How much Percocet is too much?

How much Percocet is too much usually limited by how much acetaminophen you can take daily. In general, Percocet is easy to overdose on, and needs to be taken only as directed by a doctor. More on Percocet overdose, acetaminophen poisoning, and safe dosing here.

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How much Percocet is too much? Taking more than four (4) high dose Percocets per day can affect your liver.  In this article, explain how much Percocet is too much. And we invite your questions about Percocet at the end.

What’s in Percocet?

Percocet is a pain medication that combines both narcotic and non-narcotic pain drugs: oxycodone and acetaminophen. In general, it takes a significant amount of oxycodone in Percocet to be fatal – several times more than the normal dose.  In fact, overdose risk increases if you are getting high off Percocet instead of using Percocet for medical reasons.  And note here that acetaminophen must be taken exactly as directed to avoid serious health problems. How long Percocets stay in system is about a few days, due to the relatively short half life of oxycodone.  But in terms of too much Percocet, acetaminophen is really the main cause of concern.

Percocet strengths

Percocet comes in multiple strengths. This is your body gradually begins to tolerate the opioid oxycodone. Over time, you need increasingly higher doses of Percocet for pain relief. Note here that it takes far less Percocet to overdose if you haven’t developed a tolerance to the medication. Once you take Percocet to manage pain for a longer period, you need a higher dose to get the same effects, which is why there are so many different formulations on the market.

For opioid naive patients Percocet comes in doses of 2.5 mg oxycodone and 325 mg acetaminophen. Stronger doses may have 5, 7.5, or even 10 mg of oxycodone. Some strengths have 325 mg, 500 mg, and even 650 mg of acetaminophen, so read your prescription label carefully to determine how much of this drug you can safely take. 500 mg of acetaminophen is the equivalent of one extra-strength Tylenol.

How much Percocet is safe?

Percocet should only be taken as prescribed – your doctor will be able to advise you on the amount of oxycodone it’s safe for you to take. Never take more than 4 grams (4000 mg) of acetaminophen in one day – but don’t assume that just because you’re under the limit, that the medication is safe. If you haven’t taken oxycodone before, you should be cautious about taking large amounts of the medication

Furthermore, acetaminophen can cause liver problems, even if you don’t take a lot of Percocet. In fact, it’s much easier to overdose on acetaminophen than on the oxycodone contained in Percocet.The FDA is currently advising drug manufacturers to limit acetaminophen in Percocet and other prescription narcotics to no more than 325 mg per dose to avoid overdose. Taking more than 4 grams of acetaminophen in one day can poison you and cause permanent liver damage, even liver failure. So for the highest doses of Percocet, even four pills in one day could cause liver problems.

How much Percocet can you take at once?

In general, you can take 2 of the 2.5 mg Percocet pills every 6 hours. Higher doses of Percocet should only be taken 1 at a time. Just because you have been prescribed a lower dose of Percocet doesn’t mean you can safely take more than the recommended 1-2 pills. Additionally, never take more than 1000 mg (1 gram) of acetaminophen at one time – higher amounts of acetaminophen can cause liver damage which may not be immediately obvious.

How much Percocet to overdose?

Again, it takes between 1-4 grams of acetaminophen to overdose. This is more than two Percocet tablets more frequently than every six hours. Or more than one Percocet more frequently than every six hours at the very highest dose. This is why it’s very important only to take Percocet medications as directed.  For example, snorting Percocet vs oral puts you at higher risk of overdose.

Toxic levels of Percocet in the system

Abusing pain medications, such as Percocet, can result in acetaminophen overdose, especially if more than two pills are taken at a time. How does Percocet overdose occur? You can overdose on Percocet by taking it orally. But taking Percocet in ways other than prescribed definitely raises the risk of overdose, especially if you’re taking an extended-release version of the medication. Crushing the Percocet and either snorting it, or dissolving it in water and injecting it, further increases your risk of overdose.

How much Percocet is fatal?

Lower doses of Percocet may cause permanent liver damage, while not actually causing liver failure or overdose (although overdose is a definite risk as well). Nonetheless, taking several Percocet pills at once can cause overdose, especially on the lower strengths. Keep in mind that just because it doesn’t kill you, doesn’t mean the medication isn’t hurting you.

How much Percocet should I take?

You should take the amount of Percocet prescribed to you by your doctor. Never take more than recommended by a medical professional, and only take this oral medication as directed.

Too much Percocet questions

Do you have more questions about Percocet? Please leave them here. We are happy to help find you an answer or refer you to someone else who can help.

Reference sources: Toxnet: Oxycodone
PubMed Health: Oxycodone
DailyMed: Percocet
FDA Safety Communication: Prescription Acetaminophen Products to be Limited to 325 mg Per Dosage Unit; Boxed Warning Will Highlight Potential for Severe Liver Failure
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. my sister claims to have taken 15 percacet, along with 15 other pills and booze. She was trying suicide, I do not believe her, especially since the hospital sent her home. I don’t believe she took all of what she said and just manipulating us. Could a person take 15 percacet?

