Friday March 27th 2015

How much tramadol is too much?

How much tramadol is too much?

How much is too much tramadol?  It depends.

While it’s difficult to overdose on tramadol, you can experience serious health problems at relatively low doses of the medication. This is especially true if you’re not taking tramadol as directed (crushing, injecting, or snorting tramadol hcl), or haven’t taken tramadol before. In this article we explore the various prescription strengths of tramadol, the maximum recommended daily dosage, and fatal dose of tramadol. And we invite your questions about tramadol use at the end. We try to answer all tramadol questions personally and promptly…and if we can’t, we will refer you to someone who can.

Tramadol strengths

The available strength of tramadol depends on the specific formulation you are taking and if it’s mixed with other medications, or not. Tramadol is available in an immediate-release tablet which lasts from 4-6 hours. The extended-release version of the medication is only taken once daily.There’s also a version of tramadol combined with acetaminophen, a non-narcotic painkiller.

1. Generic immediate release tramadol – Generic tramadol tablets are available in 50 mg doses.

2. Generic controlled release tramadol– The controlled-release version of tramadol comes in 100mg, 200mg, and 300mg strengths. Strengths over 100mg are only for those with a tolerance to the medication.

3. Brand name tramadol formulas – Tramadol is available in an immediate-release, 50 mg form under the name Ultram. Other brand names include Ryzolt and Ultram ER come in the 100-300 mg doses. Tramadol is also found in Ultracet, combined with acetaminophen, at a dosage of 37.5 mg.

How much tramadol is safe?

The safe amount of any narcotic depends on a person’s individual tolerance to opioid medications. Tramadol is always started at a smaller initial dose of 100 mg per day. In patients who’ve experienced more exposure to the drug, safe doses may be as high as 450 mg a day. However, this is a determination that needs to be made by the prescribing doctor, and may change over time as a tolerance to the effects of the tramadol develops.  Similarly, how long tramadol stays in your system is affected by opioid tolerance, individual metabolism and dosing regimen.

Immediate release tramadol

People who haven’t taken tramadol before will start out with a low, immediate-release dose. They’ll be prescribed 50 mg tablets to be taken every 4-6 hours for pain – but they may be instructed to only take half the dose, starting at 25 mg for the first few days, so that they don’t take more than 100 mg in one day.

After using tramadol for some time, doctors will adjust the dosing regimen for each person individually. These tramadol dosing changes take personal medical history into account, especially as it pertains to analgesic pain medications. The current daily dose, degree of opioid tolerance of the individual, and their general health will all be considered when a doctor starts thinking about increasing tramadol dosage.

Controlled release tramadol

The starting dose for controlled release tramadol is usually 100 mg a day. This provides continuous, around-the-clock pain relief for people with chronic pain. This may be increased to 200 or 300 mg a day as time goes on.

If someone has taken a different narcotic for pain before trying tramadol, a higher initial dose may be needed. A tolerance to one opiate medication can result in a heightened tolerance for other, similar medications. The doctor will have to determine the equivalent dose of tramadol for the current dose of any other narcotic that a patient has been taking.

How much tramadol can you take at once?

In its immediate release form, no more than 100 mg of tramadol should be taken every 6 hours. Those who have never used the medication before should start on a much lower dose of tramadol, however, because 100 mg may be too much. Furthermore, only one extended release tramadol tablet should be taken at any given time. The maximum dose of extended release tramadol it’s safe to take is 300 mg, because that’s the largest dosage the drug comes in. Taking two of these pills at once could cause very serious side effects, most notably seizures.

How much tramadol to overdose?

The amount of tramadol that causes an overdose depends on personal tramadol or opioid/opiate dependence. In individuals without a tolerance, of course, it will take less tramadol to overdose, but the amount is still fairly high. In general, doses greater than 450 mg in one day can cause serious health problems, including seizures and serotonin syndrome. It’s very important to follow your doctor’s advice when taking tramadol, because taking any more than prescribed has the potential to cause serious adverse effects.

Toxic levels of tramadol in the system

Levels far below the toxic dose – starting around 500 mg – can easily cause seizures and other serious health issues. But you can overdose on tramadol taking any type of formulation of the medication. And methods of abusing tramadol make overdose more likely. Specifically, crushing extended release tramadol and either snorting it, or dissolving it in water and injecting it, greatly increases your risk of overdose. When taken orally, tramadol is slowly released into the bloodstream over the course of a full day. But high doses of tramadol or snorting or injecting immediate release tramadol can result in near immediate effect of tramadol on the brain and can cause overdose, especially if more than two pills are taken at a time.

How much tramadol is fatal?

While taking more than the recommended dosage of tramadol probably won’t kill you, as mentioned previously, this practice has some serious health risks. Overdosing on tramadol is more difficult than many stronger opioid medications – fatalities have been reported at doses between 2.65 and 8.2 g, 5-18 times the recommended maximum daily dosage. So although it would be difficult for an adult to take enough tramadol to be fatal, it’s very easy to exceed the maximum safe dose of 450 mg a day.

How much tramadol should I take?

You should take the amount of tramadol prescribed to you by your doctor. Never take more than recommended by a medical professional, and only take this oral medication as directed.  Keep in mind that tramadol show in drug tests that are specific to synthetic opiates, and that tramadol use can be tracked and recorded by your prescribing doctor.

How much tramadol questions

Do you still have questions about tramadol use? Please leave us your tramadol questions below. We will be happy to answer you with a personal and prompt response, or refer you to someone else who can.

Reference sources: Toxnet: Tramadol
FDA MedWatch: Tramadol hydrochloride tablets
Medline Plus: Tramadol

Leave a Reply

127 Responses to “How much tramadol is too much?
9:45 am May 7th, 2012

Dear Dr,

I have Chronic Pain Syndrome, and almost everyday I took pain killers, I just want to know if Tramadol can be one of the medicine that it can be taken for a long time?

