycodone and its major metabolites are measured in blood to monitor for clearance, abuse, to confirm a diagnosis of poisoning, or to assist in a death investigation.

How long does oxycodone stay in hair?

As with any other drug, a single human hair does not provide information about the current presence of drugs in the body. However it has pretty big time window, providing evidence for precise amounts of drug use and approximate timing of consumption in the last 90 days (or longer).

How long does oxycodone stay in urine?

Oxycodone and its metabolites are mainly excreted in the urine and sweat. Therefore, oxycodone accumulates in patients with renal impairment. Urine sample, tested for oxycodone, will show positive even 3- 4 days after the administration.

How long does oxycodone stay in saliva or sweat?

A saliva sample is the most commonly used, non-invasive route for a quick, spot-check drug test. This sample can give information about oxycodone use from 1 to 4 days after the administration.

Oxycodone and addiction

Although oxycodone is a very effective painkiller with lots of legitimate uses, it is also is highly addictive. When abused, Oxycodone can produce a heroin-like high and it is classed as an “opiate”.

Problems with oxycodone?

Do you think you have a problem with oxycodone? Please leave us you questions in the comments section below. We will do our best in providing you with a personal, accurate and prompt answer.

Reference Sources: Medline Plus: Oxycodone
National Library of Medicine: Observations on the urine metabolic ratio of oxymorphone to oxycodone in pain patients
National Institute of Health: Drug Information Portal: Oxycodone

Photo credit: timlewisnm

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41 Responses to “How long does oxycodone stay in your system?
Omar
10:56 am September 21st, 2014

I took oxycodone three times about two days ago for a cold with a very painful cough. I stopped taking it because it was making me nauseous. I’ve woken up in the middle of the night the last two nights and had to throw up. Not violently, or anything, I just wake up and my mouth is all water and my stomach feels wrong. I don’t feel sick, my cold is pretty much gone and I’m eating normal. I’m not sick during the day, the only thing different I’ve done recently was take the oxycodone so I think that’s what’s causing it. I know nausea is a common side effect, how long after taking it does it usually last?

12:37 pm September 25th, 2014

Hello Omar. There should be no longer lasting nausea. It’s probably all gone by now. Are you feeling better?

Omar
4:40 pm September 25th, 2014

Yea, it lasted three or four days, but it’s done now, thank you.

deanna
2:42 am September 26th, 2014

I am an addict but I am also in severe pain. I HATE my life, my addiction, but I don’t know how to quit AND deal with the pain. If I don’t find relief soon I would rather be dead. I have NO quality of life. I feel so hopeless and so helpless.

Don
3:08 pm September 30th, 2014

Hi Deanna,

I don’t know if this will help, but I just wanted to let you know that there is always hope. I just had surgery on my back (I had severe pain in my leg) and I am doing much better, but I thought at the time that I would never get better. I got to the point where I was pretty broken and my faith was tested, but I am convinced that God loves us and that Jesus still heals (even if it is through surgery). Hang in there, get some support, things will change.

Skippy
12:52 am October 5th, 2014

Hello, I did a 10 bag of smack, and a 5mg of oxy on Thursday. Will I be cool to pass a drug test this Monday? ,I have a relatively high metabolism, & weigh 101 pounds, 5’2 , it’s kinda hard to say.

Boyd
8:18 pm November 4th, 2014

My son is starting to snort oxy again. He did it yesterday. I want to start drug testing him. How long does it take to go through his system. When I drug test him, I don’t want to see the result of what he did yesterday. Thanks.

Paul Contin
11:40 pm November 23rd, 2014

I recently acquired a taste for OxyContin, since September this year I started “treating” myself to taking it at the weekend on a fortnightly basis – I would buy 20 tablets each containing 40mg, and start off with a 200mg explosion shortly after eating a treat lunch time meal (buffet lunch or a few of McDonald’s finest burgers with all the extras and the sides), a few hours later 120mg then last thing at night, 80mg – I would spend most of the day playing all the best retro console games on the old Skool golden era game consoles – after having my last 80mg dose at night I would drink a big dose of some Promazine liquid and drift away on the computer games for a couple of hours…the following day (Sunday) I repeat the same process as just mentioned, only on the Sunday it feels even better. The following day and a half I feel tired and a little agitated, then from Tuesday evening to Friday afternoon it’s agony, all the side effects and horribleness – then from Saturday all the way thru to the next Fri I feel quite normal – with no complaints. But on Saturday I know I’m going to do my fortnightly treat again. Should I stop? Should I be worried? Maybe…but on the fortnightly weekend I won’t have this stuff I save my money to buy a few grams of mkat and ketamine, knowing I’m not going to be in OxyContin agony pain for the next days…