  2. Hi! Im taking percocet 8 a day bettew 5 am to midnight or depending of my pain have fybr plus atrithe but i thick i will start puting this down for change oil whit a small amount of thc? Wat you think??

  3. Hi I am on 5/325 started this off taking 2 every 4hrs 12 within 24hrs. Effects wore off due to my tolerance so I decided to take like 4 every 5hrs and the same thing has happened the effects are no longer there. I have decided to go back to 2 every 4hrs to stay safe will I be going into withdrawal for some time until my body adjust to it?

    1. Hi Steven. I suggest that you consult with your doctor to help you plan an individualized tapering schedule.

  4. I started taking Percocet 10mg about 8 years ago 3 times a day. My tolerance obviously increased with time, and I found myself taking about 70-100mgs daily. Which left me short every month so I ended buying them on the streets. At this point, I am not even taking them for pain, but simply to feel good and not withdraw. Current amount daily is anywhere between 120mg (at the least) up to 240mgs all at one shot. I’m surely addicted to them, but have no other drugs or alcohol that I use or am addicted to. It’s just the opiates. Once they sink their hooks into you, it’s very hard to stop taking them. I don’t want to leave my family and go to a rehab… any suggestions on other alternatives to get off of these things? I have never overdosed even while taking such a large amount at one time. Would talking to my doctor and trying an anti depressant help me with the seretonin levels that are probably low?

  5. I take 10/325 percocets once or twice a day. Is this considered too much/ I am 79 year old female. I started taking hem years ago for degenerted disc in my spine from a pain management dr. He was relocated and I since have been referred to a neurologist for stress and anxiety and pain of various
    locations (ibs, gastritis, etc) He kept me on the percocet and added xanax. Right now I take 1/4 of a xanax twice a day. I tremble all the time, I am weak, have bad dreams, terrible palpitations (had ekg two days ago and was ok).I feel like I am dying every morning when I wake up cause I am so weak and the palpitations are so bad. I can’t eat much cause of stomach pain and constipation or diahrea. I am worried about addiction, that’s why I am writing. am I taking too much? I am now 91 lbs. lost about 45 lbs which I didn’t need to cause I look like a walking skeleton. Please help with whatever advise you can give me. My doctor (pcp) does not care so I don’t see him much.I have seen my pcp three times in 9 years.In process in finding another that will accept my insurance. Thank You for reading.

  6. Due to severe pain from.M.S., I’ve been on Gabapenten (Neurontin) and Percocet 10/325 4 doses / day for 15 (yes, 15) years. I never exceeded dose. I’ve been to many doctors. All agree with this. Is taking Percocet this long dangerous ?

  7. I had took one percocet 1hr /2 i took 2 more due to having this extreme tooth ache that had behind my ear pulsing with an extreme headache question is did i take too much

  8. I am a chronic pain patient and go to a pain clinic every other month.
    The doctor has been telling me that I have to cut back on my meds because of the new federal guidelines only want doctors to prescribe a certain am out of medicines. I thought he said the new federal guidelines want doctors to prescribe a total of 100 mg total but he said he knows his chronic pain patients need at least 200 mg a day.
    Do you know what the new federal guidelines say or can I just Google this?

  9. my girlfriend has taken one perc 10 a day but is going through what seems to be dope sickness when she runs out. Is this normal, or do you think she may be doing more with it such as snorting or shooting them?

    1. Hi Michael. It seems to me that she is experiencing withdrawal symptoms. This set of symptoms occur when the dose is lowered or missed. In fact, she has developed a dependence to Percocet. Moreover, withdrawal symptoms happen to people who are dependent or addicted no matter the mode of administration.

  10. I have been taking oxycodone for about 7 years 10/325.I have ruptured discs, fibromyaligia, arithitis and take only as doc perscribes ( i1 every 6 hours) I already have stage 3 kidney disease and is this med making it worse. I tried to go off the oxy but my pain gets too great. I now have a torn ligamate in my knee so there is always some kind of pain. I am 75 years old and know docs push drugs, but am I getting way too much and it is harming me more or is the amount okay. It eases the pain so that I can make it through the day. Ido not abuse the drug but have concerns. I started out with Ibuprofen, then Vicatin and now this

  11. Hi. The day before yesterday I had an episode of kidney stones, they put me morphine and then they prescribed percocet 5-325. I took it as directed : one pill every four hours. It seems to me so much and I don’t know if I am generating a kind of allergy and other secondary effects.. I feel my breathing gets more slow my face is swollen and my skin is itching, I also feel tingles in my hands and dizziness. Should I low the doses? What do you think guys?

  12. I’m prescribed Percocet 7.5 I take 1 1/2 in the morning and I at least wait about 12 or 13 hours before I take another 1 1/2 is that bad?

