Saturday November 29th 2014

How much oxycodone is too much?

How much oxycodone is too much?

Oxycodone doses always start low and then gradually increase as your body’s tolerance to opioids builds. But how much oxycodone is too much will depend on a number of personal factors, including your medical condition, your age, your current exposure to opiates or opioids and other medications you are taking.  If you are getting high on oxycodone, risk factors for possible overdose increase.  More here on how much oxycodone doctors prescribe, and a section for your questions about oxycodone dosing principles at the end.

Oxycodone strengths

The available strength of oxycodone will depend upon what type of time release oxycodone you take, and whether or not it is combined with other medicines. Sometimes, oxycodone is prescribed in immediate release form and has a duration of action of 3-4 hours. Other times, oxycodone is prescribed in controlled release form, which increases duration of action to 12 hours. Still other times, oxycodone is combined with other non-steroidal analgesics like aspirin or acetaminophen.

1. Generic immediate release oxycodone – Generic oxycodone tablets are available in strengths of 5 mg, 15 mg, or 30 mg.

2. Generic controlled release oxycodone – Oxycodone controlled release tablets are also available as oral tablets. As a generic tablet, this opioid analgesic can be supplied in 10 mg, 20 mg, 40 mg, and 80 mg tablet strengths.

3. Brand name oxycodone formulas – Oxycodone is also found as the main pain relieving ingredient in brand name drugs. One of these drugs offers time release oxycodone (OxyContin addictive qualities are of particular concern). Another offers oxycodone and aspirin (Percodan). While still another combing oxycodone with acetaminophen (Percocet snorting also increases risk of overdose). The available strengths of oxycodone in each of these brand name medications follow.

OxyContin = 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 80 mg, 160 mg
Percodan = 4.8355 mg
Percocet = 2.5 mg, 5 mg, 7.5 mg, 10 mg

How much oxycodone is safe?

This question is a little difficult to answer.

The amount of oxycodone that is safe for you depends on your body’s current exposure to opioids. The starting amount for people who have never taken opioids is different than those who are already on opioid therapy. And doses will depend upon whether oxycodone is in immediate action or controlled release form. Furthermore, as doctors increase doses, they consider a number of different variables.

Immediate release oxycodone safe dosage

Starting doses of immediate release oxycodone for opioid naive people start low. People who have not been exposed to opioid analgesics are usually started on immediate release oxycodone hydrochloride tablets in a dosing range of 5 to 15 mg every 4 to 6 hours as needed for pain.

As with any potent opioid, doctors then adjust the dosing regimen of oxycodone for each person individually, taking into account medical history, especially as pertains to analgesic pain medications. Doctors pay particular attention to current daily dose, the degree of opioid tolerance, general medical condition and adverse side effects when increasing dosage.

Controlled release oxycodone safe dosage

Starting doses of controlled release oxycodone in opioid naive people are conservative. Doctors usually prescribe a starting dose of 10 mg of oxycodone controlled release tablets for people who require continuous around-the-clock therapy for an extended period of time.

And as with immediate release oxycodone, if a person is taking opioid medications prior to taking oxycodone, doctors factor in the potency of the prior opioid relative to controlled release oxycodone in order to calculate total daily dose (TDD) of oxycodone. As a guideline, the total daily oxycodone dose for controlled release tablets can usually be increased by 25% to 50% of the current dose at each increase, once every day or two.

How much oxycodone can you take at once?

Again, the answer to this question will depend upon how opioid tolerant your body is and how much/what type of opioids you are currently taking. There are, however, a few guidelines doctors follow when dosing oxycodone. Doctors know how long it takes for oxycodone tablets to dissolve in the stomach, release drugs to the bloodstream, and reach the brain. So not only does oxycodone dosing take into account the general metabolism of the drug, but doctors also consider a person’s weight, how long they’ve been prescribed the medication, and what other medications they are taking.

Immediate release oxycodone single doses

It is important to follow prescription guidelines for immediate release oxycodone tablets to ensure safe dosing. Because immediate release oxycodone effects wear off 4-6 hours after use, these tablets are taken as needed and dosage strength and frequency are both important to follow in order to avoid toxicity. Single doses of immediate release oxycodone start at 5 to 15 mg every 4 to 6 hours and are increased according to need and doctor discretion as opioid tolerance builds. So safe dosing for opioid naive people is between 5 to 15 mg of immediate release oxycodone at once.

Controlled release oxycodone single doses

Single doses of oxycodone controlled release tablets are designed to provide longer term pain relief over a period of 12 hours. But controlled release oxycodone tablets SHOULD NOT BE GIVEN in doses greater than 40 mg to people just starting oxycodone. Instead, A reasonable initial dose of oxycodone controlled release tablet in patients who are not opioid-tolerant is 10 mg every 12 hours. Furthermore, 80 mg and 160 mg tablets ARE FOR USE IN OPIOID-TOLERANT PEOPLE ONLY. Safe dosing of controlled release oxycodone starts at 10 mg but always occurs in doses of less than 40 mg at once for “beginners” and then increases as opioid tolerance builds. Low initial doses are also indicated in special patient populations (older than 65, liver and kidney problems) and in people taking other central nervous system depressants.

How much oxycodone to overdose?

Toxic levels of oxycodone in the system can cause your breathing and circulation to slow to the point where you heart just stops. Oxycodone overdose can occur by simply taking oxycodone too frequently or in too much quantity. But overdose on oxycodone can also occur by taking oxycodone other than prescribed (chewing oxycodone, snorting oxycodone, injecting oxycodone). When abused this way, these routes of administration change the way oxycodone act in the body.

Abuse of any kind of oxycodone poses a risk of overdose, but especially the controlled release tablets. When you facilitate the immediate release of a controlled release form of oxycodone (OxyContin) and crush/snort/inject the pills, a 12-hour dose hits the central nervous system all at once. In fact, thousands of deaths due to oxycodone overdose have been reported annually with abuse and misuse of Oxycodone HCl controlled release tablets. So if you are chewing, crushing, inhaling, snorting or injecting crushed oxycodone tablets, you put yourself at risk of oxycodone overdose.

