Mixing Tramadol with alcohol

Effects of mixing Tramadol and alcohol include drowsiness and relaxation. But mixing Tramadol and alcohol can calso cause shallow breathing and slowed heart rate. Or you can die from Tramadol overdose. More here on harms and warnings for mixing Tramadol with alcohol.

minute read

Thinking about mixing Tramadol with alcohol? Know what can happen.

How much Tramadol can you take at once? It depends on your opioid or opiate tolerance, but doctors start opioid naive patients on 25 mg no more than 4 times a day (100 mg total per day).  But the main danger of mixing Tramadol (an opioid medication) with alcohol is their unpredictable depressant effects. Learn what happens in your body when you mix Tramadol with alcohol and what can go wrong. Plus, we invite you to ask questions about mixing Tramadol and alcohol in the comments, at the end.

Tramadol and alcohol effects

Tramadol is a pain relieving medication that can also cause feelings of euphoria and sedation. Some people like to enhance these euphoric effects (the feeling of getting high) by mixing Tramadol with alcohol. From self-reported experiences people have reported some of these Tramadol and alcohol effects:

  • drowsiness
  • euphoria
  • hallucinations
  • numbness
  • relaxation

Is Tramadol addictive? Yes.   But this isn’t the main danger of drinking while on Tramadol.  While alcohol can intensify the euphoric effects of Tramadol, users have also reported negative and frightening side effects as well. Tramadol chemically reacts with alcohol, having an additive effect in the body and brain when combined. That means that the central nervous system depressant effects of the alcohol and Tramadol are intensified when taken together. But slowing down the central nervous system is dangerous and can cause a potential overdose.

Dangers of mixing Tramadol and alcohol

When alcohol is taken with Tramadol it can cause dangerous side effects to occur. This is mainly because mixing alcohol and Tramadol can intensify the depressant effects of both alcohol and Tramadol on the central nervous system. Some potentially dangerous effects of mixing Tramadol with alcohol include:

  • dizziness
  • drowsiness
  • impaired coordination
  • loss of consciousness
  • nausea
  • overdose
  • shallow breathing
  • slowed heart rate
  • vomiting

Note here that this additive effect goes both ways – the Tramadol you’re taking also enhances the effects of the alcohol itself. Alcohol makes you sleepy, drowsy, and lightheaded. This is why drinking and using Tramadol can cause trouble concentrating, difficulty with coordination, and a slowed reaction time, all of which can cause accidents. Tramadol also heightens the intoxication you experience from alcohol, which can be potentially deadly or at least increase your risk of alcohol poisoning. In fact, you won’t be able to tolerate the same amount of alcohol you normally drink safely while simultaneously taking Tramadol.

Tramadol and alcohol overdose

It’s probably a good idea to avoid taking Tramadol and alcohol together on the same day. Why? Your risk of overdose on Tramadol directly increases when combined with alcohol. The effects of both drugs are much stronger together than they are separately. This is the reason why doctors recommend never mixing Tramadol and alcohol.  And although Tramadol overdose amount depends on your exposure to opiates, doctors start opiate naive people on doses of 25 mg of Tramadol no more than 4 times daily.

Tramadol and alcohol deaths

Alcohol is one of the most common substances people abuse in combination with Tramadol, and it can cause death. Even normal doses of Tramadol combined with alcohol can cause breathing problems or other serious issues. And if you abuse Tramadol (chew/crush Tramadol, snort Tramadol, inject Tramadol, etc.) or take more than a normal prescription dose, you might overdose. The only way to avoid these risks is to decide not to drink at all while on Tramadol.

Is it safe to drink on Tramadol?

No. The FDA warns against mixing the two at all. Mixing Tramadol and alcohol enhances the most dangerous effects of both drugs. If you’re not sure how far apart to space a prescribed dose of Tramadol and a drink, ask your doctor for more information on taking Tramadol and drinking safely.