  13. i take 2 – 10 / 325 percocets before work in the morning for severe osteoarthritis in both knees but dont take anymore the rest of the day . is this safe to do ? i am a plumber and its hard on my knees

  14. I am a female who weighs 550lbs. and I supposed to take 4 10’s a day for chronic pain but I only take 2 1/2 a day being the weight I am can I overdose on 4 or is it safe for me?

  15. I have been taking two doses of Percocet every day for four months now,(7.5-325 in the morning and the same in the afternoon) It seems to lessen the pain but does not eliminate it. I have decided to continue with the same dasage and tolerate some pain rather than increase the dosage and have problems. Is this the right thing to do???

  16. I take 5 times a day 10 milgrams 10/325 Percocet a day iam still in pain been under stress with a bad neighbor that use to kiss me out she’s mentally ill she has been evicted but iam still hearing her Kussing me out please help also iam still in pain

  17. For severe spine pain from M.S. I have taken Percocet 10/325 One 4 times daily for (get ready !) 12 YEARS (along with Neurontin). I’ve never taken more and never less except twice I tried reducing dose. I didn’t crave but it took 2 days to get pain better. My question has long term use studies been done ?

  18. I took about 15 percoets 7.5 ace 325 mg today and yesterday. I am used to taking 80 OxyContin s extended release a day sometimes 1 1/2. I’m reading a lot about Percocet did I over do it? I don’t feel sick in anyway but how do I know if I went to far. Scared to go to sleep because I’m reading I could die in my sleep? Help!

    1. Hi Linda. It shows the acetaminophen/oxycodone ratio. So, this means that your Percocet pill contains 325mg acetaminophen and 5mg of oxycodone.

  19. I take 2 Percocet twice daily for chronic bone pain due to RA and osteoporosis and osteoarthritis. I also on hysingla re 60 mg per day. Is this too much. I am under the care of a very good pain management doctor.

  20. I have had the gastric bypass in 2002, but it is the duodenal switch where I don’t absorb hardly anything. I have also had over 10 surgeries in the last 4-5 years & 3 in the last year alone. I still need to have one more surgery coming up and then hopefully that will be the last one for a long time. Once the majority of my pain is gone I want to get off of this. Unfortunately my back & my foot causes me to take this medication. Right now I take 6 – 10/325 and have been using a fentanyl 25 mg patch every 3 days. I don’t feel the Fentanyl is working and I stopped using it a few days ago because I kept getting a bumpy rash where the patch is. But I totally feel anxiety after two hours when I take one Percocet. I know it’s because the gastric bypass everything that I take goes in fast and out faster. I was thinking it would be best if I do not take the Fentanyl at all and ask my doctor for eight tablets a day instead. A year and a half ago before I knew I needed the other surgeries I literally was Telling my doctor wanted to get off these medications. And I can’t wait too, I would rather live in pain then have to depend on these pills. I don’t even get a euphoric feeling after taking one it’s just about me not having anxiety and taking away a little of the pain. The pain that I have in my foot nothing really helps. Once I have a 2nd surgery I’m hoping that it will get better. I have heard the withdrawal of Fentanyl is very bad so that’s another reason why I really don’t want to stay on it and now that I have not had it for three days I’m doing OK. So my main question is 8-9 10/325 Percocet ok in a day, keeping in mind that I’ve had the gastric bypass. Are there any other suggestions of a combination of medication that would be better than this but that would not cause the physical withdrawal symptoms?

  21. It is Sunday and don’t want to bother my Doctor,if I can help it. I am taking Oxycod/acetamin 5-325mg 2 times a day, i have pain, I want to go to Church, but my foot still pains me, I took the last one over 6hrs ago. can I take one before I leave?

  22. I’ve been on PERCOCET 10/325MG’S for over ten years. Over the past few months I’ve broke-out in rash all over my body including my face and hairline. This is every itches causing me to seek medical attention at the ER hospital and my family doctor. One side of my face would swell and so would my lips. I have been on many itching medications. Does this mean I can’t take PERCOCET any more. And what is the highes doseage in PEROCET?

  23. I take one Percocet a day for a year never abused it just took the one pill for my bulging disc in my back is that safe and will it cause any harm to my body 5-325 can u let me know thanks

  24. Hello, I know a 19 year old girl currently taking 2-20 mg percocet every 4 hours for pain. She was prescribed 160 mg per day by a doctor? I now understand she’s gone up to 180! She awakes in the night and takes them then also. It is taken for tilted knee pain and spine pain, but I never heard of a doctor giving this much medication to a young girl. The mother seems ok with this, is this normal?