Daniel
7:38 am December 10th, 2014

I have two 1.8 complex cysts on my kidneys and leasons on both kidneys. Had car wreak in 1981 and reptured spleen,lacerated liver. Also L2,L5 disk problems SERVERE PAIN WITH SCROLLEOSIS BUT HAVE BEEN ON THIS DRUG FOR PAIN 4 YEARS NOW AT 30MG.IS THEIR ANYTHING THAT WOULD WORK BESIDES DRUGS…

K class
3:04 pm December 11th, 2014

Your probably much better of sticking to ket and a bit of mkat rather than developing an addiction for oxycontin if I’m allowed to say that, I love the high and the nice effects that oxycontin can provide but I know only too well the horrors and the torture that come part and parcel with this highly addictive super-powerful pain killer. You have to remember this stuff is basically heroin that has been professionally developed in a lab with the aid of the governent so straight away this tells you oxycontin is provided for only the most extreme cases where the pain is so great it would simply be easier to die. I’m not condoning the use of ket and mkat but as long as it’s treated with respect and used in small amounts on the odd weekend, this is probably the safest alternative to using ANY of the class A drugs that are out there, OxyContin included with this. Be sure to understand that what you are tampering with here is a stigma free Heroin – would you go out and take Heroin? Of course not, we all know it’s wrong – its associated with misery, homelessness and filth – but OxyContin is incorrectly assumed as JUST being a lovely pain killer – it’s heroin – please understand this, don’t be fooled…for a lovely weekend on the stuff you will be paying for it for the next week with aches, pains, diarrhoea, sleepless nights, depression, feeling hopeless, the Chinese burns in your legs keeping you awake at nights is like the feeling of being tortured – would you really want to put yourself thru all that and still be craving more of the drug? It’s a nasty one – BE WARNED

Oxyhoneymoon
3:35 pm December 11th, 2014

I completely agree, I recreationally use OxyContin now and again, but also realising what I’m going to be in for, the shear pain and scary withdrawals that are going to be thrown into the mix is enough to put me off wanting to do it again for at least a few weeks, I will simply use another drug which isn’t a Class A – I don’t drink or smoke or stay on the same drug week in week out as this is what leads to dependence – I only treat myself once a week and I avoid amphetamine but will use a small amount of mephedrone, ketamine and also visit my local head shop where I may buy a packet of white powder which is a legal high which does a similar thing to Mephedrone. I enjoy using OxyContin on the odd occasion but will only do it once, but will make it worth my while by having 180mg, knowing and understanding that I will be paying for this amazing few hours by being subjected to a Heroin-like withdrawal for the best part of a week. Understand I don’t fool around with class A’s with the exception of OxyContin, I think the ultimate buzz which OxyContin is, it would be fair to say the payback is worth it, as long as it’s not on a regular basis.

Jack
4:23 pm December 14th, 2014

I am having problems at night with my nasal passages. I am having trouble breathing. I am taking oxycodone for pain from an accident two weeks ago. I am afraid that oxycodone is hurting my breathing. As a result I have not taken any oxycodone since last night. I do not know if I can now stand the pain without it, but I am trying. My question is do you think in the next day or two this will clear up my breathing problems in my nasal passages.

3:32 pm December 29th, 2014

Hi Jack. Have you talked to your doctor about this? If it is the oxycodone hurting your breathing you might need to switch medications or your doctor may need to adjust your dose. You should be examined to be sure what’s causing this reaction.

jane
12:35 am January 14th, 2015

My husband has been using oxycodone for about 12-15 years. And the last 4 years he has made some terrible choses and put our relationship in a mess. What kind of thing would this long term use do to his mind? Need to know.

