How long does Wellbutrin withdrawal last?

Wellbutrin (bupropion) withdrawal can last and fluctuate in severity over the course of several weeks. More on the duration of withdrawal from Wellbutrin here.

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Thinking about quitting Wellbutrin?

Wellbutrin, also known as bupropion, is used to treat long term depression and some versions of the medication are used to withdraw from nicotine and to help people stop smoking. Because Wellbutrin is used to treat long term depression, doctors expects people to develop a dependency on bupropion over time. So, if’ you’ve been taking Wellbutrin daily for some time and suddenly decide to stop taking Wellbutrin, you will experience withdrawal symptoms.

Here, we explore the withdrawal process from Wellbutrin and what you are can expect over the course of a few weeks after cessation. Plus, more on whether or not getting addicted to antidepressants is possible.  Then, we invite your questions about Wellbutrin at the end.

How long until Wellbutrin withdrawal starts?

In general, withdrawal from Wellbutrin or a generic form of buproprion can start any time you miss a dose or after the effects of your last dose have worn off. In this way, you can feel the onset of withdrawal very quickly after the last dose of Wellbutrin has worn off. Anti-depressants like Wellbutrin can trigger withdrawal symptoms like:

  • agitation
  • anxiety
  • confusion
  • fatigue
  • headache
  • insomnia
  • rebound depression

Wellbutrin withdrawal: how long?

Different people will have different reactions to withdrawal from Wellbutrin. Most who are on regular doses of burpopion have been using it for long extended periods of time so most will go through withdrawal. The intensity and how long withdrawal lasts depends on the tapering schedule recommended by a physician. Those who go cold turkey experience more severity and dangerous withdrawal symptoms.

However, keep in mind that when withdrawing from anti-depressants like Wellbutrin, the biggest thing you will have to face is the original symptoms of depression you were using the medication for. Many times, this depression comes with mood swings, anxiety, and irritation that can be present and last long after you have stopped taking Wellbutrin. Such symptoms make getting off the medication extremely difficult.

Still, this process and the side effects that arise can be made easier with appropriate Antidepressant Withdrawal And Detox Treatment Programs that work to make quitting Wellbutrin feel as safe and comfortable as possible.

Wellbutrin withdrawal timeline

Since it is recommended that you taper off Wellbutrin to reduce the severity of withdrawal symptoms, here we will discuss withdrawal as if you were stopping cold turkey.

24 – 72 hours Wellbutrin withdrawal: You are at risk for seizures during these hours. You may also experience flu like symptoms making you severely sick. You may experience uncontrolled crying and mood swings accompanied with worsened depression. Erratic thoughts are also common during the first few days of Wellbutrin withdrawal.

Week 1 Wellbutrin withdrawal: During the first week of Wellbutrin withdrawal, you can be really tired and need more sleep. Continued increased depression can be expected, or feeling like you are out of the body. Mental fog and tense muscles can also manifest during this time.

Week 2 Wellbutrin withdrawal: Physical symptoms should begin to ease and your body should feel a little better by the second week after you stop taking Wellbutrin. But expect that adverse symptoms in regards to your mood to persist. It may be hard to sleep as nightmares may accompany a depressed emotional state.

Week 3-4 Wellbutrin withdrawal: It is possible that you gain weight in the first three to four weeks after you stop taking Wellbutrin. Rebound depression can affect you in even more intense ways. Symptoms of depression can make it hard to abstain from bupropion and some people start taking Wellbutrin again in order to address these feelings. Sometimes people will start a different SSRI or antidepressant medication to treat present depression.

How long do Wellbutrin withdrawal symptoms last?

Symptoms of Wellbutrin withdrawal can begin shortly after you have stopped taking Wellbutrin. And you can expect to experience physical symptoms for several weeks. Be advised that symptoms of bupropion withdrawal can fluctuate. After the first few weeks of stopping Wellbutrin, psychological symptoms or disorders can resurface and last for several months afterward. In general, it can take a long time to treat the psychological conditions that underly Wellbutrin use.

How long Wellbutrin withdrawal questions

If you have any more questions regarding withdrawal from Wellbutrin please ask. We do our best to respond to your question accurately and promptly. Also feel free to share your own experience of withdrawal from Wellbutrin. What did you go through? What helped?

Reference Sources: Pub Med Health: Bupropion
FDA: Wellbutrin
FDA: Medication Guide
National Library of Medicine: Bupropion-Associated Withdrawal Symptoms
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. I stopped taking wellbutrin on the 20th March so approx 2 weeks ago. I am struggling nightly with sore legs. Numbness of the feet and hands.
    Is 5here at advice on how to deal with this as I am unable to sleep. May thanks Je

  2. I quit taking wellbutrin 300xl after being on it for seven years. I quit cold turkey and used supplements to ease the withdrawal. Fish oil, zinc, magnesium, b12, and a lot of coffee. After just two days my sex drive was back! I am two weeks out now and I will never go on this horrible drug again. Good luck to all.

  3. I was taking wellbutrin 300mg an celexa .20mg I think for 7 years an I quit taking them almost a 8 months ago. I decided to take them again 3 days ago an I decided to take them an my high dosage of wellbutrin an I didnt have my low dose of it . Only my high dosage one that I was on before. Well on the 2 days I was on it , I felt no emotion an I zoned out an it made me tired. I took it for 2 days an It gave me no appetite an i was not feeling good so i stopped takeing them for 2 days an I’ve been shaking for a few days an I dont know what to do

  4. what if someone was only taking Wellbutrin for 3 weeks? he took 1/2 a pill today. How long should he do that for? and then 1/4?

  5. I have decided to stop Wellbutrin after 3 weeks. My doctor told me to just stop taking it, that there are no side effects. I felt them after starting the med, experience mild ones daily, and even missed one dose and felt them. She said it’s not true, in regard to side effects, and would not taper me off since it’s been such a short time. Today is day one. I have a big event coming up a week from today and am very concerned about how I will be feeling. Are these feelings justified? Thank you for any feedback you can provide me.


  6. I was on 450mg for two years quit cold turkey it’s been 2months now how much longer will these withdrawals (anxiety insomnia fatigue tired no motivation) last my dr should have told me about this before starting Wellbutrin

  7. Hello, I had to stop my Wellbutrin bc it was dropped my our coverage. I had enough to get me through the month but unfortunately I went three weeks without it. I begun to suffer from extreme migraines. I finally got a secondary provider and was approved to have my scripts renewed. I have been back on it now for 2 1/2 weeks but my migraines are still really bad. Do you have any advice if these symptoms of discontinuation will go away now that I am back on it. My doctor didn’t seem to concerned bc I can tolerate pain pretty well but these migraines have put me in the ER three times in one month. She upped my dose to 300xl to see if that might help and if it does them we will eventually drop back down to the 150 that I have always taken. Any advice would be greatly appreciated.

  8. Hi. I’m in my 2nd week coming off 150 mg of zyban. I’ve been taking it for 4 years. It’s very expensive too. I’ve gone pretty much cold Turkey and experienced only slight agitation but a noticable drop with sexual dysfunction. I took it at first to address that side effect and it actually improved it. I’m just curious whether the libido will return once it’s out of my system. I’m 36 on good shape and know how to deal coming off antidepressants and so far so good.

  9. Hi, I am a 53 year old man with Cerebral Palsy and have been on Wellbutrin for probably five years. My situation is a bit weird and different. The Pharmacy I use is switching over to another big chain of Pharmacies. During the transition they are having a lot of computer gtches. There system showed I picked up this months supply last week, witch I did not do. They say they cannot give me another supply until June 2nd. Unfortunately, I am having withdrawal symptoms, flu like, confusion, moodswings ,etc. My doctor has even tried to get them to refill the prescription, and no luck. Normally I could ride it out ten days, but between a retirement party and leaving for Europe on June 4th, I cannot deal with withdrawals. Do you have any suggestions?


  10. I have only taken Wellbutrin for only a week. Will there be a lot of side affects. I have not taken any for two days. Am I ok

  11. I have been taking 150 msg of Wellbutrin for about 4 months it was extremely helpful for winters depression and seemed to have fewer side effects than the SSRI anti- depressants. About tens days ago I noticed huge welts on the side of my left thigh. I atributed it to spider bites and continued to take the prescribed dose of 150 mg of bupropion. Within a few days after that more bumps appear on my arms and upper legs so I stopped taking The Wellbutrin immediately. I have been off of it for a week now and have noticed hard bumps like cysts on my legs and arms and hands. I am so stiff and achy and very tired, as well as mentally foggy. I thought maybe it was due to the exercises I was doing but this is a different kind of stiffness and aching. I can hardly muster up the energy to get through a very easy exercise class. It’s very scary. I am hoping and praying these symptoms will subside. Any support or further info would be appreciated. My doctor just recommended I stop taking it so I did. It has been awful ! Never again. Thanks for listening. Patricia

  12. I have been on Bupropion SR 150mg to treat CFS for about 1.5 months and it has been successful but I don’t like the side effects (constipation or diarrhea) and would like to withdraw. How should I do it? I’m now taking 1/2 a pill twice daily. Thanks

  13. I took bupropion five years ago and it was great! I weaned off one pill every other day for a week then every two days etc until I just stopped. I don’t remember having withdrawals. My depression came back and I started on 300 mg xl. After taking it for about two weeks I forgot a dose. I waited until the next dose time the next day to take one. A couple of days later I forgot a dose again. I took it the next day and as the day went on I became more and more anxious and agitated. I started having a panic attack while driving. I got home thankfully and went to bed. For the next 5-6 hours I felt a tremor through my whole body muscle twitches tense shoulders and neck which was also hot. My skull felt like it was being squeezed and I had shortness of breath. Also numb and tingly and really cold hands and a headache with slight ringing in my left ear. I was able to calm down whenever I tried to stop tensing my muscles and tried deep breathing. I slept and woke several times through the night. This morning I feel better but still slightly anxious. I want to stop cold turkey from this point on but I don’t know if it will bring the panic attack back which was horrible. I thought I was dying. I have to go to work and be able to perform my job without feeling like I’m about to have a panic attack. I called my dr and left a message but she hasn’t gotten back to me. Please please respond and advise. What is happening to me? Is it withdrawal from forgetting doses? Is it because I took a pill after forgetting a dose? I don’t know what to do and I have to go to work tomorrow by freeway and I’m terrified of having another panic attack behind the wheel.

  14. I’ve only been taking welbutrin for 2 weeks and im gonna stop today. How long will the withdrawals last and what am i gonna feel. Is there anything i can do to ease the pain.

  15. I ran out of the Wellbutrin RX that I have been taking for 4 years. It is now waiting for me at the pharmacy, and I’m not sure whether or not to get it. It has been 5 days since I’ve had the med, and I’d love to get off of it. Do I stop? Get it and take a half dose?

  16. I have been taking Wellbutrin for abut 2 years and my doctor has slowly worked up to a 600 mg XL dose per day. About 5 days ago I submitted my new prescription and my insurance has refused to allow it to be filled. The pharmacy has insisted that they have faxed my doctor. My doctor’s office has insisted that they have not received a fax. So on Friday beginning of a long weekend I was assured by the doctor’s office that all paperwork was with the insurance company and it would take 24 hours to approve. Except that they are closed Sat, Sun and Monday (MLK, Jr. Day). If they approve it the earliest fill date is Tuesday. So I have been looking at withdrawal symptoms and my husband has been watching me for those symptoms. Except that I have not had any so far. I am a little more sleepy than I normally am but I have been keeping myself from taking naps. By Tuesday I will have been without meds for 7 days. I feel like if I successfully make it that far without symptoms that I will not go back on it.

  17. I have been on bupropion Sr 150mg x2 and trazodone 100 mg x1 for 15+ years. My hearing, constant air rushing sound, has continually gotten worse until my hearing is extremely poor. Also my memory is affected, word recall, In reading uncommon side effects for both of these are listed. I would like to go off these and see if my hearing in particular can be improved. Can you recommend a a schedule for decreasing the dosage safely until it is stopped? I may need to switch to different meds.

  18. I’ve been all over the internet reading as much as possible about WB withdrawals since I started in early October and trying to find comments and articles that are meaningful with good advice and that is safe. Remember THE most important thing — you are taking a drug that mimics brain function and when you stop taking it, your brain is confused, hurting and not able to function like it did on the medication. You are basically starving your brain of the chemicals it was dependent upon for concentration, focus, anxiety, depression. This is why you should never stop cold turkey — no matter what other people are saying.

    Look up safe ways for gradual withdrawal and consult with a doctor or a pharmacist on how to do this. It depends on the kind of WB you were prescribed and being prescribed smaller doses and even cutting pills. But some of the brands (SR, XL) can’t be cut for example. It is a slow and careful process. You take less and less in weekly or monthly increments and take care of the symptoms along the way. It can be done safely, and to rush or just want to be off of the meds just because is not an intelligent way to view the process. You wouldn’t just stop a high blood pressure medication, for example. Or an antibiotic. Or anything. The longer you’re on it, the longer it will take for safe, gradual and gentle withdrawal.

    Yes, there will be side effects a long the way and I’ve experienced all of them listed. But you rest, eat well, breathe, go about your daily life and always check in with your doctor.

  19. Decided to post as an update to this blog…

    I quit Wellbutrin cold turkey when I found out I was pregnant and it is not safe to take during pregnancy. My doctor suggested a 3 day taper of skipping 1 pill every other day (150mg/day) so I figured I would be ok cold turkey as I have only been taking for 6 months. I’ve been off about 2 weeks now and the headaches are really intense and painful and last days. I have an incredibly stiff neck and muscle pains. Insomnia every night and nightmares every time I do actually sleep. Based on my experience so far I suggest a long tapper to avoid these withdrawal effects.

  20. Am currently 2weeks into cold turkey stoppage of Paxil 60 mg as and Wellbutrin XL 150 mg bid and dropped my methadone from 40 mg bid to 30 mg bid. Don’t think I have ever been so sick, debilitated and hurting so badly. I’ve done this without asking my Rheumatologist for help, or permission. This has to be the most STUPID thing I have ever done. There are times I’m pretty sure I won’t survive this. NOT from suicide, just from the debilitation. I’ve been on this pyramid of meds(and so many more) for 15 yrs. am fairly sure there’s not much hope, but my faith is stronger than ever,so…… maybe.

  21. *Male, 35yrs, 6ft, Starting weight, 170lbs,
    *took 450mg SR, for years, but drank almost every day out of cravings and put on 45lbs in 5 months.
    *Self medicated to above the recommended dose of 600mg SR and my cravings went away. (and i saved $100’s a month on alcohol).
    *weight back down to 195lb, but not for long…
    *No seizures or any noticeable side effects taking 600mg other than my Dr wouldn’t prescribe that amount bc it was above the threshold.
    *Dropped back to 450mg and I am back in a deep depression. (quit my job, lost my home and belongings, verge of bankruptcy, and sleeping on a friends couch now)
    Weight at 239 lbs, and all i think about is death.
    quitting cold turkey sounds like my best choice.
    Welburtrin seems like it is freezing and destroying my life.
    Feels like my body breaks down the med faster than others.