  25. Someone I kno takes oxy three times a day every six hours. 8am,2 pm and at7pm but she ended up taking another an hour or two later n on top of that she also takes Xanax at Five. Will she be ok . Accidental od on the oxycodone

  26. I have RA and Osteoarthritis, have had 1 hip replacement, have Diabetes and Kidney Disease Stage III. I’ve been going to pain management for years. I can’t take any arthritis meds due to other conditions. Rheumatologist put me on Methotrexate and soon after was hospitalized 1 week wirh pancreatitis. I quit the rheumatologist. Anyway, I’ve been on Percocet 5 mg 3 x day for 3 years. My pain level is so severe, I can barely function, walk. I know I have built up a tolerance and need more pain meds! My urine screens are always fine. I cannot go on like this in this level of pain. How do I convince them at pain mgmt!!! Desperate in Akron!

    1. Hi Darlene. Maybe you can talk with your doctor and explain that you feel Percocet is no longer providing you with the needed level of pain relief. You may be switched to another pain medication.

  27. A friend of mine has under gone Radiation treatments which is now causing an extreme burning pain. He was advised by the doctors to take 2 5/325 tablets every 4 hours. Pain is very bad and he is taking 12 pills per day in order to deal with the pain.. How dangerous is this?

  28. hi i take one pert 5-325 every other day some times i take the pain med three days in a row only once befor bedtime, although prescription said every 6 hours as needed. my question is will this harm me

  29. To Joseph; How are things going for you? I was disappointed that no one from this blog answered your post. I have no answers for you, I haven’t any medical training. I just wanted to let you know that there were no solutions for you and that I am thinking of you. I don’t know if you are spiritual or not, but I’m going to offer up prayers for you and messages into the universe that you find peace and a pain free existence. You’re not alone, Joseph. I’m sure others were touched by your story as well. Peace to you.

  30. My husband had hip replacement surgery 2 weeks ago. He continues to take his 5/325 of Percocet every fours. Should he be talking to his doc about pain levels since he is unable to go without his percocet every four hours or should we be having a discussion about weaning himself off the medication?

  31. I work with a woman that has had a knee replacement 5 years ago. She has a Percocet prescription that she says is 300 pills per month. She claims it is 10 pills per day times 30 days as prescribed by her Dr. She was admitted to the hospital about 6 months ago as her kidneys failed. She claims the reason for it was too many anti inflammatories over the years and it was the naproxen that did it to her. I’m confused! She still takes 10-12 Percocet per day as she says her Dr says they have had no affect on her kidneys. I think she may have a serious addiction but how do I help her without upsetting her.

  32. I have been battling Lymphoma cancer for nearly 4 years. When First Diagnosed I was told the Tumor was attached to my Carotid Artery and Surgery wasn’t an option that my Oncologist said I would live 6 months or less with Radiation or Chemo. I chose not to do the Radiation or Chemo and have been taking Percocet for the past 3 years I started with Rybix or Tramadol to begin with. Now that I am nearing 4 years the tumor has gotten significantly bigger and the 10-325 Percocet do very little to relieve the pain. I do use Lidocaine as a topical pain relief but it only last 30 minutes or less. I have taken the natural medicine of Burdock root or Gobo Root along mixed with eating Aloe vera plants as suggested by an Asian Dr. from MD. Anderson along with uncooked raw honey. No one can believe I am still alive. It is not easy to do much of anything anymore as I try to be positive and not have family worry about me. The pain is gotten to the point of being unbearable, leaving me throwing up. I do take Klonopin now along with the percocet but I always eat something and never take it at the same time. My question is there anything stronger that I can take to help ease the pain. The pain is constant, burning, pins and needles feeling, I have had bleeding from my inner ear and throat in the past 6 months. I would like to find something to relieve the pressure of the burning, stinging, raw throat, constant pins and needles pain that I have.

  33. I was prescribed oxycodone 10/325 on feb 29 2016 for chronic pain. Now I take about 5 to 6 pills a day .. Becsuse it takes the pain away completely. I drink a lot of water through out the day because I get thirsty and I get hungry a lot. I know it’s only been 3 weeks but I’m scared that my liver is damaged. Not only do I have pain on my right lower back but I can’t stop taking the pills ..I flushed them down the toilet becsuse I realized I got addicted to them in just very little time. I am withdrawing from the pills. I’m concerned please help

    1. Hi Oralia. I suggest you speak with your doctor or a pharmacist about your issues. You may consider consuming some over-the-counter medications, teas and home remedies to ease withdrawal symptoms.

  34. I’m still scared about taking Percocet 10-325 3times a day I get anxiety attack thinking I’m gonna get hooked but I have arthritis in my spinal area an need it please help relieve my nerves my doctor an husband are saying I’m paranoid an over thinking

  35. Hi just wondering, My fiancé got her 4 wisdom teeth removed. She was prescribed Emtac (Tylonal 3 with no Caffiene) They are not working very well. So she is taking 5mg of percocets. Just wondering if it is safe for her to take over 4,000mg of Apap?! As the pain is not being contained. Don’t want her to hurt her self. But also don’t want her to overdose. Last time she took 2 Percs was at 11pm and 2 Emtecs at 9pm it’s 330am now (next day) can she take a couple Percs to sleep?