Mixing Tramadol alcohol questions

Do you still have questions about mixing Tramadol with alcohol or other substances? Do you want more information on avoiding problems while drinking and taking prescription drugs? Please leave us your Tramadol use questions here. We try our best to answer all legitimate questions personally, and promptly. And if we don’t know the answer, we will refer you to someone who can help. Your experiences with mixing Tramadol and alcohol are also welcome.

Reference Sources: NIAAA pamphlet: Harmful Interactions, Mixing Alcohol with Medicines
DailyMed: Ultracet (tramadol hydrochloride and acetaminophen)
PubMed Health: Tramadol
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. My husband is a registered alcoholic and been given 50gm of tramadol for a fractured spine which he has to take 2 tablets 4 times a day is it safe

  2. My doctor has prescribed me 50mg Tramadol twice daily and 30mg Mirtrazapam once nightly. I feel awful the next day,he knows I’ve been on two 20mg Temazapam for years, first it was 5 mg Temazapam because I suffer from severe Ansomnia, then increased ton 10mg , then 20 mg, two 20mg tabs.at night I feel this is a vicious circle and my GP is not addressing the underlined problems.
    What can I do, I feel desperate now, as I don’t want to be on these drugs. I’m 72 and I know I can’t sleep without Temazapam. But what can I do?

  3. My husband has been un ultram for 3 years with no real side effects. A couple of months ago we found ourselves alone in the house for the first time in years without the kids and for some reason decided to drink a bottle of vodka together. My loving husband and best friend of 8 years lost his mind and I thought he was really going to kill me. He hit me, he choked me, he came after me with a fireplace poker. He has NEVER even raised his voice to me or our children. Something changed him and I was terrified of the love of my life. The worst part is how depressed HE was about what happened, it broke my heart to see him crying so much and having so much guilt over this.
    This is my experience with mixing ultram and alcohol. Please people don’t do this.

  4. the tramadol is about as potent as irradiated raw foods. -the alcohol is what mad it active. believe me i know. i can’t say ‘the alcohol’ as have only ever consumed bier/real ale & ONLY then did this ‘omni-potent’ product come alive. i was having 8 a day @ 50mg & the pain relief is barely worth mentioning. it was only when i re-consumed my 4 500ml of 5% quality German bier did the relief from terrible pain subside….. they’re about as potent as codeine! (2% morpheine ) ….. an expensive joke. …nb. the ‘other ingredients’ caused me night sweats, nightmares & in the case of tramadol – night terrors. better to bear the pain & take a slug of whiskey.

  5. For back pain and sciatica I take 4- 50mg of Tram a day: it helps me WALK and function normally daily. Especially good for sciatica. I do drink wine nightly WITH my last Tram of the day (50 mg). No problem. Only once I took double dosage and fell losing coordination and brusing myself and dragged myself to bed. I do not recall any pain or much recall of this one time incident. However, it did impress upon me the dangers of taking MORE than prescribed. As a senior falling is NOT to be taken lightly. Hope this experience is enlightening to those whom do drink with Tram. As for hard liquor; I do not know as I only drink wine (11% alcohol). Wine enhances the sleep w/some meds.

  6. Hello, a friend of mine had a very large amount of alcohol and tramadol
    He’s NOT OKAY he keeps on saying nonsense and imagining things that never happen he even tried to commit suicide yesterday I really wanna know what to do is he gonna recover or this will be permanent, been three days like this I really need help

  7. Tramadol does not give me a high for chronic pain. One botle of wine does. I take them together in the evenings plus gabapentin and clonazepam to sleep. Works for me

  8. hi,
    I suffer from painful knees and my doctor has prescribed me tramadol even though I told him I am alcohol dependent and drink about eight or ten pints of premium lager every night, is this ok ?

    1. Hi Ian. Mixing tramadol with alcohol may cause serious damage to your health. I suggest that you consult with your doctor about this.