12:33 pm May 10th, 2012

Hello Nawaf. Tramadol is usually prescribed for the short-term (five days or less) management of acute pain. If you are looking for a medication which can help manage chronic pain, you might consider seeking the counsel of an MD who specializes in pain management.

june hinchcliffe
11:48 pm August 8th, 2012

i have been on tramadol for a year for rls. is it safe taking 200 a day?

1:00 pm August 13th, 2012

Tramadol strengths over 100mg are for people with a tolerance to the medication, which you have developed over the course of a year. While your prescribing doctor will know best about safe doses, if you gradually increased therapeutic doses over time, the 200 mg of tramadol may be the best choice for you.

Diane Purvis
11:57 am August 25th, 2012

Hi, I have been on tramadol for pain relief since having cancer more than 7 years ago. 2 x 50mg 3 tds and 1 x 200mg SR nocte. I have been ok on this prescription until I picked up the 200mg from my chemist this week and they are a completely different shape and the box says 200mg M/R but on the strip of tablets inside the box it says prolonged release. My problem is that having taken one of them last night, I feel poorly today, dizzy and lightheaded. I’m not certain if these are the tablets I have always taken. Can you help please?

5:30 pm September 6th, 2012

Hi Diane.

SR = slow release

MR = modified release

It’s possible that the formulas vary in terms of HOW tramadol is released. If you are not feeling well, I’d suggest that you contact your prescribing doctor or pharmacist ASAP and request that you are prescribed the former formula which was working well for you.

9:19 am September 7th, 2012

Thank you; that helps a lot.

12:44 am September 8th, 2012

100 mg doesn’t work anymore and I had been taking almost 200 mg 3 times a day. I’ve recently got it back down to 100mg 3 times a day but I’m wondering if I’ve somehow hurt my liver & kidneys from taking more than the maximum for about 6 months.

12:07 pm September 9th, 2012

Hi Adriannah.

There is a risk of hepatic and renal damage due to long term use of opioids, especially morphine. And chronic use of some drugs, such as heroin can lead to significant damage to the liver. Why? Because many of the additives in street heroin may include substances that do not readily dissolve and result in clogging the blood vessels that lead to the liver. This can cause infection or even death of small patches of liver cells. Plus, current or former injection drug users who inject drugs are at risk of developing Hepatitis C (HCV).

If you are worried about liver or kidney damage as the result of taking too much tramadol, you can request an HCV screen, as well as liver and kidney screens from your doctor. You’ll have to report the high dosage, however. Does this help?

10:28 pm November 2nd, 2012

Taking one 50mg of Tramadol generic a day at bed time is it adctive …Ive been taking it for almost a yr. should I stop..helps the leg and back and knee pain. Should I stop? or is it ok to keep taking it.

8:02 am November 3rd, 2012

HI Sharon. It’s possible that you may have developed a physical dependence on tramadol, but this is different than addiction. Addiction is characterised by drug cravings after you stop taking tramadol. If you have no psychological symptoms of addiction, your body may have adapted to tramadol and you will go through withdrawal symptoms when you stop taking tramadol (or significantly reduce dosage) … but this is not addiction. What does your prescribing doctor say about daily use?

5:30 am November 12th, 2012

hello. I took two 50mg earlier like around 1pm and then one after 4 hours and then i took another one. I wasn’t sure if I did took the last one but I ended taking another one. I wanted to know if I’ll be okay….

2:55 pm November 13th, 2012

Hi Melissa. So, in other words, you took a potential double-dose of tramadol at the end of the day? Did you experience any symptoms of overdose? Any slowed breathing or heart rate? Did you try to call a 24 hour pharmacist or your prescribing doctor? Before heading to the ER, check in with a medical professional by phone and see if you need urgent care, or not.

2:04 pm December 24th, 2012

I ran out of vicodin. I do have some tramadol. I took the vicodin in the morning. Is it safe to take tramodol in the afternoon?

Daniel Torres
9:34 pm January 6th, 2013

I am clean now, but for about one whole year or perhaps a year and a half I was taking 12-22 50mg tramadol instant release tablets and other than a wicked withdrawal period upon cessation. However I havent been to a doc to see if it has caused any liver/kidney damage but I dont feel bad.

1:59 pm January 10th, 2013

Hi Daniel. Thanks for sharing more about your experiences with tramadol. Withdrawal must have been difficult! If you suspect that you may have damaged your kidneys or liver, by all means, request some blood tests. Diagnostics can really provide you with peace of mind…and all you have to do is provide a blood sample!

2:40 pm January 10th, 2013

i need some advice please

Prescribed 200 mg SR tramadol per day 2 x 100mg
epilim 100mg
6-8 co-codamol per day 8/500
2 x 35 mg of lamotrigine.

And they say I am fit for work, I feel crap on these meds after a serious head injury a few years ago.

9:00 am January 14th, 2013

Hello Jon. It may be a combination of the head trauma and the medications which make you feel groggy and unfit for work. But work may be possible. Is there any vocation which appeals to you in which decision-making is not a major consideration? Any tasks that are attractive to you?

4:28 am January 26th, 2013

My boyfriend was prescribed the 50mg Ultram. He recently was put on opana instead because he was taking up to 8 Ultram a day. He didn’t feel as if the opana was working so he ended up taking some Ultram he had left because he was in so much pain. He took 18 ultrams within 2 days. The next day he didn’t take anything, but now today he has a throbbing headache and has been puking all day and had to call off work. He thinks it was just a migrane, but I’m wondering if it could have something to do with all the ultram he took within the 2 day period?