  36. my doctor ordered Percocet 10/325mg THREE TIMES A DAY. I NEED IT EVERY 6 HOURS. ITS 3am and I am awake because of bilateral leg pain…..I took one at 9:40pm. NEXT ONE DUE NOW!!!!!

  37. I take up to 40 10/325 in a day and have been doing nearly everyday since April 2015 and havent stopped taking that much to this day. and I don’t see and end to it. sometimes I can take up to 60 10/325 in one day and then limit back to 40 the next to prevent an overdose. I’m still curious about the acetaminophen overdose because if I take 14 plus grams in a day for a year straight, and only had 15 days thorought the year span that I haven’t taken that much. how am I still alive if said overdose of acetaminophen was possible. and I haven’t had any liver damage signs to my knowledge I haven’t talked to a doctor yet. mainly because I’m afraid to see what the damage is. what exactly is the limit for apap? and if I were to quit what would long term withdrawals and symptoms be for this kind of limit of percocet and apap?

    1. Hi, Bib. We’re here to help you, not to provide with lethal dosage. Please reconsider what you are planning to do…think about your family and friends. Remember you are not alone!

  38. Victoria…dependant yes! 1 pill a night I wouldn’t call an addiction, but I would say he has become physically dependant on the nightly dose, his body expects to have it and by not taking it, it causes wd symptoms. But shouldn’t last very long being that it was one pill a night, how long has this been his regimen? If years then maybe wd will take a week or two, otherwise should feel better in a few days

  39. My son in law had open heart surgery and when he came home my daughter insisted he stop his 1 Percocet at night as he did not need it. He took 1 at night for 2 weeks. Now he has stopped it but acts like he is having withdrawals, as my daughter convinced him he was addicted. Could this be true was he addicted on 1 pill at night ?

  40. Last night my husband took two Percocet 5/325 and three Aleve pm for his pain and sleep. I would like your opinion of that dosage please.

  41. My boyfriend has been taking hydrocodon 10-325 for over 10 years. 1 Pill every 4 to 6 hours as needed for pain. In the last 4 years, he will eat up 100 pills in 5 to 6 days, then he will be without for the amount of time before the script can be refilled. We go threw the same routine every week.. anger and vomit and mean and sleeping non stop or doesn’t sleep at all for days. I used to hide a few pills for him, but he always found them, no matter if they where in the bottom of a tampon box or folded up in the sheets. I was put on pain medication for back problems and can’t hide mine fast enough. 80 Of my pills had been taken along with 100 of his…. I spoke to his doctor about my concerns and since his liver test came back fine, I was told to mind my own busniess…. he told his doctor I lied and he had plenty of pills left….

  42. cousin took 25-10/325 Percocet at one time to get high. He lived and everything seems ok he did this over a year ago, he is young and I think he thinks he is cool for doing it he talks about it occasionally. it worries me bad I love him and don’t want to lose him please advise. I also know they were not his he bought them at a concert and eat them up to see how high he could get.

  43. My wife has been on perc ocet since May of 2014 after a knee replacement. Is that to long and she goes to the pain clinic monthly.

  44. I don’t even want that garb with Tylenol gimme the good shit not the opiate naive kindergarten school kid stuff some fent lolly “actiq” with some iv versed

  45. Is it safe to take Percocet while on morphine continuos. And what is the safest dose of Percocet if you are on 30mg of morphin every 12 hours. Thank you

  46. My daughter is taking 10 – 12 percocets every day and has done so for six months now. I am so worried about her. I believe this is way too much and I don’t know how she will ever be able to come off of them. Obviously she has an addictive personality and keeps telling me not to worry that it is ok to take the amount she does. How can I help her?

    1. Hi Susan. You cannot not worry. Is she prescribed the Percocet? If she is, but taking it in doses higher than prescribed and more frequently than she should is illegal just as taking medications you do not have a prescription for. If she thinks it’s not that bad – she’s in denial, while maybe loosing the control over taking Percocet. If she refuses to quit or see a doctor, you can arrange addiction treatment for her and put her in the hands of professionals.

  47. My husband is prescribed 120 Percocet by his Dr per month, these pills last him approx 2 weeks, he is buying them off the street the other 2 weeks each month, he is also an alcoholic, he drinks 18 beer every day, I have threatened to leave him if he don’t get help, my threats are useless, how long can he go on living this way before it starts to affect his health

  48. I am prescribed 5/325 percocet I take two at a time, how long should I wait to take two more? Is it four or six hours? It doesn’t say on my bottle.

    1. Hi Jade. The usual adult dosage is one or 2 tablets every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams. Ask your prescribing doctor to be absolutely sure you are taking it as prescribed.

  49. Hi, im 140 lbs and i took two more Percocets about 3 hours ahead of schedule since my pain came back. Im really worried i may have caused damage to myself.