    Best Regards.

  22. Hi Amanda,
    When I stopped taking Wellbutrin (also just stopped, per Dr’s advice) I was REALLY tired for about 6 weeks. No amount of sleep could help with the exhaustion. After about 6 weeks I started gaining energy and feeling more like myself. I don’t know if anything you can take in place- sorry =(
    Do know that your symptoms will pass and you won’t feel like this forever. Try to spend time with friends/family, whatever. I found it help just to get out of the house (even going to a move by myself). My exercise decreased from high intensity to simple walking- but it was important to keep moving.

  23. I have been taking Wellbutrin 150 for 2 years now.
    I live in a middle eastern country and they have stopped importing it.
    What is the best way to cope with the withdrawal?
    Is there another drug that I can take?
    I asked my doctor and he said just stop.
    I am already having mood swings and other symptoms.

  24. Two months ago I stopped taking Wellbutrin 350 cold turkey. I had convulsions like systems for three hours on the plane returning to the States. . Since that time I have had repeated convulsions like systems often . Have I done permanent damage to my brain with these seizure like systems; ? I never lost consciousness during the seizures. I have difficulty remember and doing math.

  25. I was on 300 mg of wellbrutin several weeks with prozac. Dr told me to go off cold of wellbrutrin and upd my prozac to 60 mg. Withdrawals? If any. How long if so.

  26. How long will the headache last after cold turkey off Wellbutrin I’ve been on Wellbutrin for 5 years and I just quit taking it

  27. I’m pregnant and would like to know if stopping suddenly would harm me… And is this a drug that can harm my baby… I’m seven weeks pregnant

  28. I took the Wellbutrin HCL100 mg four 2 day, and it made me too where I can see anything out of my left eye. Now I have headache and my heart feels like it gonna jump out of my skin. so I stopped talking it so now I’m having to go to the eye doctor to get a check up.i had a allergic reaction to the medicine!!!

  29. I have been taking wellbutrin 75 mg for 4 days. I can’t stand the severe headaches. I want to stop taking it. Can I just stop or do I need to wean myself off of it. I am unable to reach my Dr as she is away.

  30. Hello everyone! I have been reading comments for about 30 minutes and I have a lot to add! I recently stopped taking wellbutrin about six weeks ago! Within the first 72 hours I experienced dizziness, fatigue and anxiety! Within the second week I started experiencing worse dizziness, extreme hot flashes and sweating, the inability to deal with heat! The withdrawals are horrible from this drug! I was only taking 75 mg once a day for a little over a year and would never do this again! I don’t know how much longer the withdrawals will last but I cannot wait for it all to be over! I am now entering week six of withdrawal symptoms and I now also experience insomnia! For a period of about two weeks I experienced emotional highs and lows that seemed a little extreme! I am tired and sometimes lack energy to get through the day, I typically will take at least one nap a day! I know this too shall pass and I will keep moving forward and pray that this will not last much longer! Has anyone else experienced any of the side effects I have mentioned?? Sidenote, I am also diabetic and now my body is very sensitive to when my glucose levels are high or low!

  31. What is the best way to taper off of Wellbutrin? If you if you decrease the dose how long should you take the Lesser dose before decreasing again?

    1. Hi Kimberly. I suggest that you consult with your doctor to help you plan an individualized tapering schedule.

  32. I’ve been on wellbutrin for over 5 years, and am taking 450 mg per day. I have not been able to sleep and have hot, sweating spells, followed immediately with being cold. Is this a side effect? None of my health care providers are convinced this dose of wellbutrin is giving me any side effects…

  33. Was taking welbutrin as recommended by my Dr (150mg 1/dryly for 1 week then 150mg 2/daily after) noticed I was extremely dizzy and Dr recommended I stop cold turkey. I’ve only been on it for a little less than a month before I stopped. Now I’m feeling extremely nauseous and the dizziness has gotten much worse. Is this normal? How long will it last?

  34. I tried quitting Wellbutrin cold turkey a month and a half ago and it did NOT go well. I was originally prescribed Wellbutrin for depressive symptoms that I developed from my worsening generalized anxiety disorder two years ago. I did really well on the medication for almost two years, until about 2 months ago when I started seeing more of my anxiety symptoms returning. I discontinued the Wellbutrin because I didn’t see any point in taking a medication that wasn’t helping with my anxiety. What I didn’t count on was what would happen when I decided to discontinue Wellbutrin cold turkey. 4 days into my withdrawal I was experiencing suicidal ideation, insomnia and horrible brain zaps. This terrified me because I’ve never had suicidal thoughts before, so I naturally related it to the Wellbutrin withdrawal. I was finally able to consult with my physician and she instructed me to go back on the Wellbutrin and to stabilize before we talked about tapering me off of it. She changed my dosage from 75mg immediate release to 100mg sustained release with the understanding that I would be able to wean myself off of the sustained release easier than I would the immediate release. I took the medication everyday for a month in order to stabilize, and I just started my taper 3 days ago. So far I’ve felt a little lethargy and some slight depressive symptoms, but nothing compared to my experience when I quit cold turkey. I’m going to taper by reducing my intake from everyday to every other day for two weeks, then every three days for two weeks. Is this adequate or should I taper more slowly because of the adverse reaction that I had when I previously tried to taper off of the Wellbutrin? Any information, feedback or advice is appreciated! Thanks!

  35. I have moved about 6 hours from my physician. I have bee taking bupropion Hal xl 300 mg for a few years. I lost my job of 43 years 12-16. My husband passed 3-17. I have not been able to go back to my dr. My dr will no longer fill the prescription. I have been out for about a week and half to 2 weeks. I am extremely lethargic. And can barely get up. Could this be a side effect and if so how long should this last and should I go to urgent care?

  36. I stopped using Wellbutrin, it’s been at least two weeks at least. I noticed I am smoking twice as many cigs., eating more, not sleeping at all, and sweating a lot. Are these side effects and how long do they last.

  37. I was on Bupropion for depression and took it for 8 days. I stopped taking it because I thought it was causing me nightmares almost everynight. I slept good for 2 days but on the third night I had a bad dream. Something woke me up to see a large spider clinging down by the wall of my bed. I also have sleep apnea. I wake up so scared at least 3 -4 times. So I do not know what is causing me to have bad dreams.. As far as i can remember I had them once in a while, and it got worse as soon I started taking bupropion

  38. I’m taking Wellbutrin for weight loss. I want to discontinue as it’s affecting my complexion. I’ve been on it about 6 weeks. Can I just stop it do I need to wean myself off the drug?

  39. Hello,
    My Dr said that you can’t taper off Wellbutrin, that you just stop taking it. She said something about it being a timed release, so there’s no reducing the dosage amounts (to be honest, I’m not sure quite what that means). I stopped taking Wellbutrin 2 weeks ago and am so fatigued I can barely get through the day– I find myself unable to think clearly, and am struggling with remembering what words to say (and sometimes, what I was talking about in the moment).

  40. I was using Wellbutrin 300 mg, Efexor 150 mg and Epitec 50 mg ( all of them for mayor depression) for several years now. Now my doctor put me on Exsira 50 mg, the main reason, — I get depressed for a few months now and he want me to be on not so high dose of antidepressants. ( I also want to wean from this high dose of antidepressants )
    I have a few questions, please help me, I’m so tired, and so unsure what to expect, what is happening with my mental health.?? How long will it take to wean from all this medication???
    1. First we start with Efexor —– I start taking it every second day, then it will be every third day, and then every fourth day, and so it will be until it will be one a week – and then I wil stop using it.
    2. Then I will start with Wellbutrin the same way.
    3. And then with Epitec the same way.
    So I will be weaning from this medication in THREE months !!
    Is this the best way to wean of this medication ??
    BUT every day I use 50 mg Exsira — so that I can get use to this antidepressant.
    Please answer me, Really this is a very bad time in my life !!
    I also use medication for High blood pressure: Pritor 40 mg, Ziak 10 mg, Lomanor 5 mg. Cholesterol – Vusor 5 mg.

    Please give me advice about the antidepressants, on the long term which of these medication can I use together.

    I will appreciate if you can tell me what will be the best combination. I know about Venlafaxine,Desvenlafaxine. About SSRI’s, SNRI, NDRI.

    Thank you so much !!

  41. I recently (3 ks. ago) went off Wellbutrin 150mg/2x per day and tapered off it. now that I have been completely off for about 3 weeks I am starting to feel some very pronounced side effects. I have been super tired like I can just lay down and sleep at any time and today thought I was going to fall asleep while driving just a 30 min. drive. I am also feeling intermittently anxious and like I have brain fog but that comes and goes. Today I feel dizzy for the first time and kind of sick. I also have been more hungry than usual. i have had some insomia and headaches that are strange feeling like very localized at the front and left side of my head. the other thing I have noticed is my motor skills such as I have really been dropping stuff and and feel my balance is off. I’m luckily not getting depressed except that I feel so crummy. I have been on Wellbutrin for several years( about 6 or more) for anxiety/panic disorder and depression. I really want to get off the medication as i want to see how I will feel without it and also I am concerned about the long-term effects. I really didn’t notice too many side effects until this 3rd week but I plan to stick it out, just wonder does anyone who has been on it for a long period like this know how long these effects last?

  42. Hi, I toke 150mg of Wellbutrin xl (generic) once a day for 3 months. I developed NASTY side effects and my Dr took me off of the med. 1 every other day for a week, last dose was May 5th. How long can the physical withdrawl last? Still have ringing in the ears, developed a rash on my face followed by REALLY dry skin on face and feet , and now I have some strange tingling sensation on my elbow and both feet ( not bad but I do notice it).

  43. I use to take welbutrin them recently started back on it. I started having bad reactions like increase in anxiety and my throat and toung started to swell I was on 300 xr . I had to quit emediatly, now I have constant headaches and brain fog. I was never addicted to this medication in fact I hate taking any type of medication. But its been 2 weeks I only took it for 2 weeks and the headaches are getting stronger, and the depression is the same as it was, which I figured it would be

  44. I have been on Wellbutrin XL 150 for about a month 1/2 I missed one dose and got sick..I want off it and my Dr won’t help. Please help me, how do I get off this crap and what helps with w/d effects? I have side effects that I font like and want off..

  45. I had taken Welbutrin 150mg Generic for 30 days. By the 2nd week I started to notice everything tasted off. By the 3rd week I had pretty much lost my sense of taste, but not sense of smell. So I powered thru to the 4th week & realized I can’t taste anything anymore & it was not improving my depression.
    My question is, I only took it for 30 days & have been off of it for 45 days and still have a lack of taste might even be Dysgeusia, as those are the symptoms. I have been to an ENT he said everything looked good to him.
    The reason I believe Welbutrin to be the problem is because its the only thing that was different in my life.
    I want to taste things normally again, the constant gross taste in my mouth & extra saliva at times and not enough at others is just horrible. Any constructive advice I truly appreciate.

    Thank you!

  46. I recently had to stop taking my welbutrin 300 mg. I have no insurance and can’t afford it now, nor any other antidepressant/antianxiety. I have been grumpy, irritable so bad I can’t stand myself!!!! Help

  47. How long for nausea to last. No reason ever for having been put on Wellbutrin. I do not smoke or been much depressed about anything.. What was the psychiatrist thinking /

  48. I had been on Wellbutrin for about a year and Prozac for several years. I stopped both cold turkey around the beginning of January. Over a period of weeks, I noticed my legs were becoming very weak. 3-4 weeks ago, I went to the doctor he put me back on Wellbutrin for the purpose of stopping side effects of the ‘irregular stride’ that I had read about. The goal is to eventually taper off of it completely. It has been 3-4 weeks being back on Wellbutrin and my legs are still very weak and shaky. Is this still likely from the Wellbutrin withdrawal?

  49. Hi,
    I was told by my Doc to stop Bupropion 150 XL recently cold turkey as he said it is a low dose and mild anti-depressant and I would not feel any withdrawal effects, which does not seem to be the case. I have stopped 8 days ago and I am feeling flu-ish, tired and a bit of a flat mood. Not depressed but just basically flat. I was told to stop buproprion as the Doc believed it was increasing my anxiety and since I stopped, I do feel less anxiety as compared to before. I am also taking cipralex 15mg, diazepam 2.5mg and 3.75 zopiclone to sleep so I am not sure if this combination is making me tired now that I have stopped the bupropion which I know is a stimulant.
    Can you give some thoughts on the withdrawal symptoms that I am experiencing and will it subside soon or am I at risk of it getting worse? The thought of it possibly getting worse in itself is probably making me a little anxious. Thanks.

  50. i”ve been wellbutrin for about 9 days and i want quit using it. my doctor is away and won’t be back until thursday. what should i do?

  51. I quit cold turkey after 5 months on Wellbutrin SR 200mg twice a day. I replaced the meds with high quality multivitamins and salmon fish oil. A strong cup of coffee in the morning and exercise 4-5 times a week. It’s crazy how mentally I thought I needed it and realized these were just feelings and they soon pass.

  52. Thank you for your discussion of bupropion withdrawal. I took the drug most of the time for 7 months and have been off it 30 days. I decreased the dose gradually. A week ago I started feeling very sad and have cried uncontrollably ever since. Any ideas how long this will last?

  53. Hello guys. I am very sorry to hear about your addictions. I know what it feels like. i have overcome my addiction through a natural way; using ayurveda.

  54. my daughter quit taking welbutrin a few days ago would it be ok to go back on them and try weening off slowly

  55. Been taking 150 mg for about 4 months. I want to stop because of the side effect of weakness in my legs. I am off balance and fear I am going to fall and break a bone. My doctor said to stop taking it but did not mention tapering off. I was not satisfied because he did not mention any withdrawal problems. I am not prepared to have a seizure (how common) and reoccurring depression. Any thoughts? I need a replacement for sure, but not sure what that would be. Mad because the drug worked except for the muscle weakness.

  56. I am 58 years old. I was prescribed 150 mg 1x day of Wellbutrin 2 years ago. It saved my life. The two side effects I had were Tinnitus and an affinity to have an emotional teary reaction to just about anything. I also have suffered from Vertigo since 2013 and the vertigo got worse since being on Wellbutrin and was recently hospitalized for a particularly bad bout. Two weeks ago I decided to go off of Wellbutrin. Cold turkey. My life circumstances that caused me to go on it in the first place are 100% better but the Tinnitus is so severe that I thought I’d give it a try. It’s been two weeks. The first week I literally had unbounded energy, no emotional upsets and didn’t need to sleep all that much. Second week…different story. Wake up anxious (I have anxiety meds, so I’m using that to help) and by midday I am dizzy and just have a heaviness in my eyes where I just want to go to sleep. Also feel like my heart is racing. The tinnitus is still severe. I feel that I’ve come this far I might as well stick it out.

  57. I have been on Wellbutrin for about 3 months. I am experiencing severe leg weakness and can hardly walk. So afraid I will fall and break a bone. My arm are weak also but not as bad. I am still feeling depressed but feel the drug is working. I am 70, 108 pounds female. Feeling I should get off this.

