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How long does methadone last?

How is methadone metabolized? Here, we review methadone effects on the body and brain, including the duration of action and routes of excretion. Then, you will have the chance to ask your questions about methadone or methadone’s addictiveness at the bottom of the page in the comments section. We try to respond to all legitimate questions or anyone needing help with methadone addiction with a personal and prompt response.

Methadone effects on the body and brain

Methadone is a prescription drug used to treat opiate addiction and dependence and/or for the relief of moderate to severe pain. Effects are mediated by opioid receptors in the central nervous system as methadone affects neurotransmission. But in addition to its medicinal use, methadone is very common a drug of abuse, abused for its sedative and euphoric effects. People who abuse methadone are likely to develop tolerance, become physically dependent, or psychologically dependent on methadone (How to treat addiction to methadone?).

Methadone duration of action

Onset of initial effects and the total duration of action of methadone depend on the route of drug administration. In fact, there are several ways that you can take methadone. Methadone can be orally ingested in tablet or liquid form or can be injected via intramuscular or subcutaneous injection.

After parenteral administration, onset takes place within 10 to 20 minutes. After oral administration onset emerges from half to 1 hour. When taken orally, onset is delayed, peak methadone concentrations are lower, but the duration of action lasts longer. After a single oral dose effects can last from 6 to 48 hours, depending whether the user is a chronic methadone user, or not.

Methadone time in the body

Methadone has an elimination half-life of 8 to 59 hours. Unlike other drugs, methadone has a wide bioavailability window varying from 40 to 99%. Up to 90% of methadone binds with blood plasma but after repetitive administration these number drastically change. Why? Because methadone has the potential to accumulate in the body tissue. Undergoing an extensive transformation in the liver to 9 metabolites, methadone is like almost no other drug.

Further, methadone is a synthetic narcotic and belongs under the Schedule ll of DEA controlled substances. As a prescribed medication, methadone is available in the form of tablets of 5-10mg, dispersible tablets 40 mg, oral solutions 1-2 mg/mL strength or injectable solutions of 10 mg/mL. When taken orally, methadone is rapidly absorbed from the gastrointestinal tract and is detectible in the blood within only half an hour.

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How long do methadone effects last

The duration of methadone’s analgesic action is usually between 6 to 8 hours. However, oral dose effects can last up to 48 hours, depending on whether or not the user is a chronic methadone user. Furthermore, there is a difference in duration methadone effects between intravenous and intramuscular injection. For example, following intravenous administration 10mg peak plasma methadone concentrations will be reached after 34 minutes. While after intramuscular injection of the same methadone dose will reach peak plasma levels 50 minutes later.

How long does a methadone high last

Methadone highs usually last for around 6-8 hours, but it is important to note that methadone can cause serious sensory and respiratory depression, depending on the dosage and route of administration. Peak respiratory depressant effects of methadone generally occur later and have longer duration than its peak analgesic effect, especially during the early period of dosing. The full analgesic effect of methadone is usually not attained for 3-5 days.

Methadone high effects

Methadone high effects are manifested in both psychological and physiological functioning. Among the most common methadone high effects include drowsiness, dizziness, mood swings and sedation, but methadone is one of the rare drugs that when administered in higher doses can cause depressed reflexes, seriously altered sensory perception and stupor. Coma is the worst case scenario but users need to always have in mind the high level of danger when abusing methadone.

The physiological symptoms of methadone effects include headaches, dry mouth, nausea, constipation, pupils construction and decreased heart rate. You can recognize when somebody is high from methadone by noticing the facial flushing and muscle flaccidity. Most dangerous side effects of taking methadone to get high include heart issues such as decreased heart rate. Furthermore, you may feel changes in your appetite, which will lead to weight changes, especially after prolonged use of methadone. You may also experience problems sleeping and decreased sexual drive.

Methadone duration questions

Do you still have questions about the duration of time methadone affects the body? Please leave your questions below. We do our best to respond to your questions personally and promptly.

Reference Sources: National Highway and Traffic Safety Administration: Methadone
Hazardous Susbstances Data Bank TOXNET: Methadone
U.S. Department of Justice/ National Drug Intelligence Center: Methadone

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119 Responses to “How long does methadone last?
Keith Wood
2:17 am April 19th, 2014

Hi, I was put on Methadone liguid solution at a MMT clinic and I am in phase one, trying to find the right dose for me. We went up by 5mg every 3-4 days and I got up to 25mg and at that dose it was working fine and doing it’s job of staving off the withdrawals, but it would not last for 24 hours, it was only lasting for 6-7 hours, so the raised me again, telling me I needed more in me to get my doses to start lasting longer. Well, when I went up to 30 mg, it greatly increased the length, but in the first 8 hours it was to much for me, I would naud off, slur my words, get dizzy, then around 8 hours or so later it came down to a level that I could safly walk, work etc. I thought Methadone had a long half life and it was supose to stay in you for 24-30-36 hours, so why doesn’t the 25mg last that long? 25mg is the right dose for me if it would just last longer than 8 hours. I can’t take 30mg because it is just to much for me until 8 hours or so later. My question is:
Should I just stick with the 25mg and in time it may start to last longer, or should I looking into asking my doctor about split dosing (i.e., taking 12 mg in the morning and another 13 mg in the evening) to get the 25 mg to last through a full day for me, because taking 30 mg at once is just not going to work for me and taking 25 mg doesn’t last for a full day. Really need some advise, I am in my 4th week of treatment, just started, and have tried 30mg twice and have had to drop, just can’t do 30mg comfortably even though it lasted longer, but 25 mg was perfect, but would not last longer than 8 hours.
Thank you for your time and advise

7:13 am April 19th, 2014

Hello Keith. Your prescribing doctor would have a better idea of your individual needs than us here on Addiction Blog. Have you brought up the topic yet?