  50. i have just had should replacement and taking Percocet 10/325 every 4 hour as per doctor.
    The pain relief is limited some times , can I take an extra Percocet once or twice a day
    This is all about my pain levels
    Thank you for your input

  51. Hi I’m all new to this vhst site stuff but I read a lot of what u guys have to say and thank you. But I have a question but first let me tell u I have been on 15 and 30 mg perks for about 4 years now and I don’t feel anything getom them. Is there anyone who would know some ways to help me. Mind you I have tried many ways to do this but nothing has worked unless I may have done them wrong. Hopefully someone out there has a solution. Thanks n advance.

  52. Hey all, Wednesday afternoon I got back surgery. Fast toward to right now I’m in moderate-severe pain as expected. I was given oxycodone 5/325. I started taking 1/5hrs but now I’m taking 1.5/4hrs. Blown away by how much they reduce my pain would I be setting myself up for another health issue?

  53. I am currently taking 10/325 Percocet for a bad back, broken foot in two places and other ailments accosiated with chronic pain. Why is it now so hard to get a prescription filled. I live in las vegas and my Wal-Mart is now two weeks behind. Any similar stories and or experiences?

  54. listen everyone I’m 21 years old I have been on 60mg of morphine 4 times a day plus Vicodin since I was nine years old they had to put me on that I have probably the worst case of polyticular arthritis which means the entire body a hip replacement and at 13 I was diagnosed with discoid and systemic lupus that will kill you it burnt my entire body I was in the icu so it depends on your pAin tolerance when you been on pain medication that long it starts to wear off it stops working so they have to increase it not because ur a addict because u have a high pain tolerance,!!!!

  55. Hi Jim. You can Call the Poison Control Center at 1-800-222-1222 for a free over-the-phone assessment of the risk of overdose. Then, they’ll give you further instructions for any necessary actions. Hope you are OK!

  56. I took three 5mg tablets at nine thirty am and then three more at about two thirty pm and on more an hour later. I was feeling fine but I got pretty nauseous and threw up everything I had eaten that day. Am I risk of an overdose?

  57. Hi Moore29. I have to say it is quite a high dose. Can the doctor prescribe some other, more powerful medication to help him with the pain?

  58. My husband is 323lbs and 6’2 ..he was recently shot in his forearm…long story short he had surgery Friday and the pain has gotten worse because the bullet fragment is no longer laying on his nerve and now his nerve is stretched and damaged. He was prescribed 5/325 percocet..1 to 2 tabs every 4 hrs…well the pain has gotten worse (the Dr said it would for the next week) and my hubby is now taking 3 pills every 5 hrs…is that safe? He’s in ALOT of pain otherwise..thx in advance

  59. my mother is taking a high does of percoret daily and about 8 to 10 per day. Can that effect her mental thinking to make legel matters?

  60. Advice such as to tell someone thats not that experienced in this field is not good either. You suggested that he stop to see if he has any w/d symtoms? Thats so wrongful doing. Under no circumstances should he stop his percocet to see if he starts to experience withdrawal. It takes him off the dosing schedule and puts him at risk for withdraeal symtoms and the pain clinic agreement specifically states in many if not all of them NOT TO STOP YOUR MEDICATION WITHOUT CONSULTING YOUR DOCTOR FIRST NOT EVEN A PHYSICIAN ON CALL MAKES THOSE KINDS OF COMMENTS TO ANY OF THIR PATIENTS

  61. I have a friend that cannot swallow pills so they give her percocets to her in capsules so they can be opened and poured on applesauce or straight on the tongue. Yeah I know how it works. My comment on percs WHY HAVE THEM IF THEY CAUSE MORE PROBLEMS THAN HELPING. I DIDN’T SEE ANYTHING ABOUT THE PATIENTS THAT CANNOT SWALLOW PILLS. THEY DON’T MAKE A LIQUID FORM WITH THAT STRENGTH.

  62. Hi Tony. Speak with your prescribing doctor about your concerns; it’s possible that you can take drug tests to monitor levels of oxycodone in the system. One REAL way to know whether or not you’re dependent, though, is to stop taking Percocet altogether (with doctor’s knowledge and permission) and notice whether or not you experience withdrawal symptoms.

  63. I take Percocet 5/325 or 10/325 just one tablet at bedtime 3 to 4 times a week to help me sleep due to extreme hip pain . How long can I do this without becoming dependent ? thanks


  64. I have been doing some research about all the prescriptions my mother takes. I just downloaded her prescription history for the last year and was shocked to see that her doctor prescribes 300 325 mg a month for her. That’s over 4,500 pills since last May. Not to mention the 90 pills of lorazepam a month. In all the research I’ve done I’ve never seen this amount ordered. This has been happening for at least ten years. She has agreed to go to rehab after two hospitalizations in the last 15 days. I am thinking about taking legal action and wondering if it’s futile or if maybe this doctor is responsible in part for the addiction. Please help!

