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Methadone

What is methadone?

Methadone is a synthetic opioid analgesic that is primarily a mu-opioid agonist. It was developed in Germany during the Second World War as a narcotic pain reliever that can treat moderate to severe pain. It is also used as a substitute drug in the treatment of morphine and heroin addiction. Methadone works by depressing the nervous system and changing the way the brain perceives physical and psychological pain.

Methadone is prescribed to people who are trying to quit heroin in the form of a green liquid for oral use. But it can also be found as a tablet or as an injection. Methadone is also found under other names, such as Amidone, Chocolate chip cookies, Fizzies, Heptadon, Phy, Symoron, and the brand names Dolophine and Methadose.

Why do people use methadone?

Methadone is the most frequently prescribed medication in the treatment of opiate or opioid dependence. In addiction treatment, it’s used to prevent withdrawal symptoms that follow the cessation of drug intake. Still, methadone is used to relieve moderate to severe pain that isn’t successfully relieved by non-narcotic painkillers. and because methadone impairs the action in the cough center,  doctors also prescribe it to patients with terminal lung cancer to control intractable coughing.

Routes of administration for methadone usually include:

  • intramuscular injection
  • intravenously
  • orally
  • subcutaneous injection

Still, people abuse methadone illegally in order to achieve euphoric effect. Even though it doesn’t create the same “high” as other drugs, it can trigger pleasant and enjoyable sensations of well-being, and many users continue to repeatedly seek them out.

Methadone effects

Methadone mainly depresses the nervous system, and its sedative effects start quickly after initial administration and can last for several hours. Some of the effects of methadone are:

  • enhanced feelings of relaxation and detachment
  • impaired function of the respiratory system
  • reduced physical and psychological pain
  • relief of anxiety
  • slower bodily functions

With recreational use, methadone can cause addiction. Other adverse side effects include:

  • allergic reaction
  • confusion
  • constipation
  • decrease of libido
  • difficulty urinating
  • irregular heart rate
    limb swelling
  • itches and hives
  • mood changes
  • rashes

Call your doctor for any unusual problems you’re experiencing with methadone. When using methadone in higher doses, users feel sleepy. If the dose is too high a user can fall into coma or stop breathing. Likewise, mixing methadone with alcohol or with benzodiazepines can have serious consequences, usually and most likely the result is an overdose and this can lead to a coma or respiratory failure and death.

Is methadone addictive?

Methadone is a relatively addictive substance. Users are expected to develop methadone dependency and/or tolerance to the drug. The development of psychological dependence varies, though, and is one of the hallmark symptoms of addiction. Because unpleasant methadone withdrawal symptoms manifest in dependent users whenever doses are lowered or are not available, even people who are on a monitored maintenance program may find it impossible to reduce their dosage.

If you or a loved one think that you are addicted to methadone, help is available. In fact, you mights consider entering a methadone addiction treatment center or a methadone detox facility to safely come off the medication. Inpatient treatment can monitor your progress and work to address your physical and mental well being. This is an important step of the recovery process, since it gives the patient all the needed tools to continue living an addiction free life. More here on Addiction Blog about how to address problems with methadone.

Methadone

35 How is methadone prescribed?

How is methadone prescribed?

June 5th, 2015

Methadone is prescribed through a medical doctor for pain. But when prescribed for people who are coping with drug addiction, there are many regulations for its prescription. More on methadone prescriptions here.

35 Does methadone help with opiate withdrawal

Does methadone help with opiate withdrawal

May 30th, 2015

Yes, methadone lessens the symptoms of opiate withdrawal blocks the effects of opiate drugs. More on how methadone can help with withdrawal here.

3 Why aren't people receiving medication assisted treatment? (and why access is so important)

Why aren’t people receiving medication assisted treatment? (and why access is so important)

April 6th, 2015

Why push for medication assisted therapies in the treatment of heroin or opioid addiction? An in-depth Q&A here with Paul Samuels, the Director and President of the Legal Action Center on why and how people SHOULD be able to access medications for addiction treatment.

24 The real dangers of methadone

The real dangers of methadone

March 2nd, 2015

Tolerance to and dependence on methadone can develop with chronic or indefinite use. What are some of the other dangers of long term methadone use? We review here.

184 Methadone overdose: How much amount of methadone to OD?

Methadone overdose: How much amount of methadone to OD?

August 15th, 2014

What are the signs and symptoms of methadone overdose? And how much methadone does it take to OD? We review here.

77 Mixing methadone with alcohol

Mixing methadone with alcohol

July 5th, 2014

Methadone and alcohol are two substances that should not be used together. Dangerous complications including respiratory problems, low blood pressure, a weak heart rate, and coma are possible. More on risks of mixing the two here.

5 What is methadone used for?

What is methadone used for?

May 1st, 2014

Methadone is used to treat individuals who suffer from addiction on heroin and narcotic pain medicines or as a pain reliever. More on its legal, illegal, and problematic uses here.

223 How long does methadone last?

How long does methadone last?

April 11th, 2014

How long does it take before methadone wears off? Generally, after a single oral dose effects can last from 6 to 8 hours, depending on patterns of use. More on duration of methadone effects here.

53 How to withdraw from methadone

How to withdraw from methadone

January 12th, 2014

The best way to withdraw from methadone is using tapering protocol under medical supervision. More on what to expect as you withdraw from methadone here.

