Can you overdose (OD) on tramadol?

While it is possible to overdose on tramadol, you can experience severe health complications at lower doses if you don’t take tramadol as directed. More on how much tramadol is safe for you and tramadol overdose here.

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Yes. You can overdose on tramadol.

Although the amount of a drug it’s necessary to take to overdose varies greatly, most drug overdoses are unintentional. And a tramadol overdose can be avoided. What can you do to protect yourself from an accidental tramadol overdose? And what happens when you take too much tramadol? We explore more here, along with the risk factors for tramadol overdose. Your questions about tramadol addictive drug and overdose are welcomed at the end.

Can you overdose on tramadol?

Yes. You can overdose on tramadol. However, how much tramadol to overdose will vary from person to person, depending on previous exposure to narcotic pain medications.  Plus, if you are mixing tramadol and alcohol, your risk of overdose increases.  But even without overdosing on tramadol, it’s possible to suffer severe health complications when you take too much tramadol.

What happens when you overdose on tramadol?

The most dangerous complication of tramadol overdose is slowed or shallow breathing. Tramadol overdose can cause your breathing to stop completely. Other medications combined with the tramadol may also cause overdose, or make these effects more pronounced.

Keep in mind that if you are taking tramadol to get high, tramadol abuse increases your risk of death and overdose. This medication should only be taken swallowed as a whole pill, and only in the doses recommended by your doctor. You’re much more likely to overdose when you chew, crush, snort or inject tramadol pills.

How many tramadol is too much?

The amount of tramadol you need to take to overdose depends on your previous exposure to opioids. You can take more tramadol safely if your body is already tolerant to tramadol, opiates, or opioids. The safe doses for tramadol will vary between different strengths and formulas of tramadol. For example, if tramadol is mixed with other medications, such as acetaminophen, it can be much easier to overdose on the combined product. And if you’ve developed a tolerance to tramadol, you’ll have to have your dosage increased under a doctor’s direction – and you should never start taking more without your doctor’s input to avoid the risk of accidental overdose.

It would be difficult for an adult to take enough tramadol to be fatal. However, it’s very easy to exceed the maximum safe dose of 450 mg tramadol a day. And at doses around 500 mg many people begin to experience seizures and serotonin syndrome. Furthermore, a tramadol OD is a little more difficult with stronger medications – fatalities have been reported at doses between 2.65 and 8.2 g, which is 5-18 times the recommended maximum daily dosage.

Because of these risks, you only should take the amount of tramadol prescribed to you by your doctor. Never take more than recommended by a medical professional, and only take this oral medication as directed.

Tramadol overdose help

If you’ve taken a high dose of tramadol and experience adverse side effects, the outlook is good. Prognosis and recovery without long term damage is possible if breathing has not been compromised. Realistically, you’ll probably recover because it’s so hard to OD on tramadol.

In a more serious case of tramadol overdose, your doctor may administer oxygen to help you breath better. This is because although uncommon, tramadol overdose can be deadly. The lack of oxygen reaching your brain due to depressed breathing can cause permanent brain damage. Luckily it’s hard to accidentally take this much tramadol.

Overdose on tramadol questions

If you have any questions about safe amounts of tramadol in your system, please leave them here. We are happy to try to help answer your questions about tramadol, and will try to respond with a personal and prompt reply for all legitimate queries.

Reference Sources: Toxnet: Tramadol
Medline Plus: Tramadol
FDA MedWatch: Tramadol hydrochloride tablets
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. My Son is an opiate addict but he has been clean since he left recovery 2 months ago.
    Night before last I found out he stole 22 of my Tramadol (I use for severe arthritis) with out my knowing.
    He went into a horrible Seizure, I thought he was dying on me…when EMS got here he had just got up from the 6 min’ Seizure and refused to go to the Doctor/Hospital.
    Now he is hurting in his legs etc…I am sure because of the rigorous state during the Seizure. It was a nightmare for this old-Mom.
    Could he have passed away?

  2. I’ve been prescribed tramadol for several years now and this morning I was taking my meds and accidentally took 4 50mg pills should I be worried or do I need to go to the doctor what do I need to do I normally take 4 50mg pills a day through out the day

  3. my sister took 20 tramadol as a overdose which was 1000mg . we found out she stiff it through her nose. but she sadly pass away …why

  4. Hi I’ve had serious pain in my stomach after an operation. I’ve taken 2 50mg of tramadol in one go. My breathing has slown down a lot and I feel very hot. I’m starting to panic what can I do?

  5. A couple of years ago me and my mates went out and we ended up buying NRG-1 so we went back to my mates house and we found his grandpas tramadols, so we started mixing them in with the NRG and I took 17 tramadols not sure what mg they were but after an hour or 2 had went by I woke up in a hospital bed from an overdose! Worst experience of my life, I couldn’t lift my head up without being sick and to be honest I wouldn’t wish it on my worst enemy’s! So the story here is don’t mix your uppers with your downers?

  6. I am addicted to heroin so i have a really high tolerence to opioids and i just took 13 50 mg tramedols bc i herd they were opioid based pills. The other day i took 7 and it didnt do anything. So what im asking is do they get you high or am i just waisting my time trying and am i pushing it by taking so many?

  7. I have abused tramadol for quite sometime now and i take 12x 200mg tablets in the afternoon washed down with half a dozen beers everytime and i havent overdosed yet, well i think ive come close to overdosing i just want to know is it normal to be taking 2400mg of tramadol in one sitting

  8. I took 2 tramadol yesterday within a 10 hour window and I was very sick- it took my migraine away but also made me have other symptoms. I was throwing up, very light-headed, very nauseous, weak, accelerated heart beat, and more. I am in day 2 of this situation and are feeling even worse. I now have my migraine back; but also very feverish, accessive sweating, accelerated heart beat, weakness, light headed ness and more. What is wrong with me and how do I flush this out of my system?

  9. I have no prior history of seizures and have taken Tramadol in the past along side my Zoloft and suffered no serious health issues. Nonetheless, I’m very cautious about how I take these.

  10. I have taken 50 mg of tramadol three times a day. My prescription said 50mg to 100 mg three times a day. I increased to 100 mh three times a day. I suffered side effects of sweating and constipation. Can I safely cut back to 50 mg three times a day ? Not realizing that there are side effects what do you recommend as a alternative to tramadol ? I have a Dr’s appointment april 25th 2018 he may have some suggestions.

  11. I have a nephew I have been taking care of for a while who is 16 , I took him to the dentist due to a broken tooth that went to the nerve and hurts intensely, the dentist prescribed him 50 mg tablets of tramadol, he woke up from sleep from the pain and took 3 which would be about 150 mg, will 150 mg in under an hour harm him?

  12. I accidentally took 2 pills –50 mg each–within an hour of each other. I took one on 2/17 at 11:30 p.m. and another on 2/18 at 12:39 a.m. The other times I took pills on 2/17 were 12:00 am, 9:45 am, 5:00 pm. Am I in danger of an overdose? Or other serious effect? Thanks.

    1. Hi Deborah. Call the Poison Control Center at 1-800-222-1222 for an assessment of overdose risk or with help on what to do next.

