Mixing Wellbutrin with alcohol

Mixing Wellbutrin and alcohol can lower alcohol tolerance but it can also impair motor control, jugement and thinking. More here on mixing Wellbutrin and alcohol effects.

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Are you considering mixing Wellbutrin with alcohol? Know what can happen?

Here, we review the real risks and dangers of mixing Wellbutrin and alcohol here. Learn what happens in your body when you mix Wellbutrin with alcohol and know what can go wrong. Although Wellbutrin high is uncommon and it’s not likely that Wellbutrin show up on a urine test, taking Wellbutrin can provoke side effects. We invite you to ask questions about mixing Wellbutrin and alcohol in the comments section at the end.

Wellbutrin and alcohol effects

Wellbutrin (bupropion) is an antidepressant medication which is taken each day to help combat the symptoms of a mood disorder. In most cases, people don’t mix bupropion with alcohol in order to try to achieve any kind of high, but simply because they don’t want to have to abstain completely from alcohol while being treated for depression. Some effects from mixing Wellbutrin with alcohol which we have found in self-stated reports by users on the internet include:

  • blacking out
  • confusion
  • lowered alcohol tolerance
  • nausea and vomiting
  • seizures

Dangers of mixing Wellbutrin and alcohol

Wellbutrin has a high risk of seizures when it’s not taken as directed. Wellbutrin also chemically reacts with alcohol, having an additive effect in the body and brain when combined. So when alcohol is taken with Wellbutrin, dangerous side effects can occur. This is mainly because mixing alcohol and Wellbutrin can intensify the effects of both alcohol and Wellbutrin. Some potentially dangerous effects of mixing Wellbutrin with alcohol include:

  • dizziness
  • drowsiness
  • impaired motor control
  • impaired judgment and thinking
  • memory problems
  • paranoia or other unusual thoughts
  • suicidal thoughts or feelings
  • overdose

This additive effect goes both ways – Wellbutrin can enhance the effects of the alcohol itself. In other words, taking bupropion while drinking can lower your alcohol tolerance and cause you to become severely intoxicated with comparatively small amounts of alcohol. Alcohol is a sedative, meaning it makes you sleepy, drowsy, and lightheaded. It makes sense, then, that drinking while taking Wellbutrin can cause trouble concentrating and difficulty with coordination, putting you at risk of accidents. Plus, you are at risk of falls or serious injuries when mixing Wellbutrin with alcohol. And because mixing the two can cause alcohol poisoning or overdose, it might even be deadly.

If you are abusing Wellbutrin recreationally and mixing it with alcohol to get high…you may be facing a risk of developing addiction. But, no need to worry because help is available! In fact, there are many rehab options and treatment programs for antidepressant addiction available to help you get sober.

Wellbutrin and alcohol overdose

Doctors recommend never mixing Wellbutrin and alcohol for very good reason. First, the risk of overdose on Wellbutrin does increase when used with alcohol. These drugs enhance one another to cause much more serious side effects than normally experienced separately. Second, even if you don’t OD on Wellbutrin, you’re at a high risk of experiencing seizures when you mix Wellbutrin and alcohol.

Wellbutrin and alcohol deaths

Alcohol is one of the most prevalent drugs used in combination with Wellbutrin that can cause death. Because of the way Wellbutrin lowers your tolerance to alcohol in unpredictable ways, it’s not safe to mix the two. NOT DRINKING ALCOHOL is the only way to stay safe while taking Wellbutrin.

Is it safe to drink on Wellbutrin?

Not really. Mixing Wellbutrin with alcohol just enhances the dangerous effects of both drugs. Paradoxically, if you drink regularly and then stop abruptly when you begin Wellbutrin, this can also cause side effects. So always ask your prescribing doctor for more information on taking Wellbutrin safely.

Mixing Wellbutrin alcohol questions

Do you still have questions about mixing Wellbutrin with alcohol or other substances?  Or maybe you are interested in snorting Wellbutrin effects.  Please leave your Wellbutrin questions here. We try our best to answer all questions personally, and promptly. And if we don’t know the answer, we will refer you to someone who can help. Your experiences with mixing Wellbutrin and alcohol are also welcome.

Reference Sources: NIAAA pamphlet: Harmful Interactions, Mixing Alcohol with Medicines
PubMed: Bupropion and alcohol fatal intoxication: case report
MedlinePlus: Bupropion
About the author
Lee Weber is a published author, medical writer, and woman in long-term recovery from addiction. Her latest book, The Definitive Guide to Addiction Interventions is set to reach university bookstores in early 2019.


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  1. I drink 2 to 3 glasses of wine with and after dinner every night. My doctor prescribed Wellbutrin for depression. I will stop drinking. My question is, how long after I stop drinking before I can start Wellbutrin?

  2. If you are a regular drinker, is it best to abstain alrogether when starting Wellbutrin or wean off alcohol? When the med is in your system for a few months, can I have an occasional drink?

  3. How much alcohol is required to cause an issue with Wellbutrin? My wife only drinks occasionally, but I am concerned about that and her migraine meds causing reactions.

    1. Hi Timothy. It is not recommended to mix alcohol with Wellbutrin. I suggest that you speak with your wife about the harms of mixing these two substances.

  4. Hey I have a question I have inly took 1 100mg tablet this morning at 10:30 it’s peak is at 7 hrs after you take it I was wanting to sleep and I have no sex drive and I’m really short tempered and feel even more down. Do I just stop the welbutrun? I’m not my normal self. And I don’t like the way I’m feeling

  5. Been taking 150mg XR for 3 weeks. Until last night I was able to drink on Buproprion/Wellbutrin no problem. It was working like a miracle drug, my mood was normal and my energy was finally good. Last night I had one drink with dinner and started to feel weird right away. I was having trouble reading and lost my appetite, but nothing major. Went to bed at 9pm, woke up around 2am with very weird symptoms. Doze off, feel very dizzy, wake up frightened. Doze off, feel electric shock in my thigh, wake up more frightened. Doze off again, feel an evil presence taking over my mind, wake up terrified! I’m afraid to go asleep now, so I think I’ll go watch tv. Nope, I’m too paranoid to even get out of bed until 5 in the morning when the feelings finally pass. I almost went to the ER. I have a PhD and have never had anything like this happen in my life.

    Do not drink on this medication. Even without drinking, take it with extreme caution.

  6. I am an alcoholic. I also have been on bupropion 450mg.for about a year. My drinking is out of control and I want to go to detox. My concern is that I know the combination of bupropion and alcohol can cause seizures, detox from alcohol can cause seizures, and suddenly stopping this high dose of bupropion can cause seizures. So…where does that leave me? At this point – at home – I am very afraid of any withdrawal symptoms. I live alone. I am retired. I am 64. I’m not lacking in intelligence – I am simply a dual diagnosis clinically depressed alcoholic.

    1. Hi Amy. Call a toll-free Alcohol Helpline on 1-888-675-1820 to find a high-quality alcohol addiction treatment program. This helpline is accessible 24/7 and gives you the chance to speak with trusted treatment consultants who can help you find an alcohol recovery program suited to your individual needs.