3 What is methadone withdrawal?

What is methadone withdrawal?

December 14th, 2013

Methadone withdrawal is a process during which the body normalizes after a period of drug dependence. Methadone withdrawal symptoms usually mimic the flu and persist for 7-10 days after last use. More on methadone withdrawal here.

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Leave a Reply

9 Responses to “Methadone
Kate
2:15 pm May 28th, 2017

I took methadone on Friday the 20 of may would you no when it should be out of my urine plz I haven’t taken it since December please I need to no

Lydia @ Addiction Blog
3:16 pm May 29th, 2017

Hi Kate. Usually, methadone metabolites can test positive for 2-4 days in urine after last dose. This timeframe is longer for heavy or/and chronic users. If you want to learn more about drug testing, download our free e-book ‘The Definitive Guide To Drug Testing’ here: http://addictionblog.org/ebooks/the-definitive-guide-to-drug-testing/

Elisabeth
10:35 pm July 17th, 2017

Hi I truly need help to find a answer we got off the opiates to go right back to them I was thinking if I can get 200.000 signatures can I can I get doctors to be able to keep the people’s on methadone that sign a contract of only that for the rest of there lives knowing the effects subox has a contract that’s why these doctors are getting something out of it why would the doctor I just saw want me off methadone and up my oxymoron 15mg to 4 a day I was taking one and 4 methadone ,Maybe cause next door he owns a skybox clinic isn’t that against the law somehow ,my boyfriend’s in trouble as of the 16th we need another doctor fast we are so scared he’s on 270 a month we are both hiv was hep c he’s a hemophilia person what can we do please advice me if we have to move we will we have no choice for a decent life unless we stay on what we have been on for 15 years anyone that may have any ideas ya can write. thank you I’m in S.C ( for now ) !!!!!!

Lydia @ Addiction Blog
6:37 pm July 27th, 2017

Hello Elisabeth.

You should have access to methadone.

Please contact the following state authorities to talk about the issue directly.

1. http://www.behavioralhealthofsc.org/behavioral_health_services.html

Laura Stuckey, BHSA Executive Director
2711 Middleburg Drive, Suite 205
Columbia, SC 29204
803.252.0268

info@bhsasc.org

2. South Carolina
Bettye Harrison
Coordinator of Adult Services
Department of Alcohol and Other Drug Abuse Services
3700 Forest Drive, Suite 300
Columbia, SC 29204
Phone: (803) 734-9556
Fax: (803) 734-9663
E-mail: BHarrison@daodas.state.sc.us

3. SOUTH CAROLINA
Virginia Ervin, B.S.N., CARN, COHN
State Opioid Treatment Authority
South Carolina Department of Alcohol and Other Drugs
101 Executive Center Drive, Suite 215
Columbia, SC 29201
Phone: (803) 896-4860
Fax: (803) 896-5984
Email: vervin@daodas.state.sc.us

Brent Addict
4:11 pm October 2nd, 2017

I know of at least 2 people who have stopped methadone and everything else for over 10 years. My wife at has been clean for 14 and my brother for 11. I just went COLD TURKEY from 400 mg a day yes 10 mg per ml 400mg sometimes I double dosed it. I was also taken lots of benzos, so I’m doing a benzo Methadone detox. I have been 45 days and I expected it to be a lot worse, I thought it might kill me. I still don’t feel great but it gets better every week, not every day. Just thought I would let you know it is possible. If you or somebody reply I can give you some advice if you would like. Don’t listen to people who say it’s not possible almost everything is. It’s up to you who you listen to. I hope you pull it off you will feel so much better mentally and physically. If you are suicidal go to a 30-day rehab first or make sure you have somebody with you because it get’s a little rough. It is doable some people like to complain a lot I did ‘but my wife would say your pain isn’t anything compared to what you have done to me over the years. So I have to just sit with my mouth shut lol. It is a serious detox you just need to tuff it out and things get better. Just remember one pill one-shot some methadone bub will send you right back. Addicts can normally only control the first use then they are out of control again. Just do it you’ll never know till you try

Roseanna
1:35 am January 27th, 2018

Can you tell me how long methadone metabolites stay in your urine I was told 14 days but I still had it in my urine after 25 thank you

Lydia @ Addiction Blog
3:19 pm January 30th, 2018

Hi Roseanna. The detection period for long-term users is longer. If you like to learn more about drug testing, download our free guide here: http://addictionblog.org/ebooks/the-definitive-guide-to-drug-testing/

Nick
8:46 am February 11th, 2018

Help. I’m taking 74mg methadone liquid every morning. I have been on it for almost 18 months. I do no other drugs besides the legal weed. I just started a new job that requires me to look my best, talk to people . Great customer service because I am a server at a upscale steakhouse. Things are going great besides the methadone sweats!!! They are horrible and my co workers might be thinking I’m all fucked up on something cause of all the sweat on my face and hairline and also my back. Can anyone please help. I have tapered my dose down 2mg each week. Tried vitadone didn’t work

Lydia @ Addiction Blog
12:22 pm February 14th, 2018

Hi Nick. If you want to quit methadone, the safest way to do it is by slowly reducing the daily dose. I suggest that you consult with your doctor to help you plan an individualized tapering schedule. Also, download our free e-book ‘How To Quit Opioid Painkillers’ to learn more about opoids and how to deal with them: http://addictionblog.org/ebooks/how-to-quit-opioid-painkillers/

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