  13. I have a friend in her 70’s who takes 6 Tramadol a day. 2 every 6 hours. She uses 30 every 5 days. Isn’t this too much. She also takes Tylenol 3 in between times and constantly applies Voltaren to her knees many times a day. I’m concerned for her health. Is this dangerous?

  14. Hi, i have a prescription for tramadol 50 mg. however, i do not like taking that much at night. i was thinking of trying just a half or a quarter of a pill. is that safe or would it dissolve to quick and be possibly fatal i am 55 and weigh 180 lbs


  15. I am on alot of medication for epilepsy and ms I am on steroids aswell and having the dose reduce every 2 weeks because I am having alot of side effects I am taking tramadol regular during the day for pain …tonight I took 600mg within half an hour not realising i had already taken them. I am not feeling great now double vision headache shaky will I be ok …thanks for your help Angela xx

  16. My brother in law just said over the phone he took 10,000mg of Tramadol tonight but also took Klonopin to “break the seizure threshold.” His speech is slurred and he is repeating himself. Is it even possible to take that much Tramadol or is he just out of it?? He has abused benzos,alcohol, etc for a long time

  17. I was taking 7-8 100mg tabs a day for back and neck injuries for about 4 months, im not sure what study has been done for this site to say that 450-500 mg is to much. Im here telling you that after the first week of taking the prescribed dosage more could be needed. Tramadol after taking for a short time builds tolerance very quickly, i was told to start at 4 100mg tabs a day, thats 400mg a day plus 500mg af Tylenol along with it, and i my tolerance grew fast thats why 7 100mg a day was taken and im fine no problems whatsoever. Like i said i would love to know what kind of study was done cause i really think your numbers are false.

  18. I take 500 mg tramadol 3 times a day. I have never had any problems with seizures etc…and i only take that many after being solely on them for 6 years. If i take less than that by mid night i am sick. SICK SICK. Is it possible to be ok taking that much for so long–and then that same amount causing breathing problems?… i hate tramadol. I tried getting off them but even suboxone doesnt allow me to function w- being sick.

  19. i lost track on when my last does were,so i accidentally took 43(50mg tramadol) in 24 hours. breathing isnt a problem, but vomitting and back pain are.

    1. Hi Gallen. Call the Poison Control Center at 1-800-222-1222 for an assessment of overdose risk or with help on what to do next.

  20. Hi i take 2x 50mg tramadol 4 times a day my back has gone into spasum and ive been laid up fo 5 days in agony can i take more tramadol or what else can i do

  21. I am totally addicted to tramadol.I have been taking tramadol 100 2ml(5 injection) every day. First, I started taking these just for pain relief with just one or two. Gradually, I increased the amount and started taking these for recreational purpose.I have to take 5-6 injection everyday or I dont feel good. I really need to get rid of it. It isnt possible overnignt. I hate doctors and its not possible for me to go to rehab. What process can I follow to get rid of it without facing any major withdrawal symptoms?

  22. I just took 500 mg of tramadol at once will I be okay anf what could the effects be im 5’6ft and weigh 110lbs

  23. Hey there. I was taking my dogs tramadol recreationaly and i took 400mg over the course of an hour or hour and a half. Will i be ok? I have not taken this before

  24. Last night i took 2 tramadol pills (can’t remember the dosage) to get a high of some sort…I felt fine then I started feeling weak and shaky and my heart rate + breathing was faster…this morning I’m still shaky and I feel fine when I lay down but when I get up I feel sick/vomit, what should I do and am I gonna be okay without going to a hospital?

  25. Hi. I took 6 50mg tramadol so 300mg for pain and I just now started on the medication and I’m scared of ODing. Am I in the clear or do I need to call emergency services?

    1. Hi Nicole. Call the Poison Control Center at 1-800-222-1222 for an assessment of overdose risk or with help on what to do next.

  26. Last night I consumed 2,000 mg of Tramadol with no alcohol just before going to bed for the night.
    I had difficulty falling asleep although my mood was cheerful.
    All day, the next day, I was sleepy and almost dozed off a few times. As a pain killer it is much to mild for any realistic effect. I am Italian American with a serious spine disease and am 77 years old.

  27. I have been taking tramadol 100 2ml(5 injection) every day. First, I started taking these just for pain relief with just one or two. Gradually, I increased the amount and stateted taking these for recreational purpose. I am totally addicted to it now. I have to take 5-6 injection everyday or I dont feel good. I really need to get rid of it. It isnt possible overnignt. I hate doctors and its not possible for me to go to rehab. What process can I follow to get rid of it without facing any major withdrawal symptoms?

  28. I just crushed 2 tramacet and had an ounce of gin , I also take 100mg of topomax before bed … I had 1 crushed tramacet earlier today about 6 hours ago … and 1 beer … first time I have done this …

  29. I take 50mg of tramadol and now it does not seem to work. Can I take 100mg at a time and be safe? I only take as needed

    1. Hi Larry. I’m guessing you are on the generic immediate release tramadol of 50 mg. Will you be ok to take 100 mg at once depends on how long you’ve been taking the medication and your tolerance levels.

      People who haven’t taken tramadol before will start out with a low, immediate-release dose. They’ll be prescribed 50 mg tablets to be taken every 4-6 hours for pain – but they may be instructed to only take half the dose, starting at 25 mg for the first few days, so that they don’t take more than 100 mg in one day.

      In patients who’ve experienced more exposure to the drug, safe doses may be as high as 450 mg a day. However, this is a determination that needs to be made by the prescribing doctor. So, you should not be taking more tramadol than prescribed on your own.

  30. I took one Tramadol Acetaminophen 37.5-325 and then another a few hours later. Will this put me into overdose? It’s recommended dosage is 1 every 4-8 hours I believe. I’ve never taken this before and I want to make sure I’ll be okay. Idk if my weight will account for anything but I’m 220 lbs.

  31. I received Tramadol 50 mg, recommended dosage 1-2 tabs every 4-6 hours. I took 2 for pain. Reactions were migraine, vomiting, hot flashes and I felt like I was gonna pass out. Im also allergic to codeine. Is it safe for me to take these meds?

  32. Hi yesterday I drank 8 cans of cider then while I was really drunk I took 3 x 50mg of tramadol. It was a silly drunken mistake. I have barely bn awake all day. I am an Alcoholic and have needed a few drinks. I haven’t got drunk, mainly as I can’t stay awake. I have only bn drinking mixer cans of vodka n cranberry juice. Low ish alcohol level. Whats is worrying me is I took the tablets over 24 hours ago and im still really sleepy n groggy. I am not used to strong pain relief. If something bad was gonna happen would it have happend already ? Will i be ok ?

  33. So i have a tonsillectomy 24 days ago. I had a few bleeds 2 weeks ago and 1 week ago which set me back and i found that I didn’t need the tramadol the 1st 2 weeks but I do now.

    I was taking 2 50mg per day then upped it to 4 yesterday. Today I’ve been sleeping odd and I took 1 at 12noon another 2 at 6pm. Another at 9pm and another at 12:40am. So that’s 5x50mg or 250mg in the last 12 hours. Which now seeing 450mg over 24hours… This scares me. Is this okay? I’m about to go to sleep again and I probably won’t take another until 10am-1pmish. I’ve only been taking them for 2 weeksish and increased it more today to suit the pain. I’m trying to take 12hours off it so I don’t “overdoese” Will i be okay?