  7. Here’s the situation, my son is on this drug for last 6 mths. He has been drinking Vodka while on this about every weekend and I have noticed that he is also increasing it to during the week.
    It HAS increased since on it and he seems to ignore that,after a increase of some strange symptoms like shakes legs when squatting, weird visions of seeing things, shakes,panic attacks, needs to walk pace etc when it all comes on. I have told him he cannot drink while on it and I will not give him a ride to the liquor store anymore to get it as he has no license and we live out in country, he is of drinking age(23). Anyways he now isn’t talking to me and says if he cannot drink then he will go to pot. Can u respond to this with all the info what it will or can do to you drinking and pot also and I will show him.he don’t take it seriously!

  8. I have been on contrave for roughly 2 years now. And I am looking to drink with some friends in about a week and a half. I have never drank while on the medicine. Will I be okay to drink for one night with my friends and now have any of the negative side effects? Would it be best if I didn’t take my contrave the day of me drinking? I want to enjoy some drinks with my Friday’s next Saturday but I am worried about what’ll happen if I do? Thanks so much!

  9. Wellbutrin and Alcohol
    I drink 4-5 ounces of alcohol most every day for the past 50 years. Two months ago I started taking Wellbutrin 100mg twice a day to assist with quitting nicotine. I have kicked the Nicotine addiction.
    My question is that since I have not had a negative reaction to taking Wellbutrin and Alcohol if I prefer to keep drinking Alcohol should I quit Wellbutrin?

  10. I have read that you shouldn’t immediately stop drinking alcohol while taking welbutrin but you should not drink alcohol while taking it!?!? I am a working mother of 2 who drinks (Not to drunkenness but daily) don’t really want to be on wellbutrin but insurance won’t cover Chantix until I have tried welbutrin to quit smoking….so what am I to do????

  11. Hi, I talk 450mg of welbutrin 300 for about a year an the added 150mg for a few months.. The past 3 to 4 weeks I have been drinking alcohol, about 5 to 9 a day… Today I’m going to quit drinking cold turkey.. is that ok?

  12. My alcoholic relative began drinking again while taking Wellbutrin and experienced auditory hallucinations then she had visual hallucinations and saw people in her house at night and people in her bed. She was taking 150 Mgs two times a day.

    I just read a bunch of your stories above I feel really sad. yOU ALL ARE PLAYING Russian rOULETTE WITH YOUR LIVES.. Please stop drinking. Here is howl Use y our phone or computer and google alcohol treatment ner your city. you can find a list of treatment centers, If you don’t have insurance just keep trying I found one place that will take you without charge . Don’t take the well butrin with alcohol. Scotch guy you are in a very strong state of denial. All who wrote drink to the point of alcoholism. Get help. life is hard but it is way better sober. ALcohol is a myth. a fatal myth.

  13. I am writing an article for a consumer magazine and am wondering how long the synergistic effects of Wellbutrin and alcohol last? For example, if a person consumes 450 mg of Wellbutrin daily along with about six drinks a day for, say, a year and then stops drinking, how long will it take for the sleepiness, confusion, etc. to subside? If this varies based on weight or other factors, please give me the range (I have already researched seizures, sudden withdrawal, death and other related issues, but just need a direct response to this one question). Thank you.

  14. So I’m 25 and about 5 ft 3 130lbs and am on Wellbutrin and Effexor. I drink socially when I go to bars or at a part or whatever. I black out when I drink a lot and never thought to look into my medicine being why. I’ve been up all night reading people’s stories from their bad side effects and I completely agree and my heart goes out to them. Drinking while on Wellbutrin is the worst thing I’ve ever done. There have been countless times when I thought I was over drinking because I blacked out but in reality I had like 5 beers. I am an absolutely different person when drinking on this medicine and everyone hates me and I even hate myself. I do irrational things and cry my eyes out, try to fight people, try to drive, it’s like my brain does not work. And then I wake up the next day and have no fucking clue what happened. It’s ruined a relationship of mine and has fucked up many more. I’ve gotten so messed up I’ve taken more anxiety pills and slept for 2 days straight. I think I was so upset I wanted to kill myself. Note I am not suicidal normally but when these instances occur I contemplate suicide seriously. I feel hopeless and so low and end up laying on the floor crying so hard for hours… that’s not normal for me. I never realized how much alcohol and my medicine has affected me because everyone just says I can’t control myself when I’m drunk and all that. I realize I can’t stop myself from drinking usually after being on this medicine. I will say okay I’ll have 5. And then I hit 5 and I’ll take one more drink and I’m blacked out. I’m young and social and want to be able to go to bars and things every now and then but the situations this medicine is getting me into makes me want to die. My latest incident my brothers gf and I tried to fight! And I don’t even know why when I try to find out what I was so mad about because I’m fucking blacked out. And want to die all day and for the next week. Just don’t do it. I don’t know how I’m going to do this

  15. I had a really dumb question.. I drank one screw driver and a big mouthful of Vodka while on welbutrin (150mg) and I was fine at first, then I started violently throwing up all night, all day, and some the next day. We noticed that it looked like there was blood in the vomit the first night. It’s been a week after. Should I still be worried about it though?

  16. I have been taking Wellbutrin for about 1year abusing alcohol for many years . I want (must) stop the alcohol abuse.
    My doctor knew I consumed alcohol every night. I told him 4 ounces of Vodka but in reality it was more like 8 ounces. He never mentioned any danger but I believe YOU. The only way for an alcoholic to stop drinking IS TO STOP and then take it one day at a time. I have been down the road once before so I know what must do. Since I have been mixing the two for about 1 year with few side effects (mostly lower tolerance and black outs) Can I stop the alcohol? I will not be back to the USA until the middle of May 2017 but I must stop the abuse now. Please give me some guidance.

  17. Hi,
    I read that you should not abruptly stop drinking while on or about to begin Wellbutrin. I consider myself a heavy drinker, about 5 drinks a day. How long should i stop drinking BEFORE I start taking Wellbutrin?


  18. Is this the kind of medication where a few glasses of Scotch will be a problem? By a ‘few glasses of Scotch,’ I mean 2-4 consumed over the course of 1-4 hours (the range really is that long, depending on the conversation and Scotch available). A typical glass of Scotch only has a few ounces of Scotch, at most.

    I don’t drink Scotch for the purpose of getting a buzz – I’m the kind of person, noted in the article, that just doesn’t want to give up my hobby entirely. Stated a different way, my question is this: will drinking ANY (even relatively small amounts as described above) significantly increase my risk of seizures (the side effect about which I’m most concerned)?

  19. I’ve been taking Wellbutrin for about three years now and am currently on 350 mg/day with 10 mg/day of Lexapro. I smoke pot every single day (I have for the past 12 years) and I usually drink 3-4x a week. I self-medicated for so long with pot and alcohol that I can’t kick it.. I know it’s a problem that needs to be addressed.

    Anyway, I don’t think wellbutrin lowered my tolerance to alcohol. I never really abstained from drinking, but I think I’m going to now (yes, on Christmas Eve of all days). Wellbutrin makes me incredibly sleepy when I start to drink on it.. I mean passing out at 9:00 pm after two glasses of wine (after a 9-5 workday). It’s also making me shaky the next day.. which is what really freaks me out. I used to get shaky when I was hungover (alcohol withdrawals) but with Wellbutrin I’m legit starting to worry that I’m going to have a seizure. Maybe I’m just paranoid. But that’s another thing–I feel like my meds just aren’t even working lately. That and I have constant headaches. I called my doctor last week to ask if I could split my pills because I was so shaky.. she said no. But we’ll see what happens when I go in next.