  9. I take 250 Mg of Tramadol per day. I had some anxiety problems a week ago and decided to buy some beer to relax me. I bought 2 quarts which I drank that day. Haven’t drank any alcohol in a long time. The following day when I got out of bed I almost fell over. I had no balance and was very dizzy. The problem is this has persisted for over a week now. should I go to the emergency room. I have a very difficult time walking and would need to get to a bus stop to get me to the hospital. I tried cutting back on the Tramadol but that doesn’t seem to help and have not drank any alcohol since then.

  10. Is it safe for me to have a couple of glasses of wine after taking 50mg tramadol 7 hours ago please reply many thanks!

    1. Hi jETT. Please use tramadol only as prescribed by a doctor. Mixing tramadol with alcohol may be very dangerous for your health.

  11. I took a tramadol on Saturday it’s Tuesday and I’ve been shaking and becoming hot and cold and now
    Have a 99.8 fever can you help at all any at home remedies

  12. Had back surgery in aug of 2016
    Take 2 50 mg am and 2 50 mg at bedtime but trying to get off today I took 1 50 mg this morning can I have a couple beers and I won’t take another tramador till 1or 2 in the morning

    1. Hi Pat. Yes, it was more than 2 days ago when you posted this Q. You should be safe to have a beer.

  13. the 1st 5 effects from mixing tramadol with alcohol seem rather desirable to me!
    nb. i’ve found its bier that makes these pharmaceuticals come alive-(particularly real ale) – as they all seem very impotent to me yet designed-to have massive side effects-so 1 has to go back to c their GP 4 MORE drugs

  14. I’ll be honest, I’ve had 1150mg of tramadol (23x 50mg caps) over the last 4-5 odd hours, plus 12.6g of Pregabalin/Lyrica (42x 300mg caps). I started these prescriptions for severe back pain that turned into addiction after I dropped Targin/Oxycodone and Codeine, which gave me an extremely high opioid tolerance (I used to take 600mg of codeine daily – its available over the counter without a script here in Australia).
    I take this amount regularly…. What sort of damage is this doing to my body?

    Also, I never drink on tramadol. I did ONCE, and completely blacked out. When I woke up I found out I’d been a rude asshole and party animal to everyone, so never again.

  15. I’ve been taking tramadol for a disc prolapse since December 2016. I now of my take one 50mg capsule per day in the evening before bed. I’m going on holiday on Sunday for a week but haven’t taken alcohol since i started my treatment. Is it safe to have a few glasses of wine with dinner on this dosage?



  16. I’ve read alot about side effects, maybe they’re doing too much. Ive done them on alcohol plenty of times, the other night while drunk i did a 56 mg and a half of one and felt absolutely fine.

  17. I was visiting a close friend who is dying. His partner offered drinks and I stupidly took it. Over 6 hours I drank 8 doubles of vodka. Needless to say I have felt ill since. What can I do to feel better?

  18. Yes My Question is that I drink a tramadol Pill in the morning to be exact about 7:00am and drinker a Bud Light Straw-ber-Rita about 1:30pm which is about 25 0z and now I’m filling nausea..Now Iwant to know whether I should get medical attention for the nausea or not.Thank You

  19. I take tramadol purely for the chilled out feeling, got nothing wrong with me, just find it better than Xanax to cope with a suicide, guess I’m a little addicted now tho, been drinking every night on them for months now and no problem at all, so don’t stress over having a few drinks, you’ll be fine ?

