Tuesday October 21st 2014

How long does morphine stay in your system?

Morphine is absorbed and metabolized quickly by the body.

For most standard drug tests, like the DOT 5 panel drug screen, morphine will only be detectable for a couple of days after taking the medication. However, morphine is detectable in hair for longer periods of time. More here on drug screens for morphine and where to go if you have a morphine problem. Plus, we invite your questions about morphine in your system at the end.

Main morphine uses

Morphine is used as a pain reliever in cases of moderate to severe pain. Morphine belongs to the opiate class of medications and alters the brain and nervous system’s response to pain, causing numbing effects which are actually based on the way that we PERCEIVE pain. Morphine can also cause euphoria, which is one of the main reasons people abuse morphine and take it for non-medical reasons.

How do you take morphine?

Morphine comes in the form of an immediate-release tablet, an extended-release tablet, and an oral solution (liquid). When swallowed and taken as prescribed, morphine provides effective pain relief. However, morphine abusers will sometimes chew or crush the tablets to release all the medication at once. They may also crush the tablets and either snort them, or dissolve them in water and inject the mixture into the blood. These modes of administration are not recommended as chewing, snorting, or injecting morphine raises the risk of overdose and dependence.

Peak levels and half life of morphine

Morphine starts to take effect quickly. It reaches peak levels within 60 minutes when taken orally – within 30 minutes of injection. The drug has a half-life of about 3 hours in a normal oral formulation. It may take longer to clear the system depending on how it was administered and the health of the person taking the morphine.

Morphine drug testing: How long does morphine stay in the body?

Narcotic pain medications like morphine don’t stay in the body very long. When drug screening for morphine, blood tests are the least used method due to the short detection window, followed by urine and hair tests. Note here that all types of morphine drug tests are reasonably accurate and reliable. And that a positive drug morphine screen indicates use.

How long does morphine stay in blood?

Due to its short half-life, morphine doesn’t stay in the blood long-term. It will typically fall beneath detectable levels after a day.

How long does morphine stay in hair?

This kind of testing may be used to monitor someone’s compliance in a drug treatment program, as morphine is a known drug of abuse. Most drugs can be detected in hair for about 90 days. This does depend on how long someone’s hair is, how frequently they have haircuts, and how much of a drug they’ve taken. Additionally, trace amounts of morphine will be harder to detect. Although hair sample testing for morphine is not standard for employment and most other contexts, hair samples can detect morphine abuse triggered when you take morphine to get high.

How long does morphine stay in urine?

The exact amount of time (the morphine detection window) depends on the amount of morphine a person is taking, what formulation of the drug they’re using, how long they’re used it, and other factors. Typically, morphine can be detected in urine for 1-2 days. In cases of heavy or chronic use, morphine might be detectable for slightly longer, but it usually can’t be detected after about 4-5 days.

Morphine and addiction

Morphine is a highly addictive drug. Even when taken as directed by a doctor, morphine can be habit-forming. The drug can give a euphoric high when taken in large doses, which opens it up to abuse. With morphine addiction come the risks of withdrawal and potential overdose.

Morphine in your system questions

We invite your additional questions about morphine in the system below. We try to respond to all legitimate morphine questions with a personal and prompt reply. And if we don’t know the answer to your question, we will refer you to someone who does.

Reference Sources: DMME: Drug Free Workplace
Medline Plus: Morphine Oral
Toxnet: Morphine

PubChem: Morphine

Leave a Reply

47 Responses to “How long does morphine stay in your system?
Jane Tilly
2:58 am September 20th, 2012

If you had morphine for pain, and now want to do weed, what are the chances of getting hooked on weed?

9:09 am September 22nd, 2012

Hello Jane. Thanks for your question. Addiction is characterised by psychological dependence on a psychoactive substance. If you take morphine or weed and get high, you have the chances of becoming addicted to either. If taken for pain and taken as prescribed, you may become physically dependent on morphine or week….and/or tolerant of their effects…but addiction is much less likely. Where on you on the use for pleasure factor?

heather schwartz
2:45 pm December 31st, 2012

ive been taking morphine er 60 mgs twice a day for almost two years i found out i was pregnant and the doctor suggested staying on the morphoine but comming off very slowly so there are no withdrawal symptoms to me or the baby so it wouldnt cause premature labor.. we are decreasing five mg each week but my due date is fastly arriving what is the largest dose to desrease by to not have these withdrawals

Ali
6:21 pm February 3rd, 2013

My mum recently died of cancer She was in severe pain and i Was Giving her 10ml morphine oral solution Every hour when required . Three times the day she passed away At the back of my mind I think that I might of overdosed and killed her I asked the doctor and he said no. But would like a second opinion Just to put my mind at rest

10:52 am February 12th, 2013

Hello Ali. I am sorry to hear of your loss. I am sure that you are looking for answers to your questions about why your mother has passed. If your mother was taking morphine for some time, she would have developed a tolerance to it, meaning that her body could process higher amounts or morphine or more frequent dosing. The morphine probably helped her manage the pain, and is not likely to have caused her death.