    As for the pot, I can’t tell any difference. But I wouldn’t be able to since I’ve been perpetually stoned since I was 13.

    This post is kind of pointless but I guess I just started pouring all of this out. Merry Christmas.

  20. Have been taking Welbutrin for few years and have always drank 3-4 glasses of wine almost daily. I have no issues with not drinking now that I’m aware of the danger. Need to know how to stop it since I’ve heard shouldn’t stop drinking abruptly while on the med. Should I just cut back on the amount slowly or is it ok to Stop completly at once? I also take Phentermine. Does taking both meds and alcohol make it worst?
    Thank you for your assistance on answering my questions.

  21. I’ve been taking Wellbutrin XL for about 3 years, and for the past 2 months I had been drinking on the weekends, and my antidepressant stopped working. My doctor said that because I drank at night and take my medication in the morning that alcohol shouldn’t effect the medication, so he just upped my dosage from 150 to 300, will that fix it?

  22. What I’m getting from this is people’s responses are all over the place. From suicidal to I didn’t notice anything. I’m at just over 2 weeks with wellbutrin and haven’t noticed a think while drinking. I’ve had over a bottle of wine in a day which isn’t rare for me to do. During that time I’m productive, doing yard work, or sometimes working on the computer. No crazy thoughts, no blackouts, no increased or decreased appetite for alcohol.

    I do want to cut down on drinking but it makes me feel pretty nice too. I wonder if I’m not noticing an interaction because I’m still early on with the wellbutrin?

    My advice would be, if you drink on wellbutrin, go very slow with caution. Inform someone and have them keep an eye on you. There are some crazy stories in these comments.

  23. I would recommend to NOT mix those two! I was taking Wellbutrin a couple of years ago for depression. I went out and had one drink with my friends. That same night, I punched my ex in the face and then jumped out of a car going 30. I would have never done this if it weren’t for mixing the two.

  24. I have been taking it for a week and am going to a party tonight and decided not to take it would it still be bad to drink alcohol today even though I didn’t take the medicine

  25. I take Wellbutrin, and I am not a regular drinker. Before I took Wellbutrin, my capacity for alcohol, measured in bottles of beer, was usually around 6-8 before I felt like I was getting drunk. On Wellbutrin I can only need about half that amount to feel drunk. You can easily drink too much and then the combination of Wellbutrin and alcohol will totally surprise you with a sudden blackout, and loss of control. Be extremely aware of this effect. It is dangerous.

  26. You won’t have any issues drinking a glass while on Wellbutrin, but don’t drink heavily. I drank a decent bit last Weekend and almost ended up overdosing. I was really angry and when I went Home I sobbed for two hours and contemplated killing myself before blacking out. I was practically a different Person. I’m never suicidal and not really aggressive in real life

  27. Hi, I feel a little better after reading these comments. I’ve been on Wellbutrin for a couple of months now. Memorial Day I decided to get a drink at 10 am. I had been drinking 1-2 drinks a night and was fine. I ended up drinking 8 different types of alcoholic beverages, got into an argument with my wife, left s party, walked to a grocery store, bought cigarette and a tall boy, wondered down a busy highway trying to get hit by a car, making and receiving phone calls that I don’t remember much about, walking a mile down a dirt road into thick 4 ft tall grass, laying in the grass, my dad ironically being able to find me, being taken to his house, running away into some woods, almost getting into a fist fight with him, calling 911 on myself, hiding from the cops in a ditch and finally turning myself in… Went to the ER and broke their alcohol level test, sleep for what seems to be forever and finally being release from suicide watch in the hospital room. I have bruises and scratches all over me, my business is on halt and one of my guys quit. I don’t think drinking and taking Wellbutrin was s good idea. Thank God I’m alive and back with my family!

  28. My rheumatologist prescribed me with Wellbutrin about 2 months ago. (300mg) I told him I drink regularly (I’m newly 21) and he said nothing about stopping my drinking while on this medication. However, I saw on the label it clearly said no drinking. I enjoy drinking and really do not want to give it up. I’ve been drinking since I started it and haven’t felt too many weird side effects with the exception to dizziness and impaired driving which have substantially decreased. Can I continue consuming alcohol? Is there an antidepressant that allows you to drink while taking it?

  29. Hi, I take welbutrin 2x day. Ive noticed if I drink alcohol I get heartburn and getting really sick…vomiting. is this because welbutrin is also used to help people Come off of alcohol.

  30. My 21 year old grand daughter from Seattle is planning a 10 day visit to see her grandfather and me. Her mother tells me that this young woman is taking welbutrin, smoking pot regularly, and drinking vodka. It sounds like a very dangerous combination. Pot is not legal in Virginia, and I do not know the welbutrin dosage, nor how much alcohol this 21 year old drinks. But I am concerned about her visit, and wonder if we can manage to have her with us, even though we love her a great deal. My sense is she is addicted to pot, and the mixture of it with prescription drug and alcohol makes me very worried for her well being. If we tell her she cannot drink or smoke while she is here, will her body go into withdrawal? My husband is 81 and I am 78 and have never had to deal with this kind of problem.

  31. Ive been taking buproprion for 15 years, and have had all quantities of alcohol with it over the years, from not drinking, to light drinking, to heavy, to binge drinking, to stopping cold turkey. I’ve never had any effect I’d attribute to it.

  32. I’ve had a very similar experience to yours. I think your reasoning is sound. Can also happen if you accidentally take 2x scrip in one day.

  33. I’ve been on Wellbutrin for about 3 months and recently increased my dose from 150 mg to 300 mg about 2 weeks ago. I’ve been able to tolerate 2-3 glasses of wine without a problem and haven’t even really wanted to drink a glass of wine every day like I used to. I had a terrible experience this weekend with drinking too much on Wellbutrin and was shocked the next morning to realize I’d had 8 or 9 drinks without realizing I was intoxicated. I never drink that much! After waking up with an awful hangover, I drank lots of water, took ibuprofen, 300 mg of Wellbutrin and tried to take a nap several hours later. As I lying in bed with my eyes closed, my whole body began to tingle and pulse and I saw hallucinations of a long tunnel, geometric shapes and faces. I opened my eyes to make sure I wasn’t having a stroke and realized that my entire conscience was altered. I walked around and felt disconnected from my body as if I had done some kind of drug that made me very high. I felt like I was floating and having an out-of-body experience. It was the most uncomfortable feeling I’ve ever had. It took about 5 hours for me to start feeling back in my body again. I didn’t think to make the connection between Wellbutrin and alcohol until later. It has been two days and I am now starting to feel like myself again. I am guessing that the strange out of body experience didn’t happen until the next day because I had taken the Wellbutrin in the morning long before I drank that night… And maybe taking the Wellbutrin the the next day while there was still alcohol in my body magnified it all over again. Who knows. Be careful!