2:39 pm January 29th, 2013

Hi Danielle. Maybe he’s in withdrawal? For how long was he taking tramadol consecutively? Physical dependence can develop within a few weeks of regular the vomiting may be related to withdrawal symptoms. Hope he’s feeling better soon!

Tracy. M
3:54 am February 1st, 2013

I received a kidney transplant in May of 2011. 6 days after I received my new kidney I had a nurse who wanted to give me tylenol and maalox to help with pain and heart burn. This nurse wasn’t sure if I could swallow the meds so she took the Acetaminophen tablets (650 mg) and crushed it, mixed it with water and put it in a 10 ml syringe, then took liquid maalox and also put that in a 10 ml syringe. For some reason she injected the 2 syringes into a central line I had in my next. wondering if you had ever heard of this happening before? needless to say I lost the kidney however not without a fight of course

8:51 am February 1st, 2013

Hello Tracy. You’ll have to consult with a physician to learn more about the procedural protocols for injecting drugs, and whether or not this mixture is recommended. In general, IV administration of drugs is called for when a patient may throw up and nurse give you the medicine or other fluid as either:

1. A fast bolus, which means you will get it quickly all at once.
2. A slow infusion, which means the medicine is given very slowly over a long period of time.

Check with the supervising doctor and request medical records to show evidence of this procedure to learn more.

12:09 pm February 23rd, 2013

I take tramadol 100 once a month for fun.But each time I have a low breathing problem and things like waves coming to my head( it is just 2 hours after taking and each 20 minutes for seconds occured) and also when i take it I’ll be under stress!!!!!
Is this normal symptom of tramadol or not? Because i scare from the seizure!!!!
thanks a lot

8:32 am February 24th, 2013

i been takn tramdol for like six mons now for my lower back pain i have experience shortness of breath cant sleep at night and also dry mouth n some times i think im seeing things that not there but this the only pill that works for me what should i do …i have a problem because i have to take this pill a night sum time i take three pills at once is that ok i need answer please

2:18 pm February 25th, 2013

Hello Sharda. Great questions! I’d suggest that you report these symptoms to your prescribing doctor and pharmacist. Tramadol works differently than other opioids, and has some qualities of benzodiazepines. Perhaps a straight opioid like hydrocodone or oxycodone may work better for you. What worries me are the hallucinations, a possible side effect of tramadol. Ask your doctors and pharmacists for their opinion. You might be able to transfer from tramadol to another opioid medication.

3:30 am March 9th, 2013

Hi, I have severe pain in my arm and take paracetamol and diclofenac (today or yesterday) … tonight I decided to take tramadol 50mg (1 capsule every 2 hours … it takes total 2 pm), think you can eat about 4 capsules of 50mg per day … it should be emphasized that a year ago or so my doctor prescribed tramadol 100mg … I can take 100mg? or stay with 50mg? and if so what would be the dose.

Mary Wagley
9:36 pm March 15th, 2013

Which would be the safest pain relief-Tramadol or Ultracets?

3:33 am March 25th, 2013

Hi i have been taking tramadol hcl 50mg. the first time I ever took it I had taken one and then about 30 mins later was still in extreme pain so I took another and I felt like i was dieing. I currently take 1 3-4x a day and now since its been a couple of years it doesn’t seem to be working as much now. My question is could I take 2 of the 50mg at once, but not have that happen again or should i switch to a 100mg

2:06 pm March 25th, 2013

Hi Brittany. You’ll need to consult with your prescribing physician before increasing doses of tramadol. It’s possible that your tolerance for tramadol has increased. But never take more tramadol before seeking medical advice.

7:51 am April 4th, 2013

Hi Mary. Ultracet contains tramadol and acetaminophen. The safest option for you would depend on whether you’d like to take the additional acetaminpohen for added analgesic effect, or do well with just generic tramadol. Consult your pharmacist for more information.

Diane Hubbard
8:32 pm April 8th, 2013

I’ve been taking 2 50mg tablets of tramadol per day for about 4 months. I take 2 tablets mid day, once per day. I’m finding that about the time I’m to take them I am beginning to feel very tired. Then after I take them, after 30 minutes or so I guess, I start to feel fine again. More alert again. I’m wondering if I am becoming physically dependent upon them. I read some comments on line about withdrawl effects that sound really awful, expecially the severe anxiety that these people talk about. I talked to my Dr and she says tramadol is not addicting expect in rare occasions. How do I stop without having withdrawl sysmptom?

5:25 am April 9th, 2013

Hello Diane. Once your body is dependent on tramadol, you necessarily pass through the period of withdrawal when you stop taking it. However, you can minimize the severity of symptoms by slowly tapering down doses of tramadol over time before finally eliminating it from the body.

4:09 pm April 10th, 2013

Hi, i have been prescibed tramadol for major back pain, i have been taking this for around a month and have found it to be great help, but now this all of a sudden it has completely stopped working, do i have to stop taking this for a certain time before these will work again?


5:17 am April 11th, 2013

Hello CMARTIN. It sounds like you are describing the effects of tolerance – the need for higher doses of a pain med in order to experience initial therapeutic effects. While it may work in the short term to reduce dosage in order to experience effect, you can trigger withdrawal symptoms. I’d suggest that you take the issue to your prescribing doctor and seek medical counsel.

Maria Popek
12:30 am April 15th, 2013

I’ve been taking 50mg at night for 3 weeks due to a right knee reduction Internal fixation. For how long can I keep taking it?

3:24 am April 29th, 2013

Hello, thanks for the great info but I need to make an important correction to one thing the moderator said. While it is true that tramadol works differently than other opioids, its other qualities are in fact similar to an SSRI medication, not a benzodiazipine. Benzos treat anxiety and convulsions and raise the seizure threshold protecting you against them, while tramadol in fact does the opposite, it lowers the seizure threshold and can cause convulsions and seizures.