  58. Hello…I’m hoping to get a response….I had been on Paxil 40mg for 20 years and Lamictal for about 8. In October of 2016 my doctor took me off both Paxil and lamictal and put me on Welbutrin. (150mg. Once a day.) Since I had been on medication for so many years I wanted to get off everything. I’ve tapered off completely from the Welbutrin. I did the tapering slowly. It’s been about 4 weeks. The first two weeks I felt great! I was so happy to finally be free from meds. But the last 5 days everything changed. I’m so extremely depressed, I can barely function! I just don’t know what to do! Is t my brain getting used to no meds at all or am I going to feel like this for a long time? I can’t stand it. Would sure appreciate some input.

  59. Hello, I have been reading these comments for hours. I am so concerned for many of you, I wish I could find out if you’re doing better now. I hope so. For those of you feeling alone and hopeless – IT WILL GET BETTER. Believe that. Give it time.

    I am hoping that sharing my experience will help someone.

    I have been taking Bupropion extended release 150 mg for over 4 years. I’ve been taking Citalopram 40 mg for approx. 8 years. I have suffered from depression and anxiety my entire adult life, but medications have helped, so has counseling. A doctor suggested that I try Bupropion because it affects dopamine rather than serotonin. She thought it would help me with my goal of losing weight. When I started, 150 mg was going well, and then she wanted to increase it to 300 mg. When I did, severe depression came over me very quickly, within a day or two. It was strange; and we agreed that I should go back to 150. So I did, and I was fine again, and I’ve stayed on it ever since.
    I’ve been feeling for a while like being on the Buproprion has perhaps made me unmotivated in life, and perhaps overly “okay” with things that shouldn’t be okay. Like it’s numbed me a bit. So I wanted to stop. Plus my prescription ran out, Dr. wouldn’t refill it anymore, no insurance, etc… So I stopped taking it about 2 months ago. Cold turkey.
    Withdrawals are real. I am thankful I have not been depressed. (I am still on my Citalopram, and I don’t plan on quitting that.) After about a week, I felt incredibly tired. I could have slept for 16 hours a day easily, and sometimes I did. I feel like that lasted for at least a couple of weeks. I also experienced painful headaches, which I never really get otherwise. These were pretty much daily and felt like stabbing pain in the front/side of my head. Hunger may be another side effect I experienced, but I’m not 100% sure that’s related. I feel like I gained weight just from being so tired. I thought I was feeling better this week and then tonight I just started having a severe feeling of dizziness. I felt like I was going to fall over. I think it’s starting to subside now. I hope so…
    Anyway, based on what I’ve read, it sounds like I may be experiencing these withdrawal symptoms periodically for even a year. It worries me a bit, but I’d rather keep going at this point. It makes me think though that drug companies should do studies on withdrawals and be required to post that information, and healthcare providers should be required to inform us. I know that I am very guilty of just trusting what the Doctor says and not do any research on my own until there’s a problem.
    I was also surprised to read in one of the comments that Bupropion has been tied to Pancreatitis (although not very common).
    I wish you all the best, and thank you for sharing your stories as well!

  60. NICOLE: So sorry to hear you are feeling so poorly this morning. If you are sure the depression is not a delayed reaction to the Christmas season, it could very well be the Wellbutrin. In some cases people can have a “paradoxical” effect, or the med actually makes the symptom its trying to treat worse. This is also true with xanax if you stop taking it and restart. The problem with Wellbutrin is it a long lasting drug, and it’s hard to tell when in treatment if you have a symptom, if its a cause of it. For example. I had dropped from a mere 12.5 to 9mgs of the Wellbutrin, and was fine for 7 weeks, and then it messed with my menstrual cycle, gave me the partial seizures, and gave me the bacterial infection in my bladder that I only get after a Wellbutrin drop. So, yes, even as late as 2 months after a med change you can experience side effects of either an up dose or decrease.

  61. I have been taking Wellbutrin xr 300mg for about 2 months now. I feel that it has increased my energy and helped quite a bit in terms of increasing my mood. However, I woke up this morning with the most severe depression I have ever experienced in my life. I have been crying on and off all day and I actually contemplated suicide for a few hours. I was diagnosed with bipolar depression and anxiety over 10 years ago and I have never felt this horrible in my entire life. It’s been about 12 hours and my mood has not improved at all. I am not physically ill and do not have any health problems (apart from mental). Anyways, about 3 days ago I accidental forgot to take my daily dose of Wellbutrin but the past 2 days I resumed taking as usual and I took my dose this morning. Is it at all possible that I could be experiencing a delayed withdrawal response from the dose I missed several days ago? I know it sounds outlandish but I really cannot understand this extreme and sudden onset of this severe depressive state. Can the medication just suddenly be giving the opposite effect than intended? Just for reference, I also take about 3-4 mg of Xanax daily (I have for over 3 years) and also seroquel 25 mg to sleep. Can these suddenly be interfering with the effects of the Wellbutrin? I really don’t know what to think at this point and any input would be greatly appreciated.

  62. a few weeks but never completely went away. Now, a year later, they have increased greatly. My doctors are skeptical that I am still undergoing withdrawal, but there is no denying the symptoms. Have others experienced withdrawal lasting over a year?

  63. I stopped bupropion cold turkey ten days ago and other than some mild dizziness that was not altogether unpleasant, all I feel is relief. I was on 150 ml SR for 11 months and it made me feel tense, anxious, irritable, and so forgetful it was scary…but it helped me stop drinking so it was worth it at the time.

    After three days off I felt like myself again. Now at a week and a half, the medicine is entirely out of my system and I am still waiting for the withdrawal symptoms. Seems like I am the exception not the normal, but wanted to share that it’s not always awful if you feel like you need to get off the stuff.

    I do make it a priority to get outside and exercise every single day. So that is likely helping.

    Good luck and happy holidays:)

  64. I’ve been on Bupropion which is generic for Wellbutrin. I wanted to stop taking them but I have friend who was taking these meds and she lost a lot of weight and she said when she stopped taking them she gained so much weight. So my question is if that’s true. I have lost like 18 pounds will I gain them back plus more? Or is that false and is something people want to put blame on for gaining weight? I’ve been trying to do some research on it but it all comes back the same that women have lost weight and gained it all back when they stopped taking the medication. If this is true how so?

  65. I’ve been out of my wellspring for about 3 days. I’m never cold I have been freezing, cold chills, shortness of breath. Could this be withdraWl

  66. I have been on bupropion xl for 5 wks. 300 mg. All I have had are side effects, (nausea, dizziness and a lot of ringing in my ears) with no relief from my depression.
    I decided to go off. My Dr. says I can go off cold turkey, is that true or should I go down to 150 mgs. first.
    I have been off for one day and still have all these symptons, even a little more magnified. I would greatly appreciate your opinion.

  67. I went off of welbutrin 450 XL cold turkey. I am super tired and sleepy. I am not going to back to taking this medicine afoot so would detoxing help me feel better or do I just wait it out. Detoxing may not be an option is there a way to cope with these withdrawal symptoms.

  68. This is the worst thing you can ever take stay away from bupropion. I had uncontrollable shaking hallucinations no sex drive . I was only on it for 3 days and it had this effect on me . I think it is a terrible thing to put anyone on .i will self medicate. With Marijuana. The weed equal no side effect . You can kill me before i will ever think about introducing any anti depression drugs into my system. STAY AWAY FROM THIS IT IS A VERY BAD DRUG. I WILL NEVER USE ANYTHING LIKE IT EVER AGAIN.

  69. I was on wellbutrin for 4-mos to quit smoking. After the third month I started to get agitated, short temper, etc. My Dr. said since I was only on it a couple months it would be OK to go cold turney. Since then, 14-days ago, I have had a migraine every night. I cannot take imitrex for my migraine because you can only take 9 a month. Has migraines ever been an issues with anyone else so frequently?

  70. I decided to stop my citalopram and bupropion after a run of tough luck that was draining the bank account. It has been about ten days and I am finding focusing increasingly difficult as well as a lot of vertigo and an out of body feeling. At first I attributed to an ear infection/strep throat that I had two weeks ago. Agitation spikes have been happening. So I have two questions; first how much longer should this be happening. Second, are there any cost free resources for me to reach out to?


  71. Hello, patient here experiencing major negative withdrawl symptoms

    In particular, frightening, debilitating cognition and focus issues.
    Beyond fact that I am an otherwise intelligent person aware that I am losing my cognitive function, I am now experiencing vivid hallucinations, blurred vision, major balance issues, lack of coordination

    Taking this drug is singlehandedly the worst mistake I have ever made, because this simple pill has been more debilitating than being hit by an 80,000lb vehicle.

    I was on 200mg bupropion for appx 2mos, and started a tapering off schedule with my dr, but 4 days in I started having seizures and rather than take more and start over we have gone cold turkey.
    I’m sorry but as a rational person with no history of seizures, and a substance is causing them, i’m not going to keep taking it
    My doctor agreed and i have been going cold turkey. Withdrawl is violent and debilitating. I am an excellent driver with racing experience and can usually hold it together but the side effects hit so suddenly and so violently i must advise anyone stopping bupropion or having recently stopped it to stop driving and arrange alternate transportation

    I have treated my adhd symptoms successfully for years with ritalin (and recently had great success with vyvanse but my health plan doesnt cover it and I cant afford $300 copays).
    My new psych did not want to try dexadrine or vyvanse, since I felt like the ritalin was making me “snappy”/irritable I was trying to get the irritability and anxiety in check

    I have existing kidney damage (lost half a kidney due to emergency embolization of lh pole) and liver and general abdominal organ damage resulting from a motorcycle crash in 2012,

    We are halfway through week 3 since last dose.

    I understand that ADHD is an offlabel use for Bupropion, and has an extremely high incidence of negative interaction with ritalin, and is not advised for use in persons with liver damage. At the time I started taking it I was not aware of the negative interaction with ritalin, the offlabel nature of using bupropion for adhd or that my internal organ damage (on my charts… extensively was a factor.

    I am a non drinker and nonsmoker.

    I have been experiencing every single side effect listed for bupropion withdrawl – no more “partial complex seizures” with large chunks of time lost but tons of episodes of totally spacing out, imagine your thought process just kind of slows down to a crawl and drags at a snails pace for a few seconds and then jerk back into being mostly aware again as if I’d woken from dozing off.

    In the past week my balance issues have gotten so bad I can’t drive anymore and my cognition has been so bad that I havent been able to do my job as a writer in several weeks…

    I discontinued the bupropion because I felt like it was getting harder and harder to focus and I was nauseated all the time, and my ritalin felt like it had totally lost its effect, and has not been effective for weeks prior to stopping bupropion

    I need to know

    How long do the debilitating symptoms of SRI Discontinuation Syndrome continue to persist? How long is my balance and coordination going to stay screwed up?
    How much longer do I have to endure not being all there in my own head?

    I am not 100% on my a game but I am still with it enough right now to have written this and put together that my cognition and focus issues are specifically related to the fact my dopamine receptors are blocked, which I believe is the cause of this mental fog/haze and extremely difficulty with concentration.
    Coffee has almost no effect besides tasting good, and I enjoy drinking it, and excedrin migrane seems to be effective at preventing the migranes

    However the lack of focus and cognition- being able to think clearly enough to write – is an issue and I need to solve it NOW. Is there anything I can do about this in the short term besides just ride this out? I can’t work and my employer does not do paid medical leave so I need to function.

    In addition, the dramatic fatigue and extreme sleepiness and being exhausted despite tons of sleep, and again coffee doesnt help. I believe this and the random episodes of slowing down and spacing out have to do with the norepinephrine receptors being blocked as well

    going to the physician won’t resolve anything and going to the ER will resolve nothing and get my drivers license suspended for six months which will effectively put me out of work, too

    Beyond this my emotions are out of control, and I’m aware of it

    Is there anything I can do to shorten the duration and severity of the side effects?
    Is there anything I can do to get my cognition back to its full capabilities?

    I have been having vivid visual hallucinations (bright objects appear glowy or shiny, vision is blurry and splotchy) and been having extreme difficulty with thought processing today

    My clarity comes and goes at random kind of like a rollercoaster.
    It’s like all the worst parts of being drunk, the flu and a bad psychedelic trip all rolled into one.

    Feel tired, achey and fatigued and yet restless, jittery and uncomfortable sitting still

    Please help me

  72. I’ve been on Ibupropian xl (wellbutrin) for approx. 6 years 300mg. I’ve tried to get off this med several times but gain weight immediately. I’ve reduced my dosage to 150mg xl and it’s been 3 weeks, gained 5 lbs already. This is so discouraging. Has ANYONE successfully stopped this drug and eventually lost the weight gained caused from the withdrawal symptoms??????? PLease help me. I need motivation to get off this med!!!!

  73. I am amazed at all the wild tales about side effects of stopping or starting Welbutrin. I have been taking it for several years for major depression. There was a volatile period of side effects and adjusting when I began taking it, but otherwise it has been a miracle drug. I had been secretly battling major depression my entire adult life. I kept my feelings closely guarded, devising whatever coping and compensation strategies were necessary to hide my. In my mind it was not a “disability” or treatable “condition.” It was simply a shameful weakness, to be exploited by others. therefore it was a measure of defense and pride of pride and deI did not seek counsel, advise, or treatment of any kind from friends, family or doctors until symptoms became paralysingly debilitating with middle age. I am one of those types of people who keep my problems to myself.advice or help frm anyone kept my own counsel, covering up the symptomse. I was in pain all the time (especially back pain). I was tired all the time but could not sleep, I had no will or energy to do anything. both my physical and mental functioning capacity

    1. Hi Julie. They might be since each body reacts differently to quieting cold turkey. However, experts claim that gradually lowering the drug dosage is a safer way to quit the medication. So, speak with your doctor to help you create an individualized tapering schedule.

  74. I quit Wellbutrin 23 days ago cold turkey …. Now feeling really sick and sore throat. I also have been having anxiety attack and breathing issues which cause me to not want to fall asleep. Could I start taking it again?

  75. Hey ive been off wellbutrin for 4 or 5 months. I know it can take a while for your body to readjust but how long does it take for your body to re up your neropinephrine and not be deficient? I went off cold turkey and am experiencing symptoms of epinephrine deficiency like muscle loss and fatigue. It has gotten better though but still not normal.

  76. I just relocated to Fl .. from NY I had to see a Psychiatrist .. Ii was tasking 75mg of welbutrin once a day only ( the brand not generic) for 10 yrs .. He told me to stop .. I have . This is the second day .I am not feeling great.. He said there would be no problem… Please inform me if there is any danger discontinuing this medication..

  77. Tried wellbutrin out due to the lack of sexual side effects. I have taken AD’s to control my stress related outburst. Now retired and want off Wellbutrin because it causes anger. Three days off and have been a real asshole, will this effect go away. Was on prozac 20mg and it worked good except I still like sex. But not enough to ride for 45 min to try to finish the job. Going to try to cool out out for a couple more days and then may look to 10 mg prozac.