  34. A shrink I was seeing after a deployment in ’99 prescribed Wellbutrin knowing that I had been drinking heavily since returning home. He never told me to stop drinking vodka, just to try and “cut down.” I was on the drug off and on for months or years at a time and had no side effects from the alcohol. Then in 2013, I was making dinner and blacked out, hitting my head on the tile floor. Eventually, after two hospitalizations over the next year, a neurologist told me I should never have been mixing that drug with alcohol — I was finally diagnosed as having suffered seizures. Twice during seizures when I was alone, I woke to find I had vomited…and I am one lucky person to have not choked to death. I keep thinking, what if any one of those events had happened while I was driving. Or operating power tools…or any number of other activities. I stopped taking Wellbutrin but was prohibited from driving for 6 months. And now I am dealing with major depression since my husband’s death last fall, but am too afraid to ask for an anti-depressant for fear the Wellbutrin experience could have sensitized me to all such drugs. If I had known all of this, I would have sought help with the alcohol use before ever taking Wellbutrin.

  35. Most people who have already answered this question above did not have a problem with alcohol either, neither did I. I was a casual drinker. Once drinking on wellbutrin I turned into an excessive drinker.

    If you have that one drink you are risking a lot — blackouts, weird behaviour, weird life, even when you’re not drinking. It will send your life down a dark path.

    Make a choice. Wellbutrin is good and works. If you add alcohol use to it, another drug, that’s where the problem is. It’s the interaction, not one on its own.

    Taking wellbutrin can help you eliminate depression, alcohol prolongs it and masks it. Decide what’s more important, long-term happiness or being able to drink right now. Once you sort out your depression, if you can, you can migrate off of wellbutrin and go back to drinking. But don’t do the two together.

    To answer the question, one or two drinks while you’re on it will mean you will likely get an addictive behaviour to alcohol, no matter how infrequent you do it at the moment. The answer is not going to change the more it’s asked.

  36. I need to know if anger/rage is a side effect of wellbutrin with small amounts of alcohol. I’m only on 75 mg. after doubled dose for a few years.I was still depressed, so I quit cold turkey, and several weeks later started on lower dose. I’m anxious, so higher doses aren’t an option for me.

  37. Can you have a couple drinks on this meds without worring? I don’t drink a lot but being put ion this meds and these risks is scaring me

  38. I have only just connected all the dots about mixing alcohol and Wellbutrin. I was under the impression I had a problem with alcohol and was getting ready to seek professional help for alcoholism. I spoke to a friend who recently had a bad episode due to her medicine and it got me thinking about my recent experience.
    My doctor never told me about mixing the two and I didn’t change my drinking habits in anyway. I went right along partying and socializing as I’ve been doing for the last 7 years.

    – consistent blackouts even on nights when I didn’t drink a lot
    – highly emotional and crying while intoxicated
    – sudden mood swings throughout an evening of drinking
    – sexual promiscuity (waking up in strangers’ beds and not remembering how we met or how I got there!)
    – bouts of anger and unusually angry behavior (yelled at a doorman, started an argument with the man I’m dating, picked a fight with a random person at a concert venue)
    – said things I don’t mean and would never say when sober
    – Broke my foot while intoxicated and accused a woman of steeling my shoes when she was simply trying to help me walk by removing them.
    – yelling at a tennis tournament even though I was asked multiple times to stop and then was asked to leave.
    – nearly broke a glass door and injured myself in the process of trying to pry it open

    Everyone reacts differently but i have undergone MAJOR distress because of being ill-informed. I’ve lost friends, put myself in dangerous situations, and caused injury and harm to myself.

    I’m off the Wellbutrin and contemplating a malpractice suit.

  39. My Dr told me that the alcohol reduced the effectiveness of the wellbutrin; that it tied up the same brain receptors, and being a more powerful drug, blocked the action of wellbutrin. Is that so?

  40. If you think you cannot give up alcohol to take an antidepressant that can help you greatly, then you probably do have a problem with alcohol already. Bupropion and alcohol do not mix AT ALL. It should be one or the other. Bupropion can actually cause you to want to drink more or to become an alcoholic if you drink while on it. It is your choice but taking the risk is such short-term thinking, as though that beer or wine is more important than your happiness and overcoming your depression.

    Think of what is actually important to you and make the decision that way. I find it sad that people are leaning towards quitting the medication more than quitting alcohol while on it. That shows your priority.

  41. Is it ok to have an occasional glass of wine when taking welbutrin? Is it ok to just stop taking welbutrin? I don’t think that I need it any more?

  42. I have a friend who drinks every day and has just started taking bupropion about 6 weeks ago. This person still drinks every day. I would say this person is an alcoholic. He has stopped in the past for a while but then always starts back. This person just lost someone very close to them. And is drinking so much more. They also have stopped the medication for a couple days and then goes back on it. I’ve noticed anger during this time. Then they start it back. What should I do?

  43. Glad to have found this post. I have been taking Wellbutrin for over a month now and have found myself drinking too much alcohol and feeling like an alcoholic. I’d be determined to not drink and then compulsively do so. I was drinking too much and having episodes of black outs like some of you mentioned. I would have hours unaccounted for when I’d find writings or text messages I did not remember sending. I’d have long phone conversations with friends and have no idea the next day I’d called them. I started having suicidal ideations, nothing I ever acted on, but I would write suicide notes, and spend too much time contemplating suicide. I’d spend the next displeased with myself, anxious, paranoid, with shaky hands and a rapid heart rate. I thought I was certainly messed up and thought it was me. I’m now sober and feel like myself again. I feel so much better knowing that those thoughts and behaviors were coming from the combination of Wellbutrin and alcohol. The Wellbutrin alone works well for me and keeps my depression from getting too bad. I have a history of alcoholism and depression in my family so maybe some of us who have a propensity towards alcoholism are more likely to experience the detrimental effects of combining Wellbutrin and Alcohol. (who knows) Either way – to those of you who are contemplating consuming alcohol while on Wellbutrin IT IS NOT WORTH THE RISK. Maybe you’re a person that has no problems with the combination (as some have written) but maybe you’re the person who will contemplate suicide or black out then cheat on a spouse or drive drunk because you are not in control of your mind or conscious of actions (like some above had found themselves doing). You risk harming yourself and harming, injuring or killing others. What if that intoxicated driver hadn’t seen a pedestrian crossing the road and struck them? Or wasn’t able to react quickly enough to avoid harm?
    I feel great on Wellbutrin and felt horrid on Wellbutrin and alcohol. STAY AWAY. DON’T DO IT. ITS NOT WORTH IT.

  44. I drank some wine last night while taking Wellbutrin. I am extremely sick to my stomach today with a minor headache. How long will this side affect last? I have been taking the drug for 6 days and want to stop taking it. Is it safe?
    Thank you

  45. I was taking 300 mg Wellbutrin…but down to 150, only because I dont like taking 300 all at once, and I cant seem to remember to take my 2nd dose..I dont know..it all feels the same..never feel ..great…mixing alcohol…I drink socially, but can certainly have one, of someTHING..wine, certain beer, a sip of B&B …I dont drink alot at once, just a little, often..Ive gotten trashed to the point of vomitting wondering how the hell it happened? Because I didnt consume that much! What else has happened is MIGRAINES! Migraines that make you vomit, and suffer in bed ALL.day, unless you are armed with Maxalt migraine meds…I dont see anything here regarding headaches…Im only now up and on my couch, its 5:10pm…I felt the migraine coming at 5am and I spent. all morning holding my forehead, and vomitting…I took Iboprophen, later Aleve and Zofram? Anti nausea med my daughter got from a bad virus she ended up with…NOTHING TOUCHED MY PAIN.til I finally managed to fall asleep..woke up noonish, nausea gone..but headache still pounding away…Been in bed alll day :(:(

  46. I was prescribed buproprion after a few days in the hospital during alcohol withdrawal. I didn’t take it all and have a few pills left. I’ve been drinking heavily the last 4 months, stopped about 6 hours ago and feel awful. Mild shakes, mild nasea, but the worst part is feeling like I’m losing it, I can’t think straight ir function very well. Is it okay to take a pill this soon (150 mg) or will it make things worse? I don’t intend to take it regularly, just the next few days to get though the withdrawal, and I don’t intend to drink anymore.