3:25 am May 6th, 2013

Is rapid heart rate after taking tramadol sign of an allergy? Is it dangerous?
It takes about 1 hour and then i will be ok.I use tramadol for my migraine sometimes and it is very good for the headache.But i scare from the increasing heart rate after taking until the pill is going to work.
Thank you

7:45 am May 7th, 2013

Hello mamad. Talk with your prescribing doctor about these symptoms. It’s possible that tramadol is not a good match for you to treat headaches.

11:44 pm May 18th, 2013

I have FM and i am in so much pain the figtues bad I cant sleep and the flare up are crazy my doctor perscibe this i been on them 8 months i strat out one three a day this dont work so now i take two three a day and even tho it doesnt help they lately perscribe voltern to take also i am scared i weigh 105 lbs but my body are in so much pain and even worst whe my menstrual cycle what is too much am i seizure? level or even overdose? i just want to feel normal agin and thats pain free

8:20 pm June 26th, 2013

What about Tramadol for bipolar. I bought this OTC in Bangkok for neck pain following a midface and necklift that left me with awful pulling strangling feeling that I still have 3 years later. While it did very little to aleviate my pain I did notice that it helped significantly with my mood. Suffering for years with severe depression that did not respond to anti depressants for my bipolar. I cannot get a Dr. to prescribe it here in Canada, as they deem it addictive and a narcotic. Yet I can get all the Ativan I want which seems ridiculous. What do you know about Tramadol for bipolar and it use? I take 100 mg. but if taken daily the effe ct does not stay the same. Need to miss a day here and there.

8:21 pm June 26th, 2013

BTW, I get it from my daughter who lives in BKK or when I visit. It is cheap cheap cheap.

6:58 pm July 1st, 2013

Hello Cheryl. I’ve found no reference of tramadol used medically to treat bipolar disorder.

5:57 pm July 16th, 2013

I have been taking Tramadol ER 300mg prn chronic pain and Fibromyalgia for some time. The strength seems to have lost it’s effectiveness (I still hurt alot). Should I call my Pain Management doctor and let him know? Also, how long after you take the ER does it really start working?
Thank you

11:08 am July 17th, 2013

Hi Cathy. Yes, call your prescribing doctor and describe the effects. It’s actually an expected side effect called tolerance. You can learn more about onset of tramadol and its effects here:

2:04 am July 18th, 2013

be careful when taking this it is dangerous when mixed with other medications,my fiance recently almost overdosed on this If I did not get home when I did it probably would have been the end. I can’t beleived they prescribed this for her shoulder when she is already on an antidepressant and muscle relaxer I’m told it is fatal when your taking this much doses altogether,isn’t it illegal to prescribe tremadol to someone on an antidepressant.?

12:52 pm July 18th, 2013

I want to thank you so much for your time and efforts in answering my questions about Tramadol 300mg ER. I appreciate it!!! BTW, what is a medication similar to Tramadol ER that would be an option for me to take?? Thanks

11:54 am July 19th, 2013

Hi Cathy. Other opioids include hydrocodone or oxycodone…but these can be very habit forming and even addictive. Check into all possible side effects before moving to a stronger pain killer.

Mandy Lynch
4:45 pm July 22nd, 2013

I have CKD which seems to be improving. I had to give up allopurinol, hctz motrin, and lisinopril. Is it alright to take 1 or 2 tramadol a day? I have very severe arthiritis.

9:12 am July 25th, 2013

Hello Mandy. Do you have a prescription for tramadol?

Carol DePinto
11:03 am July 25th, 2013

Which is stronger tramadol 50mg or Ultracet 325?

9:13 pm August 6th, 2013

I take Tramadol 25mg one tab three to four times a week for about 4 years now. I take it for neck and back pain when motrin does not relieve it. I just find that is works quickly and effectively when motrin does not. My question is, have I been using it for too long? And if I stop should I taper? Sometimes I have not had to take it for a week at a time here and there and I have been fine. Am I at risk for withdrawal symptoms if I never take it again?

Joe y
1:05 am August 12th, 2013

I have been taking 37.5 tremadal apap for a year about 4 pills a day my doctor says its safe but I read that it’s really short term medication but it does help,take edge off my body is completely filled with arthritis already had total shoulder replaced and back decompression surgery, so do I keep taking or stop and suffer

4:30 am August 23rd, 2013

i’ve been on tramadol 200mg for 8 year i take 2 a day for Chronic Pain Syndrome,i want to stop taking them. i haven’t talked to my Dr yet.. what i want to know is i’m 52 what will happen if i stop taking them,i’m sick of taking tablets my back neck kills me every day but i just want to stop them..

marie sandford
1:11 pm August 27th, 2013

I have been taking 25 a day for several years.i have had about 5 u think someones body gets used to the doses x

2:13 am September 22nd, 2013

I have a question. I just started tramadol a few days ago and 2 50mg made me so sick and I felt awful. I cut the dose in half and take 25mg and I really get no relief for my rupture disk. Can someone help me? I had taken Ultracets and they worked great but, the tylenol level made some changes in my liver levels and I do not drink. Help!

5:07 pm September 24th, 2013

Finally straight answers.
Yesterday I got 100mg tramadol tablets. First time ever. Once I got home. unthinking, I took two, not the one I was supposed to. After the anxiety attack, ten hours, and 5mg Diazapam, I’m back in pain but dare not take another, would it be safe to take 500mg paracetamol or ibruprofen with codine in it? I just dont want to make myself feel even worse

5:11 pm September 24th, 2013

Oh I dont know if this makes a difference but they were also slow release, and I made a typo, they are 200mg tablets, not 100mg

11:25 am September 26th, 2013

Hello Keiran. Codeine and tramadol are structurally and chemically different types of opioids. I’d suggest that you consult with a pharmacist for advice and suggestions on dosing, especially given the extreme anxiety tramadol seems to have provoked.