  20. hi; ..erm has this advisory been published for very weak people-or am i unique?.. i am a 51yr. age male; weigh 10st. 7lbs; strict vegetarian for 25 years, eat once a day in the evening -cept occasionly a piece of fruit mid afternoon. i have had 2 prolapsed discs for 6months now-for the 1st 3 months suffered badly-zero painkillers-1 of the discs is rippled & pressing against the sciatic nerve.it was constant 24/7 discomfort, pain & agony. after an mri scan revealed what was what – i managed to get tramadol prescribed @ 50mg. well i started with 6 a day-then withdrew to 4 a day -the contents emptied out of the gelatin capsule & i put into a dbl espresso coffee-as the caffeine in it drives substances into one’s cells by up to 47% 1 more with a cup of tea in aftern. & the last 2 in strong biers-up to 5 biers @ 5-6%alc 50ml-just under an english pint….in the evening. all with 500mg paracetamol to give that 25% extra boost..& each time on a totally empty stomache for maximum uptake….after bodily adaptation i started to add 8mg codeine too. then 15mg codeine, now 30mg codeine –all with the tramadol,500mg paracetamol etc, strong biers in evening & i feel well, fine, very fine. the relief from 3 months of agony was like a god send…of course-eventually i am going to have to face ‘the-horrors’-few can handle & the emergency services are often called by most;… but i’ve been thru 14 bouts of these terrifying; tormenting horrors-siezures often happen @ their climax…so be prepared-keep plenty of mineral water & lemons & oranges around-believe me-they have saved my life numerous times & be prepared to be dripping in sweat & have zero sleep fo up to 7 days/nites.along with EXTREME anxiety-& there’s MUCH more……they certainly test one’s metal!!
    ps.swimming may well help to reset yor discs along with massage…

  21. I just started taking tramodol today. The last dose of tramadol I took was at 2:00 pm today (or technically yesterday). I did not take my 8:00pm dose, but did have two cocktails after 9:00 pm. I read waiting 6-7 hours should be safe to have a drink.

    Is it safe for me to take a dose of tramadol in the morning (8 or 9 am)?

  22. my partner takes tramadol and cocodamol for pain, he drinks at least 5 times a week and on a friday he can easily drink a full 70cl bottle of rum to himself. i were originally looking up about effects on moods as our relationship is unbearable just now. i dont like to see him in pain, he says he doesnt have a drinking problem either but i worry he is also abusing these pain killers and alcohol combination. i am scared to aproach the subject with him for fear of another outburst

  23. I want to know if I may regularly , depend on Tramadol, for pain, and abstain, for say- 24 hours, before a social event, where I might consume alcohol-and then return to Tramadol use , with no alcohol, after-say 24 hours ,later? Like -as in family holiday events-without challenging my health??

    1. Hi Jeffrey. Please use your medications only as prescribed by a doctor because you put yourself at risk.

  24. Hi – I just read thru all of the posted queries @ some experiences: he’s mine:& i’ll have to condense it; been drug free til age 50 {with the exception of sum standard prescribed over priced sleep tabs-weak) & bier…then due to 2 prolapsed discs in back pressing against sciatica nerve-spent 3 months in agony 24hrs a day with no let up-sleep was virtually absent. doctor refused to give me anything. probably thought I was bluffing as many do to spend a few months off work! eventually I managed to get codeine in the form of co-codamol @ 30/500mg paracetamol mild relief .wasn’t bad .but not good enough. I then managed to get 60 x 50mg tramadols-much better.(had 2 in morning-1 in aftrn. & 2 @ nite. yet every nite I mixed with 2-4 biers @ 6.5 % alc.(proper ale)..had an handful of nitemares but nothing compared to the pain had b4..also may I had along with my little evening little cocktail I also was adding a VERY potent hypnotic..(1mg put u out deep for up t 12hrs. overall I had a 80-90% reduction of pain. then all ran out & I went thru the usual 7 days/nites of the dreadful tormenting ‘horrors’ – (my 12th in a year) most folk wud need sedating. here’s just a few ingredients of the horrors: ZERO sleep not even a second-up to 6nites. up 2 the doubling of one’s heart rate. 24hr heavy sweats combined with shivers & shaking; much thoughts of death. dark nites of the soul to put it mildly; then @ the peak everywhere turns a different shade of silver & grey even the grass, trees, sky. everywhere looks dirty & low. & all 1 can smell is pollution. I can even smell the plastic from a distance that mineral water is cased in. great hearing enhancement too. a falling leaf could make one cry- let alone certain songs-if u could bare to put music on. a knock @ the door cud give u a heart attak….there are many more!!! to add. but hope this suffices. so remember: there is a price to pay 4 EVERTHING!!!