  78. I was prescribed this drug in the late nineties for ADD. It made my hearing eerily acute and in short made be crazy and suicidal. Sadly, I called the Nurseline on Easter Sunday and she told me to stop cold turkey. Withdrawal included severe anxiety followed by deep depression. Sadly, I have been depressed ever since. 🙁

  79. I ve been on Bupropion for 6 weeks. My psychiatrist said its ok to stop if i wish. What can i take
    to fight the side the effects of withdrawl? I really don twant to depend on taking drugs to control my life.

    1. Hi Lawrence. It is normal to feel some withdrawal symptoms after quitting Wellbutrin. Good thing is you’ve been on it for only 6 weeks, so you can expect symptoms to subside soon. One of the most commonly felt symptoms is body aches and pains that you can help by getting plenty of rest, drinking water, and taking some over-the-counter pain relief. Sometimes people will start a different SSRI or antidepressant medication to treat present depression. You can use other over-the-counter medications to treat different physical symptoms.

      Psychotherapy, is important in recovering from depression and avoiding recurrence. You can also use the help and support of a close friend or family member.

  80. I have been taking 300mg of buproprion for about 7 years and stopped cold turkey 4 weeks ago. I find I am ok without it however can easily become irritable in stressful situations. Now I don’t think that is uncommon given the stressors of daily life in America today. I find myself getting very sleepy go to sleep ? and then wake up few hours later sometimes with a headache….so I am accepting the withdrawal as a consequence and will continue to attempt my resolve to stay free of this medication and other medications’ if possible….If I just observe my behavior and thoughts I think I can live without Welbutrin…67 year old male grandpa….

  81. Hi I’m 22 years old and I was on 300 milligrams of Wellbutrin Xl about 2 weeks ago I stopped cold turkey the other day I was at my mother-in-law’s house and felt very weak tunnel vision kind of feeling well and purple lips and wanted to sleep could this be a result of coming off like that

  82. I have been taking brupropian 300 (time release) and brupropian 75 (not time release) for many months.
    My Psychiatrist has just taken me off the 75 mg dose. I have terrible sadness/depression but then I have had this (complex PTSD) since I was a teenager. I am now 66. I have been in therapy for 21 years and Drs have tried everything. Nothing has ever worked. My Dr wants me to try other methods than only meds. She is highly acclaimed and very professional. Will I suffer with withdrawal? I cannot take SSRIs.

  83. If taken Wellbutrin for many years and have been on the low dose XL for two months. I stopped completely over a week ago and I’m exhausted I think I have a little anxiety, too. I wonder if I should start taking a pill every other day to ease the withdrawal. Originally took it to ease symptoms of menopause but that’s long over. Also, are leg cramps an issue?

  84. Was forced to Cold Turkey off of Buproprion 22 days ago due to severe side effect. Have been having severe anxiety since then. Dr prescribed clonazepam but it only takes the edge off. I’ve been pretty much house bound since quitting. I have other sypmtoms too, crying, mood swings, gastrointestinal issues and I’m hypersensitive to sound, light, movement, etc. all of which make the anxiety worse.

    Any idea on how long all of this will last? Reinstating and tapering is not an option due to the side effect. Also, any suggestions on things to help besides clonazepam?

    Thanks for any thoughts and/or advice.

  85. Due to a mix up attl pharmacist, I’ve been off welbutrin for 2 weeks. Not related is I caught the flu and now bronchopneumonia. Flu and lungs are getting better, but I am getting more dizzy and lowered coordination. Could this be withdrawal from welbutrin?

    1. Hi Geovanelli. It seem to me that you’re experiencing Wellbutrin withdrawal. I suggest you speak with a pharmacist to recommend some over-the-counter medications to ease withdrawal symptoms.

  86. I started 75 mg bupropion the evening of 5/6/16, from a neurologist for parasthesia & depression. She said I should stop Zoloft immediately & start the bupropion, the day she prescribed it. My pain is not relieved & now I’m taking 600 mg of gabapentin every 5-6 hrs for nerve pain, which the increased dosage of gabapentin is not helping at all. Was told I need to stop the bupropion @ night & only take it first thing in the morning. Why? It’s not helping my pain & making the depression worse. Crying daily bc I’m frustrated that I can’t escape the pain. Really wanna stop taking the bupropion. Not an addict & I’m taking it in the morning around 9-10 & 8 hrs later as suggested by the pharmacist. I HATE THIS MEDICATION! I’m having side effects worse than I did from Prozac. Help! I’m miserable. How can I wean myself off of this?

  87. Oh ya! Another side effect while on the drug was constipation. Also blurred vision. A drug that does this to our bodies cannot be good. I’m hoping that after a few months it will be cleared from my brain and body and I will lose my extra weight naturally. I do have to give it props for helping me quit smoking though. Five months smoke free!

  88. I started bupropion xl 300 mg in September to help stop smoking. It worked well! I noticed by the end of October that I had lost about 10-15 pounds, and I was extatic! However, I also noticed my hair thinning and some really bad cystic acne. So in November and December I went off and back on the drug a couple of times. Off to get my skin and hair healthy again. Then back on because I didn’t want to stop losing weight. Finally at the end of December I decided to stop because in addition to the hair and skin issues, I was becoming very agitated and angry. I’ve been completely off the drug for one month exactly today, and I have gained every single pound back. I’m so tempted to get back on simply for the weight loss, but I’m still trying to clear my skin back up. I’m about 75% back to normal skin. I also notice my hair is better. The worst (and only for me) withdrawal symptom is weight gain. The side effects while on the drug were dry eyes, terrible skin, dry, brittle, thinking hair, anger and agitation. I sure hate gaining weight though. I wish I would never have taken it to be honest. Then I wouldn’t know how well it is with weight loss and be tempted to ruin the rest of my body to lose weight with it again. Ugh!

  89. Hi guys. I’m just a little nervous and I need your advice. Im 23 years old. I’ve been taking Bupropn HCL 150MG XL since Nov. 23, 2015. Its been almost 8 weeks since I’ve been on it. I was curious as to how i would go about getting off of this medication. I take it for depression and S.A.D. I just recently moved and I had to switch Medication Management/Psychiatrists. I have an appointment tomorrow with the new therapist, and I’m worried if they will still be able to prescribe me this. What will happen if they don’t prescribe me it? I’m worried that I will have withdrawal symptoms and I’m scared. Will I go through a deep depression like before? Suicidal thoughts? Headaches? I know I seem to be rambling on but I’m just worried. I appreciate anyone who reads this, and responds. xo

  90. I had been on this for about 3 months. mad me emotionally unstable and when I went off of it I had severe anxiety and flu like symptoms. .actually thought I was going to die. ..whatever you do do not go cold turkey. .it’s horrible.

  91. I lowered my dose to 150 mg, from 300 mg. I am trying to get off of all medications I’m on. Also on 80 mg prozac. and .5 lorazapan to sleep at night.
    I’m first trying to ween off the welbutrin .. i’m feeling those symptoms above (i’m on probably week 2 after lowering), feel super depressed and crying a lot. zero desire to workout (usually workout all the time and love to)…been laying on the couch nearly all this weekend and last and not leaving the house. Is this normal? should/can I do anything to help this? It’s really making me consider going back to 300 mg. I am not one that does well with putting on weight either (body image issues). is this all normal even though I’m just lowering the dose and not doing this cold turkey? Many thanks.

  92. I quit Wellbutrin 300 mg XL after 4 months due to unrelenting somulence and a feeling of apathy. Dr said this was highly unusual reaction. Is there evidence of others suffering such side effects. I went from 300 mg to 150 mg for 2 weeks with no change in side effects and now have been completely off for 2 weeks. I continue to take 25 mugs of Cipralex. I believe I am incurring a number of the WD symptoms you have indicating. After about 12 days I suddenly began to incur a depressed feeling which would begin late morning and subside by late afternoon. The feeling felt like sadness but was not accompanied by hopelessness etc. Nevertheless it has been very unpleasant and disconcerting. Is this typical of the transient rebound depression you are referring to. What studies have been done that indicate rebound depression as a symptom of withdrawal from Wellbutrin.

  93. I moved to a new state. Before I knew it I was out of my anti depressant. I did not have a new doctor as of yet either. It has been about 2 weeks since I quit cold turkey. Not out of want but because I just ran out and I am now on a different PPO plan. I was super tire the first week, and this week, experiencing dizziness…. and a light fog will come in and out of my head all day. I am not sleeping well. So I am drinking tea at night to help with that. Am I going to die? Is something going to happen to me? I am super scared right now.

  94. Well after 12 years of being on Effexor and then 5 years on Wellbutron ~ I decided to go went off it without my doctors knowledge….which I guess I shouldn’t have. It’s been a few weeks of extreme tiredness, brain fog and 10 pound weight gain and I do not feeling well at all in spite of trying the 5~HTP and Turmeric etc…. BUT I’m not depressed at all and I have stopped my life long episodes of crying! Now I’m at a crossroad of wanting to feel better again and lose that 10 pounds and not be in such a brain fog….and off pharmaceuticals and into a natural source of whatever I need!

  95. Have been on the lowest dose of Wellbutrin for 2 years – after losing 50 lbs and getting into the greatest shape ever and having a hyper sex drive – all I wanted to do is have sex every day and work out at the gym lots but the drug started to make me very irritable and dislike almost everything. I was walking around almost crazy in negative thought. I would argue almost anything. I discontinued the 100 mg per day – without any at all withdraw – now after 3 weeks I have days where my anxiety is high and have extra sensitive emotional thoughts. I seem to sleep well and have energy to act my normal day.
    I tried Cymbalta – was amazing – no sex drive at all but – mood was amazing , slept well – but bad side effect of very sore hurting joints made me stop as I could hardly bend my knees.
    I am now looking for something new or will try Wellbutin again.

  96. My doctor reduced my dose of bupropion from 300 mg XL once daily to 200 mg SR once daily. This dose reduction was done because I was experiencing a lot of side effects which I was managing until my period stopped, which is when my doctor got concerned. Will I experience withdrawal of any type from this dose reduction? I thought I would be taking the SR formulations twice daily to keep my blood level up to 200 mg but my doctor only has me taking one in am. I’m really afraid my depression symptoms will return. Should I be worried?

    Lastly, my doctor chose bupropion because of its pain management properties. I’ve only been on the 200 mg dose for one day, but I’d swear my pain is worse. Any thoughts on this?


  98. I was taking Cymbalta 60 mg and Wellbutrin 450 mg for over a year. Then I dropped 150 mg of Wellbutrin because it didn’t appear to be working. A month later I was taking Cymbalta 30mg (decrease), pristiq 50mg, no Wellbutrin. I am supposed to do this for 2 weeks and drop the Cymbalta and take pristiq 100mg. Right now while on 50 mg Cymbalta, 50 mg pristiq and one week off Wellbutrin, I am really tired, sleeping upwards of 10-11 hrs a day, have moderate diarrhea (using Imodium) and don’t give a flip about anything. The loose bowels have been on and off for a month and the excess sleeping about 3 weeks. Hopefully the pristiq 100mg will solve the depression. I am really concerned about the sleep and diarrhea and wonder if this might be from coming off Wellbutrin and lowered Cymbalta. Is this possible?

  99. Am I having rebound symptoms? I tapered off Wellbutrin via the dr. I was on 300sr for only 4 weeks. I had to come off due to no insurance coverage and won’t have new insurance until Nov 1st of this yr. dr had me go from 300 to 150 then taper off for two weeks doing an every other day pill. That was four weeks ago. Since then I have had ringing in ears so bad I can’t sleep, brain zapping 24/7, motor function unsteady, loss of memory, tiredness, irritable, muscle pain, heartburn out of this world. I feel like I’m losing my mind. I had to go to urgent care two weeks ago due to loss of memory and this horrible zapping and ringing in my head. The dr checked to make sure I didn’t have a stroke and when I was cleared he gave me scrip for steroids. I finished my steroids 4 days ago but still having horrible ringing and zaps. Is this just rebound or is this something else and if it’s rebound please how long will this last? I’m about to lose it.

    Thank ou in advanced

  100. I’ve been experiencing simple partial-phsyic seizures during the ending phase of my Wellbutrin withdrawal. My original dose was 300mg. Originally cut in half to 150 and had severe symptoms day 9. Stayed at that level for a month and then tapers down 25mgs every 2-3 weeks. Since getting down to below 75 mg’s the seizures started. I’ve been cutting pils in half and quarters and now 8ths to low the dose gradually. I had been at around 28mgs for 6 weeks and was doing better. I dropped down to about 18mgs and within a week had the symptoms back again for 5 days. After being at that level for 3 weeks, I decreased to about 12.5 mgs, or an 8th of a 100mg pill daily. Within 1 week of that drop severe symptoms including the seizures were back. Why are the symptoms geting worse even though the mg drop each time is less? Is my body just that sensitive to the med that merely dropping from 28mgs to 12.5mgs over the course of 4 weeks can do this?

  101. My som was I’m 2 tablets a day’ he has weaned himself down to 1 a day. He is experiencing extreme tiredness,can hardly stay this a withdrawal sympton

  102. It’s’ been 2 weeks when I last took bupropion for weight loss. I have to do a physical test and drug test for a new job. Should I tell them I use to take bupropion? Will it come out as a positive for opioids or any other drugs? Thank you for your help.

  103. I stopped Bupropion because Kaiser messed up and it was not sent out and then I went out of town. My first symptoms were a out of body feeling mostly my head felt like I couldn’t wake up. That lasted about 5 days. Anxiety started, butterflies at first then crawling skin and not being able to sit still. Went to urgent care and they didn’t make the association to the bupropion. ( I had no idea it was withdrawal). They gave me a mild tranquil. I only took 1 a day. I was unable to talk in full sentences and it irritated me to hear people talking. I stayed in bed sleeping and lost track of time. Went to Kaiser and they gave me my prescription. It has taken 3 days on medication to be able to return somewhat to normal. I have had to fight some depression.

  104. I have been on 150mg of bupropion for a month, and feel worse since starting to take it. I have nightmares, am more depressed and feel like I need to stop taking it. How should I do that. My Dr is no help and is unavailable most of the time. Please help

  105. I have been taking 300mg of wellbutrin for good six years went off cold turkey can’t afford it no longer I have vivid dreams hard to sleep lots of muscle pain I am in in so much pain can’t hardly move I feel horrible. How long will this last and is there something I can do to help me thru this?

  106. I have just recently stopped all pain meds for my RA 5 weeks ago and Plaquenil and Gabapentin. I have had severe withdrawals lasting 4 weeks and I’m still not 100%, still achey and very fatigued. I have 2 more drugs to go before off everything! My rheumy had me loaded up on pharmaceuticals – I was an idiot for trusting her – she put me on Wellbutrin and I wasn’t depressed! Ok so now I have to taper off Lorazapam 0.5 mg and Wellbutrin XL 150 mg 2x/day. My primary dr said to take 150 mg for a week then every 2 days for a week then come off and said to cut my Lorazapam in half take for 2 or 3 weeks them cut the half in half and take for 2 weeks them come off and I could do these two drugs together! Am I nuts for trying to wean off these two drugs at the same time or should I just get it over with? Thanks so much.

