Thursday January 18th 2018

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Tramadol dangers

Tramadol use can be fatal.

However, Tramadol is more likely to cause severe side effects, such as seizure. We review how and why Tramadol can be dangerous for you here.

Dangers of Tramadol ingredients

Tramadol, also marketed under the brand name Ultram, is used to relieve moderate and moderately severe pain. Tramadol belongs to a class of medications known as “opiate agonists,” although Tramadol also causes inhibition of the re-uptake of norepinephrine and serotonin.  Does Tramadol have codeine in it?  No.  But like any opiate medication, Tramadol affects the central nervous system and can cause drowsiness or difficulty breathing.

Tramadol can also be dangerous in people with seizure disorders or a history of brain or spinal infection. Because of its addictive potential, Tramadol is not recommended for anyone with a history of alcoholism or drug addiction.  How long for Tramadol to work?  Onset of action when taken orally as prescribed is usually under an hour, however intravenous injection brings almost immediate onset of pain relief.

Additionally, Tramadol is also dangerous in combinations with a variety of other drugs. Tramadol interacts with several different types of medications, including, but not limited to:

  • antifungals
  • antidepressants
  • herbal supplements, especially St. John’s Wort
  • MAOIs
  • other pain medications
  • sedatives
  • SSRIs
  • tranquilizers

FDA warnings about Tramadol

The FDA advises doctors never to prescribe Tramadol to anyone with suicidal thoughts or tendencies, as the medication can sometimes exacerbate these conditions. Tramadol should also be avoided by people who suffer from depression or mood disorders. Heavy drinkers and drug users should never take Tramadol due to the risk of serious side effects or death.

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Serious adverse side effects of Tramadol

Even at normal doses, Tramadol can cause serious, potentially-deadly side effects. Anyone taking tramadol should consult a doctor immediately if they experience any of the following symptoms:

  • difficulty swallowing or breathing
  • flu-like symptoms
  • hallucinations
  • hives
  • hoarseness
  • rash
  • swelling in any part of the body

Signs of Tramadol overdose

There are a few distinct signs of Tramadol overdose to look out for. They include:

  • decrease in pupil size
  • difficulty breathing
  • extreme drowsiness
  • seizures
  • unconsciousness

An overdose may result in coma, heart attack, or death, so it’s important to get medical help right away if you suspect an tramadol overdose.

Help for tramadol use or misuse

Tramadol is often abused and creates both a physical dependence and tolerance in habitual users. Drugs like Tramadol can create a compulsive “need” for the drug in users, and cause unpleasant withdrawal symptoms which make it hard to quit using.  Withdrawal symptoms of tramadol can occur even after a few days of prescribed use!

The good news is that there is help for people physically dependent or mentally addicted to Tramadol. A local doctor or clinic should be able to direct you to resources and help you deal with your addiction. They may use a medical or therapeutic approach, or a combination of the two. Or you can look for local support groups, like Narcotics Anonymous.

If you have any more questions about the risk or danger of taking Tramadol, please leave your questions here. We try to respond to all legitimate questions with personal and prompt replies.

Reference Sources:  American Society of Health System Pharmacists information on Tramadol
Tramadol Overdose as a cause of serotonin syndrome 
FDA: Important Drug Warning for Ultram 

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18 Responses to “Tramadol dangers
Gary Pagac
6:00 pm February 12th, 2012

Since having rny gastric bypass surgery 1.5 years ago, i cannot EVER have any nsaids for pain. I can have tylenol and Tramadol _only_ . No injected nsaids either. Tramadol is a life saver for an occasional injury i get while mending a fence, kayaking, etc. Making it a narcotic? It would be a great disservice to a large and growing number of people.

larry woodruff
11:13 pm February 4th, 2013

i think tramodol acts just like oxycodone

3:31 am October 20th, 2014

Someone close to me was addicted to heroin and tamadol and crack cocaine she overdose by using tamadol and heroin and now is in a coma. I don’t recommend anyone doing this. God Bless.

7:10 am December 8th, 2014

Hey Ummm y question to you is what are the risks in carrying a baby n taking tramadol I take 300mg a day I’m 6 months pregnant .I’m trying to taper myself off of them as much as possible can u please help me out on this I really would love to quit cold Turkey but I know that the withdrawal will be hell for me as well as my baby. I really hope you can give me some insightful information on this
Thank-you in advance

11:57 am December 12th, 2014

Hello Samantha. Tramadol has been shown to cross the placental barrier, and it’s advised not to be used during pregnancy unless it’s absolutely inevitable. Animal studies have revealed evidence of embryotoxicity and fetotoxicity, but there are no controlled data in human pregnancy. I’d suggest talking to a doctor and a gynecologist to review all the options available. Congratulations on soon being a mom!

7:15 pm December 26th, 2014

I have a Tramadol addicted woman. Could Tramadol change the manner of woman against her husband, i mean does it encourage her to search for another man to make love? Does Tramadol addiction help in that?