    I’ve 9 siezures in the past year too..so if u strong-u shud pull thru. but if of a weaker constitution….I’d use the old adage:i advise u strongly to keep things in moderation!! – I’m also still consuming same amount of mixtures of said substances & train regular with my weights & take a regular cup of that highly addictive chatterbox noxious legal drug ‘coffe’ in the form of a dbl espresso….after the 7 days of horrors of which must be noted range from mild to severe-depending upon the power of ingested substances one has been taking – you know you’re back to normal coz it feels nice .great.. to be alive again!!

  25. You should also be made aware that epileptics should never take Tramadol. Someone slipped some into my drink and I was lucky to survive. I had definitely 3, more likely 5, possibly more seizures and was lucky someone found me. It’s incredibly dangerous. 🙁

  26. Please I took two 50mg of tramadol and afterwards I took two shots of vodka before having sex with my girlfriend and I discovered I couldn’t get an erection at all! Please is it the combo of tramadol and alcohol that is responsible for my inability to get an erection? Pls I need an answer asap cos am scared!

  27. I am on tramadol for sciatica. Am going to a family party and would like to have a drink. When should I stop taking these tables before the party, so that I can ensure I do not get any side effect, is one day, two days or less. Thanks for your help, may just decide to not drink, but would like this info.

  28. I take tramadol 50 mg 3times a day. And I’m an alcoholic. Been drinking for years. Serious alcoholic!! Like 96 fl oz of 12 percent malt liquor daily.
    I know that’s bad but how dangerous?

  29. I am taking 200mg Tramadol daily for pain of broken vertabraes (2); I have a drink or a glass of wine daily before or with dinner, I have not had any eupheria (heigh) or other reaction to my combining both. Why have I not felt any side effects? I take the Tramadol in the morning early.

  30. Hi my husband is on 50mg of Tramadol 3 times a day also diazepan 5 mg three times a day and enantyum 25 mg three times a day for cyatica
    Last night he had two glasses of wine before taking the medication at midnight…
    He was in so much spasm pain at 6 am he took the Tramadol, diazepan and enantyum agian…
    He is now constipated and feeling very tired…
    The time now is 5pm and we have not taken any medication since 6am…….
    Do I need to worry

  31. My husband has been taking tramadol for at least 6 months. The doctor prescribed it when the Co codamol stopped working. He us disabled and in permanent pain due to a condition called Perth disease which he has had from birth. He has one leg shorter so walks with a limp.
    He also drinks alcohol every evening ranging from 4/5 bottles of beer and also some spirits ,this is every evening.
    Lately I have noticed a big change in him . It’s like he has a split personality. His temper is much worse and dare I say he us a bit paranoid.
    He has suffered from his nerves for years and is ocd. But undiagnosed. He is obsessed with routines and gets very upset if there are any spontaneous changes to his plans.
    I guess what I’m saying is he is clearly alcohol dependant and he does have border line mental health issues and is in pain from disability ,and now he is taking tramadol and has become a monster to live with.
    We are going to doctors tomorrow after I threatened divorce if he didn’t go. I’m going with him to ask if his med can be change.
    My worry is he’s way to far down the kine and will most likely suffer some very unpleasant withdrawals.
    Personally I think this drug should be banned. I have witnessed some extreme personality changes in folk that have taken it. He hasn’t been honest with the GP. About his drinking. He always plays it down . I’m at a loss as what I can do for him other than go with him to GP. Is there any thing else I can do

