Saturday September 20th 2014

Can you overdose (OD) on Wellbutrin?

Yes, you can OD on Wellbutrin.

What can you do to protect yourself from an accidental Wellbutrin overdose? In this article, we’ll explore that question in more depth, along with the risk factors for Wellbutrin overdose. At the end, we invite your questions about Wellbutrin and overdose.

Can you overdose on Wellbutrin?

Yes, you can overdose on Wellbutrin. Because this antidepressant is usually indicated for long-term use, you will develop a tolerance to Wellbutrin over time. Therefore, increasing the frequency or amount of Wellbutrin you take in order to achieve the same effects as before is an easy way to unintentionally overdose on Wellbutrin. This is why Wellbutrin should only be taken in the doses recommended by your doctor.

Taking Wellbutrin in an attempt to “get high” – which is not a typical side effect of the medication – can also result in an overdose. In fact, Wellbutrin abuse can always pose the risk of adverse side effects. For example, mixing alcohol and Wellbutrin increases your chances of having a seizure.  And keep in mind that if you’re looking to snorting Wellbutrin good high, snorting Wellbutrin probably doesn’t get you high.

What happens when you overdose on Wellbutrin?

The most common complication of Wellbutrin overdose is seizure. Wellbutrin can also affect the liver when taken in high doses, and causes dangerously high blood pressure. Wellbutrin abuse can also contribute to mental disturbances and psychotic behavior.

How many Wellbutrin is too much?

No more than 100 mg of Wellbutrin should be taken at a time. Although it’s possible to overdose on Wellbutrin, the safe dosage is much lower than what would be toxic. At doses higher than 450 mg per day, Wellbutrin can cause seizures and other serious side effects. The fatal dose of Wellbutrin is fairly high - between 5.4 and 9 grams. But even though Wellbutrin stay in your system for weeks after use, duration of action is around 6-8 hours, which requires normal dosing of 3-4 times a day.

Wellbutrin overdose help

A Wellbutrin overdose prognosis will depend on a number of different factors, including your own size and body chemistry. Because the results of Wellbutrin overdose can be so unpredictable, it’s best to see a doctor as soon as possible after you think you’ve taken too much Wellbutrin. If you experience any symptoms of seizure while taking Wellbutrin, even if you haven’t overdoses, you should seek medical attention immediately and discontinue the medication.

Overdose on Wellbutrin questions

If you have any questions about safe amounts of Wellbutrin in your system, please leave them here. We are happy to try to help answer your questions about Wellbutrin, and will try to respond with a personal and prompt reply for all legitimate queries.

Reference Sources: DailyMed Drug Label: Wellbutrin
PubMed Health: Bupropion
Hazardous Substances Data Bank: Bupropion Hydrochloride

Photo credit: VinothChandar

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19 Responses to “Can you overdose (OD) on Wellbutrin?
kathy reed
2:56 am February 16th, 2013

I was told that 450 mgs of wellbutrin which is what I take daily will cause high anxiety. Is this true

1:50 pm February 18th, 2013

Hi Kathy. This is a question for a pharmacist. I’d suggest you call or walk in for a consult with your local pharmacy to evaluate your personal risk of increased anxiety.

Pam
6:12 am June 25th, 2013

Pharmacy gave me the wrong dose wellibutrin xl instead of wellibutrin sr which I take 2 times a day. for 5 days I have not slept. I feel very nervous and sick is this common

6:52 pm July 1st, 2013

Hello Pam. I’d suggest that you speak with your pharmacist as soon as possible to report the symptoms and seek possible answers. Yours is a question for a medical professional.

Sara
2:16 am January 18th, 2014

I overdosed a lot on welbutrin, Benadryl, Advil, Tylenol, and other medications for a year. I stopped overdosing but ever since my welbutrin overdose my legs always been restless, my heart rates not been normal and Ive never felt “ok” what should I do? What could happen?