  47. Lydia……if it is illegal, why didn’t my doctor tell me? I actually told him what I drink along with wellbutrin and he told me to just be careful and if I notice anything out of the norm, just slack off. I don’t believe its illegal, I think you should just drink moderately. I drink 6 to 8 beers once at week.

    1. Hi, Janet. It’s definitely abusive, and you put yourself at risk. There are many cases that ended into the ER, and the amount of mixing Wellbutrin with alcohol that may harm you varies from person to person. However, if your doctor knew, then probably it’s fine to drink moderately. It’s your call after all.

  48. Could have me mixing wine with wellbutrin result in wellbutrin not being effective?I was doing OK on 150 mg till I made the.mistake of having wine one night and the next morning was all anxiety and panic attacks so my docter increased it too 300 mg it took more than a month to feel a little normal.

  49. Hi. I just started taking 75 mg (just 1 time a day) for autonomic dysfunction (I pass out a lot from low blood pressure) and so far it’s working. Am I allowed to indulge in a glass or two or wine a night on such a low dosage? I do not have depression or need to quit smoking, so I’m not sure if the other comments apply to me, as I am on the lowest dosage possible.

    1. Hi, Alex. Please consider that it is illegal to mix Wellbutrin (no matter the dose) with alcohol, and you put yourself at risk.

  50. I take 100 mg of wellbutrin 2x a day. When I drink, I drink at least a 6 pack of bud light or maybe a little more about 2x a week. I havent had any problems with it except being very shaky the next day and can’t think as well as usual. Is it really dangerous for me to mix or is this all that will happen? I like to drink when I’m off work because my mind can be at ease then and I feel happy. I suffer from depression and anxiety and I also take 40mg celexa once a day.

  51. Well, I took the risk and had a glass of champagne over Christmas. Nothing much happened, except it didn’t taste quite as good as I’d remembered. I’ve noticed a lot of things I used to have affection for don’t taste the same, like sugar and chocolate. On the upside, though, Indian food still tastes the same (if not better), and that’s my favorite food, so… all is well.

  52. After reading this page it’s a bit weird to say this but….It’s true I drink too much, martinis or vodka oj, etc….way too much, nightly. On New Years eve I told the bartender, this is my fourth in about 4 hours and I didn’t really feel it. Driving was no problem, my date was not concerned about my behavior or ability to drive, I had a couple more before the end of the evening and still she was not concerned so I mean to say, unless I drink too much in a short period of time, inebriation is not an obvious problem although I understand that it is a problem on many levels.
    I have come to realize that some of my thinking and behavior is not me its Bi-polar / hypomania (hate that word :(. I take 450 mg of the generic form of Welbutrin in the morning (300 mg and 150) along with 200 mg of Lamotrigine, last week increased to 250 mg. Zero effect on the Hypomania. The alcohol is a form of self medication. So….I’ve come to understand that much of my behavior is Hypomania although the confusing part is that it’s some of it’s manifestations are actually natural to my personality…course I’m not the best judge of that but I think thats the case. So, now I will embark on the guinea pig journey of finding the right meds…argh…and yes, the alcohol thing needs to be dealt with but what it masks needs to be dealt with first… arghh

  53. I’m about to start taking Wellbutrin for smoking cessation and am concerned about the “don’t suddenly stop drinking alcohol before taking Wellbutrin” because it heightens risks of seizures. This is confusing to me. Does this mean I should not drink for a week beforehand? Or a month? I have maybe 6 drinks a week. Does this qualify as suddenly STOPPING or are they talking about severe drinkers? Any help with this warning would be appreciated

  54. My bf just started bupropion 2 days ago what can happen if he drinks occasionally, like tonight for instance for new years?

  55. It’s New Year’s Eve and I would like to have a couple drinks tonight . But from what I’m reading it says it bad to drink at all . I take 2 15mg tablets at day. I have had a drink while taking
    These pills but not to where I’m drunk or anything mind

  56. I used to take 300 mg of Wellbutrin a day, twice when I wake up and one later in the day, but stopped because I had a bad rash and wasn’t sure if it was from the medication. I was told to stay off of it for a week, and before I stopped I only took 100 mg for the day. I didn’t have a rash then, so it was thought to not be from the medication. So after a week I was recommended to start at 100 mg again a day, which I have (no rash). But I’ve taken two days of it, and forgot yesterday’s and haven’t taken today’s. I want to drink alcohol do you think I am safe now to? It’s been two days since I’ve had any and it was only two days of 100 mg, because before then I was off of it. If I stop now will I be okay to drink tonight?

  57. Hi! I want to drink on new years but I currently take 200 mg of wellbutrin sr. I plan on skipping taking wellbutrin that morning, but will it be out of my system enough?

  58. So, having just started on it two days ago, is it OK to have one meager glass of champagne with Christmas Dinner and then on New Year’s Eve? I mean one small glass, not the whole bottle. A celebratory amount.

  59. It is the hoildays I just started Bupropion Sr 150MG Tablets a week ago no side affects. However it hoilday time is it okay to have a glass on wine. My doctor prescribed this medcine to help me lose weight not and help stop smoking I have stopped the smoking right away however I was a big smoker maybe 5 aday. I just wondering if a few hoilday drinks will hurt me while on this medcine.

    1. Hi Sherrill. I would still advise you to steer clear from the alcohol while on wellbutrin, even during the holidays. You’ve only been taking it shortly for your body to be able to get accustomed to the medication, and I fear you can start feeling really ill shortly after drinking. Maybe you can get some non-alcoholic beer or non-alcoholic wine to have on the festivities.

  60. I have taken Wellbutrin 150mg.SR for over 10 years. I have had only one major depressive episode during this time that required hospitalization. I usually have one-two glasses of wine with dinner and have not had a problem? Should I reconsider this? Also, recently; I have experienced a skin rash (itching and irritation on legs and arms. I have never had this before, but wonder if the rash might be related to the extended use of Wellbutrin.

  61. I have been taking bupropion for several years for anxiety. It was also used to quit smoking. I quit instantly with absolutely NO withdrawl, etc. My doctor said it works for some ,not for others. Worked like a charm for me for 9 years now! BUT I still drink alcohol, sometimes several per day. So far have not seen any side-effects, so I guess everyone is affected differently. Now I want to stop drinking completely but don’t dare to quickly by the things I read about stopping abruptly? But how do you stop “slowly” then? Someone know? Thanks.