    1. Hi Ruth. These are serious problems. I suggest you speak with the GP, or even ask for second opinion.

  32. My husband has been prescribed tramadol in definatley as he has chronic pain due to Perth disease from birth.
    He also drinks every evening up to 4/5 beers and sometimes spirits aswell
    He suffers from anxiety but does not take any medication for it. He is quite a difficult man to live with as he has a very negative mind set. But lately I have noticed a big change in him with regards his mood.
    He has mood swings mist says and his temper is quite bad. He flies off the handle at the slightest thing. He seems to be 2 different people , the normal him and a very nasty him.
    Clearly he has a problem with the medication and alcohol but he doesn’t accept this at all. Discussing it will only cause more temper tantrums. I am at a loss at what to do . It is becoming a real problem .
    Am I able to discuss this with his doctor ?.
    He hasn’t been honest with the GP because he always downplays his alcohol intake but he drinks every evening . I think that taking the tramadol and drinking the alcohol is changing his personality and he is becoming more aggressive and more unreasonable. He won’t discuss it with me and I know he won’t admit to his GP that he’s dependant on alcohol.
    What can I do to help him .
    He is making home life almost impossible and I am considering divorce , but I don’t want it I want my husband back .
    Any advice would be appreciated .
    Thank you

  33. After breaking 4 ribs in a cycling accident 2 weeks ago, my specialist has prescribed 2 tablets of ULTRACET every 8 hours for pain. Each tablet contains 37,5 mg of tramadol hydrochloride and 325mg paracetamol. I drink 2-3 glasses of dry white wine every night. Am I putting myself at any kind of risk under these circumstances?

  34. Hoi.
    I’m a bit concerned about my liver.
    Since five days I stopped using Tramadol, but I keep experiencing negative aspects of the drug.
    I drank alcohol in the evenings with it, but since then I have no energy at all.
    Everything I do feels too much of an effort and is quickly too much to handle.
    I keep experiencing stress, while I don’t have any..
    Especially the first day I stopped using it I reacted very aggressive and angry to stress.

    I used it for only a few days, say four, and took from 100-150mg a day, after I had my tooth removed and went to the doctor for an alternative painkiller, because I found the paracetamol not to be effective enough.

    Now after five days without tramadol I still feel nauseous and lame..!

    I also noticed that I’m at the edge of getting a cold or flu.

    What’s happening?

  35. Hi I’ve just got home from a mates had 5 beers.
    I want a good sleep as I’ve been workin 16hours a day the past 7 days I decided to have 2 200mgtramadol tablets slow release as I have a bad knee injury.
    I’ve just started to read up on tramadol and am getting very worried about Nixon that amount and alcohol.
    Any feedback would be good.


  36. When i attend a social function i want to have some wine. Does that mean I cannot take 1- 25 mg. of tramadol before I go to bed to ease my pain???

  37. Hello, I am having problem with my breathe and pains in my back after I took multiple pills of Tramadol and drank alcohol in huge amount just to enhance my sex drive. right now I am having heart pounding like when someone is in shock. I have gone to the local pharmacy to seek help and they prescribed blood tonic and pain killer, though the back pains are reduced but I still feel drowsy and abnormally pause rate and breathe. please help me, I am dieing

  38. I have been taking tramadol for the last week and a half. Last time taken was almost 24 hours ago. Would it be ok to drink alcohol if I don’t plan on taking anymore tramadol. I guess I was wondering if the medicine has cleared my system enough not to have major interactions with each other.

  39. How many hours I shouldn’t drink alcohol if I take tramadol? Can I use tramadol 100mg on the morning and at night drink alcohol?

    1. Hi Ahmed. It is not recomended to dring alcohol while you are using Tramadol. Please consider that it is illegal to consume medications other than prescribed, and you put yourself at risk.

    1. Hi Donald. Usually, Tramadol stays in the body up to 2-4 days after the last use. So, please consider that it is illegal to consume medications other than prescribed, and you put yourself at risk.

  40. I made Hamaroids surgery and am taking tramdole as a pain killer..my question is it fine to take tramdole after drinking alcohol in 6 hours…please i need an answer am in real pain

    1. Hi, Tom. Call the Poison Control Center at 1-800-222-1222 for an assessment of overdose risk, or call 911 ASAP.

  41. Can you tell me why my body gets extremely sore, especially my back when mixing alcohol with Tramadol on a daily basis. My doctor is prescribing Tramadol and is aware of my alcohol misuse!
    I also take 40mg of propranolol, and 2mg of Diazepam and Mirtazepam all on repeat prescription and have been for 3months now, but i’m sweating extremely heavily constantly and having strange dreams?