12:52 pm September 29th, 2013

I’m 16 and took 6 tramadol 50mg at 7pm last night am I ok?

Raynor Clarke
11:57 pm September 29th, 2013

I’m taking Tramadol 100mg SR twice a day,I took 100mg last night at 9pm,then another 100mg this morning at 7:30 am.. Then realized I had taken the dose an hour and half early..hope I haven’t done any harm to myself

1:33 pm October 2nd, 2013

Hi Monica – Call the Poison Control Center for an analysis – 1-800-222-1222.

Hi Raynor – You should be be OK with an earlier than normal dose, but monitor yourself for symptoms of slower breathing, or heart rate and call the Poison Control Center should you become nervous or want clarification.

7:07 am October 17th, 2013

I have been taking tramadol for a few years now.I have to take 150mg at a time in order to get relief but it can last 8+ hours before I have to take another dose.In a 24 hour period I might take 150mg 3 times a day.Is that too much??

4:34 pm October 22nd, 2013

Hello Dana. This is a question for your prescribing doctor and/or pharmacist. We are not qualified to provide medical advice but, instead, refer you to the appropriate medical professional.

5:37 am October 23rd, 2013

Thanks for the advice, I got the second opinion you suggested after I ended up calling an ambulance, because I started not being able to breath the panic and shaking was so intense, and discovered that giving Tramadol, in any strength or release method, to somebody with an acute anxiety disorder was possibly the single *STUPIDEST* thing my (now EX) GP has EVER DONE.

If you suffer from a nervous or anxiety issue, tell your Dr. to shove it if he tries to give this stuff to you, every nurse and doctor I have mentioned it to here in hospital (for an unrelated issue) has told me it is BAD NEWS.

5:26 pm October 26th, 2013

I take 2x100mg in the morning and 2x100mg at night ,I have been taking the tablets for yrs are they safe ?

11:20 pm October 26th, 2013

Hi. I’ve been taking Tramadol for a couple of weeks but I can’t swallow tablets and they taste very bitter. To get round this I’ve been snorting 200mg instant release tablets and also inserting 600mg up my anus 3 times a day. Although it’s really helped with my depression I’ve found I’ve been extremely constipated. Do you think this has anything to do with anally inserting the tablets?

12:54 am November 5th, 2013

Rupert Your anus? Would you care to eloborate as to why you would take this drug in this way?

1:32 am November 16th, 2013

I’ve been addicted to painkillers since I was at school I started off with a couple of Solpadol.Then I began taking a couple more,and more and after about a year or so I would take a strip of 10 at a time.But after around a couple of years I found I was still getting a buzz but I was having to take about 15 solpadol’s at a time and even then it would only last for a couple of hours.So I started taking Tramadol the first time I took 4 30mg capsules and I got a subtle buzz that lasted for a few hours,After a couple of months though I was having to take more to get the same feeling until just like with the Solpadol’s I was taking a strip of 10 30mg capsules at a time.That was about 4 years ago though and up until 5 days ago I was getting through around 60 30mg capsules of Tramadol a day.I’ve stopped completely now though but I can’t stop sweating,I feel utterly awful and the last 3 nights I’ve practically cried myself to sleep,So I was actually coming online to order some more but I saw this site and I know it’ll be terrible but I’ll try to hold out for a bit longer.I don’t expect or want any sympathy I’m a 25 year old guy who hasn’t worked a day in his life were well off so I’ve never needed the money everything should be good but since I’ve stopped taking the painkillers I’m thinking what have I been doing ? I’ve been left behind all my friends have moved on and I’m still at home and not really caring because I was so heavily medicated but with no painkillers I’m having to face reality and it’s extremely depressing.(Sorry this is too long it was longer but I deleted some stuff I had written about my little sisters being spoiled brats and quite a lot of other stuff (Including a couple of funny dreams) to make it shorter sorry anyway I talk way too much. x

11:21 am November 18th, 2013

Hello David. It sounds like you’re going through cold turkey withdrawal. Do some reading up on tapering down off tramadol; basically you cut by 25% once a week. It takes longer to get off, but tapering does make symptoms less severe. Do you have support where you are for psychological cravings or physical dependence symptoms?

6:11 am December 8th, 2013

I forgot that I had take my tramadol at 10.30 pm and took a dose at 12.45pm. will it hurt me. I only take 50 mgs every four hours, been taken it for over a year and I have never messed up like this before. Pretty scared.

9:22 am December 12th, 2013

Hello Kimberly. You’ve probably developed opioid tolerance after regular dosing for a year, or more and the extra dose may not affect you greatly. However, if you notice symptoms such as slowed breathing or heart rate, call the Poison Control Center (1-800-222-1222) or the emergency services ASAP.

4:27 pm December 18th, 2013

I have taken tramadol 50mgs tablets for over eight years , the dosage is 1 tablet every 6 hours as needed, Nothing has ever changed in that eight years even though I ask, still I am guilty of self medicating to 4, 50mg tablets, (200 mg) the only way I have ever felt a physical change in pain.
The doctors have never had a problem to giving additional medications loratab 5/500 and now norco 7.5/325. I guess my question is, after reading all of this, has my medication treat for pain might have been mismanaged. I guess I feel like, too little for too long

Jillian Benham
10:58 pm January 13th, 2014

My mum has been put on tramadol she is 79 and weighs six stone and is seeing things also unsteady on her legs is this to much, and is in hospital for consterpation ?