  107. I was just wondering if the withdrawals involve anything to do with a pancreas dysfunction of any kind?? I’ve been off wellbutrin since May 2015 Cold Turkey And my dos Was 100 MG SR. and this Is what I’m experiencing

    1. Hi Amy. One of the possible side effect of Wellbutrin use is pancreatitis. It is listed along with many other side effects.

  108. I have been on 400mg wellbutrin sr for 18 years. Yes, 18. None of the ssri drugs worked for me. Wellbutrin is different. It is in a class by itself. Only thing that worked for my severe depression. I used to smoke. I was not looking to quit. Lo and behold 10 years in and I was and still am smoke-free. I cannot stand the smell of cigarettes. Wild. I am also diabetic. My depression is organic (as opposed to situational). Would I go off of my insulin? No. I also have hypothyroidism. Would I go off my synthroid? No. And I would not go off my wellbutrin either. No. Why everyone is so adamant about getting off their antidepressants is beyond me! Read your posts. Why do you want to feel depressed and worried again? Physically ill!? Some people will have to be on meds for the rest of their lives. Found one that works? Well, your one of the lucky ones. Please think before going off of your medication. It can be a matter of life and death just as much as me going off my insulin.

  109. I have been on paxil for 5 years and just ween off of it. I have now been on wellbutrin for 7 days. I feel worse then ever I just want to go off all of it.. can I stop cold turkey of this a short period of time.

  110. I have tapered off Wellbutrin after 5+ years and have stopped totally when my doctor told me I could have a seizure if I had more than 1 drink a week. So, in the last two weeks, have had crying spells, headaches and hearing electric zaps in my brain. Are the electrical sounds normal in med withdrawal? I quit totally 2 weeks ago.

  111. Is it possible to havd a change in body temperate. I do not sleep at night at offen hot then cold white laying in bed for hours. Im been of wellbuttin for a month and a half. My insurance has mabe me change Dr. Its been a huge hassle. But i will see her the.

  112. I have been on bupropion for about 3-4 weeks and I did not like the way it made me feel so I started to taper off of it by cutting it into a 3rd, then half, then a quarter. I have recently stopped taking it 3 days ago. Am I at any risk for seizure? It its not genetic in my family and I have never had any before.

  113. Question about bupropion withdrawel. I am taking 75 mg of bupropion once every other day. It is not extended release. Will I have withdrawel if I stop altogether? Have I been having withdrawel every other day? Thank you so much. I just went to a psychiatrist and she could not answer this question.

  114. I’m trying to get off Wellbutrin. I was at 450 milligrams. I tapered off 150 milligrams at a time. I’ve been on this dose for 8 months. I tapered off my final dose last week and I’m having now having body aches, I am sore, and still very tired. My mind is feeling clear but overwhelmed and exhausted. How long will this continue ?

    1. Hi Elizabeth. Wellbutring withdrawal symptoms usually last for several weeks, but get low on intensity after 2 weeks have passed. You can go to the local pharmacy and ask the pharmacist about over-the-counter medications that can help you treat the exact withdrawal symptoms you are experiencing.

  115. after taking the genetic wellbutrin xl for approx 3 weeks stopped cold turkey per Dr orders. First day of not taking it & had anxiety & feel like coming down from an ecstacy high. Is this normal?

  116. Hi There,
    After using Bupropion 150mg once a day for 2 years I developed food triggered classic migraine headaches.
    My migraines developed into chronic daily headaches, triggered by almost any kind of food and is only relieved by long term released tryptans (naratriptan 2.5mg). It seems my BP which should be 120 x 80 mmHg is now constantly lowered to 80 x 60 mmHg.
    I’ve visited many doctors specialized in migraines and tried a series of preventive drugs. Unfortunately nothing worked. I am currently out of hope and even my health is deteriorating due to the daily use of tryptans.

  117. I have been post-op from spinal fusion surgery for 5 weeks. I have been taking a combination of Bupropion XL 300mg, Duloxetine DR 60mg for depression and Propranolol 40mg for hypertension.

    I have been taking these medications for the last 7 or 8 years and after surgery I had skipped some doses. My Blood pressure was very low with an avg. of 110/56 so I thought I’d stop the propranolol for a while. I have been off all 3 of the medications for about 10 days, or a little more now, and during that time have had a foggy feeling in my head and general light headed feeling. I have felt very little depression, but a lack of energy. I also have nightmares, usually of some kind of forced drug use like having been tied down and injected with something. My bed is usually soaking wet sometime during the night as well. I don’t want to take any of these medications any more because I want to feel as if I am through with the dependance of them. Other than the above symptoms, I think I’m doing well, coping with these side affects. My question is how long do you think they will last and am I subjecting myself to harm by doing this. I am monitoring my blood pressure each day and it has gradually returned to a more normal reading of avg. 115/65-70, I believe in the long run I will be much healthier off these meds and want to continue to stop using them.

  118. Hello. I have been on Wellbutrin for nearly 8 weeks now. I missed my morning dose today(usually between 8-9) and by 3 I was in full fledge withdrawl. I absolutely was scared for my life at one point. Luckily I was able to get home within 30 min of onset sumptoms and take my dose. In about 30 min the pain in my stomach and chest began to subside. It has been 3 hrs since I took this. My stomach still hurts some, I still have the diarrhea and feel just terrible. Any idea on when I might feel better?

  119. I’ve only been on Wellbutrin for a month and was very concerned about the weight I gained while being on it. I gained 25 lbs in only a month and it wasn’t making me feel good about myself at all. My doctor told me to stop and see how it goes…I’m nervous with what withdrawal symptoms i’ll get…I haven’t been on them long…is there a chance that I’ll get depressed again when my doctor said he thinks its only seasonal depression?

  120. hello, my question is on unintentional withdraw from wellbutrin xl 300mg, 10 days prior i had gotten a cold, turned into excruciatingly painful sore throat, and that was the time iwasnt able to take my medications, my cold turned into obstructive chronic bronchitis with exasperation of asthma, and i had the worst symptoms with it, ruled out the flu, strep throat and mono, there is so little information on symptoms from side effects from stopping wellbutrin cold turkey because of a cold or illness, i had rapid unorganized thoughts, confusion, fatigue, could eat or drink, so what im asking is when this occurs again, what is our suggestion?

  121. I’ve been off Welbutrin 150xl for about 3 months. Yay. It worked better than any antidepressant ever did. All withdrawal symptoms gone. Working on losing weight I gained from not taking it anymore. The hardest part was it giving up and not taking it again. What’s even harder is finding a medication that can help me with depression and my anxiety. Back to the drawing board. This is the most difficult disease to find the right meds never giving up. Now I’m praying that this time I find the right medicine for me this has been a big struggle for me. Brand name with insurance cost $177 a month. What average American can afford that a month. Again generics don’t work I’ve tried 3 so far and they all hit my bloodstream too fast and I end up feeling like I’m on bad drugs and having a heart attack. I look forward to the day when I don’t have to be told to take generics for my anxiety and depression they don’t work for me. One day our medical insurance and medical Pyschiatrist will help us stay on brand name Meds. Welbutrin XL was the only drug I had success with for over 10 years. Now it’s back to the drawing board. Praying for me and all of you who struggle with mental illnesses. Never,Ever Give Up. Quote from Jimmy V.

  122. I have a question regarding long term side effects concerning Wellbutrin. I took 150mg of XL for the better part of 5 years. I quit 3 months ago and experienced 10 lbs of weight gain (lost 5 of that now) and some digestive issues but no longer feel what I think is depressed. My worry is related to whether wellbutrin causes long term altering of brain chemicals and if so, whether that will fade as well? Before wellbutrin, and even for the first year or so that I took it for mild depression, I felt much sharper/quick witted, assertive and more passion than I do now. For the last year at least and since I’ve stopped, however, I’ve felt only what I can describe as somewhat robotic, less confident and definitely not as sharp. Does anyone have information about the long term effects?

  123. Hello there. I am writing this for some relief and to try and normalize what someone else is going through and may benefit from my post.

    I started to take wellbutrin back in late October. I was taking it for ADD and the psychiatrist prescribed it to help stabilize my mood. I basically told him that I was having difficulties expressing my emotions and had some depressiona and anxiety. I had one panic attack while working at a very demanding work place. My bosss thought it would be beneficial for me to take medications for a bit to focus on my duties. I was hesitant and was not really sold on the idea of taking medications for ADD; especially taking medications for stabilizing moods.

    I took the medication back in early November for a month and a half. I believe I stopped taking them on the 23rd of December of 2014. I was feeling okay until after the first week of january. It was very subtle and not too much except for muscle spasms and twitching while I am trying to sleep. I also had a weird dream one night where I was laughing hysterically and woke up laughing. That is when it all went down hill. I started to clam up. I started having ringing in one ear (right) and a swooshing sound (in left) ear. Now the left ear is in beat with my heartbeats pulse.

    I have a huge sense of fear when I am on the freeway. I have had panic attacks while on the freeway. I get chills still; I am continuing to have serious insomnia. I have a fear of sounds and I have to investigate sounds to make sure that I am not going crazy. I am still twitching and I am in serious anguish mentally. I have good days and I have some bad days.

    Prior to taking the medications, I have never felt this way before. I am going to have a Dr. check out my tinnitus and hopefully they will not want to prescribe any more psych medications. I just want to be normal again.

    Anyway, I hope that this will help someone out there and know that you are not alone. I am continuing to struggle on a daily basis, but I know that the struggle with only make me a stronger person.


  124. Does wellbutrin cause you to gain weigh? Please help I have gained 25 pounds in 5 months.I can,t bear to be this fat! 5ft.3 198 pounds.

  125. Hi Erin. If you’ve been taking it for a while now, you’ll go through withdrawal if you don’t take your doses. In the article above you can read how the symptoms will be occurring. Usually these symptoms will resolve within a few days, and they are usually not severe.

  126. I came off Wellbutrin alone now it’s been 2 or 3weeks.
    I got worrisome headaches on 1 occasion. And big tiredness,needing to sleep a lot.That’s all so far.But I’m going to see about weaning myself off it , professionally through a D.R.after that 1 time scarey headache.,I don’t want to take a chance .

  127. Tried to take myself off wellbutrin & had horrible experience…… whole body swelled……hands, feet, fingers….everything…it was very uncomfortable..the agitation & mood swings were beyond belief. I gave up & have not tried to get off it again…..I am scared to death to try it. If anyone has a suggestion, please let me know. I am on celexa also & would like to get off both of them. I feel like I am trapped in a cage with no way out.

  128. Hi Ivana. Could you please give your thoughts to Christine and me who are both concerned with how long our weight gain after stopping Wellbutrin will last? Thank you!

  129. I’ve been tapered off slowly and am now on day 6 of totally being off of Welbutin. It’s taken me months to taper off. Brain fog, leg cramps, headaches and ear ringing are subsiding. My taper started by 150 every other day for a week. Then 150 XL every 2 days for 3 weeks , then 1 150 XL every 3 days for two weeks and now I’m totally off welbutrin 150xl. It worked well for me for many years. Then I started having severe intolerances to RX. Anxiety, agitation, tetinitus was horrible. I’ve now had a DNA test to see what my body can process and tolerate before I go on another antidepressant. Luckily, my depression isn’t bad. Probably, cause I’m so grateful to be done with all the side effects of withdrawal. By the way I was on this drug for over 10 years. Work with your psychologist and listen to your body too. I had to up my tapering off quite a few times. Be gentle with yourself and know you aren’t alone. Depression and mental illnesses suck and kill you like any other life threatening diseases. Trudging the road to happy destiny. One day, one minute at a time. 🙂

  130. Hi Marcia. Because of Wellbutrin’s long half-life and slow rate of absorption, it’s possible that the medication could remain in your body for weeks. Withdrawal starts when the substance starts leaving the system, but continues as the brain works to bring it’s chemicals back to normal. But, your pains don’t have to be related to withdrawal. You can know for sure by seeing your doctor and getting examined.

  131. I need help! I finished weaning off Paxil 40mg 2 months ago due to 30lb weight gain. I finished weaning off Wellbutrin XL 300mg 2 weeks ago. No one will help me, I have seen 3 physicians, been to the ER. The doctor I’m currently seeing wants me off all antidepressants and has me on B complex vitamins and Tryptophan. I’ve been on every antidepressant over the last 15 years. Coming off Paxil was the worst experience of my life, I’m lucky to be alive and that I didn’t follow thru with killing myself. I thought I was past those feelings but now they are back. Severe depression, anger, rage, irritated, suicidal.
    I don’t know what to do anymore. See a psychiatrist? Go back on something? I want immediate help and there isn’t any!

  132. Only took wellbutrin 150 xl for 3weeks and have been off for 6-7 days , had very dry mouth while taking it and a few other side effects ,my question is ,do you think its out of my system yet since i only took for three weeks ,having alot of throat and ear and neck problems and wondering if its related to withdrawl .thank you

  133. I quit taking welbutrin and been experiencing loose bowels and night sweats. Been off two months. Are these problems from stopping that medicine

  134. Hi Nancy. I’m very sorry to hear that. You can call 1.800.725.0922 to get dual diagnosis treatment for your daughter. Best of luck to you.

  135. My daughter has started drinking again after being sober for 3 months on welbutrin
    What will happen to her. She is acting suicidal and her behavior is terrible.
    No one wants to help her

  136. i have been taking 300mg of wellbutrin xl for 15 years. my doc suggested i quit, and cut me down to 150 mg for a month, then told me to just quit. my last dose was a week ago. i now feel as though i have the flu. nauseous, severe diarrhea, and fatigue. how long will this last?? im tempted to go back on the 150mg. Help!!!

  137. i am withdrawing from Welbutrin 150xl since Wednesday. I’m tapering by taking it every other day. Then next week I quit all together. I have aching legs and cramping too, ears ringing worse than usual, face feels numb, edgy feeling on and on. Will ear ringing stop after all the Welbutrin is out of my system. Depression not bad nor anxiety either. Thanks Kim

  138. I have been on bupropion sr 150mg for 9weeks and had extremely dry mouth and my eyes were so dry that I had trouble even getting my contacts out.. istarted having muscle and joint pain worse than usual so decided to stop pill to see if it helped my symptoms. I was on it for mild depression for loss of a loved one. Since I stopped a week ago my dry symptoms have I’m d but I am hurting so bad in my right hip, my right shin and my knees. Could this be from stopping medicine. I also have stage lll kidney disease but has been stable for 6 months. I think I got my lab test saying I had ckd because of taking gabapentin for several years because after I looked it up in my pill book it I decidd to stop. On my next ckd lab work my kidney function had improved. 3 months later improved more almost back o where it was before the gabapentin I took for restless legs. Could this burpropiion have been bad for my ckd. Could withdrawing burpropion be causing my aching body. Should I expect any other bad symptoms. Would, they have shown up by now. I also have been having to get up more at night to urinate..thanks for any help.I somerimes drs. Prescribe pills without knowing side effects.

  139. My doctor increased bupropion from 150 to 300 just 3 weeks ago. The insomnia has been relentless. My doctor’s office never called back about tapering the dose. I stopped taking completely and I have had the worst flu like symptoms ever. The chills just don’t seem to go away. This medication is awful once increased. It’s like I can’t turn my mind off long enough to get some rest at night. Why is this medication still on the market?!?