Robin
1:48 pm July 4th, 2014

My sister in law after going to rehab and it not working says she’s going to a methadone clinic for the second time. I don’t know what her dose is every morning , but I want to know if I would be able to tell if she is high, off of methadone, or if she is back on heroine. Would there be a way that I would be able to tell??? She goes to the clinic in the early morning and when I see her around 2 or 3 she is slurring her speech, sleep talking real slow etc. thank you for your help

scott
4:25 pm August 1st, 2014

im on MMT AND HAVE BEEN TO 4 DIFFERENT clinics now. how to tell if someone is on heroin or oxy and not mmtis because teywill be “sick” about within 8 hours of doing the heroin and the methadone should last all day. you may see her tearing, spendingalot of time in the shower or bathroom (maybe showering to warm up or maybe shooting up. when an addict is high they will be very energized and talkative. it has the opposite effect on people who are not. look for needles or straws but its easy to tell ifsomeone is sick if you know what to look for. (tearing, sweating, laying round being VERY lazy, not wanting to do fun things. she may also be dressed wrong for the weather. im a Michigan boy butwhen I was sick in florida I was wearing 2 pairs of sweat pants and a hoodie in tropical florida sun because I would be so cold.

Amy
2:40 am August 3rd, 2014

I took my last 10mg methadone two days ago at 1 over 48hrs ago. I was taking 20mg a day for 5 days. Can I take xanax now or will it still be a deadly combination?

8:56 am August 4th, 2014

Hi Amy. Doctors suggest patients shouldn’t take methadone and xanax sooner than 72 hrs after one or the other was taken. While it is absolutely in the interest of harm reduction not to mix opioids and benzos, I’d say it’s better to wait, just to be safe.

vicky
4:59 pm August 11th, 2014

How long does Methadone stay in your system

1:03 pm August 12th, 2014

Hello Vicky. Although your system can rid itself of the methadone within about 72 hours, traces of it will still be detected in your urine for up to 3 weeks, and it can be detected even longer than 3 weeks on blood tests. It is a long acting medication, metabolizes slowly and recedes from the receptors sites slowly. The detection time dependends upon each individual’s metabolism, body mass, age, hydration level, physical activity, health conditions and other factors, so it’s never certain when it can be detected on a drug test.

steve
7:10 am August 25th, 2014

Hey, I took methadone for first time, I took two cap of the bottle, my eyes is diluted , how welk it take come back to normal again

priya
12:02 am August 31st, 2014

please please please can you tell me im going to take 20m then im going to cut down everyday.i want to know please when i take the 20m after how long will the 20m wear off for me to take the next mil 15m. like when you take a paracetomal you know it wears off after 8hours.
after how long does the methadone wears off PLEASE.?????.

7:27 am September 2nd, 2014

Hi Priya. For pain management the dose is 2.5 mg to 10 mg every 8 to 12 hours. For opiate withdrawal it’s recommended to take 15 to 40 mg once a day. After one or two days, a 20% daily reduction in dose can usually be tolerated. And you should be able to complete your detoxification in about 10 days.

lil' foot
2:24 pm September 6th, 2014

hello,I was on mdone for 6 mnths at 70 mgs. I started weening myself down, got 50 mgs,then had to stop cold turkey.it’s been 9 days so far, I’m still feeling very bad.cold sweats,chills,aching,headaches,can’t eat,I’ve lost 10 lbs n one week.when will I start feel in better.

lil' foot
2:24 pm September 8th, 2014

u no these clinics r good to ya as long as ur giving them money .Its been 11 days since I last went, thought I was goin to die last week,and my counselor has just now called me they suck. well I posted a few days ago what to do was in bed shape. but 11 days now and starting to feel better. on my own,good luck to everyone out there goin g through it there is light at the end of the tunnel.

2:55 pm September 10th, 2014

Hello lil’.

Most symptoms will resolve within a couple of weeks; remember that once you go cold turkey, it still takes a few days for withdrawal to start because of the long half life of methadone.

Do you have support in the form of a supervising doctor or a support group who can help you?

lil' foot
4:18 pm September 10th, 2014

yes I finally had to g poo to a Dr.
is 13 days now starting to feel better, actually ALOT better.but I can say :/ one thing, I would never wish this on my worst enemy. to those goin thorough this good luck and put it all n God’s hands he will get u through it!!!!!!!!!!!!

9:39 am September 11th, 2014

Lil’ foot, we’re glad you are finally starting to feel better. Remember, it gets better and better every day. Our body and mind are self-healing and forgiving!

lil' foot
3:50 pm September 13th, 2014

hello everyone it’s been 16 days, I feel 100 percent better. I do feel pains ALOT ny legs, but I can deal.it just feels so good to not be out there chasing something that will never b satisfying and only gets worse and worse.so I pray for all us
I was on pain meds for 15 yrs, very heavy.but can say not that I. clean and sober,that & everything else.good luck everyone!!!!!

9:12 am September 15th, 2014

Thank you for the feedback, Lil’ foot. I’m glad it’s all better.

stacjo
3:53 pm September 22nd, 2014

I shot up heroin on and off for 17 years. The most time I have been sober is 2 years and that is only because I had open heart surgery to replace 2 valves in my heart (because I ruined them by shooting up) and my heart stopped 3 times and I ended up in a coma on life support because I had an anoxic brain injury due to the lack of oxygen in my brain when my heart stopped.Even after almost dying(the doctors said it was a miracle that I didn’t) and having to learn to read, write, feed myself, brush my teeth, use the bathroom, walk, etc, I used heroin again because I still didn’t know how to cope with my depression, OCD, anxiety, and my bad childhood problems. Even with new valves, I shot up. People that don’t understand addiction would think I was crazy. I finally went to a methadone clinic, and I have been going there for 3 years now so I get a months worth of take homes. I don’t sell it because it really helps me. I never think of using heroin or crave it. It helps me with my mental health too. My problem is that it is expensive. I have medicaid, so I don’t pay as much as others, but it is still a lot for me. I am on 150 mg a day. I would like to get off of it but I know I will use heroin again because of my mental health. What can I do? Also, how long would it take to get my dose to 120?

nicole
3:04 am November 12th, 2014

I took 25 MPG of morphine liquid at 730 tonight will it last me until 830 tomarrow morning

lisa
11:47 am November 23rd, 2014

I have a few questions 1 how long do u feel the affects of methadone? 2 what do the affects feel like and how long? 3 how often do u have to dose? Is it addictive as opiates? If I’m addicted to opiates badly will I still feel the need to over take the for methadone like I did opiates and how long will I have to takenmethadone before I am cured to not use it anymore and not want it or opiates?