  34. I’ve been taking tramadol for around 4 months, about 3-4 pills ( 225 mg each) a day. today
    1st question is about what happened today> II felt dizziness few time,but I’m not sure if its because tramadol (I usually take around 7pm 1 pill then around 9 1 pill , and after midnight I take 2 pills) or because the weather was cold and was not wearing so much clothes. and 2nd question, is about how I can stop taking without going to a rehab,I tried to decrease the dose alone but I didn’t..
    Every day I say tomorrow I will decrease, and then I do nothing and just take the normal dose
    . 4 years ago I took tramal for 1 year and 2 months and it was around 200 mg everyday and I guess its because this my tolerence is not normal or something. I really need help. Thank you

  35. I think I was Rx too strong a dose of Tramadex OD 300. It’s a 24 hour release. Previously I was taking the Tramadex drops, 40 drops equaling 100ml. Each dose relieved pain for 4-6 hours.
    Now I have the 24 hour release Tramadex OD 300 and that seems to me to be triple my dose? Is this because it’s time release?
    Or did my Dr make a mistake and Rx too strong. And if so can I cut the pill in half or thirds?
    Btw, I’m in a foreign country and don’t understand the dr completely nor does she understand me so I can’t ask her and have confidence in comprehending the answer.

  36. My friend took four tramadol at all at once last night after she drank almost half a bottle of wine. After that her breathing slow down a lot so I gave her a Monster to speed up her heart rate and some vitamins. It is now morning and this happened last night. She claims that she is dizzy and her breathing is still kind of slow but it’s a lot better. I just want to make sure if she was going to die it would’ve been in her sleep last night? Should I still be concerned that she could still die? She didn’t do this to kill her self she did it to get high like a dumbass I was drunk on wine when she did

  37. I was in a lot of pain in the course of four hours I took 6 Tramadol. I don’t have a breathing problem I am tired so I am drowsy but it is also late. But my pulse is running fast is that a side effect of the medication? I do not usually take that much I usually take 3 a day but I was in such pain I was not thinking.Please let me know if that is too much Tramadol.

  38. My fiance took 16 tramadol pills (not sure of the g/mg) w/ in 5hrs. His breathing and speech is NOT normal. I made him drink lots of water, but what else should I do ?

  39. I have recently been put on tramadol. 50 mg. My directions sat to take one to two tablets every 8 hours as needed. I took some this morning around 8 a.m. then again at 5 p.m. before I went to work. And then at 8:30 p.m. when I got off. I know it’s not exactly what the directions told me to do. I just want to make sure I’ll be okay, I’m one to always fallow the directions. Any advice or help needed. Thank you

  40. I prolapsed a disc and have recently had surgery, within the last 2 weeks, along with diclafemac,
    for some reason one day I had more pain than usual due to a physiotherapy session, I am on 100mg tablets and the prescribed amount is 1 twice a day, for some reason I took 2 100mg tablets every 6hrs unintentionally, I have just realized but I think I have taken 600mg in the last 24hrs , I weigh 15,6 stone am I at risk?… not going to take any more, I took the last dose at 5.30 and I am going to try and push through the pain barrier for 24 hours an the resume the correct dose, I made the mistake because I was originally taking tramadol with gabapentin, diazepam diclafemac and tramadol, the gabapentin prescription say to increase the dosage.
    I have now had a successful back surgery so I am no longer as much pain just very sore from the physiotherapy and the which is why I took the wrong dose, as you can appreciate the combination of the other medication does cause confusion..I am drinking lots of fluids and have just had a large dinner to try and slow things down. Should I take any further steps?
    any advice would be appreciated.

  41. I accidentally took 500mg of Tramodol, instead of 50mg because the other meds I was taking(for pain) had made me confused. I think this is probably a risk that is not being fully addressed.

  42. Good day. I have been taking Tramadol twice per day for almost 1 year now. I am taking close to 200 mg per day for chronic pain from a pancreas/Digestive issue.
    My question and concern is: 1) Is taking this amount for a year or so , dangerous or considered too long? My doctor said he’s had patients on it for several years with no harmful effects, but I am still concerned , due to all the bad news on opioids.
    2) I usually use a splitter to split my pills due to swallowing difficulties. Is splitting these 50mg pills dangerous to my health, too?
    Thank you and hope to hear back from you very soon.


  43. Hi…. I need you help… i took 7 100g of tramadol last night and i woke up this morning feeling dizzy and couldn’t pee up to this moment … pls what am i to do?

  44. A 15 year old girl takes 7 50mg tablets all at once, could this be serious? Would medical attention be needed? She has previously taken 2 50mg tablets and has violently thrown up several times in the next 24 hours.

  45. Not sure if i need to get help or ride it thru. In the last 10 hrs ive popped 26 50mg tramadol, 3 duromine,my usual 225mg of efexor. My bp is 180/110. Ive cleaned my whole house but even resting Im sweating. I havnt slept n feel quite heady loose. I hav broken fingers but being a recovering addict,the take the whole lot been clean for 8 mnths ..cant feel my fingers tho,so thats gud

  46. Hi I’ve been taking 30mg codeine x2tabs when needed for arthritis but they weren’t effective when I had a flair up so Dr prescribed tramadol.
    I took 2x 50mg then 5.5hrs later another 2 pain went felt OK. Next morning I was hot cold shaking dizzy and throwing up with a massive headache this stayed with me for 2days and took 4 days to feel OK. Why was this? I haven’t taken any since and have gone back to codiene

  47. Hi , a person took 100mg 20 tablets tramadol and passed out for 24 hours and when woke up had no memory dont know their relatives or anything like a new person.. And the person is 65 years old . Is this permament or there is way to help to get memory back ? Thanks.

  48. My brother passed away on the25th of Aug.. On the 24th we took him to the hospital. They gave him,Tylenol 1000,morphine and another pain killer sent him home with a prescription of 30 tramidol. I found him dead the next morning. 2 -3 days later I found the bottle there was 10 missing.The corannor walked into his room maybe for 5 mins. And said it looks like he had a heart attack. Do you think that is possible? ?

    1. Hi Linda. I’m really sorry for your loss… May your heart and soul find peace and comfort. I’d suggest that you speak with a toxicologist or a coroner or another medical professional about your concerns. We’re not able to provide you with a qualified response.

  49. Hi, I m eating tramadol 12 capsules per day since 5yrs now i am addicted to it and i am unable to decrease the dose, please advice me what should i do and also i eat lorazepam of 2mg*3

  50. 10 x 50 mgs tramadol, 60mg Prozac with alcohol 6 days ago. Had jerking and twitching all night. Brain still fuzzy and am uncoordinated. Still jerking during night. Hoping that may stop. Not sure if this is seton in toxicity. Also feeling hot flustered and out of sorts. Any ideas?

    1. Hi Deb. Have you called your doctor? If not, I suggest you to consult him/her ASAP. And, please consider that it is illegal to consume medications other than prescribed because you put yourself at risk.