How much oxycodone is fatal?

As with the above questions, the answer is relative to how tolerant your body already is to oxycodone, opiates or opioids. However, a single dose of controlled release oxycodone greater than 40 mg, or total daily doses of of controlled release oxycodone greater than 80 mg, may cause fatal respiratory depression when given to people new to oxycodone. And to repeat, abuse of any kind of oxycodone poses a risk of death. Both immediate and controlled release versions of oxycodone are meant to be swallowed. Chewing, crushing, snorting or injecting oxycodone leads to rapid release and potentially fatal doses of oxycodone in the body. So snorting, inhaling, chewing or injecting oxycodone (especially controlled release versions) can kill you.

How much oxycodone should I take?

This may sound obviously, but you should take the amount of oxycodone prescribed to you by your doctor. Your doctor understands your medical history, knows what other types of medications you are taking, and understands the way that oxycodone works in the body. So, follow your doctors suggestions. If however, you think that you are taking less or more oxycodone than you should, only adjust doses after a clinical evaluation. Self-adjusting doses of oxycodone is not recommended and can trigger unwanted side effects, including withdrawal symptoms and/or overdose.

How much oxycodone questions

Do you still have questions related to oxycodone dosing? Please leave your questions below. We will be happy to respond to you with a personal and prompt reply ASAP.

Reference sources: U.S. Department of Veterans Affairs: Criteria for Use of Controlled-release Oxycodone
Daily Med: Oxycodone Hydrochloride
Daily Med: OxyContin
Daily Med: Percocet
Daily Med: Percodan
NIDA for Teens: Facts on Drugs – Prescription Drug Abuse

Photo credit: zhrefch

Leave a Reply

83 Responses to “How much oxycodone is too much?
johnny rodriguez
7:03 am March 18th, 2012

i have question i need a good answer to how long does it take for oxycodone to leave the system i had to go to the hospital for my back cuz i wrecked my dirtbike and that was three or four days ago on a wed afternoon at 12pm they gave me shot and a perc not sure the mg so it is now sunday 3am when the doc sent me home he fave me acouple different meds to get at the pharmacy but they were non narcotic and they werent helping the pain so my girlfriend had some perc 10 325s and ive been taking them i have probation meeting monday at 930am i dont know if they r gonna test me the paperwork from the hospital says nun about the perc they gave me so ive been takin the percs now from wed 3pm to sun 1am i have probation at 930am monday will i be clean or will i test positive and if so should i go to the hospital and ask them for sum paperwork that says they gave a perc while i was there so basically i have been takin 6 perc 10/325s for three and a half days will and i got one and a quarter days hope u can make sense of all this please get back to me thank you very much

1:10 pm March 19th, 2012

Hi Johnny. Thanks for your question. Oxycodone stays in your system and can be detected in a urine screen for about 1-3 days after last use. It will be helpful to get the paperwork from the hospital about the prescription they gave you, but it would also be helpful that you disclose using your girlfriend’s Percocet RX, as well. I know that it’s difficult, but honesty is the best policy, especially if you are on probation for drug related issues.

martin
8:45 am July 31st, 2012

Hello.
I was givn oxycodone hcl for pain releif for my severe leg fracture..intructions say i can take 1 to 2 pills every 4 hrs as needed…for the first few days i was taking 2 as directed..then eased off over the past 10 day to eventually 1 every 6-8 hrs….now i havent taken one in the last 24hrs…but the side effects of hot/ cold sweats and cold clammy skin are still there. How long should it take for these side effects to ware off?
Thank you for your help

12:55 am August 1st, 2012

Hi Martin. Thanks for your question. I hope that you are doing well in your recovery from a severe broken leg. That sounds very difficult.

It sounds like you were taking enough oxyocodone over the 10 day period that you have developed physical dependence on oxycodone and are going through withdrawal. This is totally normal and an expected course in opioid pain medication treatment. The symptoms of opioid withdrawal usually peak 72 hours AFTER YOUR LAST DOSE. If the symptoms become unmanageable, seek medical advice and ask for alternative treatments that can help minimize the discomfort. Symptoms can linger for about a week, or so, after last dose. But you should be through the worst of it after the first three days.

Does that help?

Danny
11:27 am September 30th, 2012

Hello. How long can a person take this? I’ve had one back surgery and now bone spurs in my neck. I’ve been taking 4 a day for the last 6 years. Every year when I have all my yearly stuff done my liver is fine. What about the stomach? If something was wrong would it show up in blood test? Can you take this for years and years. I must work and cannot miss work. Thanks

2:44 pm October 1st, 2012

Hi Danny. The answer is – they don’t know yet. Long term studies on oxycodone are few but you can track them by searching for the following keyword terms in your internet browser:

site:.gov oxycodone “long term” effects

Also, what does your prescribing doctor say about your concerns about your stomach? Also, if constipation is a problem be sure to take fiber supplements or eat tons of fruits and veg – constipation can lead to significant problems such as hemorrhoids in the future.

kyon
1:06 am October 9th, 2012

hi
i had a surgery on my knee and for med take gave me oxocodfine. it said to take 1 to 2 every 3 hours. and the lady who prescribed these to my mother asked if i was a big boy she said yea, shes like then give him 2 every 3 hour. i got surgery on a wed took pills for wed thuesday friday then sat morning i took my first pill of that morning, then afterwards i started panicking for no reason crying, anxious, depressed. my stomach groelling for no reason. like for an hour i was ok then after all of them wud bother me in different ways. i stopedd taking the pills the second i the side effects. today is monday, been 3 days sence i took last pill, shudnt everything be out my systerm now cause i styll get worried then cry cause i keep thinking mentaly wrong. they prescribed 30 pills in 2 and half i took 30 cause of the pain.
is my body reacting like this because of this side effects? if yes how lonf well it take to wear off wen its already been 3 full days?
thank you much

1:39 pm October 15th, 2012

Hi kyon. So you’re concerned about the mental health symptoms that the pills seem to have provoked? Well, oxycodone DOES act on the psycho-emotional self and can affect feelings as well as the way we think. It is possible that the stress of the surgery itself has created these feelings. I’d suggest that you see a doctor as soon as possible to describe the symptoms and to seek possible pain relief alternatives.