1:23 pm November 28th, 2014

Hi Lisa. 1) Methadone is a sedative drug that depresses the nervous system, it has a rather fast onset and the effects can last for hours. 2) More specifically, it’s slowing down body functioning and reducing physical and psychological pain, produces feelings of warmth, relaxation and detachment, and relieves anxiety. 3) If you are opioid-dependent, a single dose of methadone will keep you free of withdrawal symptoms for 24 hours. If you are taking methadone to avoid heroin use and withdrawal, it may be needed 3-4 times a day. 4) Daily treatment with methadone may continue indefinitely.

Chris
3:08 am December 2nd, 2014

Any medication that has been taken for nervous disorders, will show some side effects if used for a prolonged period.

carol
4:05 am December 11th, 2014

My son is 33 and has been going tio methadone clinic for about 2 years. He doses at about 8am in morning. He acts like his normal self when I see early in day. But at about 3-4pm, he acts totally different. He is sleepy, sluggish, slurred speech. His eyes are glassy and he appears high, is this a normal effect from methadone, or could he be taking something else, he denies being on anything else.

Deborah
4:15 pm December 30th, 2014

Hi I’ve been on methadone for 8 days 1mg 25 ml , it helps so much with my tramadol withdrawals but I can’t escape my constant dizziness. Is this normal ? Do I need a higher dose ? I would appreciate some help thank you

johnrambo269
2:42 am January 7th, 2015

I took a 5mg methadone on Sunday a 10mg on Monday n on Tuesday a 5mg….I will not be taking anymore every again!! That was the last of methadone for me…my question is am I addicted after 3days of a total of 20 mgs in all…will I go through withdrawals??? Did I screw myself…let me mention I have been on hydrocodone 50mgs for a year….I stopped taking them a day before I started taking that methadone…please I need some feed back

jarrett
2:03 pm February 6th, 2015

I went from dosing at 100 mg of methadone to 30 mg in a weeks time how sick will I get if I walk away now

Jennifer
2:14 am February 10th, 2015

Hi ,
I normally take 2 perk 10s at a time every 4 hour’s, now that I’m out of them, I got ahold of four 5mg methadone pills I took 2 & a half over a 10 hour period & haven’t had nothing for 5 hour’s, this was my 1st time taking methadone and I was wondering since I can’t tell. Is it still working? How long will it be in effect for?
Thanks

12:58 pm February 10th, 2015

Hi Jennifer. The duration of methadone’s analgesic action is usually between 6 to 8 hours. However, oral dose effects can last up to 48 hours in people like you, who haven’t been taking methadone previously.

Regina
8:18 pm February 21st, 2015

My mom was put on Mrthadone 7 years ago. After about the the first 6 months she start to become really tired, after the first year she started falling asleep through out the day. Now after 7 years she will be in the middle of talking or typing at work and she’ll fall asleep. It is getting really bad and her Dr says its normal. So my question is… Is it normal to fall asleep after taking methadone for that long?

Ashley
5:46 pm April 8th, 2015

After 2 days of taking liquid methadone, 1 mL each day, when is it safe to take a Xanax?

Cody
8:55 pm April 21st, 2015

Hey I took methadone on saterday and cold shivers have started ….I fells like I can do this but will it good worst!!! Or is it just in my head thinking about it.im going to do this but just wondering it’s a bit scarey

Cody
8:58 pm April 21st, 2015

I needs help I’m trying to get off this I took methadone saterday and I fells a bit sick and cold !!! Just wondering how long will this tak

Ashley
9:27 pm April 26th, 2015

I have been on methadone for about 7 years but getting them off the streets and I went to a clinic and they had me on 130mg. Then I got a dirty ua for a different benzo then my doctor prescribed so I got cut off cold turkey about 10 days. I’ve been able to get my hands on 20 30 mg every other day but I’m still filling bad withdrawals what do I do get back on the clinic or continue to just take a lil here n there?? How long will this take till I start feeling better or if I wing down to like a mil or 2 after will I still go thru withdrawals?? Thanks for any n all advice.

Diane
1:42 am May 6th, 2015

can a methadone addict using liquid or powder form methadone contaminate others working with
them. I am a detox tech and worry about the client contaminating ourselves and bedding etcc

Sherece
1:06 pm May 31st, 2015

I suffer from chronic back pain so my pain management Dr started me on 5 mg pills of Methadone 3 times a day. Over a 48 hr period I took 3 pills and I was so high that I couldn’t function alone. I slept for 5 days straight and only was awaken for a few minutes to either use the bathroom or to be given food. I couldn’t think or do anything on my own without the help from my husband cause I couldn’t stand on my own without falling over! I was so thirsty and drank fluids but only ate cause my husband made me eat. It took me 8 days to feel somewhat normal again but I lost 12 pounds in those few days and I was eating everyday so is this something to be concerned about considering I was 302 lbs a few days ago and now I’m 290. I have read many comments of people who take this medication for pain and want to know if feeling miserable the way I did was normal or did my body have a bad side affect to it? Does my body maybe have to adjust to this medication or could this just not be the medication for me? I need something to help the pain, but let’s me be functional at the same time. Is this what everyone goes through at first and eventually the body gets accustomed and you can be normal and still take these pills for pain? Can u please help me out and give me some guidance cause I’m new to this and my experience really scared me!

Desiree
2:15 am June 16th, 2015

If I currently take suboxone but took 50mgs of methadone once when can I take my regular dose of suboxone again?