  51. I took 10 of 50 mgs tabs with alcohol the other night. I felt an incredible sense of calm until I went to bed. Then the muscles twitches started all night long. That was Friday and now it is Monday night and I am still twitching at times. My head remains spaced out. I didn’t want to go to hospital as I am in that profession. Never again

  52. Hi. I’m having laser hair removal, so I took 2 Ultacet (37.5mg) for the pain 4 hours before treatment. The first time it worked great, but in the next session I didn’t feel any pain relief, so I took 3 capsules the next time without food. It made me very sick, with nausea, vomitted 3 times that day, drowsiness, and feeling overall bad )on the positive side, it did reduce the pain during laser treatment)
    Question: why did the 2 capsules didn’t work the second time, and why did 3 gave me a mild overdose?

  53. I have 150ml tramadol I got them of someone I get 30mg cocodamol of the doctors but don’t get them till tomorrow I took the last cocodamol at 7.30 am will the tramadol be safe to use

  54. I took my daughter to her therapy today but while I was out my 24 year old idiot son took 7 of my prescribed tramadols, I’ve made him throw up already but he still feeling dizzy and nauseous . What can I do or should I take him to the ER?

  55. If I only take 25 mg. of tramadol @ bedtime for severe sciatic nerve pain, is it safe to have a 6 oz of wine at coctail time – 3:00pm?

  56. I’ve just started taking tramadol slow release for chronic pain as I have fibromyalgia.
    I’ve only been taking it for 3 days and I feel so rough . I’m sweating ,feel sick,very shaky feel as if im going to faint ,very unsteady on my feet every time i stand up i feal like im off balance is this side affects just because I’ve just started taking them and once ive got used to
    Them it will stop .I know it’s only early days but the way I’m feeling I wold rather stop them now than continue feeling like this.

  57. I took (1) 50mg at 3pm and then (2) 50’s at 6pm and another 50 at 9pm.
    I was fine until that last one. gradually it get hard to breathe and I got sleepy.
    Every breath was a labored struggle, as if my lungs were wrapped and squeezed in plastic.
    I finally fell asleep at 4am but my muscles ached for a few days due to the struggle to breathe.
    Be careful!!

  58. I got serotonin syndrome from this
    Med now I can’t get off Bc of the withdrawals what can I do about serotonin syndrome plesse help

  59. I have severe spinal stenosis and take 80mg oxycodone/day and
    40mg oxycontin/day for total of 120mg/day. Yesterday I used a
    mechanical snake to clear toilet congestion due to sudden release
    from constipation. I’ve always had tremendous tolerance to high doses
    of medicines since my age of 24 and I’m now 66 years. I just finished
    2 50mg tablets for total of 400mg for the day and have no negative
    side effects whatsoever. All I feel is sense of well-being after yesterday’s
    intense 20 minute effort to clear the toilet and without the opioids and
    tramadol I would be in severe agony. I will however take no more tramadol.

  60. i have taken between 800 and 1200 maybe more over 24 hours for about three weeks yesterdayi had some food then later was sick and felt really ill though i hadnt been to sleep will i be ok

  61. I had 9 tramadols during the night last night.
    I couldn’t sleep
    I haven’t done this before
    Today I’ve been dizzy, nausea vomoting no blood etc
    I’m too embarrassed to tell anyone my husband included

  62. Saturday night I came home with a headache and asked a family member for ibuprofen. I misheard them and thought they gave me Tylenol turns out it was tramadol and I took all 4 50mg pills at once. I felt the affects about an hour later and I was shaking and my breathing was a little off. I’m used to tramadol because I have my own prescription but I typically only take 1 since they make me loopy. I’m better now but I wanted to know if there are any after effects I should be concerned about?

  63. I have been prescribed 4 x 100mg tramadol for 2 weeks by an ortho dr in my local hospital emergency department for intolerable pain when my foot is touched where orthopedic screws were placed to repair an unstable foot 5 weeks ago. I have 10 days left in the plaster cast which was changed at that appointment. I have a history of complex regional pain. I am taking the 100 mg every 4 hours. I am also taking bisoprolol 2.5 mg daily and fluoxetine 20mg daily 2 anthistamines for clexane injection (dvt prevention) allergy. I have noticed I feel incredibly sleepy and fall asleep for 5 hours – 5 pm to 10 pm today and want to sleep all the time, I twitch in my sleep – various body parts, my breathing is slow, I have a constant headache, I feel sick and I am finding I am constipated. I also feel very quiet, find it difficult to engage in conversations and feel low in mood. Is this dose and timing of taking the meds 4 hourly not right for me? It is giving the pain relief but it is making me feel unwell. Thank you for your help.

  64. I am in severe gabapentin wd. I am about to have surgery and the pain is beyond imaginable. The nerve pain is so. Bad I took. 80 trams in 6 hours. Last dose at 11:30, 6 hours ago. Dose before that 13 hrs ago. Had no idea how slowly time was passing. Got the gabapentin, took it. Main problem now is the breathing. Anxiety. Dad and mom died a month apart.
    If I can see how the GABA helps I should be ok, right? Gabapemtin makes me feel like I can’t breathe because lymph nodes swell so bad.80 50mg in 66 hours not 6. All spaced out mostly 3 or 4 at a time. Every 3 hours. Most I took in 1 dose was5. I am sitting up on oxygen. 2 liters. Breathing is better. Seriously did not do on purpose. Will never do anything like that again.

  65. I took one tramadol 50mg. I feel really drowsy and my breathing is very shallow I’ve fallen asleep twice but have jumped awake during my sleep with my breathing. What should I do. Will this pass ?

  66. Concerned about my Mother, Nursing home in Ohio , she’s 107, was doing good until a bad fall early DEC, received six stitches of the head( no bleeding internal etc. ) and she broke four rubs, she went back to the nursing home after a week in the hospital, Now under Hospice, the Doctor has her on Tramadol and also Morphine * every two hrs ) I call her dally , mostly she’s out of it, get a couple words out of her then she off to sleep again, they also have her on oxygen, I feel she’s being over dosed on both drugs, Dr. said earlier the Tramadol is to slow her breathing, as deep breathing would affect the ribs, pain etc, but the same time said she’s not on morphine, lied to me, she is on morphine, please help me, she’s a strong lady , don’t need to die this way.

  67. Hi I’m a little concerned about a friend who said they tool alot of mixed tablets 3 days ago. They seem fine and look normal but I guess I wanted to know how bad the Kong term affects would be if they mixed tramado ( even a small dose) with alot of other medications and alcohol.. is it possible that they could react days later or if they seem fine after a few days then there ok. Just wanted some information. Thanks

  68. I have been taking between 1200 – 2000 mga per day for about 4 years. I really want to get off the drug but I am very addicted ? Any help

  69. I accidentally took 6 tramadols at once…I had a migraine thought it was Tylenol and took them I’m only 100lbs will I be ok? What should I do?

  70. I’ve taken 250 mg tramadol and 3 x 500/8 Co-Codamol all at the same time.

    Will the co-codamol in combination with tramadol increase my seizure risk?

    I’m 100kg (220 lbs) male.

    1. Hi, Johnboy. I suggest you consult a pharmacist about your concern. Usually, doctors prescribed tramadol in combination with paracetamol.