Bob Bard
6:41 pm March 19th, 2013

How long after morphine is injected into a vein will it be detected in a urine sample ? The fact pattern with which I am dealing is Morphine was administered at 1:45 A.M. and a urine sample at 1:48 A.M. showed the presence of unspecified opiates–is is reasonable to think that the urinalysis finding represents the shot of Morphine or is it possible that some opiate drug taken earlier might be the cause ?

Bob Bard
12:01 pm April 2nd, 2013

How long would it take a patient’s urine to reflect the presence of morphine ? I’m a lawyer defending a personal injury lawsuit and the injured plaintiff was administered an injection of Morphine at 1:45 and a urinalysis done from urine taken at 1:48 showed the presence of opiates–is it possible that the opiates present in the urinalysis were from some form of opiate taken earlier in the day or does Morphine show up in the urine that quickly (…i.e., 3 minutes…) ?

Thanks.

2:19 pm April 3rd, 2013

Hello Bob. I’d suggest that you take this question to a professional toxologist or Medical Review Officer who works with a private laboratory that administers drug testing. You’ll need an expert opinion on this matter!

Bob Bard
3:19 pm April 3rd, 2013

Actually, I did have the matter reviewed by a nurse expert with a background in pharmacology–her opinion was that it would probably take up to two hours to appear in the urine but when I contacted a doctor with a background ni pharmacology she said the Morphine would show up instantaneously. Faced with two conflicting opinions, I thought I’d see if you could provide a “…tie breaker…”, so to speak.

7:00 am April 4th, 2013

I see. Try a search on your internet browser using these keywords:

site:.gov morphine metabolism

There are quite a few published reports on the issue. But as far as opinion goes, ours is unqualified, as we are not medical professionals. Maybe you can call Quest Diagnostics or a similar lab and ask for testimony from the supervising medical doctor who reports drug screens as either positive or negative.

Bob Bard
5:41 pm April 4th, 2013

…just wanted to say “THANKS” for your prompt, to the point help. I’ve tagged your site as a “FAVORITE” for the future. Be well.

Della Taraborrelli
9:41 pm April 11th, 2013

If a patient was on morphine (prescribed by a doctor for three years) for chronic back pain, how long does it take for the morphine to be completely out of their system? Also, does morphine leave you with any permanent side effects. Does it do damage to short term memory? Is there any other side effects that you are left with?

Judy
5:58 pm April 21st, 2013

Hi I have been taking morphine for 14 years now for central pain syndrome after 8 strokes I am trying to get into a pain clinic to refill my script in NM but until I do I will start withdraws and would like to know what to do until I get seen
Any help would be helpful
Thanks j pearce

Rica
5:48 pm June 3rd, 2013

I recently had to take a urine drug test for my dr at the pain clinic I go to and he told me I tested positive for morphine. I have not taken morphine whatsoever since probably almost 2 years ago when I was in the hospital. How is this possible that I tested positive for morphine when I have not taken any? I do not want my dr to discontinue my pain medicine for something I didn’t do. I do take Percocet and flexaril for my pain and those are both prescribed to me. Please help! Any info at all would be greatly appreciated!

John
11:21 pm September 23rd, 2013

If a person took 58 Morphine Pills. How would they appear from the OD?

Virginia
6:01 am September 27th, 2013

Should a person be on oral morphine if she is in recovery from drug addiction?

10:09 am September 27th, 2013

Hello Virginia,

This question is really one about personal management and needs in addiction recovery. Some former opiate addicts benefit from long term use of methadone, while for others it can become a crutch and get in the way of recovery. Doctors recommend at least 6 months of opiate substitution before considering weaning off…and most recommend longer terms. But when methadone maintenance becomes a lifestyle and is not accompanied with psychotherapy, support groups, or personal growth…I think that it can encumber recovery rather than enhance it.

cyndee gross
2:27 pm October 10th, 2013

I take ms contin 100
and morphine instant release
20 years now
yet only a trace showed up in my blood test
why?

Jenna
7:39 pm November 5th, 2013

If clean and take 100 mg time released morphine how many days max to get it out of urin

jbug
10:24 pm February 2nd, 2014

My step daughter’s mother passed away but wasn’t found till 3 days later ,they said it was a high dose of morphine in the system ,would that had been even higher at the time of death ? I was just wondering because the mother was reaching out to people and calling them on the night she would of passed away to people she had not reached out to in years ,so in the back of our minds we all have wondered if it was a suicide but being it was almost 5 days later after she passing that they did the toxicology ,could if had be missed ???