5:12 pm January 16th, 2015

Hello Jane. Oxycodone can cause long lasting changes in brain function. I’d suggest that you consult with a pharmacist and a psychologist…and start to sort out the individual from the drug effects. I truly wish you the best!

jean
5:06 am January 21st, 2015

I was a pedestrian hit by a car and given oxycodone 5/325 my back and neck pain but was given hydrocodone 10.25 this last time is it the same? Which is stronger ? Are the nausea side affects worse?

steve
11:45 am January 24th, 2015

Ive been on them for years. I stop a week then im back into i knowi want to quit i dont want my everyday life be sonsumed of being high and not really even high just feeling normal just taking it so you feel bettere that is not a life to live be easier said then done right i just always find my sekf going bacj to them is it that i can control my high? Or do i have an addiction? I want to quit what are my options how do i do it and stay ckear. For life

Julie
4:38 pm January 28th, 2015

I have been given oxycodone for pain following surgery. After approximately 1 week, I have developed red rashy skin and I can’t stop scratching. How long before I feel some relief. Its been 3 days since taking any oxycodone.

11:49 am January 29th, 2015

Hi Julie. I’d advise you to go see a doctor, the reaction you have to this medication shouldn’t be overlooked.

Carmela
8:04 am January 31st, 2015

hi been on oxycondon 20mg twice a day sometimes I take up to 4,I ran out and can’t see my doctor for two weeks,I finished them four days ago and feel like hell,I really don’t wanna go back on them no more but wondering how long does this feeling last,I have been on them for years,cannot help this feeling of not wanting to do anything, I feel suicidal, don’t wanna feel like this help

3:55 pm February 3rd, 2015

Hello Carmela. Reach out to a hotline in the case that the depressive thoughts get too strong: 1-800-273-TALK (8255). Suicidal ideas, while strong at the moment, can pass but need to be addressed ASAP. Acute withdrawal from oxycodone usually takes 7-10 days, but if you think about suicide at any time, reach out for help.

claudia
8:13 pm March 13th, 2015

I was given Oxy after a surgery for pain. I had to take 2 pills every 4 hours up to 4 times a day for 3 days. Because it was making me so nauseous I stopped the 3rd day and 2 weeks after I am still experiencing nausea at least once a day. The doctor told me that these effects could last 2-3 weeks…is that right?

charles
9:01 pm March 20th, 2015

Does oxycodone lower testosterone levels?

3:10 pm March 23rd, 2015

Hi Charles. Although, the effect of oxycodone in human reproduction has not been adequately studied, Oxycodone has been linked to cases of impotence in both, men and women. Scientists found that opioids, like oxycodone, may influence the hypothalamic-pituitary-adrenal or -gonadal axes. The result of these influences were decreasements in testosterone levels.

Laura
11:56 pm April 29th, 2015

I was in a nearly fatal car accident 11 yrs ago. Brokke c1,2&6, arm had 6compound fractures,3 1/2 wk coma, lost my spleen,3brain bleeds obviously have a Traumatic brain injury and Post traumatic stress disorder. I have a new pain managment Dr. I take 4-5 oxycodone a day. Im going trough perimenopause.Hot flash my butt, I’ve been at it for 5constant days, urination rediculoss!!! I went to Dr TODAY and hes telling me my levels are not what they should be.Im eating 120+a mo and methadone. WHY IS HE REPORTING MY LEVELS ARE NOT WHERE THEY SHOULD BE. HELP EXPLAIN THIS PLEASE, HE TREATS ME LIKE CR*P WHAT DO I DO AND HOW CAN I CLEAR MY NAME. PLEASE HELP NOW….HE WANTS TO SEE ME EVERY 2WKS,150$ DISABILITY DOSENT ALLOW ME TO AFFORD THIS. PLEASE HELPIS IT MY SWEATING AND URINATION CAUSING THIS?

Teri
6:30 pm May 27th, 2015

I have taken tramadol for about a month. I took 2-3 a day I’m now off them for a week but I have taken the oxycodone for 4 days. A pill a day. I’m stopping them. So my question is how long is the withdraw stage.