  71. Hi there I am 19 yrs old and a addict of chain smoking and weed smoker I started using tramaol 3 yrs back and use to have tramadol capsule 10-20 with mixing other formula I have been addicted to it unknowingly and increased dose day by day as I feel good about it but after that I increased 500 mg 20-40 capsule irregularly as addiction I don’t used proper diet so due to dehydrated I got piles and I once overdosed 6 month before due to over 50 caps including trama cotizine and devomine I loss consciousness and I got sever back pain don’t know in unconscious I don’t know what happened but when I got right I felt sever pain and suffering from back pain months and bit got recover again when I used 36 tabs I got overdose and admitted to hospital next day but still back pain kills I am afraid that it would destroy my life so I am in search how to get recovery and return to my normal life I want to be recovered I hav passed +2 I use to do job but due to addiction m hopeless and depressed I got recovered from piles and still a bit back pain want to be changed how could I get normal?

  72. Hi I just swallowed 2 50mg ans627 pill and drank a few sips of beer before I read online not to take with alcohol. I’m not drinking anymore but do I have anything to worry about? I don’t take these often just with pain on occasion

  73. I have migraines and had a particularly rough 3 days. I took an average of 3-4 tramadol a day and 1/2 of relpax (40 mg) each day for the last 3 days. today I didn’t have a headache but am horribly light headed, dizzy and nauseous. I have tried to eat but couldn’t keep anything down. I am not sick in any other way. I feel like you do when you get car sick or pregnant, neither is possible at this point. If that is it, I just want to be careful going forward. this is a horrible feeling to not have any other symptoms.
    thank you

    1. Hi, Alex. If you don’t feel well, call the Poison Control Center at 1-800-222-1222 for an assessment of overdose risk, or call 911 ASAP.

  74. I’m planning on taking 76 50mg pills crushed on the 1st. Will that be enough to die from? I don’t want to go on with my life anymore.

    1. Hi, Jeff. We are here to help you, not to give fatal dosage, which is different for each person. Please, reconsider what you are going to do. Think about your family and friends… You are not alone!

  75. I’m very suicidal and I really want to die. I’m not use to taking meds and the doctor gave me Tramadol because I have pain in my hand from neuropathy. I’ve taken one pill and I woke up because I stopped breathing in my sleep. Do you think if I take 10 pills that I could die?

    1. Hi, Craig. We are here to help you. Please, reconsider what you are going to do, and think about your family and friends, and everyone who cares and loves you. Remember you’re not alone!

    1. Hi, Christine. I’m very sorry for your loss. I’d suggest that you speak with a toxicologist or a coroner or another medical professional about your concerns.

    1. Hi, Abe. Yes! If you are taking tramadol to get high, tramadol abuse increases your risk of death and overdose. However, the amount of tramadol varies from person to person, depending on previous exposure to pain medications.

    1. Hi Patrick. No. In fact, 50mg of tramadol daily is within the lower range of dosing. For many conditions, 50mg is the initial dose you are started on.

    1. Hi, Stevie. Please, STOP! And, think again what are you going to do. Talk with your closest friends and family about any problem you have. There is always a solution…

  76. I just got the autopsy report from my 38yr old daughter and it said she had 10000ng of Tramadolwhich caused her pancreas to hemmorage. No alcohol in her system but she did on occasion binge drink. Isn’t a Nanos gram a small amount? Her death was ruled an accident. Can you help me understand?

    1. Hello Paul. I suggest you call 911 because that’s a huge amount of pills. Or, maybe some friend could take to a hospital.

    1. Hey Mike. You should call the Poison Control Center on 1-800-222-1222 FREE to speak to a poison expert who will advise you on what you should do next if you are in a risk of overdosing.

  77. I have been taking Tramadol for about 10 years my doctor prescribes 4x200mg per day I recently seen a pain doctor and he suggested I use 5 Norspan as well , my doctor did this…..but should I have reduced my tramadol

  78. My friend Swallowed 7 150mg Tramadol pills to feel monged out and was worried about overdosing, she didn’t but would there of been a possibility?

  79. I take 2x 100mg SR tramadol twice a day, 2 in the morning 2 at night, but this morning I took an extra 2 by mistake will it make me ill

  80. Can you become addicted to tramadol? Because the more I take there dosent seem to be any relieveing of pain, so i just take alot more.

  81. hi..friends !! last day i ate a 15pills of 50gm in 3hours and i get high… but i think its too dangerous .. it make u feel too dazy…. not good 🙁 so… u need to dont try it plz

  82. I had taken 10-12 50mg of tramadol with a 16oz Mike’s hard lemonade 8% alcohol was up all night puking and was able to stop puking during the day. But my stomach has either been upset or hurt and still is. And get nauseous easily I do not weigh much due to not being able to eat for a few days. I never take any meds so I should not have a tolerance to pain meds. Also I have taken to many tyonal in the past and had to be in ICU for 5 days cause my liver enzymes were in the thousands. I have been getting blurred vision and having a hard time staying awake so I took an adderall to try and stay awake to make it through work. Still have not been able to eat anything. Should I be worried. I weigh about 120Lbs due to a tooth infection and not being able to eat. Thanks.

  83. I have taken tramadol off and on, more on I suppose, ever since two failed back surgeries in 2005. I am at a point where I take 15 50mg (750mg) tablets every three days, at one dose, usually mid-morning. While normal, individual doses do nothing anymore, these heightened doses give me about a day and a half of pain relief, plus positive feeling that I do not get from the anti-depressant I am taking. Reading these posts I must as how much danger am I putting myself in, and what is that primary danger. Thank you for listening.

  84. I take 4 Lorazepam 1mg daily and 10 mg Temazapam. I have also been taking 100 mg Tramadol daily for 10 months They were making me feel really ill and were interfering with my breathing. I stopped taking Tramadol two days ago and feel quite rough. How long will this last?
    I would be very grateful if you would email me and let me know. By the way, I was taking these for moderate pain and have not told my doctor yet in case he wants to put me on some other lethal pill. How would I know if I had serotonin toxicity?
    I look forward to your email. Thank you, Susan

  85. I accidentally took between 39 to 45 tramadol. Am I going to be okay??? I make up med trays for a week at a time but could not find the tray this morning. So I put today’s in Rx bottles. I took the wrong bottle.

  86. My friend’s daughter (she’s 13) has just taken seven 50g tramadol tablets and now she’s saying she’s tired, should we be worried? We cannot get her to a doctor as the weather outside is horrific and the doctor refuses to come to us.

    1. Hello Schoey. That girl needs medical help as soon as possible. I suggest you call the Poison Control Center on 1-800-222-1222 for instruction on what you should do or Call 911.

  87. I took 8 capsules in the space of maybe 6 hours, but the prescription wasn’t pescribed to me,I heard you could get a buzz from them, so I thought I was try some, I took the last one at 11 ish pm and started feeling sick and dizzy and my eyes were blurry and it’s now 8:30 the next day and I still have the same symptoms, they Havant got any better but how long will it be before the symptoms go??

    1. Hello Autumn. The main danger of mixing Tramadol (an opioid medication) with alcohol is their unpredictable depressant effects. Doctors recommend never mixing Tramadol with alcohol, since the risk of overdose on Tramadol directly increases when combined with alcohol. I suggest waiting about 12 hours since you took Tramadol to start drink.