  42. Oh sweet Jesus. My friend took 300mgs of Tramadol and drank 5 beers. He had a seizure, fell and hit his head on the sidewalk, got a concussion and needed 10 stitches on his scalp. It was a mess.

    My question is what is a safe time to wait after taking Tramadol to drink alcohol? 8 hours? 12 hours? 24?

  43. Unaware of the dangers of mixing transfix with alcohol, I did so last night and lost consciousness. When I eventually came around an ambulance had been called and I was throwing up everywhere. When is it safe to start taking my medication again? I still feel incredibly sick and my stomach is churning.

  44. A close frind of mine was drinking the other night and got alittle drunk. She went into a mental breakdown and swallowed roughly 20 tablets if tramadol with her alcohol. She slept the whole next day and then the second day she finally threw up the is smelly clear/yellowish liquoid. Do I need anything to worry about. It now has been 3 days since the incident. Is it to late to take her in to get checked out, she doesn’t want anyone asking questions. Should I just let it go, it’s been 3 days and she is still breathing so does that mean she is alright?

    1. Hello Kayla. Even though it’s been 3 days since the incident, I suggest you take her to the hospital only to be sure she’s alright. Also, she might do this again, so talk with her about her problems, or even suggest her to talk with a therapist. Often, early interventions can prevent situations from worsening.

  45. right this minute I have about 500 mg of tramadol in me, 900 mg of gabapentin, and a half of fifth of vodka, high tolerance. Don’t feel too bad at the moment.

    1. Hi JesseJames. Not a good idea! You may not be feeling any effects at the moment, but soon all three substances will be fully absorbed and in your bloodstream. I suggest you ask someone you trust to drive you to the hospital where they can pump your stomach for any undissolved pills and then address any possible risks.

  46. My husband is 53 years old has dual additictions main one alcohol he has been in two rehab in two years he was in the last stage of alcohol meaning if he would of not got help they only give him a year to two months to live so he went into this last rehab this time last year this rehab seam to work he almost made it 9 months then a Dr prescribe him ultram I have smelled alcohol on him a few times my question is could the ultram have woke up the side of the brain that craved the alcohol and if he hadn’t taken the ultram would he have not drank what are the possiblety of that

    1. Hi Cindy. Ultram use does not cause people to crave or go back to drinking. I do not agree with the doctors prescribing him medications while he should be sober and completely substance-free. See if you can talk with him about this and suggest he gets some support group or psychotherapy help before he goes back to drinking regularly again.

  47. my partner is 44, has been on DELUXOTEEN and TREMADOL for back pain and depression, she also drink a lot every day, I don’t know how to help her, if its at all possible. She is such a nice person but needs to know what she is doing will kill her

    1. Hi Steve. You are right, mixing those medications with larger amounts of alcohol is causing harm slowly but surely. You can try to talk to her and tell her you will support her to stop drinking while taking the prescribed meds. Also, counseling and psychotherapy sessions may help get to the bottom of what it is that is causing her to drink every day.

  48. If mistaken taken alcohol n taramadol together .. What will I do? And if more than a week and 2weeks nothing happen to me .. Do I need to be still worry? If mistaken taken Alcohol n taramadol together .. Did cause damages already or do I need to see doctor for it?

    1. Hi Ben. If I understood you correctly, you accidentally mixed tramadol and alcohol more than 2 weeks ago? If you are feeling no side effects or problems, you are OK. Just be careful not to take different substances together again.

  49. after taking 50g of tramadol i had 3 glasses of wine miced with lemonade,,afterwards i was freezing cold and i couldnt get warm, through the night i was up 4 times for a drink as i had a very dry tongue and this morning when i woke up i was sweating anf had a severe headache,n i was sent home from work due to feeling ill,,,is this down to the alcohol or have i picked up a bug????