  65. Hi Jesse. Percocet contains acetaminophen, which in higher doses can damage the liver. Since every organism is different, noone can tell for sure if you are facing risks of liver damage and/or liver failure. But you can look out for signs and indications. If you are experiencing nausea, vomitting, yellowing of eyes and skin you should see a doctor.

  66. The generic oxycodone manufacturers have been changed by all the pharmacies…no more of the popular Watson and Malinkrodt are being supplied to pharmacies. Instead new brands like Actavis, Amneal, and Alvogen are dispensed by all high street pharmacies.

    This is a DISASTER for patients. The new formulations simplyvDO NOT WORK of which Actavis a333 is the worst with side effects. I have been in pain management for three years and I am in no doubt whatsoever that this is due to action taken by the federal government be it the FDA or DEA, to illuminate the prescription drug abuse and overdose epedemic widely reported in the USA. But it is at the cost of denying PATIENTS who genuinely need these meds for thier healthcare. Its a sneaky way of removing opiate meds without having to publicly announce it.

    The evidence is everywhere in many many complaints from patients since Jan 2014. What can we do….our doctors continue to prescribe thier patients pain meds, the pharmacies fill them…but the patient is left holding the expensive bag and in pain. Some may say..oh you just got a bad batch..or its your tolerance that’s increased..but come on…every pharmacy that has dispensed Watson and Malinkradt for years suddenly change suppliers at the same time..and so many patients complain. I never had a single issue before. I can only hope that enough voices are heard to effect authorities to allow the original formulations to be supplied….but still controlled without denying the meds to the patients that genuinely need them.

  67. Hello Liz. Percocet is considered CNS depressants, so it will react with alcohol in a similar way as depressant drugs react with alcohol. In addition to sedation, it may inhibit the coughing reflex, which places an individual at high risk for aspiration, pneumonia and choking. This creates a dangerous effect that could stop breathing altogether.
    Adderall, on the other hand, is a stimulant and many people make mistakes when thinking that mixing alcohol and adderall all together will even them out. Adderall seems to overide the effect of alcohol, making the person feel as if they can drink more without getting drunk, eventually leading to alcohol poisoning.

  68. I have been taking Percocet 5/325 one tablet everyday for the past 15 months… Half in the afternoon. Half in the evening. I am also taking three 10mg adderall a day for 3 years now… Am I at risk for any problems? Even after a few drinks? Thx

  69. I have a friend who always ask for my 7.5 milligram percocet. It’s at the end of my prescription and I am out of 30 of them. I now need my meds and my doctor is not wanting to refill my prescription. What do I do?

  70. Well I have very bad toothaches every once in a while and today I’m having one of those tootheaches I have already taken 3 5-325 mg of percets I know I spelled that wrong but I’m still in pain and its been 2hours can I take another one please answer cause I’m in some much pain

  71. Hello Mary Jo. If you are taking Percocet as prescribed, you are not abusing it. However, if you take more Percocet more often than prescribed, or in ways other than prescribed … use = abuse.

    Your body may become dependent on Percocet (oxycodone) and need the drug to function normally. But dependence is different than addiction. It is a physical manifestation brought on (and expected by doctors) as a result of regular, daily dosing of Percocet.

    Does this help?

  72. Please can you tell me if 2 Percocets (10-325mg) per day ( taken at HS to sleep because chronic diagnosed pain keeps me awake), is considered to be abuse or addiction. I do not take any more than 2 for pain control even when my pain is bad during the daytime.

    Mary Jo.
    Thank you so much.

  73. Hi Tonya, I have been taking 4-, 7.25 mg of percoset a day and have no side effects from taking
    it. What to remember is the amount of acetaminophen is in each tablet. You should not take
    more than 4grams of acetaminophen in 24 hours. That’s the rule of thumb. If you take more
    than that, be careful because you could cause liver damage that is permanent. And you can’t
    live without a liver!

  74. Is it dangerous to take 7 5mg percocet in the course of 24hrs if you’ve developed a high tolerance over 2 years?

  75. I got a message that there was a reply to what I typed, I cannot find it. Maybe it wasn’t something that I needed to hear today. I just picked up my script, I am doing fine. I keep myself to the 4 a day I am supposed to take and surely need. I got out of bed this morning and needed a pill really badly. The pain was right in my face! It does seem to be more painful since I started taking the Percs, I don’t know why. I will try to push ahead and continue with church and my fellowship of friends. I think the right answers will come to me one day. I don’t know that I am doing anything wrong you know. It is confusing. I think it is because the custody courts are in it. The ex’s lawyer is making me out to be a big bad drug addict. I have control and am a good father. Everything is so confusing to me right now. I will continue to pray about it!