9:38 pm January 18th, 2014

Hello Sara. I’d suggest that you consult with a medical doctor or seek a referral to a neurologist. Best of luck to you.

curtis
10:59 pm April 17th, 2014

ive been snorting wellbutrin and getting high on
this drug for about 1year how baddly well I
withdrawl if i stop taking this drug.is it safe to
stop. &how long will the withdrawls last..I’m
thinking about quitting.

Edward
8:37 pm April 20th, 2014

I overdosed a week ago with Wellbutrin 100mg, I took 30 pills and with it I took Lamictin 50mg 60 pills. All I’m left with is a few flashes from hospital and other than that I can’t remember things since the OD, is that normal?

Dominic
10:53 am May 28th, 2014

My wife took 60 300mg bupropion she’s in hospital now will she be ok

Eduard
1:46 pm May 28th, 2014

Dominic if I have at look at my experience then she should be ok as long as you responded in time and the doctors treated her right, she will however be very irritated and moody when she wakes up and whatever you do, don’t let them put restraints on her. it will make her more angry. just support her and show her a lot of love, but don’t treat her like she is damaged. My heart stopped while I was in hospital and they gave me adrenalin and CPR and electroshock. but I eventually came back by myself. so don’t give up on your wife.

Nicolette
9:08 pm June 20th, 2014

I’m on 200mg a day and today I passed out for a second, then I thought I was going crazy, couldn’t control my facial expressions and couldn’t stop my stomach from contracting and tensing up now my body is all achy …it’s Friday I will call my Doctor on Monday. Do you think this could be from the Wellbutrin?

Ivana @ Addiction Blog
2:31 pm June 24th, 2014

Hi, Nicolette. It’s probably a good idea to consult your doctor. Actually stomach cramps, feeling restless, and being unable to focus thoughts are some of the many possible side effects from Wellbutrin. What did your doctor say?

Rachel
4:16 am July 6th, 2014

I accidentally took 400mg of the generic Wellbutrin (Bupropion), which is twice the dosage I’m supposed to take daily. I now have a horrible headache and loss of appetite. Will I be okay?

Ivana @ Addiction Blog
9:25 am July 7th, 2014

Hi Rachel. You can call the Poison Control Center at 1-800-222-1222 for a free, over the phone assessment of your risk of overdose or for further help and instructions.

Irma Jiminez
3:54 am July 17th, 2014

My daughter (34) has been taking welbuterol 150mg bid for 10 yrs. tonight she accidently took 2doses. I hr apart. Forgetting that she had. Already taken one.

christine
11:45 am August 4th, 2014

my family member tried to commit suicide by taking her whole bottle of wellbutrin, . The effects are awful. While she isnt dead, she is left with non stop terrible tremors almost like a non stop seizure. She is hallucinating alot and non making any sense verbally. The hospital is not sure how much of this is going to be permanent. Please dont ever take more of this than you should, because this is worse than being in a vegetative state.

David
8:14 am August 7th, 2014

I should stop this but if I get a chest pain like almost some punches you in chest during high is that normal? I did do this many time the most I ever took was 23-25 it was scary to see what I saw. Don’t OD on this drug guys you will see stuff that’s moving trust me I seen it but it’s not there for example. I woke up because I saw I herd stuff on my ceiling. water drops falling onto my bed and I saw hermit crabs and a lobster and months spiders voices every wear I even. I feel death guys… Don’t OD……… Also guys it’s a type of high that makes you want to go away… I need talk to my med doc soon about it I’d want to od anymore but don’t want parents to find out.. DON’T OD ! The sh*t I saw is all real scary sh*t…..

Heidi
7:45 pm September 5th, 2014

Dominic, can you update us how your wife is and what symptoms she had experienced. I found my brother deceased 4 days later after a large ingestion of 300mg bupropion tablets. My family and i want to know what he went through before his death. maybe you can give us some closure if your details matched what we know. thanks. Heidi

Regina
11:11 pm September 6th, 2014

Hi!
Can I drink couple glasses of Vine after 12 hours taken Wellbutrin.
Thanks ins advance.

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