Marcus Maxwell
10:34 pm March 24th, 2014

I take 15mgs of morphine 3 times a day as needed for my back. Took a drug test it tested negative, everything else I take showed up but the morphine. Mind you awhile back I had a drug test prior to this one, and numerous ones before this latest one now im negative and no longer can be seen at this clinic. P.S . I’ve even had Percocet show up in my urine and i don’t take perc’s!

Boonchob
3:11 am April 10th, 2014

I interesting in drug discovery in men for confrimation.

Katie
6:03 pm May 4th, 2014

On Friday I was in the ER because they though I had a kidney stone. I was given morphine in my IV 4 times. I am still filling off, and sluggish. I was wondering how long it will take for it to be out of my system, for me to feel better. Thank you Katie

Jay
3:19 am May 28th, 2014

Hi there, My question is I’m prescribed morphine as a every day pain reliever from my doctor and have an active prescription. I’m starting a new job where I have to take a drug screen can my employer deny me employment based off a positive opiate test with an active prescription?

8:55 am May 28th, 2014

Hello Jay. I’m not sure about the legality of such a decision on your state. Check with you state attorney general’s office for details.

Cheryl
1:24 am June 14th, 2014

My boyfriend was in the hospital for kidney stones and they gavw him 4 mg of morphine. That was 5/6 days ago and he hasnt felt very well since then amd has maybe taken a handfull of pain meds in his 32 years bc he doesn’t like to take stiff like that. If he isnt used to opiates could he be experiencing afyer effects still?

Denise
8:56 pm June 17th, 2014

I have been on Morphine ER 100mg 3x a day with 4mg hydromorphon for break through. I have severe chronic pain due to failed back surgeries, I by no means have ever abused it. I have been taking this over ten years, over the past year with diet and exercise feel that this drug is starting cause more pain, and I just don’t want to take this anymore. So for the past few months I have managed to get myself down 100 mg a day which would be 50mg since they 12hr acting, is this true? but now I have struggled with this last one dose. As of 6 days ago I completely stopped 100mg and 180 hydromorphon, and I need to know will I stop having theses withdraws soon? Also what can I take that is not a drug to help my body through this. Thank you

Jewels
7:50 am June 27th, 2014

Hello, I was wondering if you could help I am on a high dose of morphine due to kidney trouble I take 350 mg twice a day. I have been on these tablets for years and now I have a bad ulcer which has left me in a lot of pain I am even dreaming in pain and this has made me use more of my morphine, I thought I could cut down and make it up but I was unable to do this. Can my doctor say no to me and leave me with nothing on this high dose. Thank you I look for to your answer I have to see him this afternoon

Ivana @ Addiction Blog
9:09 am June 27th, 2014

Jewels, thank you for submitting your comment! You are clearly in a lot of pain. Let us know what your doctor says!

emma
5:54 pm July 2nd, 2014

Hi
I’ve been on 20mg sevredol tablets 4 times a day plus buprenorphine 70mcg/hr for 12 years. Does anyone no how long it will take to come out of my system after I’ve stopped taking them? I have weaned myself off the tablets and now trying to wean myself off the patches.
Many thanks
emma x

Ivana @ Addiction Blog
8:37 am July 3rd, 2014

Hi emma. The withdrawal symptoms of morphine-like meds, such a s sevredol often last 1-2 weeks. Since you were taking the medication for so many years, quitting abruptly can be dangerous and there is a possibility for occurrence of the standard opiate withdrawal syndrome. After detoxification, some effects may last even after months pass.

Buprenorphine withdrawal after long-term use can also be a challenge. And the symptoms are often compare with those from heroin withdrawal. The withdrawal effects from buprenorphine usually peak the first 2-5 days, but you still may experience mild symptoms for several weeks.

How long will they stay in your system depends upon your metabolism, weight, physical activity, age, level of hydration, general health condition and other factors.

Jo
5:27 pm July 12th, 2014

I have been taking ms contin 30 / twice a day for a couple years for chronic pain. Also take hydrocodone 10/325 4 x day. I am getting divorced and my husband is accusing me of abusing drugs. I was ordered to take a drug hair test. The results were negative. How can that be right? Is it because the dose is low and my body metabolizes quickly? I am not abusing it – take it as prescribed. Can you give me an answer? My attorney wants me to get my doctor to explain and I want to make sure he has the right information for the letter. I am running out of money for attorney fees and co pays! thanks!

Tracy
1:52 pm July 19th, 2014

Hello I desperately need you to help me. If I have taken about 70 15 mg pills of morphine over a period of 10 days how long does it stay in your system and can a blood test tell how much is in your system? Please help. Thank you

dandyelle
2:13 pm July 23rd, 2014

HI I am hoping for some advice. Am currently withdrawing from buprenorphine and am wondering if taking morphine sulphate will help with the symptoms?