Ron
12:11 am October 21st, 2012

I have to take two 5mg/325 actem everyday. I usualy take them in the evening so it can relieve my pain when i am asleep. could this be fatal if done for a long period of time? will my liver suffer from this dailey dose..can my heart stop when i am asleep? or am i just over reacting? I am male 6 foot 220lbs and i am in the gym every day.

7:28 am October 22nd, 2012

Hi Ron. Not a lot is known about the long term use of opioids in pain management, and its effects on the liver. It’s true that opioids complete most of their primary metabolism int he liver, so therefore, it makes sense that long term use would impact the liver. But I haven’t been able to find any research on this question, yet.

In terms of dosing…oxycodone does slow breathing and slow the heart. Are you prescribed the two (2) doses of oxycodone at the same time, or to be taken separately? And what does your prescribing doctor say about dosing at night?

liz
3:15 am October 26th, 2012

I got an order for oxycodone 5mg po one tab po bid prn. This first time I got from the pharmacy it said on the pill bottle oxycodone 5mg hcl, now this time I went to a different pharmacy and bottle says oxycodone 5mg imm rel, are they the same? the look different and thicker, I know different pharmacy companies manufacture them and they have different writting? Im scared they are not the same.

9:23 am October 28th, 2012

Hi Liz. Don’t worry. Here’s what it means on the label.

5 mg hcl = hydrochloride
5 mg imm rel = immediate release

They are the same chemical (oxycodone) in different packaging.

Ron
1:08 am November 9th, 2012

I had major wrist surgery. My guess i will be in pain for several months as it was a SL full tear . 3 month of PT. Is it safe to take one or 2 5mg of oxycodone a day or one xycontin 20mg 12 our release for 2 or 3 months straight? I do take Aderall for ADHD and Lamictal for Bi-polar 2 and my orthopedic knows this.
Thanks,
Ron

11:22 am November 15th, 2012

Hi Ron. After repeated, daily dosing of OxyContin … your body will develop physical dependence on oxycodone, which means that you will go through withdrawal symptoms when you discontinue use. This does not, however, mean that you will necessarily become addicted to OxyContin. However, you might ask for alternative pain medications which do not contain opioids, opiates, or other narcotic pain relievers if you want to avoid a potentially uncomfortable detox when you stop.

Jamie
2:23 am November 16th, 2012

my coment is this my pcp is giving me take 2 5/325 percocets every 6 hours, I take them just as that no more but the thing is I feel like I’m doing something wrong when I call back every 12 days for more pills, acording to my math they should last 7.5 days right? or am I wrong. Sometimes At night I only take one thats why I call evry 12 days. Is the math right?

2:19 pm November 19th, 2012

Hi Jamie. How many pills are prescribed at a time? If you are taking as prescribed, you should need a refill of 100 pills every 12 days, or so.

Tracy
3:10 am December 21st, 2012

My daughter had bunion repair surgery and experience a lot of pain….we are in the first 48 hours….supposed to take 5-10mg of oxycodone every 3-4 hours but has breakthrough pain that tylenol is not helping with. Can she take a dose a little earlier than the 3 hours if this happens? Like at 2 hours?

9:49 am December 21st, 2012

Hello Tracy. DO NOT increase frequency of use without consulting your daughter’s prescribing physician. The break through pain may be treated by increasing dose amount instead of frequency…but you need medical advice before changing oxycodone doses (it’s illegal to up dose amount or frequency yourself).

Denise Parks
12:52 am December 22nd, 2012

My husband has torn cartilage in knee, they gave him 5mg percocet starting about 2 months ago he takes 3 times a day mostly once a week maybe 4 as his job has him on his feet 10 hours a day. Well he received a cortisone shot to the knee and this seems to be helping with pain we want to start dosing down asap, I have been administering his pills as he tends to have addition tendencies. We have no insurance and see a community doctor, they are over booked always so getting a down dosing schedule is close to impossible. If you could give a suggestion it would be greatly appreciated Thank you, also what if the shot in the knee doesn’t hold the pain down is it a problem to go up again if necessary thanks

9:53 am December 23rd, 2012

Hello Denise. Tapering opioids generally occurs over the period of a few weeks or more and following these guidelines:

Reduce daily dose by 10% every day
Reduce the dose by 20% every 3-5 days
Reduce the dose by 25% per week
Avoid reducing the daily dose by > 50% at any given interval

I think that this document can help you, too: http://health.utah.gov/prescription/pdf/guidelines/Strategies_tapering_weaning.pdf

Georgia Lewis
10:03 pm January 3rd, 2013

This is a great site. Thank you…I am on medication and it scares me but am waiting for surgery. I have been on these garbage scary pain pill for two years and they keep prolonging the surgery. Lately I have been having a dull pain under my right rib cage. Plus, memory loss. Hope to get off them soon. Thank you for the information.

Sheryl
12:35 am January 5th, 2013

I’ve been prescribed oxycondone 5 mg and 10 mg. They don’t do anything for the pain but just make me sleepy. Of course in those doses the prescription by the pharmacy can only be generic and not brand. Does that mean I need to check out a different med? I need to work and take the edge off the pain, and so it would be nice to be awake and functioning. I just don’t know what drug to try next. Demerol worked as a sleeping pill as did Norco and some patch whose name escapes me at the moment. The only one that worked in the past was the Vicodin, but since they changed the formulation, it no longer works unless I want to take something else with it and resign myself to kidney and/or liver dysfunction.