  88. Hi , I took 1 200mg slow release tablet and 1 50mg tablet yesterday at 3 in the afternoon and then at about 6 I took 1/2 of a 200mg slow release. Since 8 pm yesterday I have been throwing up . it is now 11:56 pm on the day after and I am still throwing up. I have thrown up at least 20 times. If I eat or drink anything about 10 minutes after I throw it up. What should I do?

  89. Just chewed two 50 mg tramadol that have an 627 on it and theure little white scared im going to die from this

    1. Hi Austin. Is it your first time on tramadol? The maximum safe dose of 450 mg tramadol a day. A 600mg is not typically the clinical overdose amount, but can be risky. I’d advise you to seek doctors help and have someone drive you to the hospital.

  90. I am withdrawing off heroin i really dont want use it again but getting desperate if i take a 50mg tramadol will it just help ease my withdrawl or will it be too much as read dosage online it says take 25mg to start with but i only have 50mg tablets

  91. You CAN overdose at lower or ‘safe’ dosage if you chew the Tramadol because it’s designed to pass through liver (1st. pass effect) in other words to be absorbed slowly & NOT all at once! This is why you should NOT crush, chew, snort, inject a pain medication designed for slower release. The safety bars proposed are assumed that someone is taking AS PRESCRIBED. So yes it is very dangerous…basically playing russian roulette. I’m a BSN Nurse.

    1. Hi Mylene. Call 911 ASAP or have someone who is sober and able to operate a vehicle to drive you to the hospital.

  92. I take 6 Tramadol 50 mg tablets per day. (two after each meal) I just ACCIDENTALLY took the 5th and 6th pill 2 hours after the 3rd and 4th pill – or about 4 hours before I was due. (I was talking about refilling my Tramadol and just reached over and took the two tablets meant for the evening dose.) Anyway I am concerned thAT I WILL REACT TO SO MUCH MEDICINE IN SO SHORT A TIME. What do you think?

  93. Hello my gf took about 15 tramadol pills last night around 11….50mg each..i didnt know till this morning about it she woke up with dizziness. .headache. ..and nausea. ..did the effects pass or will they get worse?

  94. My gf took around 15 tramadol pills last night 50mg each i didnt know till this morning…she woke up dizzy and with alot of nausea. …she response to me…when i talk to her….she said she took them at 11 last night. ..did it pass or will it get worse

    1. Hi Maan. You should be ok, but seek medical help to prevent major health risks and dangers. Please ask someone to drive you to the hospital or call a taxi.

  95. I took 150mg adolonta at 6 am for pain relief first one then 7hours later another one straight away I begun to feel sick hot and sweaty dizzy and just wanted to sleep I have severe c.o.p.d. I take two litres of oxygen 16hours a day,it has now been 24hours since I took the last tablet and I don’t feel any better I was sick once I do get confused and still want to sleep. Please help I don’t feel I can leave the house.

  96. I have never taken tramadol before and took one of my dad’s 300mg pills and cut it in half. Big Mistake. I got very dizzy and nauseas. Puked all night, 5 days later i still feel kind of weird, but am getting better with each day. Will I eventually be back to normal or can there be long term permanent effects?

    1. Hi Jojo. Effects will eventually subside and you will go back to being normal. But, please never attempt to do anything like that again.

  97. My partner took 250mg slow release tramadol at 5am, at 10am he was sweating extremely and then vomited all over the kitchen floor and now keeps dropping off to sleep

    1. Hi Ann-marie. Please get him to the hospital as soon as possible. He may need to get his stomach pumped and receive medical treatment to prevent organ damage.

  98. If one takes anywhere between 8-20 tramacet tablets all at once,what sort of complications may occur,is it enough to overdose?Could one die?

  99. Hello, I had total knee replacement and was prescribed Tramadol HCL 50 MG. I misread the dosage on the info paper and was taking 2 tablets every four hours for three days. That amounts to 600mg per day. The bottle said to not exceed 400 mg per day. I am concerned as I started to get the cold sweats, nausea, no appetite and am very restless and get VERY little sleep at night and a feeling of despair.

    Is that a result of the tramadol. Also is there permanent damage? Will that cause a chemical smell in the nostrils? ANY help you may provide me would be Greatly appreciated as I am very concerned. Thank you for your help and concern, Louis

  100. I took tramadol of 100mg with marijuana and the thing has been disturbing my brain since three months now.what will I do to get better from this mess I led myself into?thnks

  101. Ive been on tramadol around 8 weeks or so maybr a little longer,i really want to stop taking it i was on 400mg a day at first due to really bad back pain i still have bad pain snd i take 2 10mg amitriptyline to help at night,ive not got my self down to 100 mgs a day now plus the 2 other night tablets so im coming off real slow but its bloody hard i can tell you,i wouldnt touch it again if i ever come off it,and i say to every one STAY AWAY FROM TRAMADOL,its a drug hard to get off

  102. I acknowledge that I have an addiction to Tramadol and that if I don’t have some in my system I can’t sleep. Tonight I took 400 MG in one shot; I had done the same thing earlier in the day. My question is: What is the time range that the Tramadol will have the maximum affect on my body’s systems? Usually I get loopy at the 2 to 3 hour mark and then it drops off. I want to come down off what I took today . It’s time to start tapering off and being responsible for my health.

  103. Hello MsLadyC. Call the Poison Control Center at 1-800-222-1222 for medical advice. You need a professional assessment and directions on what to do for your son.

  104. What are the side affects of a 13yr old who takes TTramadol 50mg, he’s approx 5’6″ and weighs 100lbs. Need answer now..

  105. Hello Simon. You can Call the Poison Control Center at 1-800-222-1222 to talk to a poison expert. It’s a free over-the-phone assessment of the risk of ODing. The poisn expert will also provide advise on what you should do in case you need medical help.

  106. Hi, i have worked out i have taken 16 Tramadol and 2 codeine in the last 12 od hours feel due to pain finally managed to get some sleep for the first time in about a week but feel high and a kite 🙂 almost drunk and a bit sleepy and a bit sick, breathing ok should i go and see someone or will the drug go on its own accord and how long would it take,

  107. Hi Renee. It’s best to get medical help. Even if you aren’t in big trouble and it may seem as “just puking” you are at high risk of dehydration. Can someone drive you to the ER. You may need a saline infusion.

  108. I have taking 5 tramadol I believe 325mg each..its the 3.25-325 I believe. .well im really sick throwing up like every 20 mins..should I be breathing is fine..I juat cant stop puking

  109. Hi Cassandra. Call the Poison Control Center at 1-800-222-1222 for an over the phone assessment by a poison expert and to make sure if there is a real concern and what you should do in case you need medical help.

  110. Hi, I took 250mg of tramadol today over about a 6hr period. I’m pretty sure I’m ok as I’ve had a high tolerance for it in the past, but wanted to get high tonight due to family stress. I just want some assurance I’ll be ok. I shouldn’t have taken this much, I have a problem and need to get back to NA asap. I took some yesterday, just 100mg and got super high. Today it wasn’t working. So I waited, took 100mg more, then I just popped one more 50mg then regretted it. This is typical for me… I’m out of town, but will head to an NA meeting when I get home. 🙁 Not a fan of my addiction issues. Am I ok for now? I don’t feel anything other than calmer than earlier and a little headachy. Yesterday it was the itching and euphoria, today a couple of itches and and a headache. I have a pretty high tolerance for opioids and I do this to myself.. I just don’t want the family to find me dead in the morning or end up in the ER (again) for an overdose. I wish I didn’t do this.