3:14 pm January 12th, 2015

Hi Ashraf. Tramadol addiction can lead to lowered libido and loss of interest in intimacy. However, increased libido is reported only by a few people who take Tramadol. More female patients were experiencing increase in sexual drive, and they were 40-49 years of age. Still, this effect was only reported by 0,01% of people who were taking Tramadol.

2:18 am January 26th, 2015

Hi I’m 16 years old almost 17, I’m just after having knee surgery and will have another one in 6 weeks I dislocated my knee cracked 2 small pieces of bone off , reptured my acl , torn my LCL and have a minscal tear I’m in severe pain all the time so prescribed tramadol since mid December, injuru happened 9 the Dec. My question is I’m really young and feel like I’m relying on tramdol a lot im always counting down the hours until I can take more.. I’ve been sleeping a lot more and I feel like a ‘junkie’ when I try to not take them and take over the counter meds instead I start to sweat and get dissy, I’m really afraid that I’m addicted to them but they are the only pain relief that’s working for me. So if I went to my doctor and said it to him will I be on a less pain relief that won’t work? I’ve to take 6 33mg a day. I was first on 50mg once at night but niw its 33mg of tramadol and paracetamol in the one tablet – 2 3 times a day.
Any advice?

5:12 pm March 13th, 2015

My son, an Army Iraq veteran, died of an overdose of Tramadol. Coroner ruled suicide. VA disputes this and denies any fault. Medical records clearly indicate: do not prescribe narcotics, suicidal. My question: Isn’t this medication known for causing suicidal thoughts/ideation? They claim they were in their medical rights to prescribe it to a patient with a history of drug/alcohol use. I pointed out and clearly outlined their mistakes in the medical records. Other VA hospitals did not prescribe it for the reasons mentioned above. They claim they took him off suicide watch but records indicate otherwise. Any comments on this drug would be appreciated. No accountability. No one cares. 22 Vets commit suicide every day.

Paul Riddker.
4:49 am June 24th, 2015

New Zealand Medsafe “failed” to add the FDA Tramadol suicide risk.
My life, and my whole family have had our lives destroyed by negligence, Tramadol is a dangerous drug.
The New Zealand government has trued to conceal my story.
Read more here:,
Search key words: Paul Riddler, Human Rights Complaints New Zealand.

10:59 pm January 3rd, 2016

Well, I have Suffered from Chrinic pain for Many years! I initially used Over the Counter Meds, as my Pain intensified I finally went to a local Pain Management Specialist!! The Medications Really did help at first, but as time progressed it became a Prison I was Shackeld to!! Now I have taken the steps to Wean myself off Opiates and have a New start in life! That sounds Great however my Wife of over 24 Years is Ditching me when I need her the Most! The Moral of the Story is keep your priorities in tact because my Life pretty much Sucks now and I am 46 and know nothing other than my Wife and Family life that is going down the Crapper of Life!!! I don’t even have Drugs to Ease the Pain! I am Feeling it at Full Force!!! Heed my Warning so you Do Not end up a 46 year old Heartbroken person that is Only Happy when I am Asleep and Cannot Feel!!! Dean

5:48 pm March 20th, 2017

Can Tramadol be used to get of alcohol after you haven’t drank in a week

Lydia @ Addiction Blog
9:33 pm March 20th, 2017

Hi Richard. Please use Tramadol only as prescribed by a doctor. It seem that alcohol is out from your system, since you haven’t drank in a week.

8:18 pm April 5th, 2017

I have been taking this drug for over twenty years for spinal problems, but in the last four years have suffered epileptic episodes including tremors memory loss etc. I also had a heart attack and whilst having after treatment the doctor discovered I had been having heart arrhythmia for at least ten years. I have tried to find an alternative, and have reduced the amount I take, but now have a lot more pain. I live in Mexico, where not all medicines are available.
Many thanks


Lydia @ Addiction Blog
1:37 pm April 14th, 2017

Hi Michael. I suggest that you look for a pain clinic that will take over your case.

2:03 am July 26th, 2017

I would like to know about any interactions tramadol might have with klonapin, ambien, sertraline, briviact, vimpat locosimide. These are some of the meds a family member has been prescribed. I need a definite answer so I can ask my drs to adjust these meds, for safety reasons. Seems these days the patient is responsible for keeping track of what these white coats are doing! And it’s a damn shame! it’s like going to medical school or a short class every time we go to the dr or have a hospital stay. And all the research that is done when your loved one is sick– is usually done by you, not a dr or a medical team- why?! Then what are we paying so much for?! Really?! Sure seems like we do a lot of the work, and if THEY agree then they sign paperwork, oh and read images. But, give me a minute and I could too!! So, yes please, some clarification would be nice. Thank you

10:16 pm September 24th, 2017

I was taking tramal 50mg since a long due to pain in leg muscles : I did not know it is hazardous : I am trying to get rid of it ; but how should I do

Lydia @ Addiction Blog
12:56 pm September 26th, 2017

Hi Hassan. I suggest that you consult with your doctor to help you create an individualized tapering schedule.

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