  62. So I’ve been on Welbutrin for almost about 2 weeks.I’m not much of a drinker,my last drink was like a month ago and I was wondering if I have a drink now will I have any side effects?

  63. I drink about 3 to 4 glasses of wine about 3 time a week. I also take 2 mg of Ativan everyday for severe anxiety. Ive been taking Ativan for 10 years. The combination has not affected me for all this while. I would like to start taking Welbutrin due to my total absence of no libido. O have not have not had sexual desire for 4 to 5 years. I am 40 years old. I am frustrated and my marriage has almost failed because I don’t have ANY sexual desire. I just don’t know what to do. I enjoy having a glass of wine. My job is very stressful. Also, the wine enhances my sexual activity. I would appreciate your comments. Thanks.

  64. I have been taking this drug for about 15 years for mood. I’ve never been intoxicated. However, a handful of times a year I’ll have one glass of wine or a cocktail. Never experience anything odd in the past.
    Is it fair to say that since I’ve not noticed a side effect in the past, then to have one drink, is tolerable to my body?

  65. I started Wellbutrin 2 years ago for MDD. It has made a world of difference. Life is grand. I skip my dose if I suspect I will have a drink or two at social events. And I drink lightly. There have been no ill effects. Just because that works for md I don’t recommend it for everyone. It’s safer not to drink. The only time I have severe effects is when I run out of Wellbutrin and few days before payday and I have to choose between buying my kid’s meds or mine. Of course I put my kid first. Anyhow, I experience lethargy, fatigue, yawns and tingles. But the scariest thing is impulsive thoughts and behaviors. After 4 days off Wellbutrun, one day I grabbed my work knife and thought it would be a great idea to slice my wrist. Luckily I had enough smarts to not do it! I called the doctor, made a visit and took the day off. Never again will I be so dismissive about meds. All I had to do was ask for $5 for my copay. My pride almost severely injured me and could have cost me my job.

  66. I drank ALOT of alcohol at a wedding last weekend and got very sick and still a week later I feel as though I’m somewhat hungover. Could this be because I’m on welbutrin?

  67. snorting welbruten is extremely addictive people learn snorting will in prison or jail house invirement it gets you extremely high and will cause halutionation drinking alcohol take the sting out of the throat so you can even sniff more your head and nose will become numb I have been addicted to it for year sniffing 4 to 5 tablets in 2 to 3 house which can be 500 milagrams please tell me what I should do sincerely paul

  68. I have been taking 100mg of wellbutrin everyday for six months. I also drink several glasses of wine each day. I did not pay attention to the drug alcohol warnings. I want to stop drinking. How do I do this without serious side effects. Please help.
    Thank you

  69. I have been on welbutrin for a week. I am also on gabepentant and clonzapam. I take as prescribed..I started drinking heavy in the last few months..I feel better mentally. I was and am drinking for back pain…I didn’t drink for a couple days and my mind felt better.. I am wanting to continue to quit drinking..but now from all this reading i am scared to.. even though I feel better when I don’t drink…..

  70. I was put on Wellbutrin about a month ago for nicotine cessation. 150 mg. And upped to 300 mg. 12 days ago, I went on a 5 day drinking binge.
    When I stopped drinking I experienced moderate anxiety.
    My problem now is that I am experiencing dizziness. I hadn’t experienced any before the drinking. I’m experiencing slightly less dizziness everyday. Stupid me, I was unaware of the dangers of mixing the two.
    My question is will the dizziness go away? Did I do any kind of damage to my body. My Dr. Won’t be in until next Wednesday.

  71. Hi! So I started taking wellbutrin about a month and a half ago and I am on 300 mg XL once a day for depression and anxiety. The past few weeks I have noticed it helping me enormously! I am able to get out of bed and concentrate which is great because I am a junior in high school and can’t afford to miss school or get bad grades. Anyways, my schools prom is next weekend and I’m sure you know what I want to ask…is it okay to drink even just one or two shots? I haven’t had any alcohol since I started the drug because my doctor told me it reduces my seizure threshold. Obviously I don’t want that to happen however is that just something doctors HAVE to say even though it is rare unless consuming large amounts of alcohol. I am only 118 lbs so it doesn’t take much for me to feel a little drunk. I realize I am underage but I just would like an honest answer. Thanks!

  72. I tried 7 cocktails yesterday after taken 2 wellbutrins per day for 5 weeks, and the effect was that I seemed impervious for the alcohol effects during the first 2 hours, while my colleagues got drunk. After those 2 hours, I suddenly felt completely drunk too. So for me it postponed the drunkenness. I am a 30 yo male and weigh 80 kilos.

  73. I had a very bad experience mixing the two after my dosage was increased from 75mg 2x day to 100 mg 2x day. On 75 I had no issues drinking. After the increase I had one glass of wine and don’t remember much after that. I ended up having 5 glasses and taking two bottles of Wellbutrin and had to have my friend take me to the ER. I don’t know how I ended up being suicidal. I was upset about something that day but certainly not suicidal. The mix of alcohol and Wellbutrin seemed to intensify my emotions as well as the effects of the alcohol. It earned me a involuntary stay at a hospital for 6 nights. It was a real eye opener. I will never drink again on this medicine

  74. Hi there,

    I just came back from a one week vacation on a resort and I was drinking alcohol daily while there. However, I do not regularly drink alcohol. This was only because I was on vacation and social drinking. Would it be okay if I started taking bupropion one week after I returned from my vacation? I’ve read online that it is not recommend to start taking bupropion after chronic drinking and so I just wanted to make sure that my situation was okay.

  75. No question here, just a warning to others. I’m a regular social drinker. Took Contrave for weight control then eventually stopped due to the GI side effects. I didn’t drink at all while on the medicine as per doc’s orders. Over a week after stopping I decided to go out to the bar, thinking it was out of my system. Big mistake. I blacked out after only a few drinks but somehow still made it home by myself. I remember paying my tab, backing my truck out of the parking spot, then laying face down in my shower until the water was cold. Woke up feeling ok but virtually no memory of the previous evening. Truck was undamaged but parked sideways in my yard. Oh, and my phone was blowing up from several people asking if I was ok because I apparently texted them about how much my life sucks and that I wouldn’t be around in the morning. I’ve had some mighty high quantities of booze in the past, but I’ve never blacked out… let alone after only a few drinks. Yes, the Contrave has both wellbutrin and naxatrone but my experience is nearly identical to the horror stories I’ve heard about wellbutrin. Best bet… don’t ever mix medication and any amount of alcohol. Not before, during, or shortly after stopping the medication. It’s not worth the possibility of a bad reaction. My alcohol tolerance is high but after a few drinks I felt like I chugged every bottle in that bar.

  76. I have been on Wellbutrin for at least 3years, my Dr and I have tried quite a bit to get me off this HORRIBLE drug as it makes me so nuts, strange, outraged. Its horrible on it, horrible off of it, worse off. I go through drinking binges, I knew that alcohol and Wellbutrin were a horrible combination, but being on it for so long, I drink quite a bit…enough that usually my pancreas has to start scaring me enough to quit, but only long enough for it to calm down. I almost died about a yr ago from pancreatitis, my levels were at fatal level , had to be in the hospital for a week yada yada. For some reason I wasn’t aware that it could cause seizures to quit drinking while on Wellbutrin or that you had seizures on wellbutrin until I started reading these forums and comments.drinking the other day I flipped out something crazy don’t remember it. I hate this drug I hate wellbutrin does anyone know how to get off of it? Any comments or assistance would be wonderful.