10:14 am January 8th, 2013

Hi Sheryl. If you’re too drowsy taking oxycodone, this is definitely a sign that you might consider an alternative. Before approaching your doctor, try to consult with a pharmacist. Pharmacists generally have more time and specific knowledge about opioid alternatives, and can spend time explaining to you your options. Then, you can approach your prescribing physician with and informed approach.

kasey k
2:38 pm February 3rd, 2013

My hubby has been dealing with bad back problems for a few years now, he has 4 herniated disks in his lower spine and a few other problems i have trouble pronouncing (sciatica), anyways after working is way up the pain pill ladder starting at vicoden, norco, he is now on these oxycodone 30 mgs. His doctor has him taking 1 and a half (1 1/2) every 4 hours. I guess she upped him the half because the pain was getting worst because his tolerance was going up. These are immediate release because he doesn’t like the long acting ones. This means he is taking around 250- + a day and that seems like alot to me? is that something i should worry about. Also even more scary recently i found that he was inhaling his medication, because he says it helps his pain faster? He is trying to convince me that inhaling it is better for you, and there is less of a chance of overdosing so he is able to take more?! This is absolutely wrong correct?? Is it easier to overdose inhaling this medication then taking it orally? Im really worried about him, he claims they do not effect his brain or make him high, that it just helps his pain but his dose is just getting higher and higher and now he is smoking them and ihave never heard of this, any info would be much appreciated!

2:19 pm February 11th, 2013

Hello kasey. Smoking oxycodone does deliver the opioid to the brain faster. But in terms of effectiveness, oral ingestion is definitely preferred. Smoking opioids can be a sign of drug abuse, so I’d suggest that you schedule an appointment with him and his prescribing doctor to air out your concerns. It will help to have a clear idea of what are the best practices, how he might be able to temporarily lower his tolerance, and what a long-term pain management plan can look like.

I wish you and your husband the best of health!

Audrey Taylor
2:59 am February 27th, 2013

I broke 3 ribs and the pain is really bad. I have been given a prescription for 10 mg of oxycodone to be taken 12 hours apart. About half way through the 12 hours I have very bad pain. Would it be harmful to take 2 Tylenol as a break through med around noon. I will be in pain for about 6 weeks. I am used to taking Ty 3′s so I am hoping it will be ok. Today was dreadfully painful when the oxycodone wore off. Thank you. I will be watching for your answer. Audrey Taylor

1:26 pm February 27th, 2013

Hello Audrey. Check in with your pharmacist and/or prescribing doctor. Usually, an NSAID for break through pain will be OK but it depends on the dose amount and frequency.

Virginia
10:03 pm February 27th, 2013

My grandson took Oxycodenie. He got it from a man who got it from a gynecologist per the bottle I saw!! 180 pills was the original prescription. In other words illegal. He wanted to finish college. I stayed with him for 6 weeks chasing apparent drug dealers, taking him to classes, not out of my site. I believe he got clean. He could not get a job and eventually moved back home. He has ot been able to get a job in spite of being a straight A student in high school and being a bright, happy boy. Now at 26, he is a loser don’t know if he is on anything or not. I think his btrain is burned out. He paces. Comes into my house and practically runs across the room, stops suddenly, shakes his head, and opens the fridge door closes it quickly and starts to pace rapidly. He has difficulty focusing, sometimes looks like he is shaking his head in order to clear Gorges food, can put down a big plate of food in seconds. . Stays up all night can’t sleep, has deep dark circles around his eyes. I ask for help around the house,in order for him to “earn” money, he can;t stay focused long enough to complete a task, often says what did you say., If I say put this in the back room, he will head to the back room without the object. Stand back there, then turn around looking puzzled. Breaks my heart. What is wrong? How can I help him? MD Psychiatrist? resident facility? government help? I am a senior on fixed income. Thanks soooo much.

John Rodeh
3:22 am March 4th, 2013

I take 30 mg of OxyContin every 8 hours and two 5mg tablets of Oxycodone every 4 hours as needed ( usually about 8 tablets a day).
I have Prostate cancer that has spread to my bones. I was going to try to go on disability but don’t think I can handle it financially. So I have to go back to work. I have been off for about 5 months.My job involves driving. The vehicles are usually no larger than a pickup truck. I don’t feel encumbered by my medication. But will the company doctor feel that way? What is a safe level of my medication for work?

pat nolan
12:27 pm March 6th, 2013

If one takes to much Oxycodone and becomes unconscious but then recovers, what is the likelihood of that person suffering permanent damage to an organ?

I have a friend whose 5 year old had leukemia. She was mistakenly given 100 mg/5ml instead of 1mg/ml. She was rushed to the ER and recovered but the parents wonder about the long term effects.

Thank you,
Pat Nolan

William brown
12:55 am March 7th, 2013

I am currently taking percocett 10mg as precribe by my doctoe been taking them fro 2 years had an randon drug test today by work, Do I have to worry about my job/s?

jill
1:06 pm March 7th, 2013

What would be an acceptable urine screen for someone on 30mg imm release oxycodone?

6:36 am March 9th, 2013

Hi William. As long as you have a prescription to present to the Medical Review Officer and the urinalysis shows expected levels of oxycodone in your system, a therapeutic level of Percocet will be reported as NEGATIVE for abuse.

Jill – This is a question for a toxologist or Medical Review Officer.

Peter
1:16 am March 13th, 2013

If taken too much oxycodone, how long will it take for side effects subside, sleepiness, itching etc

6:17 am April 14th, 2013

Hi Peter. From what I understand, effects of oxycodone wear off within 4-6 hours for the immediate release and 12 hours for extended release. However, check in with the Poison Control Center at 1-800-222-1222 or your local pharmacist for confirmation.

Nabb
2:53 am April 24th, 2013

I have a question which is dosage related which is not exactly the topic and would appreciate any answers.