Kaye
9:27 am July 19th, 2015

My son is a addictived to pain pills he’s quit once going thur the the sickness he started up again going thur a divorce and things been downhill. He started a methadone program 3 months ago doesnt work now the program is a hour away one way. Yells screams and says hes depressed . Is this normal? How long does it take to get off the methdone?… thank you for any help feeling helpless

billie
10:22 am July 28th, 2015

I have been on methadone for two yrs now currently worked my down from 120mg to 50mgs i havent went and dosed in now 4 days will i be getting sick because i feel fine now just low enegry

Cheristina
10:00 pm August 16th, 2015

If I have taken 12 methadone tens in the past five days what is still in my system

Frankie
2:40 am August 17th, 2015

I fell asleep at around noon today and when I woke at 7 I thought it was 7 am and took my dose 9 hours early. Will I be okay? Will this cause an overdose? I have never taken more than my usual dose before and never earlier than 3am.

10:58 am August 17th, 2015

Hello Frankie. If you have been taking the methadone for a while now, you shouldn’t experience any adverse or dangerous effects. However, just to be sure, you can call the Poison Control Center on the number 1-800-222-1222 to speak to a poison expert and get any risks assessed. They will also provide you with guidance about what safety steps you should take next, if necessary.

Cc
5:21 pm August 18th, 2015

If i have been taking 35 mg two days a eeek could i stop without going through withdrawal or how should i ween myself off. Im on liquid oral.

Jessica
6:18 pm September 29th, 2015

I took a 20 mg methadone last night. will it carry over by still working the day after. I heard it works better the second day after you take it. please let me know & also if you know any doctor that can help me in the Arkansas or Fayetteville Arkansas area please contact me @ my e-mail or on this post. need help guys… I’m out of my meds. thank

Anna
4:05 am October 7th, 2015

I am on 100mlg of methadone liquid. I have been on it for about a year straight and clean off of any other drugs. Anyway my question is if I double dose in one day will I be OK the next day not dosing?

unknown
2:14 am October 11th, 2015

I took 118mg this morning at 7am ive been on it for over two months will I be sick tommaro with out my dose

Parker33
11:35 pm November 10th, 2015

I am in PM from several back and neck surgeries. I take 100 – 150mg of oxycodone a day. I ran out of my medicine 1 week early this month. I have experienced withdrawals countless times and at that level of tolerance it’s no fun. So I procured some methadone 10mg pills just to stay well until my refill. I took 10mg every 12 hours for 7 days and did not experience any withdrawal symptoms. Now I have my meds for this next month. It has been over 36hrs since my last 10mg dose of methadone. My question is, how should I transition from the methadone back to the oxycodone? My concern is the half life of the methadone and the interaction with the oxycodone. Is it safe to take my full daily dosing of the oxy? Should I modify my dosing till the methadone is no longer a factor? If so, how?
Fyi: I am 6’3″ and 290lbs and very active.
Thanks

Sally
2:48 am November 11th, 2015

I took 2 10 milligrams of methadone 12 days ago will it still be in my system? Thank you in advance

9:14 pm November 11th, 2015

Hello Parker. Have you consulted your doctor before switching to methadone? I suggest you advising your doctor or a pharmacist before making any drug transitions.

Pete
5:31 pm November 26th, 2015

I took 50mg of Valium and 2-80mg Oxys yesterday. I took 30 mg methadone pills this morning. Will I be alright. I had no idea of half lives and all that stuff.

6:59 pm November 26th, 2015

Hello Pete. It’s best to call the Poison Control Center on 1-800-222-1222 FREE to speak to a poison expert who will advise you on what you should do next if you are in a risk of overdosing, or let some friend take you to the hospital.

desperatesara
8:58 pm December 9th, 2015

ok so i went to the methadone clinic for the first time today and really i thought it would make me feel way better so i wouldn’t be sick and stuff but i only got 25mgs today and so i asked the nurse if that would be enough to get me through the day and she flat out said NO, what the heck kinda shit is that, she said to do whatever i needed to do in order to not be sick till i came back tomorrow. now i am sitting at work and i am starting to feel like shit again and its been like almost 4 hours since my dose, can i use heroin to relief myself till i go back tomorrow

Hannah
2:03 am December 15th, 2015

Can you take methadone after using heroin without withdrawal symptoms occurring? I’ve heard using suboxone too soon after using heroin can put you into a worse withdrawal and I wanna make sure I wait long enough after using heroin before my first dose of methadone. I start a methadone program at 7 am and would like some answers or advice before then!!

Dexter
9:19 pm January 7th, 2016

I have been on methadone now for 14 years, and am on a dose of 80mg in a solution (orangeTang) if i miss my dose for some reason, i will be experiencing hot flashes and cold sweats by noon only 28 hours after taking my previous days dose. I have been telling my doctor about it but he doesn’t help with any information on why i am feeling like i am in withdrawal. I also sweat profusely and have to carry at least one or two extra shirts if i go out anywhere. The sweating is very annoying and stops me from doing lots of activities where physical activities are concerned. I would like to know if maybe i am somehow able to process and eliminate enough drug to actually start to experience the symptoms of withdrawal. I always feel pressured by my doc to lower my dose and i don’t because how crappy i feel by noon if i don’t take it early enough the next day. Thank you

Kenneth
5:29 pm January 9th, 2016

Im planing to get on methadone for pain management, I am scared that after a while that I would build up a tolerate and it wouldn’t take away my pain how long do think it would be before that would happen…or do you think it would possibly not happen,,, thank you Kenneth

Sata
6:32 am January 10th, 2016

How come my methadone doesn’t last more than 8-10 hours I take it how I’m supposed to and I don’t want to go up on my dose which is 95mg orally? It seems like I feel the irritability and withdrawal feeling by late afternoon??

Linda
8:09 pm January 13th, 2016

I’m taken 85 mg of methadone if I go sleep will it work same has if I stay awake .

mike
9:07 pm January 14th, 2016

I have taken methadone recreationally for close to a year. I almost always wait at least 5 to 7 days (or longer sometimes) between doses (oral 60~80mg). I am a normally hyper person and the buzz is gone within 6 ~ 8 hours. I am a bit sleepy the following day, but feel normal after that. over the holidays I, for a week or 3, I took some more within 72 ~ 96 hours. What sort of Jones can expect.