  50. Hello, I was in severe pain this weekend and was already drinking quite heavily. I took a few tramadol to try and rid my pain. I was fine until a couple hours later when I blacked out and had no recollection of anything for about an 8 hour span. It’s now two days later and I still am unable to keep food down, and I have the shakes pretty badly. I now know how stupid my actions were, but obviously Cannot take them back. Any advice on how to feel better?

    1. Hi Gabby. I’d suggest you seek doctor’s help since you are facing great chances for dehydration after not being able to keep anything down for a few days. Ask your doctor and/or pharmacist to recommend medications or herbal remedies that can calm your upset stomach.

    1. Hi Ralph. You shouldn’t be taking any tramadol when you have had a drink. The medication may not be that strong, but different organisms react differently. Mixing painkillers and alcohol is not a wise idea.

  51. Hi. I have had 2 points of meth and two hours after I consumed two 50mg Tramadol capsules plus two 50 mg Tramadol SR (Slow Release) also marijuana. So 200mg all up. Are there any documented opinions out there as to whether this gets you high??

  52. Hello, I just had a single glass of wine (mixed with ice cubes and fruit punch) and my arthritis started bothering me. I generally take 100mg, but was wondering -very hopefully- if it would be acceptable to take 50mg instead.

  53. Started taking 400mg tramadol 15 april took my last dose midday 23 april will it be okay to drink alcohol on 24 april at 6-30pm

  54. I must have a constitution like an ox. I’ve had very unpleasant neck pain from musculo-ligamentous strain over the past week and took 200mg of tramadol tonight (kindly and unwittingly offered by a friend who suffers from chronic back pain). I then drank at least 7 glasses of wine and I’m writing about it right now. The tramadol did bugger-all for my neck pain and I feel exactly the way one would expect to feel after 7 glasses of wine. Mildly pissed. I often suspect the potential repercussions of mixing drugs with alcohol are grossly overstated to stop idiots from abusing them. However, the medical advice should clearly be adhered to, unless of course you have the constitution of an ox. Goodnight. I’m confident I will wake up in the morning and function as I normally do.

  55. I drink wine and beer. One or the other. I do not drink until the evening. I take Tramadol 200 mg once a day. Is this dangerous?

    1. Hello Dianna. It’s risky behavior mixing alcohol and tramadol and can be potentially dangerous. Doctors don’t recommend drinking alcohol for at least 10 hours after digesting any medication.

  56. Can mixing antidepressants alcohol and taking more than ur prescribed dosage of tramadol make you violent. Can you mix codeine with tramadol

    1. Hi Terry. Different people react differently under the influence of alcohol and drugs, especially when they are mixed together. Actually, mixing any prescription medication with alcohol is not recommended, but can also be dangerous.

  57. Hi Regis. As you already know, taking Tramadol and drinking alcohol is not recommended. Most people experience the side effects you described, as a result of taking tramadol in conjunction with alcohol.

  58. A family member has been taking Tramadol for a few years now to help her with severe pain in her back. While she’s been taking this drug she also drinks a fair amount of alcohol in the evenings. She recently has started to shake which is getting worse all the time. She also has lapses in memory and short blackouts where she doesn’t know where she is. She’s having problems with walking and even writing. She went in for a Cat Scan and an MRI which didn’t show signs of serious issues and we’re wondering if these effects may be caused by her use of Tramadol and perhaps mixing it with a few drinks from time to time.
    Any feedback you could provide would be greatly appreciated.
    Thank you,


  60. Hello N. Graytock. Thanks for your question. While it’s best to consult with a pharmacist for clearance and authorization for drinking and using tramadol, it seems to me (a layman’s researcher) that as long as the drink is metabolized (best to wait for 2 hours after alcohol consumption per unit of alcohol), the alcohol would be out of your system, making it a non-issue for taking tramadol. The problem usually occurs when people want to drink after taking tramadol…and then it’s best to wait at least the 4-6 hours until tramadol effects wear off…or longer, given the extended half life of the opioid.

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