11:24 am May 28th, 2015

Hello Teri. The worst effects will appear a day or two after you quit use, and then they begin to subside. Withdrawal is different for everyone, and so is the duration of symptoms. I suggest you check out the following article http://prescription-drug.addictionblog.org/how-long-does-tramadol-withdrawal-last/ to review the withdrawal effects time-line and learn what you can expect. I’d suggest you taper down your doses for a more milder detox, plus medications can help you manage symptoms successfully. Ask your doctor or a pharmacist for guidelines.

melissa
12:26 pm June 29th, 2015

My family was mad because I wiuld not sale my percet to them I take about 40 of them every 2weeks for chronic pain but my family called me a druggie because I wont sale them is 40 to much every two weeks if im in pain

12:28 pm June 29th, 2015

Hi Melissa. Are you prescribed by a doctor to take those 40 pills every 2 weeks? Do you really need them? Selling them is illegal and is not the answer, but if you are taking more and more, that may be concerning your family.

aj
12:50 am July 4th, 2015

I’ve been taking oxycodone 5 milligrams for 2 weeks to the surgery how long will take for me to get out of my system I weigh approximately 250 and 47 years old been drinking a lot of water I also been taking 5 milligrams volumes for about 2-3 months how long will it take for that to get out of my system

Cheryl
3:14 am July 14th, 2015

I’m tryin to wean off from taking 90mg daily of oxycodone. I cry uncontrolably, jerk, freeze, then burn up and immediately start freezing sgain. I’m now down to 1/2 pill twice a day, which estates to 15 MG per day. I had pancreatitus.

5:09 pm July 14th, 2015

Hi Charyl. Has your doctor suggested any prescription medication or over-the-counter meds that can ease your withdrawal symptoms? Maybe you are cutting back doses way to fast or not doing it gradually enough.

frankie
8:40 pm July 28th, 2015

i have been off oxies for seven days. Still having problems with my legs hurting& restless. also some sleep problems. How much longer will this last? any thoughts on what would help my legs. PS. Tapered off. Still went thru hell. Appreciate any feedback. Thanx.

Courtney
3:09 am July 29th, 2015

How long will it take for a person to detox from oxycodone if done at home

larry
11:48 pm July 30th, 2015

I was piss tested on 7/22/5015. I have a prescription for hydrocodone 10/325. However I get about 40 15mg oxycodone from the street at leasrt twice a month. the morning i was tested I had consumed about 30 mg. of oxycodone that morning. How will that affect my pee test?

will
9:40 pm August 1st, 2015

i take 20mg of oxycodone.. and sometimes i take a little more… i get mine from a doctor..i took a drug test last month.. i know i passed, because they never called me back.. when they take urine, do they measure how many milligrams of oxycodone in your urine. because im allowed 20mg a day.. but like i said, i have been taking a little more.. can i drink more water to lower the milligrams, or is there something i can take. or do they even measure the milligrams in your urine

Scott
11:55 pm August 1st, 2015

Hello guys and gals, I get prescribed oxycodone 5mg immediate release for kidney stones. My question is I took two on Friday and one Saturday, I have a job interview sometime this week with a law enforcement agency but even prescribed I don’t want it to show up. I’m 6’1″, 220, athletic build and my metabolism is pretty good. How many days am I looking at? Any help is greatly appreciated, thanks.

Chris
3:55 am August 4th, 2015

I have been taking oxycodone for pain but it is giving me bad constipation sometimes. Is there anything I can take that will help with this? I have taken stool softners before but after a while, it loses it’s affect. A quick response would be great, thank you!

5:47 pm August 6th, 2015

Hi Courtney. Your organism eliminates the same amount of all substances at home as in a facility. If you are planning to do this on your own, consult a doctor first. Some people, based on their health state, are better off detoxing in a detox center under medical professional’s supervision. However, if your doctor gives you clearance to withdraw and detox at home, you will also be prescribed medications to help you with withdrawal symptoms.

Keith
5:00 am August 14th, 2015

I’ve been taking oxycodine 30 mgs for pain for about 5 weeks when I stop I go thru bad withdrawal how do I taper off completely without going thru those feeling? Is there another medication that can help me get off?

10:36 am August 14th, 2015

Hello Keith. The generally recommended tapering rate is 10-20% off your current dose, lowered every week or every other week. Still, I believe it’s best to consult your doctor or a pharmacist about tapering doses and how to manage withdrawal symptoms.

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