  111. I have a friend who has taken 2 of these tablets at once (At least I think) Ive started to get a lot more worried and decided to do some research.
    Hes 14 – 15 years old and 6″2ft (tall for his age) In class he was acting very strange and kept seeing things. I have no idea who he got it off because were in school, hes too young to have it on him, but regardless I really care about my friend and I dont want him to die and I have no idea if his parents know

  112. Hi Gab. We suggested calling the poison control center since it’s a free helpline and you can speak to a poison expert to determine if you are at a risk of overdose and what actions should be taken next. I guess you are fine if you’re feeling better today, but it’s not wise to ever take such amount of tramadol again.

  113. Hi i took 6 tramadol a two days ago and felt high and numb also took 10 today cause of my chest pain just wondering if I need to go see a doctor of possible overdose I don’t seem to have many symptoms I’ve only felt really tired and my pupils have enlarged and my breathing seems to be fine. Please help

  114. Hi Sandra. You will be ok. But, you need to get examined by a doctor as soon as possible. How are you feeling now?

  115. yesterday i suffered severe back pain, it got worse in the evening, by this time i had drink more than a bottle of wine maybe 7 or 8 glasses. when i went to bed i took two tramadol of 50mg each. this morning i was so dizzy when i tried to stand up that i threw up. i tried to go to work but i am still feeling very sick and dizzy. will i be ok? i feel very drowsy still and sick

  116. i took 2 50mg of tramadol at 3.30 this afternoon at 9 this evening i started feeling like i couldnt breath proper its now 1 in the morning and still feels like i am shortning of breath

  117. I just took 6- 50mg tramadol (because I read 300mg is okay) but the pain from my gallbladder attack still feel severe. I have naproxen and hydrocodone can I take this too? Last time I had an attack I only had to take 4 to experience relief. I almost felt high and went immediately to sleep, and the next day I did not want to get up the whole day. This time no change,no relief, no anything!

  118. Trmadol can be very addictive , I initially took them for severe sciatica after slipping my discs in my back, the pain I’d relatively mild now, but I continually take 2 50mg 3 times a day , mainly for the high it gives, my tolerance levels are good and I feel I need to take more just to get the same effect, can’t get off the damm things

  119. Hi I was prescribed to take trimafol 50 mg two every six hours along with 500mg penicillin and also naproxen I feel really faint I did not fallow doctors orders when he said to take two I have only been taking one I’m not an addict never have been and I never take any kind of pain reliever nothing no aspirin no advil non of that but I feel really sick can’t get out of bed and really scared and don’t know what to do

  120. Hi there, I have been taking tramadol for 2 1/2 years, 100mg in evening and 50mg as needed in daytime for pain. Tonight I had taking my 100mg dose at 6p. At 10;30 I went in to take my neurotin and elavil and was talking to my husband while I did this, so was not paying attention and opened and took 2more tramadol. Do I need to be worried? I have taken this much in a 24 hr period before but only occasionally, but consistently take 100mg dose daily. I am skipping neurotin and elavil tonight as I don’t want to add to any problem. At the moment I do not fell any side effects, and attempted to vomit the accidental dose up to no avail. Please advise, thank you

  121. Hi Erin. This is a good question. Both of these medicines can increase the level of serotonin in your body. High serotonin levels may cause changes in body temperature, blood pressure, muscles and behavior, and lead to a Serotonin Syndrome. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

  122. Hi there I take 200 mg daily of tramadol and recently started 40 mg of fetzima I am nervousness that I might get serotonin syndrome are these combined doses enough to cause this syndrome?

  123. Hello Aaron. While the maximum safe dose is 450 mg tramadol a day, be carefull and look out for overdose symptoms. It can risky if you have no tolerance to tramadol. So, just in case, you should have the number of the Poison Control Center 1-800-222-1222 in mind.

  124. Accidentally took 3x 50mg over a 2 hour period. Took the first forgot I did and made dinner, an hour later I took one and hoped an extra would help me sleep. Is 150mg taken like that too much?

  125. Hi Jack-a-Roe. It’s probably a good idea to Call the Poison Control Center on 1-800-222-1222 for a free and over-the phone assessment of the risk of overdose and advise on what to do next. If the situation worsens don’t hesitate to Call 911.

  126. I just took 5 50mg tramadol pills (250mg total) each spaced by like a half hour to an hour. I have no opiate tolerance and am feeling the effects really hard. Is it possible to overdose at this amount? If so, what should I do?

  127. I was taking the maximum dose and made a mistake and went over. I experienced the shallow strange breathing and shaking legs, weird weakness -so frightening. I stopped and started over the next day at only 2 (the amount left over for the 34 hour period). I kind of evened out and I went back up to taking 6 or 7, now tapering off. I’m miserable, exhausted, scattered and frightened. I have chronic back problems due to a very badly curved spine, but I am ready to try any alternative to opiates now.
    I’ve taken 6 today and if I am going to sleep at all I need to take 1 or 2 more. I plan to get down to 5 later in the week, but right now the drop is too fast. I’m afraid that having dropped the dose quickly will make me have that weird breathing, and it is truly one of the most terrifying thing I have ever gone through. I’m looking for any advice at all about tapering. Thank you so much for your help.

  128. hello i took 150 mg at 10am later at 5pm i took another 3 50mg breathing has not bn comprimised its 140am now and my heart rate bpm is 55-60 bpm pulse feels really faint should i be worried my bpm r never this low im usually in hihg 80s for bpm im just lil scared i threw them aal away i woke up in middle of night around 12am at 47bpm

  129. Hello ab. I’d suggest that you call the Poison Control Center or the Emergency Room ASAP. Then, you may want to visit a counselor with experience in treating family addiction. Taking nine (9) tramadol pills at once is an indication of a problem. And you can benefit from learning ways to stop enabling and to set boundaries with your husband.

  130. I just came home to find that my husband took 9 37.5-325 tramadol. He is recently detoxed from narcotics. Been clean for about months. He is allergic to tramadol too, makes him vommit. He is a heavy man about 265 pounds. Breathing seems shallow.

  131. Hello Ika. I’d suggest that you call emergency medical services ASAP. And/Or the Poison Control Center at 1-800-222-1222.

  132. The last year I have been having bowel problems which was causing a lot pain in the stomach. I was prescribed 50g 4 times and day . Today within a few hours I have taking 16 50g pills to cope with the pain. Is that safe? I fell extremely tired and my body fells funny. Have I done any long term damage ?

  133. Recently I damaged a tendon on my rotator cuff (shoulder). My doctor prescribed 100 Tramadol 50mg caps, one to be taken 4x a day. I’ve been following the course religiously. Stupidly last weekend at a BBQ I drank a few to many beers (very stupid). Admittedly my prescription is not high, but I did feel very sick and sleepy as well as swetty, I took my self off the Tramadol for a few days. It’s only now (a few days later) that I’ve started the course again because of the pain in my shoulder.
    Have I done myself any harm with my stupidity ?