  140. took Wellbutrin for only 9 days on 75 mg once a day. felt awful going into my 7th day, really bad headaches, forgetful half of the time, right leg numbness dry mouth, felt really gross! i stopped will i have bad withdrawals?

  141. Hi,
    I have only taken wellbutrin for about a month now but recently started itching all over. After researching this found that it most likely was an allergic reaction to this drug. My doctor told me to stop taking it right away and put me on a different medication. That was only three days ago but today I am feeling overwhelmed, depressed and have high anxiety. How long is this likely to last?
    Any advice you can give will be greatly appreciated

  142. Hello –

    I have been on Wellbutrin for 5 months and decided just yesterday to stop, cold turkey, as the weight gain has been significant and I am a havoc workout and “eat right” type. I did attempt to stop taking Wellbutrin a month ago and noticed my weight going up despite my normal workout routine and healthy lifestyle. I started off on Bupropion 150 mg 24HR XL, then requested my doctor increase it to 300mg 2 months ago. Also, I am hypothyroidism taking 90mg of Armour Thyroid. Within the past 5 months I’ve gone from 145lbs to 165lbs and I am more depressed than ever before taking any antidepressant. (Paxil, Pristiq, Celexa) The only one that worked well for me was Pristiq but my insurance company would not cover it and it was too expensive to maintain on my budget. Anyway, my question is, how long will this weight gain withdrawal last? I can deal with the crying spells and just being sad, but I can’t deal well with being fat. I would rather die than go through much more of my days here on this planet being fat.

  143. I have been off wellbutrin for roughly 4 weeks now and am having some trouble. I do welcome feedback, please, to my email address. Due to my financial situation, i was not able to taper off gradually, except for taking half the dose for a couple of days, so it was mostly cold turkey. I did feel that situations that had originally prompted me to go on the meds have fixed themselves, and that i had experienced lots of emotional healing. I experienced exhaustion mainly and dizziness, especially between 1-2 weeks after my last dose. Then things improved and i felt ok, except for fatigue, but now around 4 weeks, it has gotten much worse. It feels like i have a lot of inflammation as my joints hurt like crazy, and the dizziness has returned, and the exhaustion has returned with a vengeance. I am really wondering if the meds were poisoning me, as my mind is much clearer now that i am off of them, and i am having so many physical symptoms. Is this still withdrawals or am i having other health issues?

  144. Just trying to keep everyone updated since most don’t still feel so much better I don’t recommend this drug for anyone. I felt worse taking it! Just monitor yourself the first 72 hours you quit after that just stick with it and I promise you will feel so much better! Of course consult with your doc if you still have doubt’s. Its worked for me is all I’m saying and you can do it. Put God first and it will be okay!!!

  145. Its been 9 days! No wellbutrim cold turkey and feel great! Stick with it folks you don’t need medicine to survive!! The first week I was sick but I stuck with it!!!

  146. Been taking Venlafaxine and Bupropion SR 100 2x a day for several years with relatively good, steady results. Lost my health coverage recently (couldn’t afford it) and the prescriptions went along too. 5 days now without the bupropion: headachy, very light headed (or is it heavy headed?), flu-like, tough to awaken, looking for a nap, and wishin’ for sweets! Didn’t feel the need to change anything but, now hope to ride it out and test life without it. Done plenty of internal work and change over the last 35 years so who knows!? Got 30 days remaining of the Venlafaxine. Would be nice to feel strong enough to kick that one too. Been through plenty over the years and can endure a little more. But, will never put up with the depression I suffered in my younger years! Life wasn’t meant to be that hard. So, if the pills are needed the rest of the way that’s fine too! We’ll see. Have courage folks. We’re stronger than we give ourselves credit for -and- we are not our physical ailments. We are so much more!

  147. I’ve been taking 200mg of bupropion for 6 mos. or so. I’ve developed some mood swings and I am irritable and impatient. I want to try withdrawing. Do you think these symptoms are from this drug, and can I safely try to quit using it? Do you think my irritability will decline or get worse if I quit?

  148. The doctor prescribed 75mg Wellbutrin twice daily for me nearly two years ago. It affected my sleep so I ended up only taking the morning dose. It was helpful for that time, but now I want off of it all together. Dry mouth is becoming a problem I need to fix for the sake of my teeth. Today is my first day without taking it. In the past I’ve skipped a few doses and gotten weepy. Today I started drinking green tea with jasmine (both of which are said to sometimes help depression) and a B complex. Anyone have any thoughts on whether these help with withdrawal symptoms? Or what else to do to help with withdrawal symptoms?

  149. I have weaned myself off Cymbalta, which was suggested before weaning the Wellbutrin. I am on 150 mg extended release and want to get off it as my life circumstances have changed and I don’t feel the need for it any longer. I have read all the posts and it seems I shouldn’t stop cold turkey. Can I cut the pills and if so, because the inside is exposed, do I need to take the smaller amount 3x/day instead of 1x/day?

  150. I quit welbutrin (generic) 2/days ago after 3 1/2 months it was the SR kind at 150 mg once a day I also quit the klonopin I was on for 2 months cold turkey past week after going to hospital I kept breaking out in welps so the doc put me on xanax that is the only medicine I’m taking once a day or when I’m feeling anxious. The wells(lumps) under skin have appeared again today on my arm neck and face out of nowhere. I also have had horrible nightmares. Im not sure what I’m asking but is all this related and what should I expect now mentally and physically.?

  151. Hi Rissa. Your body is clearly reacting to the Wellbutrin. It’s best and safest to get a doctor’s appointment. And have your doctor see if this medication is what is causing these advere body reactions, maybe you’ll need to switch to another med.

  152. Hi I’ve been taking wellbutrin for 6 days and I don’t feel right, my heart palpitations are heavy and faster then normal. Not to mention my sleep it’s in livable I jerks awake with shock sensations in the middle of the night but it only happens as I drift to sleep then it jolts me awake again ever 10 mins.. please help is this forever or will it go away over time, I’m scared to death

  153. hi I just left to rehab and stop taking welburtn 1200 mg a day and stoped cold turkey want to know how bad this is going to suck

  154. I have been taking this medicine little over a week now and I feel terrible. I’m gonna quit taking them and when would all the pain and feeling sick to the stomach last

  155. I took wellbutrin for one month to treat my migraines. I had what the dr referred to as a “normal” reaction. I discontinued the medication. One week later I had the worse panic attack. My first.
    How long will the withdraw symptoms last?

  156. A screw up at the pharmacy left me without my bupropion for five days. About a week after getting another prescription, I started experiencing severe rebound depression. That’s been actually getting more severe for ten days now, with no letup in sight, even tho I have been back on the drug. Any suggestions?

  157. I’ve been taking Bupropion SR (300mg/day) for a few years and went off it cold turkey about three weeks ago. It’s hard to tell what’s caused what, but I’ve gained 5 pounds, felt bloated and fat and burpy, and have been tired. I’m tired a lot anyhow, so…? I’ve been more depressed than usual, but that’s not a surprise. I just hope the symptoms lighten up.

  158. I have been taking welbutrin 150xr for awhile now and am noticing some embarrassing side effects that are really concerning me. My appetite has increased significantly but worst of all is the awful flatulence that doesn’t seem to diminish unless I eat dairy products or get up and move around. Is this normal? My doctor seems reluctant to discuss this and says I should just change my diet and drink more fluids. I am feeling better overall but the episodal flatulence is a horrible dilemma that has caused me to shy away from social activities as my bowels erupt into a gigantic gas factory that makes it hard to concentrate and can be very uncomfortable. Has anyone else suffered from this side effect? Hoping it goes away soon as I think I’m developing permanent intestinal dysfunction. Thanks!

  159. I ran out of my higher dosage of welbutrin, so I took my smaller dosage I had left over, until I got my higher dosage refilled. Are there side effects? Because I’ve been having a lot of weird constant symptoms for a few weeks. And if so how long will it last, even though I’m taking my regular dosage now.

  160. I’ve been off wellbutrin 7 days now and the only withdrawal symptom I had was a little fatigue in the afternoon. Two days ago I started Sam-e and I feel better then I have in years. No anxiety and my mood is gently elevated. Feeling so much better.

  161. I’ve been off W almost six months. My worse symptoms were fatique and brain fogginess, unbalanced. No fever and maybe I do not remember some. I almost went back on W but I ordered and started taking a Non-gmo brand of St. John’s Wort by Nutrigold. The reason I picked this brand is because their products have received certification by the Non Gmo Project. That means there are no gmo ingredients. I took these for a week as directed. Desperate to feel better I doubled the dose the second week and started to feel a little better on day 14. I’m in my fourth week and am still taking double what the directions say. I have to say the fatique is not as bad. I still have to take some big pharma speed to get anything done but, there is definitely some improvement. I don’t have any anxiety because I don’t go anywhere but, I tried some pot the day my sister died and I was surprised how calm I felt. So I’m looking forward to medical marijuana being passed. Fyi, I read that in some people in can take up to two months for St.JW to fully kick in. I have my finger crossed. I highly recommend this brand of St.JW because I feel the difference and because it has no gmo’s. Some of you are having other symptoms. It could be from some other drug you are taking and it also can be from food you are eating. If you are eating anything with aspertaine in it, for example, diet anything, this will cause migraines. Because of the gmo food, more women are entering menopause earlier in age – hot flashes. The top foods to try not to consume are corn, soy, canola, sugar, papaya, cotton, yellow squash, zucchini, alfalfa, and now they are coming out with gmo potatoes (McDonald’s French fries) and gmo apples. Go to you tube and watch “Genetic Roulette.” It will explain what “substantially equivalent” food is. It may be why so many of us are sick.

  162. I have been on Zoloft and Wellbutrin for many years (zoloft ~ 15 years; wellbutrin ~7 years). I want to ween off both of them this summer and am wondering if anyone has advice whether to start with Zoloft or Wellbutrin. I assume it’s best to do one first, then the other, or doesn’t it make a difference?

  163. Thank you Jennifer! I saw my doctor yesterday and she also said to quit cold turkey. Today is day one. Wish me luck!

  164. I recently quit Zyban (Wellbutrin) cold turkey and had zero side effects, there are though, effects from beginning, such as insomnia, agitation among other things. I spoke with my doctor before stopping and he okayed it to go cold turkey!

  165. I’ve only been taking wellbutrin xl 150 mg for 3 weeks, while at first I thought it was helping, I’m find myself anxious, numb or extremely angry. I had a complete crying fit that lasted hours ,2 and half weeks into taking the medication. I’ve never taken any other antidepressants. And now I’m afraid to, Since I am on a lower dose and only been taking the medication a short time would it be safe to quit cold turkey?

  166. I have taken Wellbutrin for 15 years. I am currently weaning off my 150mgs very slowly. However I have experienced gaining about 20 pounds already over te 1 month period I have been tapering off. I exercise daily and eat healthy. Is this weight gain going to be permanent or will it go away after a month or two off Wellbutrin?

  167. on Wellbutrin XL 150 for 1 1/2 months. Began to have bad dreams and unusual thoughts
    .I’ve had a panic disorde for yearsr and take Xanex 1-2. 1.0 daily most days none daily unless in Panic and then 0.5 daytime and 1-2 1.0 at night of Xanex. While the Wellbutrin has slowed the Panic issues daily. I NEVER HAD DEPRESSION before and NOW I am having bad dreams , sorrow and depression. I WANT OFF THEM NOW !
    and feelings and depression.

  168. Mines sort of a different situation. I go to a Mental clinic so I can’t get normal refills on my medication unless I see the doctor and councilor every month. I missed an appointment and therefor was off my meds a few days. I’ve done this before when I was taking 150mg of Welbutrin 24 hour release tabs and didn’t see the doc to get meds for a whole month with not one withdrawl symptom. My doc used my dose to 300mg(which I didn’t think I needed and will be asking to drop back to 150) I missed my appointment a week ago. Two days after said missed appointment I woke up extremely depressed. Worse than I had been before meds. That night at midnight I started feeling extremely dizzy, nausious, racing thoughts, felt out of body,shakes, muscles tensing, had a panic attack, and had to be brought to the ER. Had no idea what was going on. They sent me home telling me I had a virus, positional vertigo and a panic attack. I took some nyquil and went to bed for a good while. Woke up the next morning and it started over again about an hour being awake. Then quit. Then happend again that night for a couple hours then quit again. Like a roller coaster of feelings, depression, dizzyness, small shakes, muscles tensing, drymouth, nausea (haven’t eaten but once in three days), anxiety and just feeling not myself. Thankfully I called and got my doc to let me go get my pills and he wrote 150mg dose for a week then two a day after that. I’m NOT taking two a day. I’ll stay on 150mg. Yesterday I had just one episode and today I’m feeling a bit weird and cloudy, still worried and scared that it might not even be withdrawls but that’s what a pharmacist told me it COULD be. I absolutely hate feeling like this. I have two kids to tale care of and it’s scaring me to be alone with them much less myself. I have noticed less episodes since starting taking my 150mg dose but I’m wondering if anyone has had this happen and if I could get a roundabout time line till when I can expect to feel freaking normal and not out of body, freaking weird. I was off meds for three damn days. And I felt like my entire brain shut down 🙁

  169. I am sort of in shock right now…. I was on Wellb xl 300 for 5 months and got off of it because I didn’t really feel like it was adding to my life. I was irritable and stupidly over focused on nothing that really mattered and sort of floating above myself questioning my own personality. Because I have eating disorders and a warped view of what’s real I decided to get back on it 2 months ago because I had gained weight and prozac just didn’t cut it anymore. I’ve been on a pill buffet of trying things for the past 7 months and I quit. I’ve been sober almost 2 years now {drugs and alcohol} and I have the unbelievable support group and tools to use in life. I have a relationship with a god as I understand…
    The reason I’m writing is because I just realized how sick the Wellbutrin makes you the second you get off it. I had the stomach flu hard core and immediately got the cold flu after… and I’ve gained 5 lbs… Now thinking back from the first time I got off Wellb I was totally sick for 2 weeks {while in Hawaii on Vacation!!} It’s the Wellbutrin. I don’t get sick like this. As nuts as I think I am… I’m healthy and strong and I can do this. And I know you guys can do this.
    These drugs are poison and a lie. They do not know what the side effects or long term damage these drugs cause. In a way I’m relieved I know this now.

  170. Been taking Wellbutrin since 2006 and finally decided I didn’t want to take it any more. Main reason is my blood pressure is getting high and I am going to have to start taking bp meds. I really don’t want to go down the path of taking pills to offset the effects of other pills. Just seems stupid. I was originally put on Wellbutrin ‘weight control’ if you can believe it but I quit. Then I was put back on it to help manage anger and a flash temper. Went back off briefly when I moved to a different state and lived by myself and anger problems came back. New doc put me on Effexor early 2005 which sent me into a 2 month long nightmare . Nasty nasty med. Back to Wellbutrin and have been on it ever since. Since that time I have been diagnosed with sleep apnea and ADD so have often wondered if anger could have stemmed from apnea and ADD. Time to find out.