Amy
5:06 pm February 1st, 2016

I started off on 20mgs of methadone , now up to 75mgs..
.my question IS…. Why does 20mg and 75mgs seem to be the equal amount of liquid? I’m self pay at my clinic and want to make sure I’m getting my full dose and not being cheated

John
7:39 pm February 6th, 2016

I’ve been on the Methadone for almost 2 yes.. and running,,anyhow ,,every time o get up and go dose myself at this convenient little Methadone Clinic I smoke a cigarette and usually drink coffee a lil after that I dose,,point being after its all said and done I go to the restroom to release whatever I ate that morning, pointblank I go this the rest room and take care of bitnezz ,so how does that work???!!!,like if I were to Digest would my methadone dosage come OUT with it as well or how does that WERKK???!!!???!!!!!!???!!!

Stephanie
12:54 am February 7th, 2016

I am on 15 mg of methadone if I walk off of that how bad will the withdrawal be

Starla
7:29 am February 7th, 2016

Can you take methadone 10 hours after taking a buprenorphine

Lydia @ Addiction Blog
8:34 pm February 8th, 2016

Hi, Starla. I suggest you consult with your pharmacist.

Lydia @ Addiction Blog
5:54 pm February 10th, 2016

Hi, Stephanie. Withdrawal symptoms vary from person to person, and they mostly depend on the frequency of use, dosage, metabolism, diet, etc. I’ve read that experts reported that gradually reducing the drug is a safer way to quit it. So, I suggest you speak with your doctor or a pharmacist to help you create an individualized tapering schedule.

Alana
2:12 am March 9th, 2016

My partner has been on 30ml of methadone for nearly three weeks now. Hes been put on methadone after being addicted to painkillers for 13 years. A couple hours after hes had his methadone, he just sleeps. He cant stake awake for anything and thats him asleep for the night until next morning when he goes to chemist to get his next dose. So everyday hes in a deep sleep from around 2-3pm till the next morning. Is this normal? Im worried!

Brittany
12:11 am March 17th, 2016

I have been on methadone for five years now at the Macloud Center. I am on 90 mg now. I have been on 90 for at least six months now. I was feeling fine for until about a few weeks ago. I start having withdrawal around five P.M an I ushally dose around five A.M. I don’t understand why I am feeling like this all of the sudden. I know 90 is a pretty high dose so I just don’t get it. I am also scared to tell my counsellor I might need to move up again. I don’t want them to think I am just trying to get high or something. I am not. I can’t deal with this though. Have I built a tolerance to this or something? Will I have to always keep moving up! Please give me a answer. HELP!

Matt
1:53 pm March 18th, 2016

Hi, I’m currently on M.M.T. I’ve bee going for about 3 months and wanted to keep my target dose low because I’ve been through this before and coming off is the WORST!! I’m wondering why I’m having to keep going up. I was on up to 200mg morphine iv daily btw before I started the clinic, but is it possible to find a stable dose or will I just keep building a tolerance to the methadone and keep having to go up? also I’m preparing for when I do have to quit the clinic like stock piling morphine for when I first come off and subutext when I run out of the morphine. any advice would be greatly appreciated! Thank you.
MATT

Charity
1:18 pm April 6th, 2016

I have been on Methadone for several years now. Started off with pill form when I was on pain management, now I’m on 60mg liquid form that I get from methadone clinic. My concern is my body aches so bad. I can’t use my hands most of the day because the pain and aches i feel in them. Half the time in dropping stuff because of it. In waking up all night long because the way my body feels. In having severe joint pains. My bones feel sore. I hurt all over. Yes, it does take the back pain away for a bit but pain comes back full force within 5-6 hours, but feels worse than because all the joint pain. In having more than just body pain, I hardly ever have bowel movements and my teeth are so brittle. Some have broke and some had to be pulled. I seen 2 different dentist who both have said its from the methadone use. I was never told about any of these side effects and it really has me passed. I feel like in in my 60s because I can’t move around as well as I should be able to. In only 40. I was told this drug leaves your body within a few days. After 2 weeks I was in tears. My body hurt so bad that I was forced to go back to the clinic to start dosing again. I have noticed that in forgetting things, my memory isn’t very good either anymore and my head just feels fuzzy sometimes. I can’t help to feel that the methadone is playing a part in this as well. Im really scared about the effects this is causing but Im more scared about the pain I will feel without it. Im struggling on what to do. Had anyone else been going through this, if so is there anything that you of that helps with all the pain your feeling? I just think I should have been told about all this before I was put on this drug in the 1st place. Im on the verge of hiring an attorney because people should be informed so the can make a better decision before putting this drug in their body. I think doctors and clinics know this but the money is great and tests why they keep giving it out. I pay $400 a month for this poison. Im paying for my pain and that’s so sad to me. Please if anyone is dealing with this let me know what you do for rrelief.Thanks so much in advance for any suggestions.

Charlene
8:05 am April 20th, 2016

My question is that I heard from a friend awhile back that in either to feel the methadone u gotta take it for a few days for it to build a tolerance in order to feel the methadone? is that true cause I got some from a friend to see if i wanna get prescribed to it cuz i was unsure if id like it or not … if i take one or two im i gonna feel the pill?

Lyndsay
11:04 pm April 27th, 2016

I have been on a methadone matenence program for about 6 yrs now and have noticed that I will sometimes go through withdrawal symptoms a week before my menstral flow. Is there a reason for this?

Sue
5:58 pm May 31st, 2016

I’ve been in excruciating pain lower back from an industry job, a 300+ pound patient collapsed on me in mid transfer in 06. Put on Vic’s till they didn’t work then norco now perc’s which are starting to not work. Then 1/2015 a car pulled in front of me my low spine has bulging disks one now is pinching the nerve which is quite painful. Will the methadone give me more pain control than the perc’s which at times I’ve taken two. I know that can’t be good for my liver. The doctors are not ready to do surgery but my day to day is ridiculous pain levels ranging from 6-10+. I can’t even stand to do the dishes. And info you can give would be Great! Thanx

Cody
3:18 am June 2nd, 2016

I take them together but I’m wanting to know if the valium is taking away from my dose because it doesn’t seem to last as long as it use to before I had to start on the valium which is only 2 of the 5mg a day.Please.Need good info.Thanks to whoever can help me with this question.Take 100mg and doesn’t seem to last over 12 HRS.