1:42 pm July 24th, 2014

Hello dandyelle. Morphine is not an appropriate treatment for buprenorphine withdrawal; seek help from your prescribing doctor for tips on tapering, setting up a slow withdrawal calendar, and managing symptoms of withdrawal.

Socialuser2
8:59 pm July 29th, 2014

My friend did 20 units of morphine injected but missed his vein how long will I take to get out of his system it was a small amount and wasn’t injected right he also took 2 small hits of crack how long will it stay in the system and how can he flush it out for a drug test they may be sent to a lab

Sharon
4:19 pm July 31st, 2014

I’ve been on morphine for years. I was up to 45mg 3 times a day at the peak. I am now down to 1/2 of 15 mg once a day, and have been there for three months. Every time I tr’y not to take that 1/2 pill I go to withdrawals. and can’t stand all my nerves jumping, so I take it. Is there anything to counteract this.
Also is coming off morphine causing my hair to fall out or is it the occipital nerve block series I just had?

Mike Tisdale
12:15 am August 19th, 2014

I took 360mg. Of Morphine Friday night and 10g of Morphine 6 am Saturday morning. With the half-life indicated on this page, in your opinion, do you think it will be our of my urine by Wed at noon.?

Mike
3:49 pm August 19th, 2014

I took 360mg of morphine on Friday night and 120mg on Saturday morning. I have a UA on Wednesday at noon. In your professional opinion, will I pass? I am doing alot of sweating and drinking water, please answer soon!?!

mike
2:53 am September 5th, 2014

I passed, thanks for the timely reply

Jennifer
8:23 am September 6th, 2014

My husband was recently hospitalized with a severe case of diverticulitis. During his 7 days in the hospital he was given 3 to 6 mg of morphine every 3 to 4 hours in his iv. Now that he’s home he is getting chills then sweating and agitation off and on. I think he could be going through withdrawal. Please tell me if you agree. He has only been home for a day and a half. If this is withdrawal, how long could it last? Thank you.

ohn
1:13 am September 23rd, 2014

I had a drug test for a job n I sed a freinds sons urine he is 8 they dont do drugs maybe a joint once in a while I smoke too thats y I used his urine.ne way it tested positive for morphine he haant takin ne medicine wat so eva maybe chewable tylenol so y wud he test pos forphine? Does kids bodies naturally make it maybe idk im a gear head thnx in advanced I cant find any info on it

Tiffany
7:08 pm September 23rd, 2014

My pain med doc switched me to ms contin 30mg 2x’s a day because of an insurance issue. The first month went great but now I am seeing what could be some crazy side effects. Is it possible that side effects take 30 days to show up for the first time, or should I be going to my regular doc to figure out if something unrelated is happening? Thanks!

Ivana @ Addiction Blog
1:53 pm September 25th, 2014

Hi Tiffany. It’s best to go and see a doctor. Your doc can check your symptoms and determine what’s causing them, before making a diagnosis.

ann
2:00 am October 4th, 2014

Should the doctor do cheak up on you every 3month or so
ike blood test, blood pressure,

been on morphine for 6years.thank you for your help in this matter.ann.

Mandi
4:35 am October 7th, 2014

Hi,
I had an operation on my foot 12 days ago, they gave me morphine, for what I have no idea as I was in NO pain what so ever!! I am still getting dizzy spells, I cant sleep but Im tired all the time. My head is sooooo itchy. I dont have nits as I have got my husband to look a dozen times!
Is this normal??

Mark
4:34 am October 11th, 2014

I have been on morphine 30mg x2 @ day for many years. I take it along with a lot of other medicines daily. About six months ago, I had severe chills and shaking and went to the emergency room. They said I had a urinary tract infection and treated it with antibiotics. I was encouraged to drink plenty of water. About a month and a half ago, I again had severe chills and was shaking and again went to the emergency room and was iv-ed powerful antibiotics. I was told I had double pneumonia and sepsis (a blood infection). After a short hospitalization, I came home and appeared fine. I monitor my O2 levels daily. After the first hospitalization, I starting drinking lots of water to avoid future infections. After the second hospitalization, I added Gatorade and more juices. I have PTSD and one of my main symptoms is hypervigilance-which means when the doctor says do something I do it obsessively whether drinking more water or taking medicines. I have never missed my morphine medication. I was called in for a drug test and no morphine showed up. Also two other drugs, baclofen and clonozapam (?) did not show up. Could drinking large amounts of water (about 16 glasses a day) cause my urinalysis to be negative for morphine? I have never missed taking my morphine or the other drugs. If so, should a pain management specialist be aware of this?

Thank you.

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