7:58 am February 16th, 2014

I have permanently torn rotator cuff tendons in both arms, plus tendon tears in my biceps and elbows, again in both arms. As a result I have chronic pain and have been taking Tramadol for 10 years now and have asked my surgeon and Dr. what are the long term consequences of constant use. Presently I take 150mg twice a day along with Temazepam to help me sleep some nights. Can you advise what the long-term effects of Tramadol use are, apart from the usually ones?

Judy Diller
2:36 am February 28th, 2014

I have rls which makes it very difficult for me to fall asleep at night. I have been taking 10 drops of tramadex the last few night which helps me very much . Is it ok to take tramadex . every night or when needed at night. I don’t need it during the day.


1:20 pm March 17th, 2014

I have been taking Tramadol for about nine months for chronic back pain. On bad days I am to take one to two tablets( 50 mg ) every 4 to 6 hours. 2 tablets cause stomach upset, so I have been taking 1 1/2 (75 mg) daily with excellent results.However I have found that If I skip a day or two I tend to get diarrhea,and feel a bit edgy.I am concerned that these may be withdrawel symptoms.My maim question; is 75 mg daly,over a long period of time,a risky dose,and if so should I wean myself from them or simply stop?

2:26 am March 21st, 2014

Just caring bout my friend really shes in her early 30s with 2 kids, got family their just incase tonight. she says been taking tramadol and its been spacing her out and not touching the pain although her back went into spasm?
She pulled her back out by bending down and this sciatica kicked in? she can barely walk and still in pain.

She said she can have 1 life tramadol in the 24 hour period what does this mean to me?

She had 6 or 7 since 9 am this morning and is on about taking 1 more whats the risk? And if she took it what could happen as she hasn’t been knock out by the drug yet tonight?

She has taken 8 before and been absolutely fine? She wont take 10 in a day as shes got 2 kids to think bout.

Please help as this is all new to me thanks

10:57 pm April 3rd, 2014

i’ve been taking tramadol for about 10 years .for chronic pain in my calve’s.i have taken as much as 400 milligram’s a day i now take 300 milligram’s.i have had regular blood work every 6 month’s with no side effect’s. my problem now is i can’t get a doctor to prescribe 300 per day.instaed they want me to take 100 milligram’s per day and 15 mg of meloxicam per day which give’s me low back pain and any suggestion’s?

9:05 pm April 10th, 2014

I am prescribed tramadol MR for relief from chronic pain. I started off with 50mg immediate release qid about 10 years ago, but switched to the MR formulation a few years ago. My current dose is 200mg tramadol MR bid.
This morning, I forgot to take my dose. By about 6PM I was feeling so rubbish I looked at my pill minder to take my second dose and discovered that I had not taken my first, hence the level of pain I was in.
So, I took my first dose about 6:30PM. My question is, how long to I have to wait before I can take another dose? Can I take the other 200mg MR before bed (about 5- 6 hours between doses) or do I have to wait until the morning? I usually take 200mg MR at about 7AM and the second dose at about 7PM.
Hope someone can answer me soon. Thanks.

5:07 pm June 1st, 2014

How many tramadol 37.5mg makes 100mg tramadol?

antony leighs
12:14 pm June 17th, 2014

Hi I was prescribed tramadol in 2009 as I broke my hand in 8 places,i started of on 100mg an over the space of 3 years It was risen to 400mg a day,in 2013 I had a new doctor and the doctor decided to just stop this medication saying I had no use for it any more,after about 36 hours I felt so ill/sick I ended up going out an buying some off my friend I have done this for over a year an I am also buying them off the internet an because I can get them so easily I am at the point of taking 900/1000mg per day,is this dangerous?an what is the best way to stop as I have been the doctors an they are not willing to help.

4:55 pm June 20th, 2014

Is 100 mg of Tramadol a safe dose for an 84 year old that weighs 140 pounds and the person does not take any pain meds. After this dosage she had nausea and vomiting. Could that be a result of the Tramadol?

10:19 am June 30th, 2014

I’ve been on tramadol for about 2-3 years. At first it wasn’t much at all but now I take 300mg to 450mg a day. I know I’m addicted to them, I’ve tried to stop but I can’t. I get really anxious and cold sweats etc., and also because I have really bad knee injury, I am due to have a knee reconstruction within the next year. What should I do? ‘Cuz I’m a bit worried about my health being on them for so long.

3:18 am July 9th, 2014

How can I stop taking tramadol 100mg

3:33 am July 9th, 2014

How far apart should a person who has MS, that takes vyvanse for fatigue, wait before taking their tramadol?

7:17 am July 13th, 2014

My Dr.gave me tramadol 500 mg n said take 1 every 12/hrs for my abdominal pain !!! But I don’t thnk that’s enough cause I still b n pain what should I Do

Maggie Lewis
1:02 am July 18th, 2014

What is a safe amount of time between a does of tramadol and Vicodin?

10:13 pm July 19th, 2014

I am currently taking 1- 50mg of tramadol a day for very bad back pain. Can this become addictive

9:17 pm July 24th, 2014

Is 3 tramadol at a time every 6 hours safe? Any less than 3 doesnt help me.

11:33 pm July 24th, 2014

Hi, what will happen if someone took over 10 pills of tramadol 50mg at once?

3:03 pm July 25th, 2014

Hi Linda. Your body might be developing tolerance to Tramadol if lower doses that helped you achieve the wanted effect previously, are no longer effective. You can talk to your prescribing doctor or a pharmacist for advise and dosage assessment.

11:03 am August 1st, 2014

Can I take another 300 mg time released tablet after 4 hours for severe pain on a one time basis ?

9:02 pm August 1st, 2014

can tramadol cause liver damage I take 50mg 5 or 6 times aday for facial pain a nerve doctor wants me to try clonazepam looked it up and don’t feel saft with that drug

2:07 pm August 3rd, 2014

Hi Joseph. Yes, Tramadol can cause liver damage if used for an extended length of time. It can actually become very addicting as well. Plus, if you drink alcohol, you may damage your liver even more.