Robert
7:21 pm June 4th, 2016

I
I take 5 ,10mg of methadone for the last 5 months how do I detox without getting sick

Adam
8:15 am June 8th, 2016

I’m on a private clinic. Been taking liquid, 70mgs a day for over 6 years. The last 8 months I only take 70mgs a day, for 2 or 3 days. Then I will skip 4 days before taking my next dose. Is it possible that I have lowered my tolerance to where I can get off methadone easier than if I dosed daily? I wanted to know if my tolerance is low enough to where if I stopped, will I still have withdrawal.

valerie
4:10 am June 19th, 2016

I am starting Methadone treatment in 3 days. They start new comers on 30 mg day 1, and increase 10 mg everyday until you feel its enough. The first day I think I might go in with one bag of Dope in my system just so I don’t get sick. Im asking will I be sick if i don’t dose a little heroin before going into methadone tratment. I hate heroin and want to get off but I don
t want to be sick. I don’t use heroin heavily. I use about 5-6 bags a day for 4 years on and off. I used a week at a time the most in those for years. . Do you think I will still be sick the first day? Im scared to feath but I want help so bad. Thank You!

Tarek
3:18 am June 22nd, 2016

I just went through a rough night I cold turkey quit methadone,well yesterday I took my normal 140mg dose of methadone at 7am & then 12hrs later got my prescription of Suboxone & took half a strip at 7 P mi went into withdrawal for 8brutal hrs& & that was yesterday & today no dose & by the way I’ve been on methadone for a year & a hLf & 140mg& hadn’t been back since yesterday to METHADONE clinic;& not GH going back but it’s been 36hrs since last dose& took a 2mg strip of Suboxone and main ? Is will I be safe if I take Suboxone after 96hrs if for a year & half I was daily taking 140mg of methadone

Tarek
3:20 am June 22nd, 2016

I daily take 140mg of methadone & now switch to Suboxone & will I be ok if I take Suboxone after 96 hrs of cold turkey QUITTING METHADONE

Jennifer
6:18 am June 22nd, 2016

How long on 70mg orally now for going on 4 years will it take to get away from it all together . ?with that uch will you ever have any sex drive again male 34 years old .?and lastly does it increase anger in a different way almost like jealous to let your girl have fun because you only want to lay on the bed and watch tv after pm daily on days off all day long . And angry if his girl is out enjoy herself with children and friends ?what should you do for it . Does he need couples counseling or call a 7 year relationship quites? Hopefully you’ll be helpful with your answers . I’m his girl and 45 don’t need to waste my time if he’ll never be up for anything anymore . . Comes from a family of using drugs . Now he thinks he’s perfect and we’re all looser to even have a beer and fire .

Lydia @ Addiction Blog
5:24 pm June 23rd, 2016

Hi Tarek. I suggest you consult with your doctor about this.

ij
1:55 pm June 25th, 2016

I go to the methadone clinic and I am on a hundred and thirty milligrams of methadone is it dangerous to be that high

Jason
9:28 pm June 28th, 2016

I was taking 115mg of liquid methadone at a clinic. I missed 3 days and they kicked me out with no help, I need to know how long the withdrawals last, or how long I will be sick? I do not want a relapse.

Lisa
3:48 pm July 13th, 2016

How long does one does 10mg of methadone stay in ur system

Jackie
4:23 pm July 15th, 2016

I’ve been on 110 mg of methadone for 2 years. I wanted off bc of all the negative side effects. I came to my parents out of state where I have no medical insurance, to detox at home, & switch to suboxone. I’m aware of how dangerous && idiotic this is just pls bare with me. What’s done is done now. The problem is I took my last dose on July 9th, which was 6 days ago & Have yet to feel any serious withdrawl. I am so confused. And discusted is this crap really hanging on to my receptors for dear life?? I’m tempted to throw myself into precipitated withdrawl just to be done with this mess. I have a 7 year old son who my mom is looking after for me & It’s just getting old at this point I expected to be down for a week but not to be waiting and anticipating. Every Dr office I call cannot advise me bc I am not their patient. And I’ve been doing research for days and haven’t come across any story like mine. Please help!

Nick
7:38 pm July 16th, 2016

Hi I have a question I’ve been taking methadone for 5 days at 30 milligrams a day pink liquid I had a moderate pill addiction 4 or 5 green perk 15s for about 9 10 months I haven’t had no pills in 7 days 5 of them was because of methadone I don’t want to take the methadone anymore should I just stop cold turkey what would happen how long would the effects last will I have any of that I don’t know I just know that I don’t want to get addicted to methadone

Lydia @ Addiction Blog
12:53 pm July 19th, 2016

Hi Lisa. Methadone can be detected in urine 2-4 days after the last use.

Bob
9:54 pm July 20th, 2016

I just wanted to tell anyone that’s reading this that you just have to suck it up! Deal with it no matter what! I’ve been a junky on and off since I was 23! I would be clean for 5 years here a couple there and pretty much quit cold Turkey my last stretch was for 12 years and then I hurt my back and started taking pain killers and that progressed to slamming dope again. So someone gave me the brilliant idea of getting on Methedone. Big f****ing mistake! I was on 130 mg a day for a couple years and started dropping over a year ago! I got down to 7mg and stopped 2 weeks ago! I tired of being sick everyday. My problem with stopping anything is the Emo shit and not sleeping! I can’t give you a rundown of how many days this happened but, I can tell you it’s getting a little easier! Just don’t give up! If you’re a young person, You don’t want to be in your 50’s like me going through this stuff! This is my cure! Going through the hell that I brought on myself! This is just the beginning! Force yourself to walk and eat, read, Internet occupy your time! I lost everything this time! My wife kid everything I cared about! I know I will never touch another opiate again! I have a half a bottle of pills left and I’m not even tempted! I hate this crap! Good luck! It’s worth it to just stop!