  77. My doctor knew that I am a raging alcoholic.. when he prescribed this medicine. I have had adverse effects and quit cold turkey. No body told me I would withdraw… I thought I was having either a seizure or heart attack. Also dry heaving all day at work. How long will this last .. been about 20 days since I quit wellbutrin. Today was the worst

  78. Hi I have been on suboxone for many years & it is impossible to get out of your system. I desire with all of my heart to go to rapid detox. The problem is that it is very expensive & insurance doesnt cover it. Would you know of any organization that would help me? I am so ready for this nightmare to be over!!! Thanks is advance!!

  79. Can alcohol and Wellbutrin go the opposite way. Consumption of alcohol rises. I have recently been in the company of someone taking Wellbutrin and drinking alcohol. Although the person was intoxicated, they seemed to be fired up to carry on drinking. Ive known this person many years and although drank. it was always controlled.
    I personally took Paxil some years back and it made me feel like a million bucks and my alcohol consumption when up significantly each time I drank and I drank more often. When I quit taking Paxil i reverted back to my norm.

  80. I rarely ever drink… I used to be on Paxil 20mg and drinking wasn’t a problem. I’m off Paxil now due to side effects and have been on the lowest dosage of Bupropion (wellbutrin) for about a month with little side effects. Is it okay for me to have one or two alcoholic drinks?

    1. Hi Jamie. I wouldn’t advise you to put yourself at risk by taking them together. Please be reasonable.

  81. Thanks for explaining! Every time I drink (I have been taking Wellbutrin for a long time) I get violently ill, and hang overs are intolerable, and last at least two days. The last time I had a night out, and consumed 5 oz of alcohol, the hangover was hospital worthy. Needless to say, I no longer enjoy social drinking. Remaining on the Wellbutrin is of more value to me than the occasional party. Thanks for confirming that my alcohol intolerance is the by product of a drug interaction.

  82. In addition to my last message – I found this in my research: Some dopamine agonists have been shown to increase impulsive and addictive behaviors (Kolla BP, Mansukhani MP, Barraza R, Bostwick JM. (2010). Impact of dopamine agonists on compulsive behaviors: a case series of pramipexole-induced pathological gambling. Psychosomatics. 51(3):271-3.). This was quoted in an article discussing Alcohol and Dopamine from this very site. Wellbutrin is a dopamine agonist. So YES for those of us that want to control our drinking, wellbutrin may work against us. Clearly refraining from alcohol while on the drug is key.

  83. I have been on Wellbutrin XL 150mg for over four years (I did go off at one point but lasted three months). My interest in bupropion is that it elevates dopamine (apparently low dopamine runs in my family – addiction is present). My pharmacy just recently added a large red label on my prescription bottle to not drink alcohol while on medication. Understandably anyone who suffers from clinical depression should refrain from drinking alcohol for obvious reasons however a glass of wine or two is something I have always enjoyed and was’t quite willing to give up. Long story short, i have noticed that my ‘self-medicating’ has increased from one to two glasses of wine, and from 2-3 days per week to 4-6 days in the last two years. I don’t want to drink (it messes with my sleep) but I enjoy a drink – notice the torment here – I have no willpower. Robbie’s question below struck a nerve – does wellbutrin increase the craving for alcohol? I am wondering the same thing. Wish someone could answer that. For all those who don’t see/feel side effects of combining alcohol with this drug – looking back on four years, my tolerance to alcohol continues to diminish, I have had memory problems, I have acted out of character and lashed out or picked fights while drinking, and I have blacked out more than once. These effects are only getting worse and I finally realized that it’s likely from mixing the two. Thankfully I have not done anything that has gotten me in big trouble however, my point is – if it’s not happening to you yet, it creeps up slowly and it will. BE CAREFUL. You’re on this drug for a reason!

  84. I take 100mg. everyday and lately I notice that if I drink a few beers that over the next couple I start to really lose it. I start having thoughts and start imaging things that are not real just today it hit me again. On Monday I had a few beers in the afternoon and a couple more in the evening and on Wednesday I was convinced that my wife was having a affair. So if anyone wants my opinion don’t mix anything with these pills.

  85. I have been taking this medication for over a year. I have quit drinking because my tolerance has been drastically lowered since taking Wellbutrin. I would have three beers, feel completely out of control and drunk, then I would black out. I began to black out every time I drank, no matter the quantity. It was scary and not worth the risk to continue drinking.
    That being said, I recently changed my dose from 150 mg to 300 mg. The change has dramatically increased my energy, I know longer feel the need to take a nap everyday, I get up for work with no problem, I’m less irritated, and overall so much happier.

  86. If i take welliburtin I am more inclined to want a drink or two. If I dont take it I have more control to say no to having a drink. Doess bellbutrin make you want to drink.

  87. Mixing alcohol (in reasonable amounts) and wellbutrin could cause permanent brain damage? (eg. permanent memory damage, etc). I take one pill of wellbutrin XL 150mg at 10am every day. Should I skip one morning so I can drink 12 hours later? Thank you

  88. I told my doctor that I drank too much and she still prescribed Wellbutrin…have been on it a year and it’s def better than Citalopram if you drink that would make me black out bad…still once in awhile if I drink too much taking Wellbutrin it makes me crazy.. I can relate with “don’t drink” ‘s comment def scary..

  89. Erica, mixing alcohol and anti-depressants is a very bad idea. The side effects and dangers listed in the text above are real and can lead to serious consequences.

  90. Hi, I take 100 mg of Wellbutrin once a day
    I started doing this on June 23 but before that I was on it twice a day; one in the morning, one at night. I didn’t take it for like two weeks ‘cuz I couldn’t sleep ‘cuz of it so that’s when my doctor changed it to once a day-100 mg. I started taking the new one on the 23 of June and I’m going to a party on Saturday and I really do want to drink what do I do?

  91. Friday at about 6pm I took one of my wellbutrin pills, and half an hour later I took two more, then a couple of hours later I took two and twenty minutes later I took another totaling six. At 2 am the next morning, I threw up three times and couldn’t sleep. At 4pm the following same day I drank 2 glasses of sangrea and a half an hour later I projectile vomited. Since that friday, I’ve had this constant queasy feeling, headaches, sensitivity to light, constant confusion, and some memory loss. I called poison control and they highly recommended I go see a doctor, but my insurance doesn’t start til next week. What I’m feeling is definitely not normal. Also this was the first time I’ve taken my medication in about 2 months.

  92. I take 75mg of bupropion hcl 3 times a day and I also drink at least 2 to 6 beers a day and smoke weed 4 days a week and I have never ever got any negative side effects from mixing all three. I’m not saying that I condone this behavior, just saying that it doesn’t seem to effect me any different.

  93. I took this medication for quitting smoking and noticed some adverse reactions with alcohol. I would not recommend drinking while on it. It makes you more sensitive to alcohol. There are warnings for a reason.

  94. Hello, having awful side effect from taking this medicine and wondering is it because of drinking alcohol (while socializing, not abusing it) or maybe smoking weed? Please if any expert or someone who had expeciened also smoking weed while being on this medicine can provide me an answer, I’d be more than appriciated.