  134. I have tramadol 50mg prescribed by dr for horrible back pain… today in a 6 hour period I have taken 150mg total because of my pain…is this too much? will I be ok?

  135. Hello Adrian. Withdrawal cold turkey is not necessary when you can step-down doses using a tapering regimen. Seek supervision and a tapering calendar from your prescribing doctor for help.

  136. Hi there. I am taking 800-900 mg of trams a day.. For my pain.. It is not working as much as it was before.. But I love trams and there are very good on putting me to sleep.. I do want to come of then . Do u think I should go could turkey .


  137. Hi Tim. Stopping tramadol cold turkey can provoke seizures or other medical complications. You’ll need a tapering schedule from your prescribing doctor and a plan to withdraw over the course of several weeks.

  138. What happens if I stop my addiction cold turkey? I have been addicted to Tramadol for the last 3 years. I am taking anywhere between 700-900 mg daily.

  139. Hi Barb. Thanks for your question. 450 mg of tramadol per day is generally agreed upon as the “safe limit” for this opioid. While your husband may well be experiencing increased tolerance for tramadol, there are other opioids out there that may be more effective for him. Talk with him and his prescribing doctor to try alternative pain medications at lower doses. Too much tramadol can cause serious health problems at relatively low doses of the medication.

    Best of luck!

  140. hi. i was wondering what would happen if a person took 750mg of tramadol in a 24 hour period, daily, for several weeks? My husband has been doing this and he says its because he has a tolerance to opioids but I am concerned that he is taking dangerous amounts.

  141. I’ve been taking tramadol for recreational use for awhile back in June I took 20 at a time and an hour later I woke up in the hospital family think I had a seizure. What do you think happened?

  142. Hi nonah. First it sounds like the breakthrough pain you’re experiencing requires some stronger doses of short term opioids. Check with your doctor for more options and alternatives.

    While 150 mg tramadol may seem like a lot, the effect to your central nervous system will be related to how opioid naive your system is. If you’d been taking tramadol regularly for a week, or so…this dose may not have as many adverse side effects than if you’d taken it without any exposure to tramadol.

    I’d suggest that you call your prescribing doctor, a pharmacist or the Poison Control Center 1-800-222-1222 for more information and a professional medical opinion.

  143. ive been in a lot of pain due to a kidney infection. my doctor prescribed me tramadol, which doesnt do anything. ive even taken oxycodone and that didnt even releive the pain. today i took three 50 mg tablets of tramadol in less than an hour, is that too much? im also on antibiotics and antidepressants. im having side effects now but the pain is still there. i want to be sure that i dont overdose i just want the pain to be releived. is this a safe dose?

  144. Thank you for the response. To let you know I tried the 150mg dose and was not comfortable with the side effects. I felt “drugged”….it was too much. I am starting to think that Tramadol probably is losing some effectiveness…like you suggested. I’ll address it with my doctor. Thanks again.

  145. Hi Patrick. It sounds like you are describing the phenomenon of increased tolerance for tramadol. I’d suggest that you discuss the trend with your prescribing doctor. It may be necessary to change opioid medications to another pain killer such as hydrocodone or oxycodone to address your needs. OR look into other alternative pain treatments.

  146. Hi. Question…..I take Tramadol for a chronic pain issue. Currently I take 100mg 3x a day. That dosage is no longer addressing my pain very well and I’m thinking about upping my dosage to 150 mg 3x a day. I’m pushing the daily max on that I know. I’m concerned about that and I’m also concerned with taking 150mg at a time. Is that ok?

  147. just been to docsafter a bad night.8 nonths ago i was prescribed to take 200mgs tram twice a day,this i did. pain did not go away went to hosp a&e three weeks ago they told me to up the dose to four times aday which i did also they said it would be good to take paracetamol at the same time cut to the chase yesterday norn i felt bad so went to docs he took me off them and gave me codine, ok,since teatime yesterday have had areally bad time back to docs today he then realised that i was taking double the dose (800mg)so i have been killing myself for 3 weeks so its now cold turkey for xmas and not roast beef .by the way these were prolonged release tabs

  148. Hello amanda. This is a question for your pharmacist or prescribing doctor. Can you get in touch with either of them ASAP?

  149. hi i have taken 5 50mg in two days along with two500mg naproxen and one 20mg omepsules and two prochlorperaz 5mg .i feel sick i have been sick i feel faint shaking hot and my hart feels fast ,what can i take at home to stop feeling like this.till i can see my doctor monday,i will not be taking them again ,got them given on 7th 09 12???

  150. Hi Sandra. This is really a question for your prescribing doctor or pharmacist. While it seems logical to take an extra 50 mg tramadol for the cross-over pain…you’ll need to get a medical OK before you start dosing like this.

  151. Hi I took 150mg slow release tramadol about 4 hours ago I have really bad sciatica ATM and in a lot of pain tempted to take 50mg quick acting tramadol to try take the edge off. Is it ok to mix the 2 types without getting an increase in side effects?

  152. Hi Mike M. From what I’ve read, 450 mg is about the daily limit over 24 hours for safe dosing of tramadol. I’d suggest that you contact emergency services ASAP and follow up on a possible overdose, especially if any overdose symptoms are present. And then contact your prescribing doctor ASAP to ask for more information on daily limits, or to seek other options for pain management if you are taking tramadol chronically for pain.

    For what reason did you take 750 mg tramadol in the course of 14 hours?

  153. I think I’ve taken 12 or 13 50mg tablets over the course of the day. I’ve been taking 300mg of tramadol a day for about a year. Is 750mg too much over the course of 14 hours?

  154. Thank you for your prompt reply.
    My dads pain specialist who is totally against the use of tramal is the one who made this comment. He wants to put him in rehab and slowly take him off them. It did frighten us all.
    Thank you very much for your response.

  155. Hi Kula. “Poisoning the brain” is a rather loose term. Tramadol and other opiates and opioid prescription drugs are known to change the way that the brain functions during use, and for several months afterwards. But I have no knowledge yet of permanent brain damage done by medicines like tramadol. You can search the internet using this search term to find recent studies and publications based on research about the long term effects of tramadol on patients using tramadol for pain control: long term effects tramadol

  156. I take 200mg tramal twice a day for severe pain as I fibromyalgia.Plus 45 mg endep at night t help with sleep.
    I do not respond to any other medication.
    I can not function, work or have any normality of life without these medications.I have been on these for 5 years.
    Tried reducing and not as good.
    I am told this will poison my brain with continued use.
    Is this true?
    Is there an alternative?

  157. Hi Yao Ming. Yes. At 200 mg tramadol, you are well under the 450 mg daily safe dose recommendation. But taking tramadol recreationally is really not safe.

  158. I chewed 4 50mg ANS 627 tablets, 2 at once, and then 2 more two hours later. I didn’t feel the effects from the first 2 for about an hour and a half even though I chewed them, and the second 2 I chewed took about an hour as well.
    Also, not sure if it’s related, fapped to porn for more than an hour and couldn’t get off. It’s not been more than 6 hours since the first 2, and about 4 1/2 hours since the second two, I passed out earlier for about an hour because I was so drowsy, it was late anyway. Am I going to be alright? Most places I looked at about the drug said it doesn’t really do much that you can feel, but from what I’ve had, you obviously can

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