Charity
8:31 pm July 21st, 2016

Keith.. It takes your body a week or so to get use to the dose that you been raised. I was the same way. I even was throwing up from it. Just make sure you eat something with fat it it 1st or very very shortly afterwards. Your body absorbs meds much better when you eat fat calories 1st. I use to be on 80 mg for a year then I quit going after my mother passed away and went back to street drugs for 2 months. I went back to the clinic over a year ago and I am stable on 60 mg it last all day into the next day and I’m not having withdraws or any side effects. Matter a fact I’m on phase 4 and I take my full week of meds home with me. I only go to the clinic in Tuesday’s. Every time I want to go down in dose my body feels it and I do start wanting other stuff meaning street drugs. I don’t know why. I have been on this crap for 4 years. I started taking it in pill form 1st now on the liquid. I do know when you go off this crap it takes a long time for it to leave your body it stays in your bones forever and your body hurts, seriously hurts. It hurts worse than withdraws. I’ve dealt with both and getting off of methadone is so much worse. So keep that in mind before you get to fat in methadone treatment. I see 2 other doctors and they both told me that liquid methadone is a synthetic heroin. My aunt was a heroin user for 13 years and she said the methadone was so much worse getting off of as well. Even thoe I’m still on methadone I still wanted to give you the heads up. Plus if you like your teeth you might wanna stop this crap now. It years your teeth and body up. Good luck.

Mathew
3:52 pm July 26th, 2016

Im on 90mg methadone. I also have liver problems. When I take my drink, 24 hours later I start sweating. And only a few hours after that I start to have muscle contractions. That’s when it starts to hurt. Withdrawals I mean. My girlfriend thinks its all in my head but its not and Im tired of fighting over this. Its not her pain. Can you explain this in an email so I can show it to her and end this debate. Im not imagining pain. Thank you please. It would be a big help.

Lydia @ Addiction Blog
6:03 pm July 26th, 2016

Hi Nick. I suggest you consult with your doctor to help you plan an individualized tapering schedule. Experts claim that slowly lowering the drug dose is a safer way to quit it. Also, speak with a pharmacist to recommend some over-the-counter aid that can help you ease withdrawal symptoms.

Barbara
11:39 am July 27th, 2016

I’ve been on methadone about 10 years three of the years not getting you from the doctor just taking a few here and there off and on for 3 years but now I’m in a pain management and I’ve been on it for 7 years I found it pretty good 40 milligrams a day sometimes I do an extra dose in the afternoon but that’s rare now I decided I want to get off of I’ve got 80 pills to start to wean off I know how to wean off by cutting back on doses every week take us lower dose each time but don’t do it too quick what I mean by that is don’t come back too much but enough for you feel ok I’ve had 16 surgeries in my lifetime so there was 40 and 64 and I’ve been experiencing severe pains in my leg and back from the medication I read on the internet that it causes spinal stenosis after doing a survey of 279 patients that took methadone and the other 279 to compose email and their findings were that it causes spinal stenosis I believe that because of the severe pain that I have and I don’t take it I don’t have that pain so I just want to know how long will it take after I wean off to feel normal will I have enough pills to get me through the winner process I hope so I just don’t want to go into any withdrawals I’ve been there and it’s not fun at all it’s like living in hell which I know nothing about but that’s the only thing I can say LOL

Tins
8:10 pm August 10th, 2016

This medication was prescibed to me.
They are 10mg of the Methodone.
I took one dose @ 10:30 last night.
I want this feeling to go away.
How long does it take to start exiting my system.
Im sick

nicole
8:40 pm August 14th, 2016

Can u use methadone to subcide heron withdraws for 3-4 days without becoming dependant, even after being on a methadone maintanance in the past?

Mary
1:32 am August 18th, 2016

How long will the symptoms of 100 mg. of methadone for 3 years last? the person has been clean for 30 days and still horrible symptoms. if one symptom goes away another just replaces it, no relief. Combined heroine and methadone duration was 6 years. 29 year old female about 125 lbs.

Vall
4:45 pm August 19th, 2016

I’ve been taking methadone for 2 yrs how long does it take to get out of my system

gtity
4:16 pm August 20th, 2016

Too the person coming off xanax…be careful..u can have a seizure..wean off…slowly ..little less each day…for about 10 days

Kevin
10:23 pm August 28th, 2016

It has been 96 hours since my last dose at 25mgs of methadone I have been on it for three weeks . I have had cold chills and can’t sleep . Am I almost threw this or is there more withdraw to come.

Gwenn
4:22 am September 1st, 2016

My son has been in recovery and going to a clinic a in Michigan for about 8 months. Today, he fell off a ladder and fractured his hips and pelvis. He also broke his wrist. He will be having surgery in a couple of days for his wrist and then to a rehab center for his his and pelvis. As you can imagine he is in a great deal of pain. He said the pain medication they gave him in the hospital have no affect because of the methadone. Can you tell me how long it will take for the methadone to wear off. His dose is 95 which I thinks is great because he started at nearly 160. Will he have to be weaned off pain medication

Charity
9:42 am September 2nd, 2016

Hi Gwenn,

I went through a injury as well and my dose amount was 80. That stuff stays in your body for awhile. Don’t let them peploe from the clinic tell you differently. I went and seen a specialist about Methadone. It takes up to 6 months for it to come completely out of your body. It stays dormant in your bones. It also breaks down your bones and teeth makes them very weak. Easily to break. The clinic people don’t tell you that either. They don’t inform people very well of all the side effects. It can range from getting sick all the way to sexually issues. Some are pretty bad. Now for him to start feeling his pain medication, he will need to stop taking the Methadone and he should get a little relief in about a week. Even though he cant feel the pain medication working it really is. The reason it doesn’t work well is b/c that crap is running through his body. I was on it years ago then I got off of it for over 6 months I still couldn’t feel the pain medication. You never really get that feeling back at least I never did and I know a few other who has been off for over a year and they are going through it as well.. Methadone is the best pain medication. They use it as pain medication. You don’t feel the high as you do from pain killers it just relives all your pain. I like it that way.. I don’t like the high, I just cant bear the pain.. My spine is so twisted so there isn’t any pain killer that helps me, that’s why I decided along with my doctor to just get me back on a steady does of the methadone. It was the best decision for me when it came to my back. So your son might want to try that for his pain. It’s worth a try. I do hope he gets well soon and finds some kind of relief. God bless him…

Joseph
5:48 pm September 13th, 2016

how long it needs to feel heroin high after 11 months of methadone Use (40Mg) per day ?