  76. Been on Pain meds for years. Started with Lortab 7.5/500. I was happy with those meds but my doctor stopped scribing them cuz of the tylenol. He went to percocet 10/325. I guess these take my pain away too. I haven’t really been to concerned about my liver. I guess I should be, I drank a lot up until 5 years ago. None now. I don’t know if the liver heals itself from alcohol damage during time taking pain meds. I wouldn’t think so. I think my family has pretty strong livers, they all were drinkers and none have had liver trouble. My dad did, scerocis. SP? He lived 15 years with it and even drank with it and died from lung cancer. Funny how that works. Kind of hard to get off pain meds after taking for 15 years. Non-narcotics dont’ seem to do much for my pain. Tried all of them. Ex girlfriend is tryying to take my child custody rights away from me because I take pain meds. They have never affected my ability to be a good father! I think the courts will have to see that! I have seen multiple doctors and one that I seen one time suggested that he thought I had a substance abuse problem. Now, that is only one opinion out of all of the other doctors I have been in contact with including my current physician. I think it is a no brainer. Now, she is trying to get me for child abuse, I didn’t do anything. I think she is desperate. I am a great father. Been without my baby for 9 months. Could be a real easy time for me to abuse my 120 perks/mo. I am not abusing them though. Life is so confusing.

  77. Hi Marci. You’ve probably developed a tolerance to Percocet after daily dosing…but you don’t really want to increase your tolerance to oxycodone by increasing doses from 15 to 30 mg. If you do, you may experience withdrawal when returning to 15 mg.

    Speak with you prescribing doctor or a pharmacist about the mix-up; depending on the release version (immediate or long term release)….it may be OK for you to split the 30 mg into two 1 mg halves. But you’ll need medical supervision and an OK before doing so. Otherwise, you may need a prescription renewal to get the correct 15 mg dosage you need.

  78. I normally take 15 mg percocet every night before bedtime. My husband takes 30mg. He left for a month to go back to work taking my 15 mg percocet with him. He left his 30 mg pills here. Would it be safe to take one of his at night until he gets back?

  79. I take 1 10/325 oxycodone every 4-6 hours as prescribed. Is it going to affect my liver or health if i continue this schedule for longer than 2-3 weeks?

  80. Hi. I’m currently prescribed 40mg of oxycodone per day and i’m still having increasing pain issues. My doctor is recommending an increase to 50mg, so I’m wondering what is considered a high dosage per day. I’m a little worried that this will become a trend the longer I take these meds.

  81. Hi Val. You can tell her that normal dosing is no more than two Percocet tablets taken every six hours. 20 Percocets is a call for help. Good luck with the intervention, and let us know if we can help further.

  82. My friend took ~ 20 Percocet. I called 911 and they reversed the ocicodin. I told her she could have killed herself with that dose and she keeps saying no. I am going to be part of an intervention in a couple of hours and I would like to tell her the lethal dose of Percocet. Would someone please answer me soon. Thanks.

  83. Hello Richard. It sounds like your body has developed increased tolerance for the pain relief effects of Percocet. While you might try to reduce dosage in order to increase it again, you might bring on withdrawal symptoms that are uncomfortable. I’d suggest that you talk with your prescribing doctor to report the tolerance (it’s a totally natural phenomenon) and to discuss alternatives you have. Ask about the medical practice about decreasing tolerance for some time, and whether or not this is clinically advised. Also, seek an opinion with your local pharmacist about this practice to come to your doctor’s office prepared!

  84. I take 2.5 3.25 of Percocet as needed for cronic pain usually every other day and codeine with tylonal on other days. I try to keep Percocet to minimum so it will continue to work without increasing doses. But pain is getting worse as time goes on. I’m 61 and want more relief but fear that too much will lead to reduced results and that thought is very discouraging. I can’t find anything that will tell me how much to take to insure it won’t stop working. Something like taking for a few days then, stay off it for a few days to let it get out of my system. I really would like to take one pill a day before I excercise to help with the pain. Any source of information you can direct me to?

    Thank you

  85. Hello Debra. You’ll need to consult with your physician and get clearance BEFORE upping the dose. Call in for a consult on the phone and to report increases in pain, but please don’t increase doses of your pain medication without medical supervision.

  86. I’m about 120 lbs and am on Percocet for pain caused by a bulged disc which is hitting a nerve. I just increases from taking two pills at about 7 AM, 2 PM, and 9PM. I am getting worse dealing with the pain and for the last few days started taking 2 pills 4 times throughout the same time period.

    My question is, is this too much?
    Thanks, Debra

  87. Hi Denise. These are very specific questions that might be best answered by a pharmacist and a medical review officer at a drug testing facility. I’d suggest that you try your lcoal pharmacy first by phone or walk in visit. And then, call a drug testing center for clarification, if needed.

  88. how many nanograms are supposed to be in my system if i am taking 10 mg oxycodone for 3 years?also does the instant release leave your system faster ? i have been searching for the answer with no luck,please help.

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