    Been off Wellbutrin for 2 weeks cold. No physical symptoms really. Don’t feel sick or tired but flash temper is back. Interesting to note that my adderall has gradually been becoming more effective. While adderal is actively in my system, I feel good, and have no anger problems, almost opposite really. Near end of the day, when adderall is gone, I am very quick to anger and have to be VERY careful around family. I often run to the garage or risk being a total ass at times. Eating sounds push me over the edge. Another odd thing, I am sleeping better. Noticed today that my creative mind suddenly started to splutter back into existence. Been 8 years, like having an old friend back. I think being on adderall has helped mitigate some of the withdraw problems.

    Today was an interesting milestone. I was very optimistic about the thought of being done with it. I want it gone from my system and I look forward to the day when I can say Wellbutrin is no longer a part of my life.

    I have not noticed any appetite changes. I am morbidly obese so that doesn’t surprise me. I always want to eat crap anyway so you really can’t say it changed my appetite.

  171. I hadn’t initially wanted to go off meds but, due to depression from watching a young family member suffer from the affects of gmo food, I was forgetting to take my meds. After finding out that there were gmo sources in meds and vitamins, I decided to try to withdraw from Buproprian (Wellbutrin generic, 450/day for 17 years) and Amphetamine Salts (Aderill generic for ADD 10 years). I initially had been missing several days in a row and did not know where I was as far as dosage so I just took one pill a day for about 2 weeks, then I started skipping 1 or more days (took about 3 months). I’ve read over the many symptoms of withdrawal for this drug and I only had a few symptoms. (Wondering if some of the symptoms are just scare tactics.) Horrible fatigue, sleepy or can’t sleep, balance, rare blurry vision (morning). The worst part has been the fatigue. I am still fatigued and if I have to do anything I have to take a A.Salt pill. I was hoping that I’d be able to stop taking the A.S. med but, I’m not taking any more than I was before so I’m not worried about it. Please factor in that I have been off gmo food for over a year; I was able to stop taking GERD meds at 3 months off gmo food. After learning about our bought off, corporate controlled government, I feel that we all need to get off of gmo food and as many big pharma drugs as we can. Please learn about gmo food. The governments of Canada and the USA and legally poisoning their citizens via food since 1996 and wait till you find out what it has done to our kids – Autism 1 in every 68 kids – there’s a reason for that. See, You Tube, Genetic Roulette: The Gamb1e of Our Lives. It’s 1:24 minutes and you should watch all of it.

  172. Eleven weeks cold turkey after three years of 100 to 150 mg per day. Six weeks of nose running, flu, body pain, and an appetite that would have made dead rats look good if you offered me catsup.
    Another six weeks and the appetite on waned a little but the mood finally improved. Now, two weeks of 100mg per day. Obviously I did not have a complete recovery of receptors but at least my appetite is in control.

  173. I was on 150 xl wellbutrin for 10 years. It served me well, helping me to focus,and keep my energy levels up. I started tapering off about 7 weeks ago. Over 3 week period, I weened myself off by skipping a pill every other day, skipping pills for 2 days, and then on week 3, I took only 2 pills. I was having no withdrawal symptoms so I stopped at end of week 3. The first week of no pills I I got a bad cold, headaches and flu like symptoms I also began having severe heartburn like attacks mostly during night. I have now been off wellbutrin 2 1/2 weeks and physical symptoms are no better. Has anyone else had any gastric type symptoms and if so what were they like? I thought that withdrawal from only 150 mg would not be so vicious..

  174. I am now into my fifth week of cold turkey after two years of between 100 to 150mg Wellbutrin per day. My appetite nearly made me a feral creature, or a Gollum wannabe. I could open the fridge and say “mine, all mine” The appetite has slowed but not gone away. I have been an OCD nail biter for many decades and only Wellbutrin ever killed that habit. At five weeks I am slowly, slowly returning to the habit. I suggest that per my prior experience and thorough reading that the long term effects are finally wearing down but not yet gone.
    Still have flu like symptoms with a running nose, very hard to get up in the morning, etc. It will wear off and your brain chemistry will return to normal. In my case “normal” is not what I want, I want the effects of Wellbutrin and I am willing to go through this miserable period in order to hopefully “buy” another year or two of the positive effects.
    The literature does not cover withdrawal in any significant fashion, withdrawal does not sell the drug or make a reputation so your best source of information is to study everything and perform your own “Meta study” by reading hundreds or even thousands of comments and look for common themes. Best of luck.

  175. I am 3 weeks off of 150 XL Wellbutrin. I had been on it for about 4 years and felt very good. It helped take the edge of some very difficult times dealing with parent care giving, death and my son’s teenage antics and my own disability called FSH muscular dystrophy. I thought I wanted to crawl into a hole and die….just take me away and put me out of my misery. Life was getting to be to much on my own without a support network. So, I found the Wellbutrin was a God send. I gained weight after being on it for about a year. about a month ago I started getting swelling in my throat, my tongue and lips were burning and it was so uncomfortable. I got up numerous times throught the night to go to the bathroom and could not stay asleep. Often, waking at 0330 or 0400 and just staying up. My Doctor was not available when my throat started swelling and it would take 3 weeks to see him so I talked to my pharmacist. I went off the drug cold turkey….carefully monitoring how I felt because I did have a supply of pills. You cannot take 1/2 tablets because to much goes into your system at once. The only real side effects were feeling slightly weepy and lethargic with no desire to get anything done. I have gained 9 pounds in three weeks which is a real problem, because it has just taken 10 months to lose 25 pounds. But, Dad is passed, my son is in university and now a lot of what were my issues are gone. I would like to clean my system up and feel my authentic self again. My concern is have I altered my body chemistry forever, or, will I be able to find balance again.

  176. I have taken Wellbutrin for over a decade and quit several times. When it is working for me I lose weight, exercise, organize and feel great. Then at the longest after a year it just stops working. The withdrawal symptoms are flu like with running nose, puffy eyes and fatigue. The trouble is that in order to get the good effects of Wellbutrin I have to quit for at least six months. The endogenous production of Nor Epinephrine and Dopamine are suppressed for a term and degree that appear to be directly related more to length of use than dosage.
    I have been weak and returned in the past after a couple of weeks but my only true success has been after suffering the Hell of weight gain, fatigue, and loss of concentration until the symptoms subsist.
    Wellbutrin is nearly unique in it’s actions so there is almost no literature on the long term effects or the “poop out” that many people suffer.
    I suggest through a lot of reading and a lot of experience that doctors and patients go to a 350 mg dosage far too rapidly in order to get an immediate solution. You may find that if you ever start again that taking only 50mg per day will have the same effect if your are willing to give it a month to six weeks to work. The flip side is that the half life of the various components of Wellbutrin can be as much as 3 or more weeks giving an amazingly hard path to figure out how long a withdrawal will last.
    I have never found a med that has such profound positive effects, effects that are so good that I find it worth while to go through this to have at least another year of being high functioning.
    Summary: You will not find any good medical literature on withdrawal, you will need to study the pharmacology of the drug, drug addiction, and draw your own conclusions.

  177. Hi Everyone,

    I’ve had a lot of issues getting off. I was on 300 mg for almost 3 years. I no longer needed this medication and tried to coming off on my own and had horrific anxiety, headaches, dizzyness and brain zaps.

    I’ve now been weening off for about 4 months. I went to 150 xl for two months, then 100 sr for a month. I’m now on 75 mg hcl and I’m going to stop these in about a week.

    Today, I still have some headaches and I get dizzy spells. The scariest part has been driving. I’m not able to go long distances on the interstate right now because I almost feel like I’m in a tunnel.

    This is getting better, and I’m determined to get off of this medication. I find it evil and wish I had never started it. It was an aid to quit smoking, that battle was won, but I don’t think I really needed this pill to do it.

    For all of you suffering out there from getting off of this medication, stay strong. I can tell I’m getting better and I’m giving myself months to fully recover even from now. Do some research on natural supplements on omega 3 TG and even some other herbs that can help with anxiety.

    Medication has it’s uses, but I still feel we are the owner of our domain. Stay strong, stay committed. I know this sucks for many of us, and I’ve had some battles with injuries.


  178. Okay people as a long time on and off start and stopper of wellbutrin (at varying doses for varying lengths of time too) I may be able to give you some useful advice:

    First off, the withdrawal is not that bad. You’ll be fine. If you take more than 150mgs you should consider weening yourself off rather than quitting cold turkey–though even if you DO quit cold turkey, keep yourself grounded and don’t let yourself develop hypochondria (yeah it’ll be a little rough for awhile but you’ll be fine soon enough). FYI you can easily taper off this stuff by cutting your tabs in half. YES, even the SR tabs can be halved bc the ingredient that sustains their release is evenly mixed throughout that tablet.

    Second: if you are having fatigue (and you will get lots of fatigue if you go cold turkey) or feeling all achey or even just lazy, you might want to try drinking Yerba Mate. I know I know it sounds iffy but just check it out cause it’s a bit like a natural wellbutrin in that it’s got stimulating properties as well as relaxation properties in the form of caffeine and minerals. Yerba Mate is basically the South American version of green tea (find it in health food stores–even regular stores usually have it). I like it mid-morning or afternoon cause I like my coffee in the morning. Tastes like crap but it could really help you out right now.

    On another note, if you think wellbutrin makes you gain weight consider whether you’ve quit smoking or not, cause that could also be a huge factor. I know this seems like a no brainer but I used to fervently believe that wellbutrin made me gain weight but I only realized a while ago that it was the whole quitting smoking that made me gain. A lot of times i would start taking wellbutrin when I was trying to quit, so go figure. I quit smoking more than a year ago–and i did it cold turkey (no wellbutrin or anything until later) and my weight went up 10lbs for like 6 months. For the past few months I took 150 mgs of wellbutrin and lost weight so I no longer think it had anything to do with it.

  179. Hi my name is Florence husband has been taking 450 mg’s of Wellbutrin…XL for the past 4 yrs. last week gave them up cold turkey. has stomach cramps .very tired feels sick & agitated. he is not a drinker as such but last night was with a friend & drank 8 or 10 big glasses of draft beer. came home & was very sick throwing up & moaning all night long cant eat or drink anything he is sleeping a lot I explained to him the danger in giving up this med. & he think’s it’s from something else .anyway my daughter taught she would have to get an ambulance for him & he is the same Same .what should I do is there a happy medium a loss.

  180. I had been taking Welbutrin for over three years at a dosage of 300mg XL. I’ve quit cold turkey for a few weeks or days or so before, but had never experienced any effects. Now, that my doctor refused to fill my prescriptions and I didn’t find another doctor in time, I felt unignorable symptoms after about two weeks. I wasn’t in any rush to find another doctor because I’d stopped taking it before no problem. I got more emotional, but nothing I hadn’t experienced my entire life before Welbutrin. But the scary thing is, I started taking it again after two weeks after I was rushed to urgent care (not knowing what was wrong) and have been taking the pill since the 26th of November and it hasn’t gotten any better. I know it takes awhile to get into your system, I’ve heard up to four months, but I’m seriously scared. Now onto my experience.. this was the worst experience of my entire life and even after one month and a week, it’s still not over. I experienced EVERY SINGLE SYMPTOM. In EXTREME intensity. I didn’t think I was going to make it. I have bipolar, anxiety, and depression, so I imagine this had a lot to do with the unbearable paranoia and panic attacks. Physical symptoms didn’t last too long. I still have them every once in a while but for some reason I got better, and then I got worse. I went a few days where it wasn’t easy, but I could stay at my own apartment (I’m 18) an hour away from home. Now I can’t leave my mothers side. I have to go to college and have been forced to go there every day an come straight back. I’m afraid of EVERYTHING and I know it’s still from this withdrawal. There are times when I can sit there and psych myself and nothing happens, that it how I am normally. Now my heart races from the moment I wake up to the moment I go to sleep and any troubling thoughts can induce an “episode”. These episodes have been like having an extremely bad trip while riding a rollercoaster on crack. Now the episodes are scarce, but the emotions are unbearable. I’ve never been one to consider suicide and actually try to do it, but the feeling is so overwhelming there is no thought process and not even my mother holding me can make it any better. I started crying which felt kind of good, to just let it all out, but soon it became uncontrollable. And since I couldn’t think no matter how hard I tried all I could feel was “death, I have to die, stop, death” . I’m petrified that that will happen again and I can no longer live a normal life. Some people say it can last up to two months but that it’s supposed to get better over time. I’m scared to say the least and can’t live a normal life.. all I can keep thinking is that even after two months this is never going to stop. I need serious help and no one is giving it to me or giving me any answers.

  181. I took wellbutrin sr 100 once per day for about 20 days and stopped due to intense migraines and dizziness Should i expect or worry about withdrawal. My doctor has started me on lexapro 5 the day i stopped wellbutrin. I am having some increased anxiety

  182. I have been off of Wellbutrin SR for about 5 months now…. maybe that long… i stopped cold turkey. (yes i know dont do this but long story) it took about 5 weeks for the dizziness, irritability, etc to stop but eventually it did. fast forward 3 months and i start feelign those highs of VERY happy and lows where i would start to cry when talking about something thay would upset me…. not tooo bad but enough to bother me a little. NOW about 2 weeks… (im guessing its the withdrawals) but im sooo dizzy i can sometimes fall over… Im irritable, and VERY sore all over…. uncoordinated and feel fat fingered. should i get back on the drug??

  183. I started taking 150mg Wellbutrin to quit smoking on September 6 2013. Around October 6th I stopped taking it due to severe joint pain in the my shoulders and knees. The pain was so bad I could hardly walk or sleep. Two weeks after stopping, the pain reduced by 50% but never went away. Any idea how long this will last?

  184. I want people to start requiring their doctors to do a more in depth analysis of what’s going on in their body before determining that its a depression that can only be fixed with a pill. We, the patients, are making it way too easy for doctors by simply taking whatever they prescribe to us instead of doing our own research and asking questions….this is their job!!! The body is a chemical factory and there are many reasons why we get symptoms of depression, weight gain, headaches etc. but there are usually underlying reasons that can be fixed through blood tests etc. I found out my thyroid was off and it caused me all kinds of symptoms but one was depression….the doc just put me on Wellbutrin and I have been on it for 6 years until I finally had more tests done to find out my thyroid was low….now I am having a hard time weaning off of Wellbutrin which I never should have been prescribed in the first place…….people, do your homework and own research about what’s ailing you before you let a doctor give you a pill!!!

  185. I started taking Armour Thyroid for Hypothyroidism but have been on Wellburtrin for the last 6 years and tried to quit cold turkey thinking that it could interfere with this thyroid med. I got severe headache and could not even think straight so I started taking the Wellbutrin again. Does anyone know if its dangerous to take both of these together since they both speed up your body’s chemical processes??

  186. I was on a very low dose to help with the side effects of quitting smoking. My instructions were to take once a day for a week and then twice a day moving forward. I continued to take my dose twice a day for two or three weeks and ended up not liking how if made me feel so I stopped taking it w/o weening myself off of it. Now, almost 3 months later I continue to become more depressed/paranoid and am agitated at the drop of hat. Is all of this part of the withdrawals?