David
7:16 pm September 15th, 2016

Hi I was on methadone for maybe 2.5-3 yrs. left at 47mg (couldn’t afford it) cold turkey. Sick for a long time but was unemployed at the time. Stayed clean for a while until an extremely tragic family event. So I started using heavy again, then about 3 yrs. ago I went back to the clinic. I just finished at 2mg last Thursday and am super excited to have this ball and chain off my ankle, and the cost and time blah blah. I know the last time I left it was just short of hell for quite a while. I would love an estimate on when I’ll feel good without shivering and feeling incredibly off. I was at 180mg then dropped an dropped till about 60-50 maybe then went down about 1mg/ day. Thank you so much for any help or info.

Cody
9:37 pm September 18th, 2016

If You take 100mg of Methadone a Day but then get thrown into a situation to were You only have 120mg to last You 4 Days until Your next dose how should You divide that 120mg for those 4 Days with it taking the less effect on Your body?Is is best for you to just divide it and take 30mg a day or maybe skip the next day

Sarah
10:49 am September 21st, 2016

Someone I know accidently took two 10mg methadone thinking they were Midol. What can I give her or do for her to help her get through this &/or speed the process along so she’s no longer sick?

Lydia @ Addiction Blog
3:24 pm September 22nd, 2016

Hi Sarah. Call the Poison Control Center at 1-800-222-1222 for an assessment of overdose risk or with help on what to do next.

Casey
10:08 pm October 6th, 2016

Hi ive currently been on suboxyn for the past 6 months about 2 mg a day last week on sun i got a 40 mg methadone wafer and divided it up into half quarters and took that daily so like 5mgs a day i ran out today which is thurs so 5 days of 5mg methadone can i take 2 mgs of suboxyn in the morning? itll be right at 24 hrs simce taking methadone?

Cmain
10:20 am October 9th, 2016

I took 22 mlgs of methadone 8am Saturday am. I am switching to suboxone now how long do i wait?

Michael
6:23 pm October 17th, 2016

yo thank you this really helped.told me everything not just some little parts

leo
3:05 pm October 19th, 2016

Hello
I just started the methadone clinic about 3 weeks ago. I am currently on 55mgs. i was wondering why is it the dose seems to wear off a bit towards the early evening hrs like around 4/5 o’clock”. I was on Suboxone for a about three years before this clinic, and when i was on the Suboxone it seemed to not wear off like this, but I also would spread my medicine all throughout the day, 16mgs to be exact. I take the 55mg dose every morning at around 6AM. Thank you for your time!!

Crystal
6:05 am October 21st, 2016

I take methadone daily the oral liquid! I was on 128 and at that dose since had a baby. I went down after baby and have been on that dose for about 6 weeks. I just went down day before yesterday from 128 to 100. I didn’t feel it until today. I’m not sure if sick cuz of something ate of cuz of the drop? My plan is to try and get off it but unsure how to get off best and what to drop n how often?? Can you give me advice? My insurance is ending on Oct 31 so that’s my reason. Thanks in advance for your help and advice!!

Kelli
12:03 am October 25th, 2016

I’m on 140mgs of methadone on MMT….I have high metabolism they told me…(not that this applys to my question really)but I’m trying to get OFF of methadone and switch to suboxone after being on methadone for 6yrs!! So I was wondering how long it would take my body to FULLY WITHDRAW 140MGS OF METHADONE!? I know,was told, and it states methadone takes 2-4days after last dose. Now I just got another “answer” today to my question also, which was absolutely totally different from what I read before, and knew?! I have not relapsed in 4 years on July 5th 2016, I DO NOT want to fall down or go down that path ever again! PLEASE HELP, IM TRYING to do this the right way to switch to suboxone, not the “wrong way” :( Thank You for your help & support

Chris
5:16 pm October 27th, 2016

I have been attending the methadon clinic everyday for 35 days now but have to go out of town for the next two days and the clinic I attend was not able to set me up at another clinic while I’m out of town for the next two days.How bad or if any does anyone know if I will have bad ,severe or even moderate withdrawal symptoms by the the time I am able to dose three days from now. I am currently in 95 ml daily oral solution.

Brandon
6:13 am November 2nd, 2016

I am on 80mg and want to get off. But the clinic is making me jump through so many hoops just to decrease it 5 mg every month what are some more options?

Lydia @ Addiction Blog
7:24 pm November 4th, 2016

Hi Brandon. The usual methadone tapering schedule:
– Decrease dose by 20-50 percent per day until you reach 30 mg/day
– Then decrease by 5 mg/day every three to five days to 10 mg/day
– Then decrease by 2.5 mg/day every three to five days

Joanne
5:09 pm November 7th, 2016

Tooh 20 mg yesterday after having none for 4 mo. How long before it’s out of my urine.

J
3:42 am November 16th, 2016

I took 45mg and about 10mg every hour the total was 100mg is that safe? I usually take 60 everyday tho. I felt a lot better doin it this way just wanna know if it’s safe

Lydia @ Addiction Blog
3:03 pm November 17th, 2016

Hi J. I suggest that you speak with your doctor about your concerns.

New patient
2:33 am November 26th, 2016

I took my first dose of prescribed methadone today it was 20 mg, been feeling ok not craving pain killers but I am afraid that later on tonight I will begin with the WD can some one tell me if that is good till the next dose which is tomorrow morning like around10:30 am

Anthony
1:48 am November 27th, 2016

After injecting methadone how long can it be detected in a mobile drug unit

Kevin
4:57 am December 1st, 2016

I took my regular dose of methadone at 7 this morning. I fell asleep early and thought it was 8 in the morning and took my other dose. Come to find out it was only 13 hours later not 24. Will I be okay? I have tooken more than my usual dose many times but just hoping I’ll be okay.

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