Do Oxycodone or Oxycontin cause any type of edema? I’ve been on 6x30mg a day for over a year for 4 herniated cervical discs, facet problems and all sorts of other things and managed to reduce it to 4x30mg for a few months. Then my condition got aggravated and I went back to 5-6 x 30mg a day but for whatever reason which I don’t think is true, the pharmacy told me that Florida only allowed 120mg. per day and that patients needed to take other things such as time release versions or morphine etc.., and that while the doctors got a slap on the hands for not abiding with the law, the pharmacists were the ones who were losing their licenses over it with the pretense that “you guys should know drug interactions better than anyone and those amounts are too high”. I don’t find it credible as telling me to take Oxycontin or morphine or even methadone is not actually reducing my usage. The pharmacies are always out of Oxycodone and get very limited amounts and I believe that by not giving out more than 120 per month to certain people, the pharmacies are managing to have more Oxycodone to dispense to multiple patients. Well if that is the case, then it sucks for people like me who actually depend on it since nothing else works as does Oxycodone.

Anyway, as a result, my prescription was changed to 4x30mg per day plus 2x40mg Oxycontin to be taken 12 hours apart. While I had to literally count the minutes to my next dosage since the Oxycodone is very short acting, with the Oxycontin, I actually have to set my alarm to remind me it’s time for the Oxycodone. At 3.5 hours, my body would start shivering slowly and then I would have waves of neck pain start to come at around 4 hours. If I didn’t take it before 4.5 hours, the pain would remain until about the next time that I took a pill. With the Oxycontin I can last 6-7 hours without pain and that’s great as I intend to reduce the Oxycodone to 3 pills a day soon (after I speak with my doctor about it).

However I noticed I am getting extremely irritating ankle and foot aches as well as edema which is clearly visible around the ankles. Since I can’t find any information about swelling due to opiates, I wanted to ask if there was a way that the Oxycontin or the mixture of Oxycodone and Oxycontin may be the culprit. I have used Oxycodone for over 2 years and I have never ever had even a single side effect while the anke swelling started within 10-15 days of me starting on the Oxycontin and it’s there almost every day.

Thank you for your help.

5:15 am April 24th, 2013

Hello Nabb. This is a question best suited for a pharmacist. I’d suggest that you make a visit or phone call to learn more about the side effects of OxyContin and edema. You can also search in your internet browser for: site:.gov OxyContin adverse side effects.

Good luck!

Dave Kurtz
6:37 pm April 27th, 2013

I have been taking oxcodone 10 mg 3 x a day for the past 5 years for a shoulder problem. I have noticed that after a weeks there is some sort of cycle my body goes through where I become very tired, and sleep for like 20 hours. I know it might be withdrawl symptoms, but does anyone else deal with this sort of thing? Sleep disorder, unable to stay awake.

oscar
2:19 am May 10th, 2013

Ok my pain management doctor prescribed me 10mg oxycontin every 8 hours plus 5 mg Oxycodone IR every 6 hours for breakthru. I usually take 1 10mg in the morning with 2 IR’s and then 2 IR every 6 hours for a total of 1 10mg oxycontin and 8 5mg oxycodone IR. I ran out of my oxycodone IR. I was in extreme pain took 1 10mg then took another about an hour later. Still no pain relief so waited for 8 hours and took 1 more 10mg. waited another 2 hours and took another. still no relief. Finally took the fifth around 15 hours after the first dose. Is that too much. I figured i was taking 50 MG of oxy a day so it wouldn’t hurt me. Still no pain relief but I am freaking out

Dolly
7:56 pm June 18th, 2013

1. I have been on Oxycontin for 10years at a dose of 80 mg timed release one tablet 2 times per day, and Roxicet 15 mg one tablet 3 times a day for breakthrough medication. Is this logical for surgeries and 15 fusions in my back, that I have gone through ?
2. Also if to be reduced should this be reduced at a rate of 25% per month on both medications at once? to finish in four months?
3. What would the reactions be at that fast paced rate of removal?

11:47 am July 5th, 2013

Hello Dolly. Thanks for your questions.

1. Your doctors and pharmacist can best advise on dosage and frequency of dosing. But for multiple surgeries and pain, the dosing seems on target for an opioid dependent person.

2. Tapering depends on the person. You’ll need a personalize tapering calendar from your prescribing doctor before you start to cut back on these medications. But 25% per month is a nice, gradual taper.

3. Tapering slowly as suggested should not really result in symptoms until the last month, when you may experience the more uncomfortable symptoms of nausea, headache, and mood swings (or other symptoms). But, again, the severity of withdrawal is highly individual and with a very conservative tapering regime, you may pass through this phase without too much discomfort.

Kate
11:37 pm September 29th, 2013

I have been on endone 5mg 4 times a day for around 4 years. I feel tired all of the time and am sick of these pills, however, I am frightened of the withdrawal from the drug. What is thye worst that can occur. I am in my sixties

J Williams
4:20 pm November 5th, 2013

I’ve been prescribed 5mg instant release for long term pain from a motorcycle accident. Sometimes it hurts so much I’ll take 150mbs. I’m also taking clonazepam 1mg every four hours

James
1:57 am November 15th, 2013

I’ve been taking 2-3 5/325mg oxy a day for a year or so now and probably will continue for the rest of my life. I’m told by those around me that my mood is elevated when I’m on the pills. That has me wondering, is my boost in spirit due to the medication or the reprieve from pain? Thank you.

1:32 pm November 15th, 2013

Hello James. Hmmmm. It’s possible. What do your instincts tell you? Can you self-analyze and observe how you feel before, during, and after therapeutic effect wears off?

jody
9:57 pm December 7th, 2013

I went to pain management they gave me for first time 60 mg er Oxycontin morning afternoon 20 mg then night 60 mg midnight 20 mg is that safe and why am i still in pain

9:26 am December 12th, 2013

Hello Jody. This is a question for your prescribing doctors and/or a pharmacist who have a more detailed view of your medical history.

steve
12:24 pm December 25th, 2013

10/325 work well

Lacy
5:32 am January 3rd, 2014

I have been prescribed 5mg oxycodone for back pain and I only take it if I am having a really hard time moving as I don’t really like taking pills. My question is, I was in pain and got distracted by my kids and accidentally took two of them at the same time. Should I be worried?