Dr das
8:23 am August 7th, 2014

I am dental surgeon and a long term sufferer of maigrain . I have been taking tramadol IV 1000mg at once, then it increased to 1000mg four times a day for four years, I had at least five seizures but it did not stop me. I just wanted to know what can be the damage of my kidney and other organs. I just got out of a rehab centre and I have quit taking it, but I just wanted to know what kind of permanent damage I have caused to my body

4:55 pm August 18th, 2014

I took 12 at once of 50mg and feel sick and dizzy will be okay

R V Shantanavar
2:58 pm August 21st, 2014

I met with an accident 8 months ago,due to this my left leg was fractured at tibial head regio along with compartment syndrome and operated as per the procedure.After this i was advised to take Tremadol 50- mg capsules for 10 days two times a day.,
After one month of operation i was getting serious burning sensation in my feet and it is still continuing ,so again i started Tremadol capsule 50 mg once a day after taking this my feet burning will far i have take for 5 months daily one capsule to relieve my feet burning.
My question is if i will take continuously for another 2-3 months is it safe or not.
Iam not noticing any side effects so far only i will get drowsiness after taking capsule.
kindly suggest me whether i can continue at this dose or any other alternative please.

Sandra Elliott
8:47 pm August 26th, 2014

I try to be sensible when taking Tramadol and have been using this medication on and off for about 2 years now at 50mg 3 times a day for back pain, but I make sure I have long breaks so as not to become addicted. If its for a special occasion when I need to really dull the pain is it safe to take 100mg twice a day? ie 2 50mg at once twice daily.

12:29 am August 28th, 2014

Hi i was just wondering if anyone knows if i could be hurting my kidneys or liver?i take between 40/50 50 mg tramadol about five.times a.week.i have been taking this.for about four years. at year.two i had four seziurs in a few momth period but am now on an aniti sezuire med so i havent had any of those anymore.but i wpuld truly like to stop and im just so worried i already might have damaged or hurt my body.

12:18 pm August 28th, 2014

I think tramadol 50mg is the weakest pain medication the doctor has prescribed me. i have chronic pain in my lower back from spondylolisis (pars defect) i usually take 4 of the small white tablets 200mg at one time. Im not an addict and im not intentionally overdosing. it just makes you wonder. i have two fractured vertebrae and a slipped disk. Is taking 200mg at one time fatal. im only 18 years old.

9:15 am September 4th, 2014

Would it be ok, for my Dr., to prescribe me ER, plus IR tablets?

I currently am prescribed 6 x 50mg per day.
Also take: ER Cymbalta (for depression/anxiety/back pain), Meloxicam (inflammation), Gabapentin (for leg nerve pain), Occasional Baclofen – muscle relaxer (mostly for insomnia.
My biggest complain about taking these meds, other than the fact that I still hurt all the time, is the CONSTIPATION! (any suggestions about how to combat this, will be greatly appreciated!)
I am listed as in “remission” from opiate addiction, from 5 yrs of over 160mg of oxycodone. I have chronic back pain, and can not get the relief I need from my current prescription, but prefer to never return to the oxycodone world!>>>> It was pure Hell, escaping it!
Anyway, back to my question. I am wanting to see if an ER tab, of say, 200mg plus 50mg x 6 would = 500mg (or x5 = 450mg), would be too much to approach my Dr. with?
Do you think this is something she will go for? I really think it will help to cover my pain, and keep me from returning to OxyWorld.
Thank you so much for your service!

Tracey Lane
8:31 pm September 7th, 2014

I have been prescribed Tramadol for back pain for the past 4 years and was taking 100mg 5 times a day with little effect. Dr has now prescribed Gabapentin 900mg daily with view to increasing for pain relief and has advised to continue with Tramadol but changed it to 100mg slow release twice a day. I have been showing signs of withdrawal by sweating loads and anxiety, Dr did say I could ‘top up’ if necessary with tablets I have left of the 50mg immediate release but am unsure how many and is this safe?

4:08 pm September 13th, 2014

Josie . I had bunion and toe sergery,I. Asked my sergeant to prescribe me tridural for my pain my nephew went to Jamaica was hurt badly they prescribed him these pills he made me try them that’s why I asked my sergent about them .i told him I was told there is no narcotis in he said ya gave me the prescription didn’t right the milagrams or how much to take .I went to the pharmacy he didn’t have the milagrams phoned the doctor the secretary in a hurry to get off the phone said 200milagrams and the pharmacist mistakenly wrote every 4 hours in .4 hours I took 3 for two days I was vomiting and kept going in and out of sleep for those two days I had no pain but I was so so sick be carful with them thy are very strong lasts all day

7:51 am September 19th, 2014

I just want to start taking tramadol now I bought a satchet of 100mg tabs over the counter. Is it save to take a whole tablet at once?

3:58 am September 26th, 2014

I take up to 300-350mg daily and recently tried 100mg injectable because pharmacy was out of everything but that so I tried it and it worked better with the 100 than if I took 200 the first half hour and pain free (chronic pain) now I was wondering if a capsule (50mg) can be opened and mixed with water to inject and if so will the effect be the same as using the 100mg? Reason being is the pharmacy I go to rarely is able to prescribe the tramadol for lack of stock and wondering if I can extend the supply for those times they are unable to fill the prescription.