    Thank you very much

  95. I have been taking Wellbutrin for a year now.Last week i forgot to take my 300mg pill in the morning so i took at supper.Then i started drinking vodka.That night I cheated on my wife and had no i idea the next day at all.i would never cheat on anybody.It was like everything as normal and then i must of blacked out got caught red headed,,,,I said i was going to go jump in the freezing cold lake to kill my self and i am so not suicidal at all i love life and can’t wait to wake up in the morning.So my wife put me to bed and I have no memory of it happening and i didn’t even drink a lot just a pint or maybe less.Now my wife and i are splitting up because of the vivid seen she saw that night.Now i feel so bad I have never even cheated before and my wit is my best friend.Now i am losing here forever….So be very carful when drinking on this pill…I personally will not ever drink while I’m taking this pill…

    Sorry Angela
    I Love you

  96. Hi Terry. It’s best to avoid alcohol totally when on Wellbutrin, but you can consult your prescribing doctor or pharmacist to learn more about dosing timing if alcohol cannot be avoided. Also, record the symptoms you’ve experienced, date, time, frequency, duration, severity, etc. and report these symptoms to your doctor and/or pharmacist for feedback.

  97. When you say to not mix Wellbutrin with alcohol does it mean taking them at the same time, or that you should not consume alcohol at all while on the drug, regardless of the time that you take it?
    I have noticed that I have, what as best be described as head shudders, and was wondering if this could be a result of having an occasional glass of wine. I am on a very low dosage of welbutrin.


  98. @ Don’t Drink

    Wow. Thanks for your comment.

    Blackout drunk does happen with welbutrin; I’ve had it happen a few times. All I can say is that it’s really good that you’re safe. I can’t believe what you went through. You’re very lucky that you are still here today. I have heard of suicidal thoughts being a side-effect of antidepressants but never considered how that could be if compounded with alcohol.

    I’m very happy that you’re safe, and I’m very happy that you decided to share your experience here. I understand how you say you weren’t that bad before deciding to take welbutrin. I was the same. I was depressed but in no way suicidal; so it doesn’t mean that just because you took antidepressants, were you dangerously depressed. People take them for various reasons.

    In regards to the holistic route, one of the best ways to address depression is physical activity. Exercising by going to the gym or playing sports a few times a week plus being relatively active on your off days is by far the best way to naturally beat depression – better than antidepressants.

    Well, good to hear that you are safe, and I’m sorry to hear about the effects on your marriage. Good luck figuring that out. Maybe your husband will realize that he should be happy that you are still with us. If your relationship is strong you guys will overcome this.

    Take care

  99. I was just googling drinking and wellbutrin and came across your site. I feel I must share my horrific story. I’ve been on Wellbutrin for about 2 1/2 months. I have a few drinks a couple times a month and have had no ill effects of being on Wellbutrin. However, on Christmas Eve, just a few days ago I drank a lot more than normal, was having a great time, noticed I was a lot drunker than I should of been. My family hosted Christmas and after everyone left a simple conversation with my husband turned into complete hysteria for no reason. He’s a police officer and after he went to bed I went into his safe and took out his gun and contemplated my life. THIS IS NOT SOMETHING I’VE EVER THOUGHT ABOUT. I’m not a suicidal person, the thought never crossed my mind. After sitting in fetal position on the floor for an hour I put his gun back and went and told him I was suicidal and put his gun in my mouth as our family might be better off without me. I can’t stress enough that this is just not me. It was like an out of body experience. I’m so freaked out as is he on my safety and the safety of our children. I didn’t realize how dangerous it can be to drink. In addition I completely blacked out putting gifts under tree from Santa, etc. I wasn’t even that depressed when I went on them, I heard good things that Wellbutrin was a good pick me up and you can loose weight with it. I threw out my pills, so done with that. Going to go a holistic route with diet and meditation. Just be aware. I think I seriously damaged my marriage with this. I keep telling him it was the wellbutrin booze combo, but not sure he believes me. What a nightmare. Please heed my warning and be careful combining the two. We’ve been together for 15 years and this type of hysteria has never happened, ever.

  100. Hello Sandra. These are all great questions but should really be addressed to your prescribing physician or a pharmacist. These experts have more experience in side effects of Wellbutrin taken when drinking and can point you in the right direction. Good luck!

  101. Hi i have been on Wellbutrin for the last 7 months now and i am doing much better. I am on Wellbutrin to help me with a cronique mentrual syndrome.
    I take alchool regularly and i always have.
    I have never had any problems taking the two together . The only thing that bothers me is when i take a lot of alchool during a week-end and then get back to my weekly routine of not taking any alchool , Then for the first few nights after when i go to bed at night i am very tierd and want to fall asleep right away but then as soon as i fall asleep i go right into weird and lucid dreams . Almost like hallucinations. i Then wake up and fall right back to sleep and it starts all over again. this can go on for the whole night . The next day it gets a little better and by the third night i can manage a pretty good night of sleep. I would like to know if this is possible? that if it is the mixture of the alchool and wellbutrin that can cause this.
    I also read that it is not a good idea to stop drinking while on wellbutrin? I am going on a diet and want to help myself by not drinking for a few months . «Is this possible ?
    Thank you for your attention
    Sandra Gagnon

  102. I’m not much of a drinker. I’ve always had a very low tolerance, and I didn’t really notice any sort of relationship between wellbutrin and alcohol. I’ve been taking the antidepressant for about eight months now and am finally starting to notice an effect. It used to take me three drinks to feel drunk, now I only have to drink one.

    hangovers are definitely harder to get rid of, but never severe.

  103. I am currently taking Wellbutrin and have found no negative side effects while intoxicated or afterwards. I drink only occasionally, usually out at bars, taking shots of liquor. I have always had a low tolerance to alcohol, and I have not noticed a lowering of my tolerance. Blackouts can happen, along with loss of motor control, just like any time when you are drinking heavily. I have never had concern of a seizure, and I rarely get bad hangovers while on Wellbutrin.

  104. Hi, I have been taking Bupropion XL since December and I haven’t drank since before getting on the medication. I have an event this coming weekend that I will most likely be drinking at. I was wondering what the chances of a seizure are if I was to drink? And if I just simply don’t take my pill the day of the event, would that lessen the possible side effects?

  105. Hello Patty. This is a great question, but one that a qualified medical professional needs to answer. Please seek counsel from your prescribing doctor or a pharmacist.

  106. I started Wellbutrin 1 week ago and I have decided not to take it anymore. Because it’s only been a week,is it safe for me to just stop?

  107. Hello sandeep. Thanks for your question. On the medication guide for Wellbutrin, the manufacturer has warned:

    Do not drink a lot of alcohol while taking WELLBUTRIN. If you usually drink a lot of alcohol, talk with your doctor before suddenly stopping. If you suddenly stop drinking alcohol, you may increase your risk of having seizures.

    Although you may be able to drink small amounts of alcohol only occasionally while taking Wellbutrin, check with your doctor before considering this medication for long term use, if you know that you will be drinking while taking it.

  108. i take Alcohol twice a week.
    should i go in for Wellbutrin or not ?
    i can ignore Wellbutrin the day,I want to drink pls recommend

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