Jody
3:43 pm January 11th, 2014

Had severe acc’d in 2006. Damaged left foot and ankle, but no break. Went thru numerous tests. Some were very painful. Dx-RSD. Dr. wanted to implant pain pump being a nurse(that at this point has lost my job) i said no. Put on various diff drugs,but nothing helped. As a last result went to pain management. I am so pain weary I wonder why I’m still here. got talked into a neuro- implant after some good result from the trial implant. For some reason the permanent implant is not working the same. This was the fourth sx in 5 months with him. He is prescribing percocet 5/325mg bid. I have never abused any drug and I don’t understand why he won’t prescribe a higher dose or diff drug. I use the programer different amts of time to try to come to a higher relief. The implant only gives me about 10-20% relief. I tasted heaven with that trial and absolutely do not understand this. I am even more limited as to what I am able to do. I also have interstitial cysitis that is so disabling at times the pain is so bad I can’t get in a comfortable position not to mention practically living in the br. On top of that I was dx bipolar 2yrs ago. How do I find a dr that isn’t afraid to prescribe pain meds. I ‘m at the end of my rope between the severe pain and feeling like I’m nuts. Please give me a direction to go, a dr to see(DAYTON< OHIO). I'm on disability ,so I'm limited on $. These illnesses have hit every aspect of my life. My husband is a gift from God! Any advise is greatly appreciated.

Greg
10:38 pm April 25th, 2014

I don’t understand taking 1 oxycodone (30mg) every 6 hers and telling my doctor for going on 3 years now, that I’m still in excruciating pain. He says that I’m at the highest limit and he cannot increase it. I’m never been on to take medications of any kind, until being struck on the head with about 60 labs from a height of 50 feet. I was paralyzed for 4 days and have TBI, 3 mini strokes, herniated disc in my neck all the way to my lumbar, including angular tears in my spine and much more. What the hell does it take to be pain free? I just want my life back and they say I will never work again. Does pot work? If so, I’ll move to a legalized state if that is what it takes. I have no quality of life. 3/4 of my time is in pain in bed, Any advice from anyone? I’ve never been a pill taker and against illegal drug use all my life, but I’m starting to read and explore ways to be pain free.

billy mays
9:54 pm May 1st, 2014

I am taking 1 percocet for sleep once a night.It says I can have 1 every 4 hours..I started with 40 pills and I have 25 left. . when I finish that will I be addicted?

Carol
9:17 pm May 20th, 2014

I have been taking oxycodone for years for chronic pain. My Dr. perscibed 10 mg 3x a day but I only take half of one tablet in the morning to help with the pain when i wake up. I do not want to take it any more that day if I can help it. Can I become addicted to oxycodone if I am taking only 5 mg in 24 hours?? Thank you, Carol

12:48 pm May 21st, 2014

Hi Carol. You may be physically dependent on oxycodone – but this is different than addiction. Check in with your prescribing doctor to discuss issues with an increase in your tolerance and possible alternatives. Best to you.

Brandon
12:33 am May 25th, 2014

Im on 15 oxy 5s and like 4 oxycontin time releaae Jus to take my broken neck pain away an Jus now startintto feel a bit wooZy was that enough to overdose¿¿¿

Sheila Anderson
1:12 am May 27th, 2014

In March a Dr. at the Veterans Hospital changed my pain med from Percocet 5mg 3 X daily to Oxycodone 15 mg 2 X daily. I was told to take 7mg in am and 7 mg in the afternoon and 15 mg at bedtime. This change was made as I had built up a tolerance to the Percocet over the years. I have had fusions in my neck and back and have radiculopathy and neuropathy. I now also have rheumatoid arthritis. My rheumatologist put me on Methotrexate. I was doing much better. Two weeks ago that Dr. tested my urine. I was not concerned as I have had lots of urine tests over the years. The test came back positive for oxycodone and also positive for opiates. He immediately stopped my pain meds and said I must be getting them elsewhere also because the amount he gave me would not show up the opiates. I have been in the VA system for over 36 yrs, am 62 yrs old and have never gotten any meds other than what they have prescribed. I have been in so much pain but all I can do is start with my patient advocate and complain. I talked to the pharmacist there and was told some people test positive on this dosage and some don’t. I have always been compliant with all instructions from my doctors and I just couldn’t believe this. Can you give me any info regarding testing positive for opiates on this so called low dose? I can’t afford to go out to a pain management hospital as I am on a limited income. Guess all I can do is fight it and hope someone believes me. Any help you can give me will be appreciated. Thank you.

7:36 am May 27th, 2014

Hello Sheila. Sometimes administrative mistakes happen during drug testing! I’d suggest that you request a second testing of your urine sample; clinics generally have a procedure for such cases so that secondary testing confirms the first results. Otherwise, it’s possible that your sample was mixed with someone else’s.

Awi
12:50 am June 7th, 2014

Question? Since Oxycodone like Morphine causes severe constipation especially after surgery since I have to take so much of it to relieve the pain, what can I do to prevent developing intestinal ileus, which happened to me after my Median Arcuate Ligament Syndrome surgery, which resulted in a 7 day hospitalization. Severe pain after surgery is a given and these are the kinds of meds used to relieve that severity of pain, so please help. I have to have another surgery for the same problem.

Brenden
1:48 pm June 28th, 2014

Awi, I take suboxone which is an opiate blocker and constipates “the c**p outta you”. I, having been a past pain med recipient, avoid the constipation by eating activia yogurt and high fiber cereal. Activia truly does help tremendously.

debbie
8:39 pm July 10th, 2014

My 83 year old father is on 15 mgs 3 times a day, plus Xanax and other meds for high blood pressure. I was there when a physician told him that was to much and he should not have been put on it long term. Several years now. His pain clinic doc says he needs it. My concern is he is still driving while taking it…Should I be worried?