  187. Hi,

    I recently quit all of my anti-depressants (wellbutrin and paxil), unfortunately cold turkey, about a couple weeks ago. I am extremely tired, in a fog and a bit dizzy as well as irritable and have gained weight. Luckily though, I have not had withdrawl symptoms regarding my depression, therefore have been able to handle the few symptoms I do have with no worries, but it is difficult getting up and getting my day started and going throughout the day, due to my tiredness. Is there any natural remedies you can recommend that can help me with energy?


  188. Spouse took Bupropion for approx.4-6 wks in addition to Prozac (he has been on for years) He was less depressed but started to have increased dble vision problems, forgetfulness, balance problems and slow response time with thinking and driving. He weaned off of it for about 10 days and has been off bupropion for about 10 to 14 days now and still has these problems. any comments or help???

  189. Been on Wellbutrin XL 150mg per day for about 5 years. I am currently under the recommendation of my doctor tapering. She advised 1 pill every other day for 4 weeks and weeks 5 and 6 will be 1 pill every 3rd day. I have been nauseous, and had GI issues for the last 7 days. Is this normal? Today I am feeling very tired and I am thinking this could be the withdrawal symptoms too. I am just wondering (since I can’t find information anywhere) how long this feeling of discomfort will last? Any help would be appreciate…I can’t get a hold of my doctor for several days…

  190. Feeling very agitated over situations that normally I would only be irritated, but not act out my displeasure or vocalizes at inappropriate times. Headaches, insomnia, stomach pains and at times tearful. Angry often…at self, others….
    Reasons for quitting med is due to severe constipation (from going daily to maybe 2x week with a med to help) and weight GAIN ( not everyone loses weight w/this med apparently). Plus I was getting thru a difficult time w/help from this med, and felt I developed strategies to cope better.

    I feel physically&emotionally drained….but feel in the end it will be worth it. Sigh

  191. Thank you, The food cravings went on for 15 days and 7 lb gain. Woke one morning and the cravings were gone. I am now off of it 2 months and doing well. No more dry mouth and able to read a book. Thank you for your help!

  192. I have quit the Welbutrin for a month now and have gained 10 lbs. I am so hungry. I read all of these posts but nothing about the success of being off longer than a few month. Has anyone made it without this med?

  193. I am so discouraged! Just when i’m fully compliant with taking all my medications wellbutrin ends up giving me severe side effects. Because these side effects were so severe I had to go off cold turkey! Almost immediately after quitting the wellbutrin I felt so tired and extremely depressed. I was fighting back tears daily. I got so down I quickly took one pill just to keep from becoming suicidal. Fortunately I heard from my pdoc and she has now prescribed something else which I start later today. However, early this morning I experienced extreme feelings of dread, rapid heartbeat, and a feeling of almost blacking out. I cannot sleep. I heard that cymbalta works the same as well but run so I may get the very same side effects as I did on wellbutrin. I hope not. It has taken me a long time to find something that works! Meanwhile I hope these withdraw symptoms don’t continue too much longer.

  194. Hi,
    I stopped taking my wellbutrin 150 mg xr on friday (5 days ago). With chronic insomnia, i took benadryl last night to fall asleep and today i have felt nauseous ALL day long. I am also very concerned about gaining weight in withdrawal. I gained weight on it and have been unable to lose weight despite daily excercise and food journaling. Is the possible weight gain you discuss in the timeline a result of increased appetite or is it due to the drug itself?

  195. “flu like symptoms making you severely sick”

    This is for real. I stopped mostly cold turkey and and a sickness snuck up on me after 4 days and it got bad. Started out with a stuffy nose, then the next day constant drainage and sneezes that hurt. I finally realized it was because of not taking the medication. I never get sick, I’m a 24 yo. fit male. But this got bad. Taper off your meds people.

  196. I stopped buproprion cold turkey after taking it for at least 4 years. Within a few days I ws extremely sick, fellt like I had the worst flu ever that would not go away. My psychological syptoms did not even matter becuase i ws so sick. It took all i had not to go back on it for the first several weeks. Getting from the bed to the couch (in an apartment) was excruciating. I am glad I did it so far, but I suggest being very determined if you go off it like I did. I am still suffering, including emotional ups and downs and moods, after about 6 weeks. But, after about 4 weeks I knew I would make it. I practiced such discipline during the temptation to go back on it. Don’t get me wrong, I was not addicted. It was prescribed and the doctor did not know of my decision tos top the meds. I just wanted to be responsible for my own self and no longer wanted to deal with the dependency of medicine.
    I think what makes you gain weight, of which I wold say I gained 3-5 pounds but then shed it recently, is that your muscvles are like jello and your activity level drops so much so burning calories is impacted. Besides, as a long term fitness person I could hardly hold a soup can let alone a 20 lb weight in my hands.
    My advise, be aware! But, I am so glad I did what I did in hindsight.

  197. Hi,

    Last December my psychiatrist prescribed Wellbutrin on top of the 40mg celexa I am taking because I was very depressed. I just had a miscarriage then, and have been on celexa for 4 years. I only took Wellbutrin because I trusted my doctor. And he said there would not be any withdrawal symptoms. I did not feel that depressed when I started taking it. After a few weeks I was on it, I started to feel nauseous to the point I got sick. I was taking at first 300 mg for two months before I got nauseous, then I tappered off to 150mg for a few weeks, when that really made nauseous, under the care of my doc I went off. My questions are, is it possible that Wellbutrin knocked off my celexa? It’s been five weeks since I have been off, and my withrawal symptoms are tough. Anxiety, some rebound depression, crying spells, fatigue. If I only took it for 4 1/2 months, can the withrawal symptoms last months?

  198. I was taking this medication for 3 years- they put on on Welbutrin while I was in rehab detoxing off optiates. Anyways, it medicine helped me a great deal over the past few years and although I don’t have any negative things to say about the drug (it got me through one of the most difficult times of my life), I recently made the decision to taper off. Being a person who is easily drawn to things that make them feel good (hense the stint in rehab), I knew I was finally at a place in my life where I could handle my day to day problems without the help of any outside substances. And that meant out the window with ANY kind of mood altering drugs, including my Welbutrin. It’s been 10 days now since I took my last dose, and I wanted to write this posting so that others out there reading, going through the same things I am right now, could KNOW they are NOT along in this!! Sometimes we make the mistake of thinking that we’re the only ones feeling the way we do…and this doesn’t help us what so ever. I’ve literally gone from the flu (I read it’s “flu like symptoms, but no way, this WAS the full blown flu, and probably the worst one I have experienced in over a decade). After that, the most hard core doses of fatigure you could possibly imagine. I’m talking 2, 3 naps a day… dosing at work, in class, in the bathroom… It was a struggle, and still is, just to pull my ass out of bed in the morning. All I want to do is sleeeeeep, 10 hours doesn’t even cut it anymore. I’ve also felt very dizzy, and loopy,…a kind of fuzzy, don’t know whats going on around me feeling, which has been a bit frightening when it kicks in. Running into walls has been some side effects of this. I’ve also felt extreme muscle aches in every inch of my body for about 10 days now- where it feels as if I worked out and pulled muscles. Theyre soar and swollan and even walking was difficult one day b/c of how tender the muscles in my thighs were. And last but surely not least has been the awful, pounding, never seeming to subside heachaches!!! I’ve probably taken 50 pain killers (over the counter stuff) since this whole withdrawl process began, and it just doesn’t help ease the pain at all. They come and go with the pain releavers, but never completly. It sure has been one hell of a ride so far and I keep asking myself, “am I doing the right thing? Do I truly need to be off this medicine if I’m going through such hell?” I know in my heart of hearts though that I have weatherd MUCH tougher storms, and that if I just hang in there, and hold onto my faith things I can do this, then anythign is possible. You guys can too! We need to learn how to be a society that can function without pills, and being able to rely on oneself is a powerful thing! Lets not underestimate ourselves and what we are capable of. Good luck to all of you out there who have made the same choice as I have… My prayers go out to you!

  199. Barbara, I have quit taking 350mgs of Wellburtin after only one month of taking it numerous times and usually all that happens is the first day you feel a little more tired and maybe a little hungrier than usual but that’s about it. Heh, I like taking wellbutrin for only a month because it helps you lose weight in the beginning (though long term it totally makes you gain!). Anyways, don’t worry about it cau you probably not even feel tired since you we’re on such a low dose.

  200. I was on Wellbutrin for three weeks this past Monday. When I called the doctor last Thursday, it was because I was having some side effects that I was not happy with. I had extremely bad arthritic pain in both knees and in my right hand. It ws hard to walk up and down the stairs or to open a bottle of water. I was forgettling to give my mother her meds and to that the doctor said use an alarm to remind me. I was however sleeping better, not over eating (lost a few pounds), feeling calmer, but starting to have bad heartburn. The doctor said to stop taking the Wellbutrin. I said, “don’t you have to wean off of it?” She said, “No. That’s one of the beauties of Wellbutrin.” Today is Wednesday and I have not had a dose since Sunday. I was on a very low dose. The doctor told me to make an appointment with an orthopedic about my hand and knees in two weeks but if my pain went away, it was probably the Wellbutrin and to then cancel the orthopedic appointment and come back to see her. I was meeting friends for dinner last night and called my pharmacist to see if I could have a glass of wine being that I was coming off the Wellbutrin. The pharmacist said, “You can’t just stop taking Wellbutrin like that and do not have any wine until you see what withdrawal you might experience.” Had no wine, but now I am a little scared about how I will react with the withdrawal. I have fluctuating blood pressure problems and on Monday my BP was the best it’s been in years. I need to watch my grandchildren tonight and I’m afraid I may not be able to. The only other meds I take are Synthroid and Furosemide. I’m more than a little nervous right now about what I might experience because I just stopped cold turkey. I’m unsure why my doctor doesn’t know about this and why she didn’t double-check herself when I asked specficially about it.

  201. Is it normal to gain 5 lbs in the month you quit wellburtin? Will it eventually go away? I’ve been on this stuff for about 6 months and in that time Ive developed constant lethargy and a weight gain of about 10lbs, so I decided to stop last month. I somehow gained 5 more lbs in that month when I stopped taking it despite tracking my (already strict) eating and exercising habits! I went back on, it and the 5lbs dropped instantly, but I’m still 10lbs heavier than last year and I’m back to being constantly tired and unmotivated (except for feeling fat and bloated, I felt so much better when I quit this stuff!). Is this normal? Will the weight gain eventually go away if I quit it again? I’ve never been so heavy in my life and my dr is always dismissing my concerns cause I’m not technically overweight (so annoying!). I will NEVER go on an antidepressant again, that’s for damn sure!

  202. I’m experiencing insomnia. Is this a symptom of with drawl and if it is how long will it last.

    I have been taking bupropion SR 150 SR x 2 for almost ten years.
    I’ve tried to tapper off many times but end up giving in and going back on them.

    I accidentally quit cold turkey (I was sick and slept alot for about a week not taking my meds or vitamins) so I figured why not use this opportunity to quit.

  203. Hello Roxie. Do an online search for the following words to find information related to tapering Wellbutrin: wellbutrin taper

  204. I have been taking 150 mg of Welbutrin XL daily for several years to help me cope with some depression. I am interested in weaning myself off of it now and seeing if I can get along without it. When I asked my doctor about discontinuing the Welbutrin XL, she suggested that I take the medication every other day for several weeks and then discontinue it altogether. When I did some research on the Internet, I found articles alleging that it was dangerous to skip doses completely in this way and that doing so made it more likely that I would experience side effects from the withdrawal and that those side effects would be more severe. I will be seeing my doctor again in a couple of weeks and intend to raise this matter with her again at that time. Can you give me any recommendations of articles that I could read that would give me some background information on discontinuing Welbutrin XL? What would you consider the best way of achieving this?

  205. Hi Kari. I’d suggest that you speak with a pharmacist to confirm possible connection, and also with a nutritionist or personal trainer to set up both a nutritional and exercise plan. Combined, these experts can help you achieve your goals of weight loss and health!

  206. Hello,

    It’s been 4 weeks since I took my last dose of Bupropion which I was on for 3 years. Since I stopped taking Bupropion, I’m constantly fighting hunger pains which resulted in a 5lb weight gain. It is extremely frustrating because I continue to gain even though I watch my calories and work out regularly. How long can I expect the weight gain and hunger pains to continue? Above you mentioned possible weight gain 3 to 4 weeks after stopping the use of Wellbutrin. I’d like to loose the weight I’ve gained and want to know when my diet and exercise will not be directly effected by Bupropion? Thank you

  207. Hi Ed. I did a cursory search using these keywords: bupropion side effects

    I found that muscle or joint pain can be side effects of taking bupropion. However, nothing mentioned as a side effect to withdrawal. I’d suggest that you consult with a pharmacist for more precise phamacological effects, and seek help from your prescribing doctor for more information.

  208. I had been using Bupropion for 5 years and have recently sopped using it. I spend several months being supervised by a Psychiatrist. I had minimal side effects, mostly gastrointestinal. But since I have been off the drug now for a couple of months I have been having extreme muscle aches. I was wondering if these could have anything to do with stopping Bupropion?

    Thank, Ed

  209. Was on Wellbutrin SR 150mg for over a year. Saw doctor and recommended stopping cold turkey. My last dose was Wednesday, today is Sunday. I am fine emotionally, but I am having severe headaches, difficulty staying asleep and nightmares. One of the reasons I stopped the medication was because I was shaky. I’m still shaky. While on Wellbutrin, it made my monthly cycles hell. I have had a cycle yet, but anticipating another bad one for only being off of it for only 3 days.

  210. My husband has seizures. Has stopped cold turkey after 2yrs use of bupropion. Still taking seizure meds. Just wanted to thank you for info. Now know what to expect.

  211. Hi, I’ve been taking 450mg of Wellbutrin XL for several years. Exactly one month ago, I asked my doctor if I could lower the dose. So for one month I’ve been taking 300mg. I’ve just noticed that I have gained 4-5 lbs. Diet and exercise has not changed. Do you think this weight gain is from lowering the dose of Wellbutrin? Have you heard of this happening to anyone else. It’s a big problem for me because I’ve just lost about 50 lbs in the last 2 years. I absolutely don’t want to gain any weight. Right now, I feel like going back up to 450mg again. I only wanted to lower the dose because I’m worried about the long term effects. I’ve been taking Wellbutrin for a very long time.

  212. Hi Leslie. It’s not recommended that you stop Wellbutrin cold turkey. I’d suggest that you ask for a tapering calendar from your prescribing doctor or local pharmacist. Increased, or rebound, anxiety can persist for weeks to months after your last dose of Wellbutrin. Make sure that you have systems and supports in place to adapt to the change.

  213. How long will the increased anxiety last after stopping cold turkey? I was only on 150xl for 6 weeks and have maintained my 100 mg of zoloft.

  214. Hi Vin. I have not seen or read of clinical reports that associate side effects with coming off Wellbutrin. Perhaps there is another reason for fever. Regardless, consult with your prescribing doctor for more information and to seek a diagnosis.

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