1:39 am October 1st, 2014

My 4 year old daughter who weighs 49 lbs fractured/chipped her ankle Saturday night and the emergency room foot and ankle that was on call accidentally prescribed her tramadol 50mg. I had no idea and thankfully we did not give her any of the 2 pills they gave her in the er. I even questioned her about them being pills saying she can’t take pills and I was told to crush them up and put them in Apple sauce. Anyways my question is what would that dose have done to my daughter? We have made a complaint and they said the doctor would be reviewed, however I am furious and feel If she could have been severely hurt she should be let go. This is my daughters life.. I would appreciate your response, thank you

12:53 pm October 2nd, 2014

Hi Karen. For children aged 4 to 16 years, it’s safe to administer 1 to 2 mg/kg/dose every 4 to 6 hours (Tramadol IR). The maximum single dose a child can take is 100mg, which is what they sugested you sould give your daughter. While the maximum daily dose is 8 mg/kg/day or 400 mg/day of Tramadol.

6:08 pm October 5th, 2014

I take one tablet of Tridural 100mg once daily. However today I made an error and took two. One at 11:00 AM and another at 1:15 PM. Should I do anything?

10:20 pm October 5th, 2014

Have a presc. for tram. 1-2 tabl, 50 mg every 4-6hrs, for connective tissue, auto imm disease. I take 2 tablet a wk, next wk 2 days @ 2 tablets each day, relieves pain for 12 hrs & helps me sleep soundly ! No side effects at all, have been using it for 2 yrs, no problems, want to take it though every wk @ 2 days 2 tab so can work 1 day, I am 64 yrs old retired, but would like to work as a sub teacher pre school, & be more active. Is this safe, all professionals have told me it is safe, but am very very cautious. This would really make my life so much fuller, if could take 2 days a wk, but can manage if 1 day is better. Thank you soo much. Jennifer

12:29 pm October 6th, 2014

Hello Margaret. How long have you been taking the medication? If it’s been a while, your system has probably built tolerance to it, so you should be fine. The maximum dose allowed within 24 hours is 300mg. Just to be safe, you can call your doctor.

11:13 pm October 18th, 2014

I am taking 150mg SR Tramedo twice a day (Morning & Night). I take instant Tramedo Capsules 100mg, for severe head pain, as I suffer from disintegration at top of spine, which causes severe head pain. I also wear a stiff foam collar while sleeping to keep my head from moving side to side. Without the collar the pain is horrendous when I wake. Overall the pain is constant, it never leaves me it just intensifies at different times of the day. Sometimes I wish I had something stronger, but still be able to carry on my normal activities like driving, gardening etc. had this problem for four years now.

4:11 pm October 22nd, 2014

Hi Denis. Have you talked with a doctor about his issue? I’m sure they can do something.

1:07 am November 20th, 2014

i’m addicted to tramadol and i take 20 every day .. i find it so amazing feeling …. and now i’m addicted i want to stop it but it’s so hard .. any opinion ?

5:04 am December 13th, 2014

I had my wisdom tooth extracted and im taking tramadol (100mg 4 times a day) but i does not really help with the pain. If i take acetaminophen will it increase the effect?

4:15 am December 26th, 2014

I have severe fibromyalgia my mother in law gave me some 50mg tramadols as my pain has been awful, yesterday I took 3 as an attempt to get rid of the pain so I could get on with things, I ended up being sick all day falling asleep constantly shaking uncontrollably with cold sweats and weak all over, eventually I slept it off feeling very fragile today but okay, I have eaten and generally back to my normal self, but am just wondering if this was an overdose and if there’s anything I should do?

6:18 am December 28th, 2014

how much tramadol dose leads to death of adult

3:10 am December 30th, 2014

I had accidentally taken a double dose of 100mg tramodol a few months ago. I ended up having a seizer, am I allergic? I wasn’t sure if my body would reject it now completely and cause another.

1:40 pm December 30th, 2014

Please iWould Like To Know The Damages Involved In Tramadol Abuse..To The Liver/Kidney. iUse Everyday Beyond The Reasonable Dose Because I’m Addicted & I’ve Been Using “Everyday”, For 2yrs Now. So iWant To Know The Possibilities Of Exposing My Liver & Kidney To Severe Damage & How Long Till iBegin To Have Symptoms Of A Damaged Organ Due To Tramadol Abuse

4:22 pm December 30th, 2014

Hi Sayid. Pharmacologic use of tramadol has not been associated with cases of clinically apparent drug-induced liver disease. But since you are using above reasonable doses, it may cause liver damage. People have reported having kidney pains when using tramadol, but unless you had damaged kidneys before you started taking it, it shouldn’t cause severe harm.

12:39 pm January 7th, 2015

Hi i took two 100mg tramadol tablets at 4am this morning and since feel dizzy and have been sick. Have i took too much?

11:03 pm January 17th, 2015

My 12 year daughter accidentally took 3 of my 50 mg Tramadol tablets. Do we need to do any thing?

1:24 pm January 20th, 2015

Lisa, Call the Poison Control Center on 1-800-222-1222 to have your daughter’s risk of overdose professionally assessed by a poison exert. Or drive her to the ER.

4:11 pm January 26th, 2015

I am 70+ years old my doctor went from one 50 mg twice a day to one tab every 6 hours. Since the I have had a paralyzed diaphragm. Is a normal side effect?

1:02 pm January 29th, 2015

Hi John. I’d suggest informing your doctor about this one and any other possible side effects you may be experiencing.

tommy bishop
1:08 am January 30th, 2015

Can taking 600 mg cause kidney damage even if it was for 4 to 5 days and then 100 mg for the next 4 or 5 days then back to 600 for 4 to 5 days? I was doing this due to pain levels. I have stopped taken so much once I learned it can damage kidneys. I think it has been 2 years like this. did not know 400 mg was limit per day

3:03 am March 1st, 2015

No one will stop people from seeking suicide, they will always find a solution………:/

7:07 am March 16th, 2015

If I take only one 50mg tablet of tramadol per week for years,is this considered ok,or an addiction?

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