Gen
2:46 am July 14th, 2014

I am 5’7″ 135pds.
I Am Prescribed 6-8 roxicodone daily at 30mg.
I Am also prescribed 2 ER OXYCONTIN at 80mg 2 times per day.
This is a dosage for 3yrs now.
I recently needed a “coma” panel blood test.
My number came back at 520.
Is this a normal number for what I am prescribed. My physic. And taking my regular dosages daily for 3yrs.?

Plz answer asap. I am going on vacation and need this information as I do not understand any of it.

Thank you.

kandi
5:29 am July 18th, 2014

My boyfriend swallowed at least 18-20 5mg perks like around 430am maybe 5am this morning… is he in any major danger? He has been sleeping all day n woke up just recently and ate a tiny bit of food but had to sit due to almost collapsing. Now he is back out.. he hasn’t taken any perks in a few months..what can I do??

2:29 pm July 25th, 2014

Hi Kandi. You can Call the Poison Control Center on 1-800-222-1222 for a free and over-the phone assessment of the risk of overdose. You can talk to a poison expert on what to do next. If the situation gets worse Call 911.

Francesca
1:46 am July 30th, 2014

So my doctor put me on oxycodone 5mg taking 25 Mgs a day and been on this for last 4months and now she just stopped it and refused to give me a new refill because I missed her appt. Stupid, right?! That’s what I get for having a PA doctor. But, what I’m wondering is: am I going to have withdraw symptoms? I only have enough left for 3 days so, I’m kinda worried. If I’m going to withdraw I heard it’s bad and don’t want to go through that. I’m not an addict but don’t know anything about how much you have to be taking not to withdraw.

Sheila Anderson
10:48 am August 2nd, 2014

I did get another drug test done at a local hospital that my rheumatologist ordered for me. It also came back positive for oxycodone and opiates. I have had no medication for pain since the VA Dr stopped it. As I said before, I took 7 1/2 mg in the am, 7 1/2 mg in the afternoon and 15 mg at bedtime. Total of 30 mg per day. I did not take more than was prescribed and have never abused any of my medications. This Dr insisted that I must have gone outside the VA to another Dr because I should not have tested positive. My question was….have other patients tested positive at this 30 mg dose per day. Is that so unusual since it was oxycodone and that is an opiate. I am going to fight this because as I get older and my condition worsens I am scr*wed by the system for my pain meds since he stopped them. Please let me know about this particular dosage.
Thank you.

Maxwell
12:29 am August 3rd, 2014

This is a short story of my first encounter with the opiate Oxycodone (partially synthesized chemical therein found in poppies). At the time I had experiences with drugs such as weed, mushrooms, minor painkillers and muscle relaxants.

Me alone in my house at nineteen years old (2009) and I decide to ingest two Oxycontin 40mg pills (Oxycontin is a brand name). These pills do not contain NSAIDs (non-steroidal anti-inflammatory drug) and because they are twelve hour extended release the combination makes them quite potent. As I grind 80mg worth of Oxycontin with my teeth into powder I read “Do NOT crush or chew” on the unmarked pill bottle. I mistakingly assume that these drugs are like the Vicodin I had taken before, where the bottle says take two and I can take up to six. Within thirty minutes of swallowing the Oxycontin I became very ill, was bed ridden and experienced large amounts of pain if I attempted to move. I was overheating at dangerous rates and understood that if I didn’t control the temperature my body would shut down. I couldn’t take a cold shower because it would throw my body into shock. Luckily this was a cold windy night so I opened the windows in the house, turned on the air-conditioner, and started all the fans. I stripped and fell asleep to suppress the pain (which is really bad because I could stop breathing in my sleep), only to wake five hours later throwing up. The drugs are now completely in my body and I fall back asleep. In my pain I woke up not too long after and I spent the next two days recovering. Besides the constant pain my skin had become very pale, my eyes were swollen, I was shaking, my breathing was depressed, and I had trouble functioning in daily activities. The amount of Oxycontin taken for a first time alone is considered a lethal dose, but with the addition of chewing the pills I’m not quite sure how I survived. Because I survived I felt like every other invincible teen, but now I have a huge tolerance to Oxycontin. Weeks later I’m snorting these pills and diving deeper into the dark world of drugs. This life style went on for almost two more years before I completely stopped taking harmful drugs. Now in 2014 I’m back in school and all that stuff is in the past. So hopefully my little story will help others understand the potency of Oxycodone and that it should not be underestimated.

Linda
3:24 am August 10th, 2014

My husband has been taking 180 oxycodone APAP for two years in addition to Gabapentin 120 pills per month for pain. He has a history of addiction with multiple relapses. He is an anesthesiologist, has spinal stenosis which he says causes debilitating pain, and gets his pills from a pain doc. He has lost significant weight, smokes, has a history of family heart disease, is on anti hypertension meds. as well. I know the risks involve liver damage and respiratory depression, does chronic use exacerbate. this?

Ali
6:04 am August 12th, 2014

Hello. I was just prescribed Percocet (oxycodone and tylenol) for a long term hip problem. I have been prescribed oxycodone before, but never had a problem with it. The pills I am taking are 10mg Oxy and 325mg Tylenol. I am prescribed 3 every day at noon for the pain. I took my first dosage today, and am having terrible nausea, but all of my pain is gone. I ate a normal breakfast and lunch, and felt great before and for the first hour after. It’s been almost 12 hours since I’ve taken them and I still feel terrible. Is it possible that my dosage is too much? I’m 5’8″ and 95 pounds, so I’m small for a 19 year old. The last time I was on Oxycodone, it was 2 10mg pills every 4-6 hours as needed, and I usually only took them twice a day. Is it possible that the tylenol could be setting on the nausea? I have never had a bad reaction to Oxy before, so I am concerned that maybe my doctor prescribed me too much this time.

Ivana @ Addiction Blog
3:05 pm August 12th, 2014

Hi Ali. I’d suggest you speak to your prescribing doctor or to a pharmacist. Those medical proffesionals that can help you treat the unwanted symptoms or give you some guidence, or change the dosages, so you won’t be getting any side-effects from your meds.

jaz
11:38 pm August 17th, 2014

Does taking four 5mg immediate release oxycodone work the same as taking one 20mg controlled release oxycodone. Im wondering why my dr wld want to give me 500 5mg oxycodone to take 5 times a day instead of giving me 180 20mg oxycodone 4 times a day. It just doesnt make sense. Im with kaiser and they say the only have 5mg in their formulary but I know people who get 30mg oxycodone from kaiser, so are they lying to me or am I misunderstanding something?

jaz
8:47 pm August 19th, 2014

My question is, do I have to take the suboxon? I mean is it mandatory, or shld I have an option to take it or stay on my normal pain meds? I’ve been doing alot of reading and it seems the withdrawal from suboxon is way worse than from the oxycodone. If I must be dependant on something, which it seems is the case with my pain, I would rather it be something I know works and how my body reacts to it. In my previous post, my dr has me takung 4 5mg oxycodone 5 times a day (gave me over 500 5mg oxy), instead of just giving me 180 20mg oxycodone to take 1 pill 5 times a day. I dont get it, now suboxon…..maybe I shld change dr’s….idk. I go to the docs about the suboxon on friday. We’ll see how it goes.

Stew
12:59 pm September 7th, 2014

I’ve been recently prescribed endone for a major toothache but lately the effects of one tablet ha sent done much I was prescribed 1x5mg tablet every six hours but sometimes the frequency is 2 – 3 in 12 hours I know it’s silly for doing it but how great are the dangers bearing in mind the effects don’t seem to be that strong anymore

su
12:11 pm September 14th, 2014

What is better to do? one tablet of 10 mg every 4 hours or two every 6 hours? back surgery (kyfoplasticy) recovery. Goal : to get off these pills

Anna
7:42 pm September 30th, 2014

I took 10mg of oxycodone this morning at 7am and than another 10mg at 3pm. Then at 3;30 pm had a 4 oz glass of wine with a late lunch with my husband. I then realized that the pill bottle said do not drink alcohol. Should I be worried now?
Thanks!

Ivana @ Addiction Blog
12:21 pm October 2nd, 2014

Hello Anna. It depends on your level of tolerance to oxycodone. Of course mixing depressants is never a good idea. But, you’ll probably be fine.

jaz
3:36 pm October 2nd, 2014

First let me say I belong to kaiser, that may or may not make a difference. I’m currently taking 90 mg a day of immediate release oxycodone. I’ve been diagnosed w/degenerative disc & joint disease and I’m in constant pain. My dr wants me to go to PT. I’ve gone b4, but it actually makes my pain worse. I take 15mg’s 6 x’s per day orally but find that after about 2 hrs my pain is coming back and I have to take another one in between doses which leaves me short & in withdrawal every month. My dr doesn’t believe my diagnoses should be causing so much pain but everybody is different. I have a low tolerance for pain and a high tolerance to opiates. It seems like my dr is more concerned about her license than she is about helping me manage my pain. Is there anything I can say which is medically sound or any steps I can take administrativly to get either a higher dose or something for breakthrough pain?
Please send me a reply. I’ve posted questions on this site before and have never gotten an answer or comment. Maybe I’m doing something wrong and nobody is seeing my posts…idk, hope to hear something back soon.
Thank u
Jaz

brenda
4:32 am October 23rd, 2014

i take oxycodone for pain management, my levels get tested weekly. average is usually 250-300
this week my results came in at 9000. that is crazy, i do not abuse my meds. is there a physical ailment such as kidneys or lliver disfunytionthat could cause this? how much would one have to consume for numbers to be that high? seems like that level i would be dead or in a coma, ???? pls help me

P.S. i also take tramadol and lorazapam and once in a while trazadone for sleep disorder

tonya
4:13 am October 26th, 2014

Is it to much to.take 2 5-325mg oxocodone anctempine at one time when they say take 1to 2 every 4 hours as needed for pain

christine
4:08 pm October 29th, 2014

injured back 15 years ago. have gradually increased rx in part tolerance, also pathology has significantly worsened. i take 60 mg. oxycontin in am, and 60 mg. in pm. i also take 10mg. percocet , every 6hrs. for breakthrough pain. i weigh 237 lbs.. my pain is not under control. i fold over at the waist, after a few min. of walking. on the cusp of needing wheelchair or scooter. waiting for either sx or neurostimulator, so any higher dosage, will be temporary, i hope.

Bob
8:16 am November 20th, 2014

I have a question I am prescribed 1-2 5mg Percocet every 4 hours. I have to take 3 of them to make the pain tolerable, 3 every 4-6 hours but taking that many through out the day makes my stomach feel crappie. Do they make percocets without tyelonl? Or maybe a 15-20mg pill that I’d only have to take 2-3 through out the day rather than 9 pills in a day?
Thank you
Bob

Ivana @ Addiction Blog
2:02 pm November 24th, 2014

Hello Bob. There are other pain medications you can take, that don’t contain tylenol. One would be Oxycodone, or MS contin. Talk to your doctor to seek the best solution to your problem.

Bob
6:56 pm November 24th, 2014

Ok, thank you very much for the input….. Do you know if other people have this same problem. In reference to the pervious comment I have left? I do not want my doctor think I’m trying to pull one over on him.. I just don’t like how my stomach acts by the end of the day

Ivana @ Addiction Blog
11:58 am November 25th, 2014

One of the side effects of taking tylenol is abdominal pain, especially near the liver-the upper-right part of the stomach, and YES, many have the same problem. But, it’s most commonly caused by taking too much tylenol. Could you not seek to take an alternative med? Please talk to your doctor or pharmacist and see if s/he might have some solution for your pain. Get well soon!

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